公开(公告)号：US20080166288A1

公开(公告)日：2008-07-10

申请号：US11619866

申请日：2007-01-04

申请人： Zhenhua Zhou ,  Zhihua Wu ,  Bing Zhou

发明人： Zhenhua Zhou ,  Zhihua Wu ,  Bing Zhou

IPC分类号： C01B15/029 ,  B01J21/10 ,  B01J21/04 ,  B01J21/06 ,  B01J21/08 ,  B01J21/12 ,  B01J21/16 ,  B01J29/06 ,  B01J31/06 ,  B01J31/02

CPC分类号： C01B15/029 ,  B01J21/08 ,  B01J23/44 ,  B01J35/0013 ,  B01J35/023 ,  B01J37/0207 ,  B01J37/0211 ,  B01J37/0213 ,  B01J37/10 ,  B01J37/18

摘要： Supported catalysts are manufactured from a pretreated porous support material and a nanocatalyst solution of catalyst nanoparticles. The porous support material is pre-treated with a gaseous solvent (e.g., steam or alcohol) to protect the support material from cracking during impregnation of the nanocatalyst solution. The supported catalysts have more uniform size, lower attrition of metals during manufacturing and use, and improved distributions of metal loading compared to catalysts manufactured using known techniques. Hydrogen peroxide manufactured from such catalysts is less likely to be contaminated with catalyst metal.

摘要翻译： 负载催化剂由预处理的多孔载体材料和催化剂纳米颗粒的纳米催化剂溶液制成。 多孔支撑材料用气态溶剂（例如蒸汽或醇）进行预处理，以保护支撑材料在浸渍纳米催化剂溶液期间不会开裂。 负载催化剂在制造和使用过程中具有更均匀的尺寸，更低的金属磨损，以及与使用已知技术制造的催化剂相比，金属负载的分布改善。 由这种催化剂制造的过氧化氢不太可能被催化剂金属污染。

公开(公告)号：US07396795B2

公开(公告)日：2008-07-08

申请号：US11216442

申请日：2005-08-31

申请人： Clementine Reyes ,  Bing Zhou

发明人： Clementine Reyes ,  Bing Zhou

IPC分类号： B01J31/00 ,  B01J23/02 ,  B01J23/00 ,  B01J23/40 ,  B01J23/42

CPC分类号： B01J35/0013 ,  B01J21/18 ,  B01J23/44 ,  B01J37/0207 ,  B82Y30/00 ,  B82Y40/00 ,  Y10S502/506 ,  Y10S502/51

摘要： Highly dispersed supported catalyst nanoparticles are manufactured at temperatures below about 95° C. The catalyst nanoparticles are formed on a support using an organic anchoring agent. The anchoring agent molecules include at least two functional groups. One functional group is selected to bond with the catalyst atoms and the other functional group is selected to bond with the support material. The anchoring agent and its interaction with the support provide a template for the catalyst atoms. The catalyst nanoparticles are manufactured by treating the support material with a solution of the anchoring agent. A solution of the catalyst atoms is reacted with the anchoring agent molecules to form an intermediate supported catalyst. The supported intermediate catalyst is dried by heating at a temperature less than about 95° C. In an alternative embodiment, the catalyst atoms are reacted with the anchoring agent molecules prior to treating the support material with the anchoring agent.

摘要翻译： 在低于约95℃的温度下制备高度分散的负载型催化剂纳米颗粒。使用有机锚固剂在载体上形成催化剂纳米颗粒。 锚定剂分子包括至少两个官能团。 选择一个官能团与催化剂原子键合，并选择另一个官能团与载体材料结合。 锚固剂及其与载体的相互作用提供了催化剂原子的模板。 通过用锚固剂的溶液处理载体材料来制造催化剂纳米颗粒。 使催化剂原子的溶液与锚固剂分子反应形成中间载体催化剂。 负载的中间催化剂通过在低于约95℃的温度下加热而干燥。在替代实施方案中，在用锚定剂处理载体材料之前，催化剂原子与锚定剂分子反应。

公开(公告)号：US20080076660A1

公开(公告)日：2008-03-27

申请号：US11534595

申请日：2006-09-22

申请人： Clementine Reyes ,  Martin Fransson ,  Horacio Trevifio ,  Bing Zhou

发明人： Clementine Reyes ,  Martin Fransson ,  Horacio Trevifio ,  Bing Zhou

IPC分类号： B01J29/06 ,  B01J31/00 ,  B01J21/18 ,  B01J21/00

CPC分类号： B01J23/755 ,  B01J21/04 ,  B01J23/883 ,  B01J35/0013 ,  B01J35/0053 ,  B01J35/006 ,  B01J35/0066 ,  B01J37/0203

摘要： Supported nickel catalyst having high nickel loading and dispersion are manufactured using a dispersing agent. The dispersing agent molecules include at least one functional group that bonds with the nickel atoms and influences nanoparticle formation. The support material is loaded with at least about 5% nickel, more preferably at least about 8%, and most preferably at least about 12% by weight of the total catalyst. Catalysts manufactured using the organic dispersing agents and loaded with the foregoing amounts of nickel have metal dispersions greater than about 5% as measured by hydrogen adsorption, more preferably greater than about 10%, and most preferably greater than about 15%.

