Abstract:
This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
Abstract:
This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
Abstract:
This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
Abstract:
This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
Abstract:
Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology.
Abstract:
A method of wireless communication over the reverse link. The method may include evaluating a reverse link loading. This evaluation step may involve examining at least two resources associated with reverse link loading within a first time period. Thereafter, a message is broadcast containing information regarding the availability of resources. This message is generated in response to the evaluated reverse link loading. This availability of resources message may correspond with an overload condition, increasing a number of active connections, decreasing the number of active connections, increasing an available transmit rate, maintaining the available transmit rate and/or decreasing the available transmit rate. In one example, the availability of resources message comprises a reverse activity bit.
Abstract:
This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
Abstract:
In a method for determining transmission latency in a wireless network, data packets addressed to a wireless unit are received at a radio network controller (RNC) and forwarded to a base station in communication with the wireless unit for transmission over the forward link. The RNC keeps track of when it receives the packets. Periodically, the base station sends messages back to the RNC. Each message identifies a data packet and the time it was transmitted to the wireless unit. The RNC uses the messages to calculate a data transfer rate, e.g., the number of packets between the first packet received by the RNC and the packet identified in the message, divided by the time difference between the message and when the first packet was received by the RNC. The RNC then applies the transfer rate to any data remaining for the wireless unit, to determine the transmission latency thereof.
Abstract:
A method is disclosed for determining when a request for a higher transmission rate should be granted to a mobile station that currently has access to a communication system to facilitate the maintenance of a performance target (quality of service level) of the reverse link. The method for determining when a mobile station can have access to a higher transmission rate includes obtaining first and second estimated performance indicators for a reverse link of the base station that a mobile station is currently accessing. A blocking threshold value is established. Access at the requested higher transmission rate is based on a comparison of the first and second indicators relative to the established blocking threshold value. If access is denied at the requested higher rate, access will be granted at the next lower rate which will not degrade the performance of the wireless communication system.
Abstract:
A ceramic particulate material which comprises particles having an irregular three dimensional surface profile having jagged projections and a median particle diameter of 200 micrometers or less, the particles being fractals produced by comminution of foamed ceramic material. The material may be such that in a sphere of rotation of the particle, from 30% to 80% of the volume of the sphere is void, the remainder being continuous solid material. The material may be produced by a process which includes providing a suspension of ceramic forming particles e.g., of an aluminosilicate such as clay, in a liquid medium; incorporating a gas in the liquid medium before or after formation of the suspension therein to produce a foamed suspension; extruding the foamed suspension; optionally drying the extrudate formed thereby; calcining the extrudate; and comminuting the calcined material, e.g. by crushing. The material may be used as a substitute for diatomite.