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21.发明授权Controlling moisture in and plasticization of bioresorbable polymer for melt processing 有权控制生物可吸收聚合物的水分和塑化，用于熔体加工公开(公告)号：US09168677B2
公开(公告)日：2015-10-27
申请号：US14311175
申请日：2014-06-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Bethany Steichen , Stephen Pacetti , Manish Gada , Thierry Glauser , Lothar Kleiner , Yunbing Wang , James Oberhauser , Ni Ding
CPC classification number: B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/1018 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006
Abstract: Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
Abstract translation: 公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。 进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。
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22.发明申请TUBE EXPANSION PROCESSES FOR SEMICRYSTALLINE POLYMERS TO MAXIMIZE FRACTURE TOUGHNESS 有权用于半结晶聚合物的管扩展方法以最大限度地减少破裂韧性公开(公告)号：US20140374963A1
公开(公告)日：2014-12-25
申请号：US14480484
申请日：2014-09-08
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , James P. Oberhauser , Thierry Glauser , David Wrolstad , Yunbing Wang
CPC classification number: B29C61/04 , B29C35/045 , B29C35/0805 , B29C71/0063 , B29C71/02 , B29C2035/0822 , B29C2071/022 , B29K2067/046 , B29K2105/258 , B29K2995/004 , B29K2995/006 , B29K2995/0089 , B29L2031/7534
Abstract: Methods for fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube and fabricating a stent from the expanded tube are disclosed. The polymer tube is disposed within a mold and may be heated with radiation. The heated tube radially expands within the mold.
Abstract translation: 公开了制造具有改进的断裂韧性的聚合物支架的方法，包括聚合物管的径向膨胀和从膨胀管制造支架。 聚合物管设置在模具内并且可以用辐射加热。 加热管在模具内径向扩张。
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公开(公告)号：US20140363563A1
公开(公告)日：2014-12-11
申请号：US14308412
申请日：2014-06-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Mikael Trollsas , Thierry Glauser , Yiwen Tang
CPC classification number: A61L31/10 , A61K38/08 , A61K38/39 , A61L27/227 , A61L27/34 , A61L27/54 , A61L29/085 , A61L31/047 , A61L31/16 , A61L2300/25 , A61L2420/02 , B05D3/007 , C07K14/001 , C08H1/00 , Y10T428/3154 , Y10T428/31909
Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
Abstract translation: 提供了包含弹性蛋白五肽嵌段的共聚物以及制备和使用该共聚物的方法。
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公开(公告)号：US20140356519A1
公开(公告)日：2014-12-04
申请号：US14308444
申请日：2014-06-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Mikael Trollsas , Thierry Glauser , Yiwen Tang
IPC: A61L31/10
CPC classification number: A61L31/10 , A61K38/08 , A61K38/39 , A61L27/227 , A61L27/34 , A61L27/54 , A61L29/085 , A61L31/047 , A61L31/16 , A61L2300/25 , A61L2420/02 , B05D3/007 , C07K14/001 , C08H1/00 , Y10T428/3154 , Y10T428/31909
Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
Abstract translation: 提供了包含弹性蛋白五肽嵌段的共聚物以及制备和使用该共聚物的方法。
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25.发明授权Tube expansion processes for semicrystalline polymers to maximize fracture toughness 有权用于半结晶聚合物的管膨胀过程以使断裂韧性最大化公开(公告)号：US08828305B2
公开(公告)日：2014-09-09
申请号：US13631061
申请日：2012-09-28
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , James P. Oberhauser , Thierry Glauser , David K. Wrolstad , Yunbing Wang
IPC: B29C49/64
CPC classification number: B29C61/04 , B29C35/045 , B29C35/0805 , B29C71/0063 , B29C71/02 , B29C2035/0822 , B29C2071/022 , B29K2067/046 , B29K2105/258 , B29K2995/004 , B29K2995/006 , B29K2995/0089 , B29L2031/7534
Abstract: Methods for fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube and fabricating a stent from the expanded tube are disclosed. The polymer tube is disposed within a mold and may be heated with radiation. The heated tube radially expands within the mold.
