-
公开(公告)号：US10188355B2
公开(公告)日：2019-01-29
申请号：US15065042
申请日：2016-03-09
Inventor： Shivraman Giri , Robert R. Edelman , Ioannis Koktzoglou
IPC: A61B5/00 , A61B5/055 , G01R33/3875 , G01R33/48 , G01R33/483 , G01R33/56
Abstract: Embodiments relate to a method and system to improve fat suppression and reduce motion and off-resonance artifacts in magnetic resonance imaging (MRI) by using a background-suppressed, reduced field-of-view (FOV) radial imaging. The reduction of such artifacts provides improved diagnostic image quality, higher throughput of MRI scans for the imaging center, and increased patient comfort. By using a small FOV radial acquisition that only encompasses the structures of interest, structures that cause motion artifacts, such as the anterior abdominal wall, bowel loops, or blood vessels with pulsatile flow, are excluded from the image. According to an embodiment, combining a small FOV radial acquisition with one or more background-suppression techniques minimizes the impact of artifacts caused by anatomy outside of the FOV.
-
公开(公告)号：US20180110424A1
公开(公告)日：2018-04-26
申请号：US15332107
申请日：2016-10-24
Inventor： Shivraman Giri , Robert R. Edelman , Ioannis Koktzoglou , Himanshu Bhat
IPC: A61B5/026 , A61B5/055 , A61B5/0402 , A61B5/00 , G01R33/563
CPC classification number: A61B5/0263 , A61B5/7285 , G01R33/4835 , G01R33/5607 , G01R33/5635
Abstract: A method for producing an image representative of the vasculature of a subject using a MRI system includes the acquisition of a signal indicative of a subject' cardiac phase. During each heartbeat of the subject, image slices of a volume covering a region of interest (ROI) within the subject are acquired by applying a volume-selective venous suppression pulse to suppress (a) venous signal for an upper slice in the ROI; (b) venous signal for slices that are upstream for venous flow in the ROI; and (c) background signal from the upstream slices. Next, a slice-selective background suppression pulse is applied to suppress background signal of the upper slice. Following a quiescent time interval, a spectrally selective fat suppression pulse is applied to the entire volume to attenuate signal from background fat signal. Then, a simultaneous multi-slice acquisition of the upper slice and the upstream slices is performed.
-
23.发明申请Methods and Systems for Acquiring Multiple Interleaved Slices in Magnetic Resonance Imaging 有权用于在磁共振成像中获取多个切片的方法和系统公开(公告)号：US20150285884A1
公开(公告)日：2015-10-08
申请号：US14242924
申请日：2014-04-02
Inventor： Shivraman Giri , Robert R. Edelman , Xiaoguang Lu , Carmel Hayes
CPC classification number: A61B5/0073 , A61B5/0037 , A61B5/0044 , A61B5/055 , A61B5/7292 , A61B2576/023 , G01R33/4818 , G01R33/4835 , G01R33/4838 , G01R33/5635
Abstract: A method for operating a Magnetic Resonance (MR) imaging system including generating radio frequency (RF) excitation pulses in a volume of patient anatomy that includes a patient's heart to provide subsequent acquisition of associated RF echo data and generating slice select magnetic field gradients for phase encoding and readout RF data acquisition in the volume of patient anatomy. The method also includes acquiring a plurality of slices of an image of the volume of patient anatomy within a plurality of cycles representing time period between successive beats of the patient's heart. The method also includes causing, by a control processor, accelerated acquisition of two or more slices of the plurality of slices within a quiescent phase of each of the plurality of cycles. The method further includes applying, by the control processor, one or more saturation areas proximate to a target volume of the patient anatomy.
Abstract translation: 一种用于操作磁共振（MR）成像系统的方法，包括在患者解剖结构的体积中产生射频（RF）激发脉冲，其包括患者的心脏，以提供随后的相关RF回波数据的获取并产生相位的切片选择磁场梯度 编码和读取RF数据采集在患者解剖体积中。 该方法还包括在表示患者心脏的连续搏动之间的时间周期的多个周期内获取患者解剖体积的图像的多个切片。 该方法还包括通过控制处理器在多个周期中的每个周期的静止阶段内加速采集多个切片的两个或多个切片。 该方法还包括由控制处理器应用靠近患者解剖结构的目标体积的一个或多个饱和区域。
-
24.发明申请METHOD OF USING THE DETECTION OF EARLY INCREASE IN MICROVASCULAR BLOOD CONTENT TO DISTINGUISH BETWEEN ADENOMATOUS AND HYPERPLASTIC POLYPS 有权检测微血管内容物中早期增加的检测方法与ADENOMATOUS和HYPERPLASTIC POLYPS之间的差异公开(公告)号：US20130303861A1
公开(公告)日：2013-11-14
申请号：US13839234
申请日：2013-03-15
Inventor： Vadim BACKMAN , Hemant ROY , Young L. KIM , Michael SIEGEL , Vladimir TURZHITSKY
IPC: A61B5/0205 , A61B5/1455 , A61B5/145 , A61B5/1459 , A61B5/026
CPC classification number: A61B5/0205 , A61B5/0075 , A61B5/0084 , A61B5/0091 , A61B5/0261 , A61B5/14535 , A61B5/14546 , A61B5/14551 , A61B5/1459 , A61B5/4255 , A61B2562/0233
Abstract: The present invention, in one aspect, relates to a method for distinguishing between possible adenomatous and hyperplastic polyps using what :is referred to as “Early Increase in microvascular Blood Supply” (EIBS) that exists in tissues that are close to, but are not themselves, the abnormal tissue.