摘要翻译： 使用分散剂制造具有高镍负载和分散性的负载型镍催化剂。 分散剂分子包括至少一个与镍原子键合并影响纳米颗粒形成的官能团。 载体材料装载有总催化剂重量的至少约5％镍，更优选至少约8％，最优选至少约12％。 使用有机分散剂制造并加载上述量的镍的催化剂通过氢吸附测量的金属分散度大于约5％，更优选大于约10％，最优选大于约15％。

公开(公告)号：US20070265162A1

公开(公告)日：2007-11-15

申请号：US11539042

申请日：2006-10-05

申请人： Cheng Zhang ,  Martin Fransson ,  Changkun Liu ,  Bing Zhou

发明人： Cheng Zhang ,  Martin Fransson ,  Changkun Liu ,  Bing Zhou

IPC分类号： D01F9/12 ,  B01J23/02

CPC分类号： H01M4/96 ,  B01J21/18 ,  B01J21/185 ,  B01J23/40 ,  B01J23/74 ,  B01J37/084 ,  B82Y30/00 ,  C01B32/05 ,  H01M4/9083

摘要： Methods for manufacturing carbon nanostructures include: 1) forming a plurality of catalytic templating particles using a plurality of dispersing agent molecules; 2) forming an intermediate carbon nanostructure by polymerizing a carbon precursor in the presence of the plurality of templating nanoparticles; 3) carbonizing the intermediate carbon nanostructure to form a composite nanostructure; and 4) removing the templating nanoparticles from the composite nanostructure to yield the carbon nanostructures. The carbon nanostructures are well-suited for use as a catalyst support. The carbon nanostructures exhibit high surface area, high porosity, and high graphitization. Carbon nanostructures according to the invention can be used as a substitute for more expensive and likely more fragile carbon nanotubes.

摘要翻译： 制造碳纳米结构的方法包括：1）使用多个分散剂分子形成多个催化模板颗粒; 2）通过在多个模板纳米颗粒的存在下聚合碳前体形成中间碳纳米结构; 3）碳化中间碳纳米结构以形成复合纳米结构; 和4）从复合纳米结构中去除模板纳米颗粒以产生碳纳米结构。 碳纳米结构非常适合用作催化剂载体。 碳纳米结构表现出高的表面积，高孔隙率和高石墨化。 根据本发明的碳纳米结构可用作更昂贵且可能更脆弱的碳纳米管的替代物。

公开(公告)号：US20070219084A1

公开(公告)日：2007-09-20

申请号：US11378877

申请日：2006-03-17

申请人： Sukesh Parasher ,  Cheng Zhang ,  Michael Rueter ,  Bing Zhou

发明人： Sukesh Parasher ,  Cheng Zhang ,  Michael Rueter ,  Bing Zhou

IPC分类号： B01J31/00 ,  B01F3/12 ,  B01F17/00

CPC分类号： B01J35/0013 ,  B01J13/0043 ,  B01J23/40 ,  B01J37/18 ,  B82Y30/00

摘要： Metal-containing colloids are manufactured by reacting a plurality of metal ions and a plurality of organic agent molecules to form metal complexes in a mixture having a pH greater than about 4.25. The metal complexes are reduced for at least 0.5 hour to form stable colloidal nanoparticles. The extended reduction time improves the stability of the colloidal particles as compared to shorter reduction times. The stability of the colloidal particles allows for colloids with higher concentrations of metal to be formed. The concentration of metal in the colloid is preferably at least about 150 ppm by weight.

摘要翻译： 含金属胶体通过使多种金属离子和多种有机试剂分子反应，在pH大于约4.25的混合物中形成金属络合物来制造。 将金属络合物还原至少0.5小时以形成稳定的胶体纳米颗粒。 与较短的还原时间相比，延长的还原时间提高了胶体颗粒的稳定性。 胶体颗粒的稳定性允许形成具有较高浓度金属的胶体。 胶体中金属的浓度优选为至少约150ppm重量。

