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公开(公告)号：US5882472A
公开(公告)日：1999-03-16
申请号：US797389
申请日：1997-02-07
Applicant: Geoffrey William Vernon , James Goodwin , Andrew Cleall , Thomas William Bailey
Inventor： Geoffrey William Vernon , James Goodwin , Andrew Cleall , Thomas William Bailey
CPC classification number: B65B29/04 , B29C65/18 , B29C65/305 , B29C66/0342 , B29C66/472 , B29C66/69 , B29C66/8181 , B29C66/82263 , B29C66/83411 , B29C66/83415 , B29C66/83511 , B31D1/023 , B29C66/71 , B29C66/81821 , B29L2031/7128 , Y10T156/1077 , Y10T156/1734 , Y10T156/1739 , Y10T428/24025 , Y10T428/24041 , Y10T428/24215 , Y10T428/24777 , Y10T428/24793
Abstract: A tagged packet carries a tag which is attached to the main body of the packet by a thread. The thread comprises polypropylene so as to be attachable by heat sealing to the body. The body is made up of layers of sheet material also comprising thermoplastic material to allow the body to be closed by heat seals. The thread is secured to the face of the body at one edge at the same time as that edge is heat sealed and the heating for the thread seal is applied from the opposite face of the body whereas the adjacent regions of edge seal spaced from the thread has the heating applied through the first face. This arrangement gives closer control of the different conditions required for securing the thread and for sealing together only the sheet material of the body.
Abstract translation: 标记的分组携带标签，该标签通过线程附加到分组的主体。 螺纹包括聚丙烯，以便通过热密封附着到身体上。 该主体由也包括热塑性材料的片材层组成，以允许身体通过热封来封闭。 在该边缘被热密封的同时，螺纹在一个边缘处固定到主体的表面，并且螺纹密封的加热从主体的相对面施加，而相邻的边缘密封区域与螺纹间隔开 通过第一面施加加热。 这种布置可以更好地控制固定螺纹所需的不同条件，并且仅将身体的片材密封在一起。
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公开(公告)号：US5874149A
公开(公告)日：1999-02-23
申请号：US795050
申请日：1997-02-05
Applicant: Geoffrey William Vernon , James Goodwin , Andrew Cleall , Thomas William Bailey
Inventor： Geoffrey William Vernon , James Goodwin , Andrew Cleall , Thomas William Bailey
CPC classification number: B65B29/04 , B29C65/18 , B29C65/305 , B29C66/0342 , B29C66/472 , B29C66/69 , B29C66/8181 , B29C66/82263 , B29C66/83411 , B29C66/83415 , B29C66/83511 , B31D1/023 , B29C66/71 , B29C66/81821 , B29L2031/7128 , Y10T156/1077 , Y10T156/1734 , Y10T156/1739 , Y10T428/24025 , Y10T428/24041 , Y10T428/24215 , Y10T428/24777 , Y10T428/24793
Abstract: A tagged packet carries a tag which is attached to the main body of the packet by a thread. The thread comprises polypropylene so as to be attachable by heat sealing to the body. The body is made up of layers of sheet material also comprising thermoplastic material to allow the body to be closed by heat seals. The thread is secured to the f ace of the body at one edge at the same time as that edge is heat sealed and the heating for the thread seal is applied from the opposite face of the body whereas the adjacent regions of edge seal spaced from the thread has the heating applied through the first face. This arrangement gives closer control of the different conditions required for securing the thread and for sealing together only the sheet material of the body.