Abstract translation: 公开了制造具有改进的断裂韧性的聚合物支架的方法，包括聚合物管的径向膨胀和从膨胀管制造支架。 聚合物管设置在模具内并且可以用辐射加热。 加热管在模具内径向扩张。
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Patent Agency Ranking
公开(公告)号：US20140114394A1
公开(公告)日：2014-04-24
申请号：US13998204
申请日：2013-10-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： David C. Gale , Bin Huang , Timothy A. Limon , Vincent J. Gueriguian , Anthony J. Abbate , Klaus Kleine , Stephen Schaible , Jonathan P. Durcan , Thierry Glauser , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth , Yunbing Wang , Daniel Castro , David Wrolstad
IPC: A61F2/82
CPC classification number: A61F2/915 , A61F2002/9522 , A61F2210/0004 , A61F2240/001 , A61F2250/0067 , A61L31/06 , A61L31/14 , B29C35/045 , B29C49/0005 , B29C49/14 , B29C49/4823 , B29C55/24 , B29C69/001 , B29C2049/0089 , B29C2793/0009 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29K2995/006 , B29L2031/7534 , C08L67/04
Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
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公开(公告)号：US20140107761A1
公开(公告)日：2014-04-17
申请号：US13998194
申请日：2013-10-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： David C. Gale , Bin Huang , Timothy A. Limon , Vincent J. Gueriguian , Anthony J. Abbate , Klaus Kleine , Stephen Schaible , Jonathan P. Durcan , Thierry Glauser , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth , Yunbing Wang , Daniel Castro , David Wrolstad
IPC: A61F2/82
CPC classification number: A61F2/90 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61L31/06 , A61L31/14 , B29C35/045 , B29C49/0005 , B29C49/14 , B29C49/4823 , B29C55/24 , B29C69/001 , B29C2049/0089 , B29C2793/0009 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29K2995/006 , B29L2031/7534 , C08L67/04
Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
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公开(公告)号：US20130287833A1
公开(公告)日：2013-10-31
申请号：US13923559
申请日：2013-06-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Thierry Glauser , Stephen D. Pacetti , Paul M. Consigny
CPC classification number: A61K33/00 , A61K45/06 , A61L29/16 , A61L31/08 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/114 , A61L2300/606
Abstract: Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided.
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公开(公告)号：US20180154051A1
公开(公告)日：2018-06-07
申请号：US15797218
申请日：2017-10-30
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Fuh-Wei Tang , Lothar W. Kleiner , Thierry Glauser , Yiwen Tang , Wouter E. Roorda , Stephen D. Pacetti , Gina Zhang , Yung-Ming Chen , Andrew F. McNiven , Sean A. McNiven , Brandon J. Yoe
CPC classification number: A61L31/10 , A61L27/40 , A61L27/44 , A61L27/50 , A61L27/54 , A61L31/12 , A61L31/14 , A61L31/16 , A61L2300/00
Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix that include designing and creating a predetermined initial morphology (IM) profile in a polymeric matrix. The teachings indicate, inter alia, that control over the release rate of agents can provide for an improved control over the administration of agents as well as have an effect upon the mechanical integrity and absorption rate of the polymeric matrix.
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公开(公告)号：US09821091B2
公开(公告)日：2017-11-21
申请号：US13953656
申请日：2013-07-29
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F. A. Hossainy , Fuh-Wei Tang , Lothar W. Kleiner , Thierry Glauser , Yiwen Tang , Wouter E. Roorda , Stephen D. Pacetti , Gina Zhang , Yung-Ming Chen , Andrew F. McNiven , Sean A. McNiven , Brandon J. Yoe
CPC classification number: A61L31/10 , A61L27/40 , A61L27/44 , A61L27/50 , A61L27/54 , A61L31/12 , A61L31/14 , A61L31/16 , A61L2300/00
Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix. The methods relate to the application of pressure, and optionally, in combination with heat, to a polymeric coating.
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