公开(公告)号：US20070180760A1

公开(公告)日：2007-08-09

申请号：US11351661

申请日：2006-02-09

申请人： Bing Zhou ,  Zhihua Wu ,  Martin Fransson

发明人： Bing Zhou ,  Zhihua Wu ,  Martin Fransson

IPC分类号： C10L1/12

CPC分类号： C10L10/02 ,  B01J23/745 ,  B01J35/0013 ,  B01J35/006 ,  B01J37/08 ,  C10L1/10 ,  C10L1/1208 ,  C10L1/1233 ,  C10L1/125 ,  C10L1/1824 ,  C10L1/1826 ,  C10L1/1855 ,  C10L1/1857 ,  C10L1/1881 ,  C10L1/1883 ,  C10L1/1985 ,  C10L1/2222 ,  C10L1/2225 ,  C10L1/2406 ,  C10L1/2418 ,  C10L1/2437 ,  C10L5/361 ,  C10L9/10 ,  C10L10/04

摘要： Organically complexed nanocatalyst compositions are applied to or mixed with a carbon-containing fuel (e.g., tobacco, coal, briquetted charcoal, biomass, or a liquid hydrocarbon like fuel oils or gasoline) in order to enhance combustion properties of the fuel. Nanocatalyst compositions can be applied to or mixed with a solid fuel substrate in order to reduce the amount of CO, hydrocarbons, and soot produced by the fuel during combustion. In addition, coal can be treated with inventive nanocatalyst compositions to reduce the amount of NOx produced during combustion (e.g., by removing coal nitrogen in a low oxygen pre-combustion zone of a low NOx burner). The nanocatalyst compositions include nanocatalyst particles made using a dispersing agent. At least a portion of the nanoparticles is crystalline with a spacing between crystal planes greater than about 0.28 nm. The nanocatalyst particles can be activated by heating to a temperature greater than about 75° C., more preferably greater than about 150° C. and most preferably greater than about 250° C.

摘要翻译： 将有机络合的纳米催化剂组合物施用于含碳燃料（例如烟草，煤，压块炭，生物质或液体烃如燃料油或汽油）或与其混合，以增强燃料的燃烧性能。 纳米催化剂组合物可以施加到固体燃料基质上或与固体燃料基质混合，以便减少在燃烧过程中由燃料产生的CO，烃和烟炱的量。 此外，煤可以用本发明的纳米催化剂组合物处理以减少在燃烧期间产生的NO x的量（例如，通过在低NOx燃烧器的低氧预燃烧区中除去煤氮）。 纳米催化剂组合物包括使用分散剂制备的纳米催化剂颗粒。 纳米颗粒的至少一部分是结晶的，晶面之间的间隔大于约0.28nm。 纳米催化剂颗粒可以通过加热至大于约75℃，更优选大于约150℃，最优选大于约250℃的温度来活化。

公开(公告)号：US20070049488A1

公开(公告)日：2007-03-01

申请号：US11216442

申请日：2005-08-31

申请人： Clementine Reyes ,  Bing Zhou

发明人： Clementine Reyes ,  Bing Zhou

IPC分类号： B01J31/00 ,  B01J23/00

CPC分类号： B01J35/0013 ,  B01J21/18 ,  B01J23/44 ,  B01J37/0207 ,  B82Y30/00 ,  B82Y40/00 ,  Y10S502/506 ,  Y10S502/51

摘要： Highly dispersed supported catalyst nanoparticles are manufactured at temperatures below about 95° C. The catalyst nanoparticles are formed on a support using an organic anchoring agent. The anchoring agent molecules include at least two functional groups. One functional group is selected to bond with the catalyst atoms and the other functional group is selected to bond with the support material. The anchoring agent and its interaction with the support provide a template for the catalyst atoms. The catalyst nanoparticles are manufactured by treating the support material with a solution of the anchoring agent. A solution of the catalyst atoms is reacted with the anchoring agent molecules to form an intermediate supported catalyst. The supported intermediate catalyst is dried by heating at a temperature less than about 95° C. In an alternative embodiment, the catalyst atoms are reacted with the anchoring agent molecules prior to treating the support material with the anchoring agent.

摘要翻译： 在低于约95℃的温度下制备高度分散的负载型催化剂纳米颗粒。使用有机锚固剂在载体上形成催化剂纳米颗粒。 锚定剂分子包括至少两个官能团。 选择一个官能团与催化剂原子键合，并选择另一个官能团与载体材料结合。 锚固剂及其与载体的相互作用提供了催化剂原子的模板。 通过用锚固剂的溶液处理载体材料来制造催化剂纳米颗粒。 使催化剂原子的溶液与锚固剂分子反应形成中间载体催化剂。 负载的中间催化剂通过在低于约95℃的温度下加热而干燥。在替代实施方案中，在用锚定剂处理载体材料之前，催化剂原子与锚定剂分子反应。