Abstract translation: 标记的分组携带标签，该标签通过线程附加到分组的主体。 螺纹包括聚丙烯，以便通过热密封附着到身体上。 该主体由也包括热塑性材料的片材层组成，以允许身体通过热封来封闭。 螺纹在该边缘被热密封的同时在一个边缘处固定到主体的顶部，并且螺纹密封的加热从主体的相对面施加，而边缘密封件的相邻区域与 螺纹具有通过第一面施加的加热。 这种布置可以更好地控制固定螺纹所需的不同条件，并且仅将身体的片材密封在一起。
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公开(公告)号：US5806392A
公开(公告)日：1998-09-15
申请号：US832129
申请日：1997-04-03
Applicant: Andrew John Cleall , James Goodwin , Geoffrey William Vernon , Peter Ernest Willett
Inventor： Andrew John Cleall , James Goodwin , Geoffrey William Vernon , Peter Ernest Willett
CPC classification number: B26D7/1818 , B65B61/08 , Y10T83/21 , Y10T83/2107 , Y10T83/2192 , Y10T83/2194
Abstract: Shaped articles are cut from a web by correspondingly shaped cutters on a drum cooperating with an anvil drum. The web is engaged by conveyor bands which pass around the cutter and anvil drums and form a continuing conveying path for the web away from the drums. The conveyor bands are clear of the article shapes cut in the web which can thus be positively separated from the web by pusher means to be drawn away from the web by their own conveying means.
Abstract translation: 通过与砧座鼓协作的滚筒上的相应形状的切割器从网上切割成形制品。 纸幅由传送带接合，传送带穿过切割器和砧座鼓，并形成用于纸幅远离鼓的连续输送路径。 输送带没有纸幅中切割的物品形状，因此可以通过推动器装置将其与纸幅正确分离，以通过其自身的输送装置从纸幅中拉出。
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公开(公告)号：US12012943B2
公开(公告)日：2024-06-18
申请号：US17984826
申请日：2022-11-10
Applicant: James Goodwin
Inventor： James Goodwin
CPC classification number: F03D9/46 , F03D1/04 , F03D9/25 , F05B2220/706 , F05B2240/9113 , H02K7/1004 , H02K7/1838
Abstract: A wind turbine assembly for covering wind energy into electrical energy includes a housing that is positioned adjacent to a roadway. An intake chute is integrated into the housing and the intake chute is oriented to face oncoming traffic on the roadway thereby facilitating the intake chute to direct wind produced by the oncoming traffic into the housing. A wind turbine is rotatably disposed within the intake chute such that the wind turbine is rotated by the wind produced by the oncoming traffic. A generator is positioned in the housing and the generator is in mechanical communication with the wind turbine. The generator is rotated when the wind turbine rotates to convert wind energy into electrical energy.
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公开(公告)号：US09029336B2
公开(公告)日：2015-05-12
申请号：US12629186
申请日：2009-12-02
Applicant: Christopher Liddle , Bryan James Goodwin
Inventor： Christopher Liddle , Bryan James Goodwin
CPC classification number: C12Q1/6897 , A01K2267/0393
Abstract: An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression, and uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals.
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Patent Agency Ranking
26.发明申请Transgenic Animals for Analyzing CYP3A4 Cytochrome P450 Gene Regulation 失效用于分析CYP3A4细胞色素P450基因调控的转基因动物公开(公告)号：US20120171690A1
公开(公告)日：2012-07-05
申请号：US12855383
申请日：2010-08-12
Applicant: Christopher Liddle , Bryan James Goodwin , Graham Robertson
Inventor： Christopher Liddle , Bryan James Goodwin , Graham Robertson
IPC: C12Q1/68 , C12N5/10 , G01N21/17 , A01K67/027
CPC classification number: C12N15/8509 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/10 , A01K2227/105 , A01K2267/03 , A01K2267/0393 , A61K49/0008 , C12N9/0077
Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human.
Abstract translation: 本发明涉及产生非人转基因动物，其包含用于产生可检测量的报告分子的报道构建体，所述报道分子可操作地连接于来自位于基因转录位点的起始点之间的人CYP3A4基因的转录调节核酸分子，和 位于位于该位点上游13,000个核苷酸的位置。 本发明还涉及这些动物用于测定化合物，特别是但不排除地，异生物或类固醇对人类CYP3A4基因表达调节的影响的用途。
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公开(公告)号：US08178168B2
公开(公告)日：2012-05-15
申请号：US11577914
申请日：2005-10-12
Applicant: Liam O'Neill , Lesley Ann O'Hare , Andrew James Goodwin
Inventor： Liam O'Neill , Lesley Ann O'Hare , Andrew James Goodwin
IPC: C08J7/16
Abstract: A method for forming a polymeric coating on a substrate surface, by plasma treating a mixture comprising a free-radical initiated polymerisable monomer having one or more free-radical polymerisable groups in the presence of a free radical initiator, wherein said plasma treatment is a soft ionisation plasma process (a process wherein precursor molecules are not fragmented during the plasma process and as a consequence, the resulting polymeric coating has the physical properties of the precursor or bulk polymer) aid depositing the resulting polymeric coating material onto a substrate surface.
