Patent search ap:("10X GENOMICS Page INC.") AND inv:"Jessica Michele Terry"

21.

发明授权
Systems and methods for quality control in single cell processing 有权

公开(公告)号：US11155881B2

公开(公告)日：2021-10-26

申请号：US16434089

申请日：2019-06-06

Applicant: 10X GENOMICS, INC.

Inventor： Zachary Bent , Paul Ryvkin , Jessica Michele Terry , Geoffrey McDermott , Meghan Leigh Flanders Frey

IPC: C12Q1/68 , C12Q1/6888 , C12Q1/682 , C12Q1/6834 , C12Q1/6848

Abstract: Provided are systems and methods for analyzing a single cell application or experiment. A set of control beads may be introduced to a biological sample and subjected to the single cell application. The control beads may be configured to mimic analytes in the biological sample, such as a cell or other analyte, and comprise one or more known sequences. The one or more known sequences may be identified to analyze the single cell application.

22.

发明申请
METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES 有权

公开(公告)号：US20210130892A1

公开(公告)日：2021-05-06

申请号：US17084481

申请日：2020-10-29

Applicant: 10X Genomics, Inc.

Inventor： Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo , Stephane Claude Boutet , Sarah Taylor , Niranjan Srinivas

IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6806

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.

23.

发明申请
TRANSCRIPTOME SEQUENCING THROUGH RANDOM LIGATION 有权

公开(公告)号：US20210047684A1

公开(公告)日：2021-02-18

申请号：US17003790

申请日：2020-08-26

Applicant: 10X GENOMICS, INC.

Inventor： Vijay Kumar Sreenivasa Gopalan , Paul Ryvkin , Zachary Bent , Jessica Michele Terry , David Jaffe , Patrick Marks , Tarjei Sigurd Mikkelsen

IPC: C12Q1/6869 , C12Q1/6806 , C12N15/10 , C12Q1/6844

Abstract: The present disclosure provides methods and systems for producing full-length sequencing information of transcriptomes from single cells or from the bulk. Random ligation and circularization of barcoded or non-barcoded complementary deoxyribonucleic molecules can be used to provide a circular template for amplification and subsequent sequencing.

24.

发明授权
Methods and systems for processing polynucleotides 有权

公开(公告)号：US10323278B2

公开(公告)日：2019-06-18

申请号：US15875899

申请日：2018-01-19

Applicant: 10X GENOMICS, INC.

Inventor： Phillip Belgrader , Zachary Bent , Tarjei Sigurd Mikkelsen , Paul Ryvkin , Jessica Michele Terry

IPC: C12Q1/68 , C12Q1/6874 , C12Q1/683 , C12Q1/6806

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

25.

发明授权
Methods and systems for processing polynucleotides 有权

公开(公告)号：US12110549B2

公开(公告)日：2024-10-08

申请号：US17822117

申请日：2022-08-24

Applicant: 10x Genomics, Inc.

Inventor： Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo , Stephane Claude Boutet , Sarah Taylor , Niranjan Srinivas

IPC: C12Q1/68 , C12Q1/6806 , C12Q1/683 , C12Q1/6874

CPC classification number: C12Q1/6874 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2537/143 , C12Q2563/179

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.

26.

发明申请
METHODS AND SYSTEMS FOR ANALYSIS OF MAJOR HISTOCOMPATABILITY COMPLEX 审中-公开

公开(公告)号：US20190367966A1

公开(公告)日：2019-12-05

申请号：US16375102

申请日：2019-04-04

Applicant: 10X Genomics, Inc.

Inventor： Kamila Belhocine , Jason Bell , Zachary Bent , Rajiv Bharadwaj , Christopher Hindson , Mohammad Rahimi Lenji , Bill Kengli Lin , Anthony Makarewicz , Geoffrey McDermott , Elliott Meer , Francesca Meschi , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Michael Schnall-Levin , Sarah Taylor , Jessica Michele Terry , Tobias Daniel Wheeler , Yifeng Yin , Xinying Zheng , Solongo Batjargal Ziraldo , Eswar Prasad Ramachandran Iyer , Luigi Jhon Alvarado Martinez

IPC: C12Q1/6806 , G01N33/53 , G01N33/58 , C12Q1/6804 , G01N33/50 , C12N15/10

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization from one or more cells. Such polynucleotide processing may be useful for a variety of applications, including characterization of major histocompatibility complex (MHC) molecules. The compositions, methods, systems, and devices disclosed herein generally describe peptides and barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing MHC molecules from one or more cells.

27.

发明授权
Methods and systems for processing polynucleotides 有权

公开(公告)号：US10480029B2

公开(公告)日：2019-11-19

申请号：US15933299

申请日：2018-03-22

Applicant: 10X GENOMICS, INC.

Inventor： Zachary Bent , Josephine Harada , Christopher Hindson , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Solongo Batjargal Ziraldo

IPC: C12Q1/68 , C12Q1/6874 , C12Q1/683 , C12Q1/6806

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

28.

发明申请
METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES 审中-公开

公开(公告)号：US20190338353A1

公开(公告)日：2019-11-07

申请号：US16426762

申请日：2019-05-30

Applicant: 10X GENOMICS, INC.

Inventor： Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo

IPC: C12Q1/6874 , C12N15/10 , C12Q1/683 , C12Q1/6806 , C12Q1/6804

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.