摘要:
Compounds represented by formula I: or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B′, X, Y, R1, R1′, R2, R2′, R3, R3′, R5, R5′, R6, m, n, or p are as defined herein, are useful for treating flaviviridae viral infections.
摘要:
A hub is disclosed for supporting and retaining at least one surface conditioning article relative to and spaced apart from a rotary shaft. The hub may be a hub of a brush assembly. The hub includes an arbor tube and a pair of plates. Shoulders are provided on the arbor tube and the plates are coupled to the arbor tube at a pre-determined distance set by shoulders. The surface conditioning article is provided between the plates. Since the distance between the plates is set by the shoulders, the density of the surface conditioning article between the face plates also is predetermined. The plates may include a key-shaped region with a circular portion and a keyseat. An adapter also may be provided. The adapter is configured and dimensioned to be engaged in the key-shaped region, permitting a shaft having a smaller diameter to be coupled to the hub.
摘要:
A system for accepting conventional wire in bulk form, cutting the wire into predetermined lengths and preparing the ends of the wire for use in conventional wire harnesses is disclosed. More specifically, the system accepts as input data, in digital form, which fully describes each wire to be formed. Individual wires having the required length are cut from wire provided in bulk form. As each section of wire is measured and cut, it is stored in individual containers and the ends of each section is secured by a clamp. A transport system sequentially transports the stored wires to workstations where conventional wire preparation tasks such as stripping, marking and attachment of terminals are performed. After all wire preparation functions have been performed, the individual wires are removed from their containers and utilized in forming wire harnesses.
摘要:
An optical system providing multiple wavelength dependent optical paths and using graded index of refraction optical elements is disclosed. The dimensions of the graded index of refraction optical elements are selected such that each optical path is one focusing length. Dichroic elements are utilized to differentiate between the optical paths on a wavelength basis.
摘要:
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
摘要:
An operator MUX interface (OMI) (102) includes a data base manager (203) that manages at least two data bases. The first comprises a substantially non-temporary data base, and the second comprises a substantially temporary data base. The latter includes information from both the first data base, and other information as well. The data base manager (203) automatically alters the data storage structure of the second data base whenever either the data storage structure for the first data base is changed, or whenever new information must be added to the second data base, and the data storage structure of the second data base will not readily accommodate that addition.
摘要:
The communications system may include wireless two-way communications equipment having selectable functions and various operational features. Control modules each include mechanisms for providing indicia representative of the status of the features of the communications equipment and mechanisms for generating data for controlling the functions to be selected on the communications equipment. A group of the control modules are coupled to a panel module which selectively communicates with each of the control modules in the group. An interface circuit is coupled to a plurality of the panel modules for selectively communicating with each; the interface circuit includes a microprocessor for writing indicia data to each of the selected control modules via the selected panel module and reads the control data generated by the control modules. The periodic scanning and reading of information is utilized to ascertain changes in the data.
摘要:
When a standard business office communication system is combined with ACD features, it is necessary to design the system to accommodate a variety of operational modes. Two such modes are handset operation, where a station user talks and listens via a conventional hand-held instrument, and headset operation where the user has an earphone and mouthpiece supported by the head. In headset operation, the station is made to appear off-hook permanently and incoming calls are signaled by a short burst of audio tone followed by an automatic connection to the called party. In handset operation, ringing signals must be applied to the station, and these signals continue until the incoming call is answered by a subsequent off-hook condition of the station. The disclosed arrangement allows each station to operate in either mode on a per call basis.