Method for producing optically active 3,5-dihydroxycarboxylic acid derivative
    21.
    发明授权
    Method for producing optically active 3,5-dihydroxycarboxylic acid derivative 失效
    光学活性3,5-二羟基羧酸衍生物的制造方法

    公开(公告)号:US06998495B2

    公开(公告)日:2006-02-14

    申请号:US10492507

    申请日:2002-10-24

    CPC classification number: C07C67/31 C07B2200/07 C07C67/29 C07C69/78 C07C69/675

    Abstract: A method for producing an optically active 3,5-dihydroxyhexanoic acid derivative by stereoselectively reducing an optically active 3-oxo-5-hydroxyhexanoic acid derivative is provided. The method, which requires neither an ultralow-temperature reactor, an incubator, nor protection of the 5-position hydroxy group, is simple and economical.An optically active 3,5-dihydroxyhexanoic acid derivative is produced by asymmetrical hydrogenation of an optically active 3-oxo-5-hydroxyhexanoic acid derivative catalyzed by an RuBr2BINAP complex prepared from a ruthenium complex and a ruthenium-optically active phosphine complex, i.e., 2,2′-bisdiarylphosphino-1,1′-binaphthyl (BINAP), while using extremely inexpensive hydrogen as the reductant.

    Abstract translation: 提供了通过立体选择性还原旋光性3-氧代-5-羟基己酸衍生物制备光学活性3,5-二羟基己酸衍生物的方法。 既不需要超低温反应器,培养箱也不需要保护5位羟基的方法简单经济。

    Film bulk acoustic wave resonator
    22.
    发明申请
    Film bulk acoustic wave resonator 有权
    薄膜体声波谐振器

    公开(公告)号:US20050189846A1

    公开(公告)日:2005-09-01

    申请号:US11028992

    申请日:2005-01-03

    CPC classification number: H03H9/02094 H03H9/175 H03H9/176

    Abstract: A film bulk acoustic wave resonator of the invention includes a substrate; a resonant structure provided on the substrate constituted by a lower electrode, a piezoelectric film and an upper electrode; and an acoustic multilayer of a plurality of reflective films provided between the substrate and the resonant structure. At least one of the reflective films of the acoustic multilayer has a specified crystal plane orientation, and an X-ray rocking curve full width at half maximum that is preferably not greater than 10 degrees, and more preferably is not greater than 3 degrees. This makes it possible to obtain better resonance characteristics than in the case of the prior art, by increasing the efficiency with which bulk waves propagating towards the substrate are reflected.

    Abstract translation: 本发明的薄膜体声波谐振器包括:基板; 设置在由下电极,压电膜和上电极构成的基板上的谐振结构; 以及设置在所述基板和所述谐振结构之间的多个反射膜的声学多层。 声学多层反射膜中的至少一个具有指定的晶面取向,并且X射线摇摆曲线半峰全宽优选不大于10度,更优选不大于3度。 这使得通过提高向衬底传播的体波的效率被反射,可以获得比现有技术的情况更好的谐振特性。

    Substituted acetylpridine derivatives and process for the preparation of intermediates for optically active beta-3 agonist by the use of the same
    27.
    发明授权
    Substituted acetylpridine derivatives and process for the preparation of intermediates for optically active beta-3 agonist by the use of the same 失效
    取代的乙酰嘌呤衍生物和通过使用它们制备光学活性β-3激动剂的中间体的方法

    公开(公告)号:US06515134B1

    公开(公告)日:2003-02-04

    申请号:US09926021

    申请日:2001-11-07

    Abstract: It is an objective to produce intermediates of optically active beta-3 adrenaline receptor agonists from readily available raw materials in a safe, efficient and industrially advantageous manner. A substituted acetylpyridine derivative represented by the general formula (9) is reduced by enantioselective reduction to produce an optically active hydroxyethyl derivative represented by the general formula (10) (wherein * represents an asymmetric carbon atom), and it is further derivatized to an intermediate of an optically active beta-3 adrenaline receptor agonist, such as an optically active dihydroxyethylpyridine derivative represented by the general formula (14) or an optically active oxirane derivative represented by the general formula (16).

    Abstract translation: 目的是以安全,有效和工业上有利的方式从容易获得的原料生产光学活性β-3肾上腺素受体激动剂的中间体。 由通式(9)表示的取代的乙酰基吡啶衍生物通过对映选择性还原而被还原,以制备由通式(10)表示的光学活性羟乙基衍生物(其中*表示不对称碳原子),并进一步衍生为中间体 的光学活性β-3肾上腺素受体激动剂,例如由通式(14)表示的光学活性二羟基乙基吡啶衍生物或由通式(16)表示的光学活性环氧乙烷衍生物。

    Processes for producing &bgr;-halogeno-&agr;-amino-carboxylic acids and phenylcysteine derivatives and intermediates thereof
    28.
    发明授权
    Processes for producing &bgr;-halogeno-&agr;-amino-carboxylic acids and phenylcysteine derivatives and intermediates thereof 失效
    制备β-卤代-α-氨基 - 羧酸和苯基半胱氨酸衍生物的方法及其中间体