Abstract translation: 本发明在一个方面涉及用可能的腺瘤性和增生性息肉区分的方法，其使用以下称为“微血管供血的早期增加”（EIBS），其存在于接近但不是 自己，异常组织。
-
25.发明公开公开(公告)号：US20240175093A1
公开(公告)日：2024-05-30
申请号：US18552414
申请日：2022-03-25
Inventor： Sean PITRODA , Mitchell POSNER , Ralph WEICHSELBAUM , Mark TALAMONTI
IPC: C12Q1/6886 , C12Q1/686 , G16B25/10 , G16H50/20
CPC classification number: C12Q1/6886 , C12Q1/686 , G16B25/10 , G16H50/20 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178
Abstract: Methods, assays, and compositions for identifying molecular subtypes of metastatic cancer are disclosed. Methods include determining expression levels of genes and/or miRNAs in a sample of metastatic tissue and identifying the molecular subtype of the metastasis based on the determined expression levels using a neural network-based classifier. Methods may further include providing a prognosis and making treatment decision based on the molecular subtype of the metastasis.
-
Patent Agency Ranking
公开(公告)号：US20240150792A1
公开(公告)日：2024-05-09
申请号：US18547139
申请日：2022-02-24
Applicant: NorthShore University HealthSystem
Inventor： Prem Seth
IPC: C12N15/86 , A61K35/761 , A61K45/06 , A61P35/00 , C07K14/535 , C07K14/71
CPC classification number: C12N15/86 , A61K35/761 , A61K45/06 , A61P35/00 , C07K14/535 , C07K14/71 , C07K2319/30 , C12N2710/10032 , C12N2710/10041 , C12N2810/6018 , C12N2820/007
Abstract: The present disclosure provides an oncolytic virus comprising a nucleic acid(s) encoding a granulocyte-macrophage colony-stimulating factor (GM-CSF) and a soluble form of the TGF-B receptor-II (sTGF-BRII). The present disclosure also provides compositions comprising the oncolytic virus and treatment methods using the oncolytic virus. The treatment methods include local and/or systemic administration of the oncolytic virus for treating cancers, such as solid tumors.
-
公开(公告)号：US10517490B2
公开(公告)日：2019-12-31
申请号：US15332107
申请日：2016-10-24
Inventor： Shivraman Giri , Robert R. Edelman , Ioannis Koktzoglou , Himanshu Bhat
IPC: A61B5/026 , G01R33/563 , G01R33/56 , G01R33/483 , A61B5/00
Abstract: A method for producing an image representative of the vasculature of a subject using a MRI system includes the acquisition of a signal indicative of a subject' cardiac phase. During each heartbeat of the subject, image slices of a volume covering a region of interest (ROI) within the subject are acquired by applying a volume-selective venous suppression pulse to suppress (a) venous signal for an upper slice in the ROI; (b) venous signal for slices that are upstream for venous flow in the ROI; and (c) background signal from the upstream slices. Next, a slice-selective background suppression pulse is applied to suppress background signal of the upper slice. Following a quiescent time interval, a spectrally selective fat suppression pulse is applied to the entire volume to attenuate signal from background fat signal. Then, a simultaneous multi-slice acquisition of the upper slice and the upstream slices is performed.
-
公开(公告)号：US10353031B2
公开(公告)日：2019-07-16
申请号：US14928372
申请日：2015-10-30
Inventor： Sven Zuehlsdorff , Shivraman Giri , Robert R. Edelman
IPC: G01V3/00 , G01R33/3875 , G01R33/483 , G01R33/561 , G01R33/565
Abstract: A method of acquiring magnetic resonance imaging (MRI) data of a subject includes dividing a region of interest into a plurality of slices, and acquiring the slices using an iterative process that interleaves acquisition of shim data covering the plurality of slices with acquisition of image data covering the slices over a plurality of iterations.
-
29.发明授权公开(公告)号：US10120048B2
公开(公告)日：2018-11-06
申请号：US14788266
申请日：2015-06-30
Applicant: Northshore University HealthSystem
Inventor： Ioannis Koktzoglou , Shivraman Giri , Robert R. Edelman
IPC: G01R33/48 , G01R33/565
Abstract: Systems and methods for designing a data acquisition scheme to be used in magnetic resonance imaging (“MRI”) are provided. In particular, the systems and methods include designing efficient, or otherwise optimized, azimuthal equidistant projections for radially sampling k-space. This sampling pattern resulting from this data acquisition scheme minimizes image artifacts, including those attributable to eddy currents. The data acquisition scheme can be computed rapidly and automatically and, thus, is fit for routine use in clinical MRI systems.
-
公开(公告)号：US20180127833A1
公开(公告)日：2018-05-10
申请号：US15727924
申请日：2017-10-09
Inventor： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
IPC: C12Q1/6886 , G01N21/64 , G01N33/574 , G01N21/41 , C12Q1/6806
CPC classification number: C12Q1/6886 , C12Q1/6806 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , G01N21/41 , G01N21/64 , G01N21/6486 , G01N33/57407 , G01N33/57411 , G01N33/57419 , G01N33/57484
Abstract: The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.
-
-
-
-
-
-
-
-
-
Search Results
35
records
(took 0.017 seconds)