公开(公告)号：US07144565B2

公开(公告)日：2006-12-05

申请号：US10897493

申请日：2004-07-23

申请人： Michael Rueter ,  Bing Zhou ,  Sukesh Parasher

发明人： Michael Rueter ,  Bing Zhou ,  Sukesh Parasher

IPC分类号： C01B15/029

CPC分类号： C01B15/029

摘要： A process is disclosed for the direct catalytic production of aqueous solutions of hydrogen peroxide from hydrogen and oxygen in the presence of a small amount of one or more water soluble organic additives (about 0.1–10% by weight). Suitable catalysts include nanometer-sized noble metal catalytic crystal particles. The catalyst particles preferably have a controlled surface coordination number of 2 to increase the selectivity of hydrogen peroxide production. The water soluble additive(s) increases catalytic activity causing significant increases in the apparent first order reaction rate constant for the direct production of aqueous hydrogen peroxide.

摘要翻译： 公开了一种在少量一种或多种水溶性有机添加剂（约0.1-10重量％）存在下从氢气和氧气直接催化生产过氧化氢水溶液的方法。 合适的催化剂包括纳米级的贵金属催化晶体颗粒。 催化剂颗粒优选具有受控的表面配位数2，以增加过氧化氢生产的选择性。 水溶性添加剂增加催化活性，导致直接生产过氧化氢水溶液的表观一级反应速率常数显着增加。

公开(公告)号：US07078485B2

公开(公告)日：2006-07-18

申请号：US10313638

申请日：2002-12-05

申请人： Yongzhang Luo ,  Bing Zhou ,  Zhuobing Zhang

发明人： Yongzhang Luo ,  Bing Zhou ,  Zhuobing Zhang

IPC分类号： C07K1/00 ,  A61K61/00 ,  C12P21/06

CPC分类号： C07K14/78 ,  A61K38/00 ,  C07K2319/21

摘要： The invention relates to endostatin protein, in particular, to N-terminal modified recombinant human endostatin (rhEndostatin) proteins which have an additional metal chelating peptide sequence at the N-terminal, the preparation thereof, and methods of modifying the rhEndostatin to improve its stability in vivo and in vitro, and its biological activity. The invention further related to the resulting N-terminal modified rhEndostatin protein, a pharmaceutical composition containing the same, and use of said modified rhEndostatin or its pharmaceutical composition in treating the angiogenesis-related diseases, especially angiogenesis-dependent tumors.

摘要翻译： 本发明涉及内皮抑素蛋白，特别涉及在N-末端具有额外的金属螯合肽序列的N-末端修饰的重组人内皮抑素（rhEndostatin）蛋白及其制备方法，以及修饰rhEndostatin以改善其稳定性的方法 体内和体外，及其生物活性。 本发明进一步涉及所得N-末端修饰的rhEndostatin蛋白，含有该组合物的药物组合物，以及所述修饰的rhEndostatin或其药物组合物在治疗血管发生相关疾病尤其是血管生成依赖性肿瘤中的用途。

公开(公告)号：US07011807B2

公开(公告)日：2006-03-14

申请号：US10618808

申请日：2003-07-14

申请人： Bing Zhou ,  Michael Rueter ,  Sukesh Parasher

发明人： Bing Zhou ,  Michael Rueter ,  Sukesh Parasher

IPC分类号： C01B15/029 ,  C07D301/12 ,  C07D301/03 ,  C07D301/04 ,  C10G45/44

CPC分类号： H01M4/926 ,  H01M4/921

摘要： Supported reactive catalysts having a controlled coordination structure and methods for their production are disclosed. The supported catalysts of the present invention are useful for the preparation of hydrogen peroxide with high selectivity in addition to other chemical conversion reactions. The supported catalyst comprises catalyst particles having top or outer layer of atoms in which at least a portion of the atoms exhibit a controlled coordination number of 2. The catalyst and methods may be used for the concurrent in situ and ex situ conversion of organic compounds. In addition, a process is provided for catalytically producing hydrogen peroxide from hydrogen and oxygen feeds by contacting them with the catalysts of the invention and a suitable organic liquid solvent having a Solvent Selection Parameter (SSP) between 0.14×10−4 and 5.0×10−4.

摘要翻译： 公开了具有受控配位结构的负载型反应催化剂及其制备方法。 除了其它化学转化反应之外，本发明的负载型催化剂可用于制备具有高选择性的过氧化氢。 载体催化剂包含具有顶部或外层原子的催化剂颗粒，其中至少一部分原子表现出受控的配位数2.催化剂和方法可用于有机化合物的原位和非原位转化。 此外，提供了一种通过使它们与本发明的催化剂接触的氢气和氧气进料催化产生过氧化氢的方法以及溶剂选择参数（SSP）在0.14×10 -4之间的合适的有机液体溶剂， SUP>和5.0×10 -4。