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公开(公告)号：US6001067A
公开(公告)日：1999-12-14
申请号：US811473
申请日：1997-03-04
IPC分类号： G01N27/30 , A61B5/00 , A61B5/145 , A61B5/1473 , A61B5/1495 , C12Q1/00 , G01N27/327
CPC分类号： A61B5/14865 , A61B5/0004 , A61B5/14532 , A61B5/1495 , C12Q1/006
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
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公开(公告)号：US08527026B2
公开(公告)日：2013-09-03
申请号：US13411414
申请日：2012-03-02
CPC分类号： A61B5/14532 , A61B5/0031 , A61B5/1455 , A61B5/14558 , A61B5/1459 , A61B5/1486 , A61B5/14865 , A61B2562/17 , C12Q1/006
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
摘要翻译： 描述了用于确定分析物水平的装置和方法。 装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品输送到植入装置。 这些设备在传感器区域中包括独特的架构布置，可以在长时间内获得准确的数据。
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公开(公告)号：US20110253533A1
公开(公告)日：2011-10-20
申请号：US13166685
申请日：2011-06-22
CPC分类号： A61B5/14865 , A61B5/0004 , A61B5/14532 , A61B5/1495 , C12Q1/006
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
摘要翻译： 描述了用于确定分析物水平的装置和方法。 装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品递送到植入的装置。 这些设备包括传感器区域中的独特的微架构布置，允许在长时间段内获得准确的数据。
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公开(公告)号：US07899511B2
公开(公告)日：2011-03-01
申请号：US11333837
申请日：2006-01-17
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/14 , A61B5/1411 , A61B5/14514 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B2560/0223
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.
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公开(公告)号：US20100204555A1
公开(公告)日：2010-08-12
申请号：US12763013
申请日：2010-04-19
IPC分类号： A61B5/1473
CPC分类号： A61B5/14865 , A61B5/0004 , A61B5/14532 , A61B5/1495 , C12Q1/006
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
摘要翻译： 描述了用于确定分析物水平的装置和方法。 装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品递送到植入的装置。 这些设备包括传感器区域中的独特的微架构布置，允许在长时间段内获得准确的数据。
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公开(公告)号：US20080296155A1
公开(公告)日：2008-12-04
申请号：US12113724
申请日：2008-05-01
IPC分类号： C12M1/40
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/14 , A61B5/1411 , A61B5/14514 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B2560/0223
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.
摘要翻译： 本发明一般涉及用于测量宿主中分析物的系统和方法。 更具体地，本发明涉及用于经皮和皮下测量宿主中葡萄糖的系统和方法。
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公开(公告)号：US20080228051A1
公开(公告)日：2008-09-18
申请号：US12037812
申请日：2008-02-26
申请人： Mark C. Shults , James H. Brauker , Victoria Carr-Brendel , Mark A. Tapsak , Dubravka Markovic , Stuart J. Updike , Rathbun K. Rhodes
发明人： Mark C. Shults , James H. Brauker , Victoria Carr-Brendel , Mark A. Tapsak , Dubravka Markovic , Stuart J. Updike , Rathbun K. Rhodes
IPC分类号： A61B5/145
CPC分类号： A61L31/10 , A61B5/14532 , A61B5/14865 , A61B5/1495 , A61L31/14 , A61L31/146 , A61L31/16 , A61L2300/00 , B33Y80/00 , C12Q1/006
摘要： An implantable analyte-measuring device including a membrane adapted to promote vascularization and/or interfere with barrier cell layer formation. The membrane includes any combination of materials, architecture, and bioactive agents that facilitate analyte transport to provide long-term in vivo performance of the implantable analyte-measuring device.
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公开(公告)号：US07110803B2
公开(公告)日：2006-09-19
申请号：US10657843
申请日：2003-09-09
IPC分类号： A61F7/00
CPC分类号： A61B5/14865 , A61B5/14532 , C12Q1/006
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
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公开(公告)号：US4568335A
公开(公告)日：1986-02-04
申请号：US415757
申请日：1982-09-07
申请人： Stuart J. Updike , Mark C. Shults
发明人： Stuart J. Updike , Mark C. Shults
CPC分类号： B01F13/005 , A61M5/1424 , A61M5/31586 , B01F13/0052 , A61M5/31595
摘要： A device comprising a container and a threaded rotatable plunger mechanism including means for controllably advancing the plunger through the container can administer a precise dose of a drug-containing fluid subcutaneously at regular intervals. The means for controllably advancing the plunger comprises a drive tube concentrically mounted about a threaded rod operating within the container, the drive tube having ramp means at the upper end thereof, a ratchet head including a resilient member in operative communication with the upper end of the drive tube and a rotatable knob adjacent the ratchet head whereby rotation of the knob in one direction rotates the drive tube and the threaded rod to deliver the fluid through an outlet of the container.
摘要翻译： 包括容器和带螺纹的可旋转柱塞机构的装置包括用于将柱塞可控地推进通过容器的装置，可以以规则的间隔皮下投与精确剂量的含药流体。 用于可控地推进柱塞的装置包括同心地安装在操作在容器内的螺纹杆的驱动管上，驱动管在其上端具有斜坡装置，棘轮头包括弹性构件，该弹性构件与 驱动管和邻近棘轮头的可旋转旋钮，由此旋钮在一个方向上的旋转使驱动管和螺杆旋转，以将流体输送通过容器的出口。
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公开(公告)号：US3996141A
公开(公告)日：1976-12-07
申请号：US434231
申请日：1974-01-17
申请人： Stuart J. Updike
发明人： Stuart J. Updike
CPC分类号： B01D61/30 , A61M1/1629 , A61M1/1698 , B01D69/145 , A61M1/3687 , A61M2202/0225 , A61M2202/0476
摘要： A semi-permeable membrane containing a catalyst for conversion of hydrogen peroxide introduced from one side of the semi-permeable membrane to molecular oxygen which is released from the opposite side of the semi-permeable membrane. The catalyst is preferably in the form of a ruthenium oxide or sulfide and preferably in assymetrical distribution in the membrane.
摘要翻译： 一种半透膜，其包含从半透膜的一侧引入的转换过氧化氢的催化剂，其从半透膜的相对侧释放到分子氧。 催化剂优选为氧化钌或硫化物的形式，优选在膜中的不对称分布。
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