Abstract translation: 通过在自由基引发剂的存在下，通过等离子体处理含有具有一个或多个自由基可聚合基团的自由基引发的可聚合单体的混合物在基材表面上形成聚合物涂层的方法，其中所述等离子体处理是软的 电离等离子体工艺（其中前体分子在等离子体工艺期间不分裂的过程，因此所得聚合物涂层具有前体或本体聚合物的物理性质）有助于将所得聚合物涂层材料沉积到基底表面上。
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公开(公告)号：US20090307785A1
公开(公告)日：2009-12-10
申请号：US12430672
申请日：2009-04-27
Applicant: Christopher Liddle , Bryan James Goodwin , Graham Robertson
Inventor： Christopher Liddle , Bryan James Goodwin , Graham Robertson
IPC: A01K67/027 , C12N5/06
CPC classification number: C12N15/8509 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/10 , A01K2227/105 , A01K2267/03 , A01K2267/0393 , A61K49/0008 , C12N9/0077
Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human.
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公开(公告)号：US07531712B2
公开(公告)日：2009-05-12
申请号：US10415607
申请日：2001-11-01
Applicant: Christopher Liddle , Bryan James Goodwin , Graham Robertson
Inventor： Christopher Liddle , Bryan James Goodwin , Graham Robertson
CPC classification number: C12N15/8509 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/10 , A01K2227/105 , A01K2267/03 , A01K2267/0393 , A61K49/0008 , C12N9/0077
Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steriod, on the regulation of expression of the CYP3A4 gene in a human.
Abstract translation: 本发明涉及产生非人转基因动物，其包含用于产生可检测量的报告分子的报道构建体，所述报道分子可操作地连接于来自位于基因转录位点的起始点之间的人CYP3A4基因的转录调节核酸分子，和 位于位于该位点上游13,000个核苷酸的位置。 本发明还涉及这些动物用于确定化合物，特别是但不排除地，异生物或抑制剂对人类CYP3A4基因表达调节的影响的用途。
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公开(公告)号：US6041980A
公开(公告)日：2000-03-28
申请号：US967616
申请日：1997-11-11
Applicant: James Goodwin , James Robert Stembridge
Inventor： James Goodwin , James Robert Stembridge
CPC classification number: B65B39/004 , B65B1/36 , B65B29/02
Abstract: A valve (16) reciprocates with a constant stroke in the former tube (2) of a form-fill apparatus to dispense doses of filling material from the tube by ejecting the material through an outlet nozzle (8). The size of the doses is adjustable, in one form of the invention, by feeding the material is fed through an adjustable dosing opening immediately adjacent the valve. In another form of the invention, the valve (16) is adjustably positionable relative to the former tube (2) to vary the mean position of reciprocation of the valve relative to the tube. In a further form of the invention, an adjustably controllable head of material is maintained in the former tube to determine the rate at which it is fed to the valve (16).
Abstract translation: 阀（16）在成形填充设备的前管（2）中以恒定行程往复运动，通过将材料喷射通过出口喷嘴（8）从管中分配剂量的填充材料。 剂量的大小是可调节的，在本发明的一种形式中，通过进料，材料通过紧邻阀门的可调配量开口进料。 在本发明的另一种形式中，阀（16）相对于前一管（2）可调节地定位，以改变阀相对于管的往复运动的平均位置。 在本发明的另一形式中，在前一管中保持可调节的材料头，以确定其被供给到阀（16）的速率。
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