    公开(公告)号:US06372941B1

    公开(公告)日:2002-04-16

    申请号:US09582461

    申请日:1999-08-16

    Abstract: An industrially advantageous method of producing &bgr;-halogeno-&agr;-aminocarboxylic acids is provided. Methods are also provided of producing optically active N-protected-S-phenylcysteines having high optical purity and of intermediates thereof, respectively, in which the above production method is utilized. A method of producing &bgr;-halogeno-&agr;-aminocarboxylic acids or salts thereof is disclosed which comprises halogenating the hydroxyl group of a &bgr;-hydroxy-&agr;-aminocarboxylic acid (in which the basicity of the amino group in &agr;-position is not masked by the presence of a substituent on said amino group) or a salt thereof with an acid with a halogenating agent. A method of producing optically active N-protected-S-phenylcysteines represented by the general formula (3) or salts thereof is further disclosed which comprises applying the above production method to optically active serine or a salt thereof and then carrying out treatment with an amino-protecting agent and reaction with thiophenol under a basic condition.

    Abstract translation: 提供了产生β-卤代-α-氨基羧酸的工业上有利的方法。 还提供了分别制备具有高光学纯度的光学活性N-保护的S-苯基半胱氨酸及其中间体的方法,其中使用上述制备方法.1。制备β-卤代-α-氨基羧酸或其盐的方法 其中包括将β-羟基-α-氨基羧酸的羟基(其中在所述氨基上不存在取代基的α-位置上的氨基的碱性)或其盐与卤素化反应 具有卤化剂的酸。 进一步公开了制备由通式(3)表示的光学活性N-保护的S-苯基半胱氨酸或其盐的方法,其包括将上述制备方法应用于光学活性丝氨酸或其盐,然后用氨基 保护剂和与苯硫酚在基本条件下的反应。

    Push-button switch, and operation device and teaching pendant comprising the same
    29.
    发明授权
    Push-button switch, and operation device and teaching pendant comprising the same 有权
    按钮开关,以及包括该按钮开关的操作装置和示教器

    公开(公告)号:US06288352B1

    公开(公告)日:2001-09-11

    申请号:US09415497

    申请日:1999-10-12

    Abstract: A push-button switch provided with a hollow push button, a case supporting it, and a switching mechanism having a first contact disposed within the case and a second contact disposed opposite to the first contact, with one of its ends being inserted into a hole of the push button. Within a hole formed in an inserted section of the switching mechanism, a slide block is provided slidably in a direction crossing the direction in which the push button is pushed. A slope capable of engaging with a slope of the hole of the push button is formed on the slide block. A coil spring (return spring) for energizing a shaft of the switching mechanism so as to abut the push button is provided on the bottom of the case. This configuration enables the push button to take up a first OFF state, an ON state and a second OFF state in order of depression.

    Abstract translation: 具有中空按钮的按钮开关,支撑它的壳体,以及具有设置在壳体内的第一触点和与第一触点相对设置的第二触点的开关机构,其一端插入孔 的按钮。 在形成在切换机构的插入部分中的孔内,滑动块沿与推动按钮的方向交叉的方向可滑动地设置。 在滑块上形成能够与按钮的孔的斜面接合的斜面。 用于对切换机构的轴进行激励以抵靠按钮的螺旋弹簧(复位弹簧)设置在壳体的底部。 该配置使得按钮能够按照按钮的顺序占据第一OFF状态,ON状态和第二OFF状态。

    Method of processing desulfurization absorption liquid and apparatus therefor
    30.
    发明授权
    Method of processing desulfurization absorption liquid and apparatus therefor 有权
    脱硫吸收液处理方法及其设备

    公开(公告)号:US06254771B1

    公开(公告)日:2001-07-03

    申请号:US09355799

    申请日:1999-08-04

    CPC classification number: B03D1/028 B01D47/06 B01D53/502 B03D1/1462 B03D1/247

    Abstract: This invention relates to a method for the treatment of a desulfurization absorbing fluid after gas-liquid contact with combustion exhaust gas in which fine particles of unburned carbon and other materials are efficiently removed from the desulfurization absorbing fluid to improve the quality of a by-product (e.g., gypsum) obtained therefrom. The method of this invention comprises the steps of feeding a gas into a desulfurization absorbing fluid (A) containing fine particles of unburned carbon and other materials and thereby producing gas bubbles so as to cause the fine particles to adhere to the surfaces of the gas bubbles and create a foam phase (D) consisting of the gas bubbles; and breaking the foam phase (D) to obtain a liquid (E) containing the fine particles.

    Abstract translation: 本发明涉及一种在与燃烧废气接触气液之后处理脱硫吸收液的方法,其中将未燃碳和其它材料的细颗粒从脱硫吸收液中有效地除去以提高副产物的质量 (例如,石膏)。 本发明的方法包括以下步骤:将气体供给到含有未燃烧碳和其他材料的微粒的脱硫吸收液(A)中,由此产生气泡,以使细颗粒附着在气泡的表面 并产生由气泡组成的泡沫相(D); 并破坏泡沫相(D)以获得含有微粒的液体(E)。

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