中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

35 records (took 0.021 seconds)

    PROCESS FOR MANUFACTURING LITHIUM CARBOXYMETHYL CELLULOSE
    21.
    发明申请
    PROCESS FOR MANUFACTURING LITHIUM CARBOXYMETHYL CELLULOSE 有权
    制备碳酸羟乙基纤维素的方法

    公开(公告)号：US20160102153A1

    公开(公告)日：2016-04-14

    申请号：US14781322

    申请日：2014-05-28

    Applicant: DOW GLOBAL TECHNOLOGIES LLC

    Inventor： Alexandra Hild ,  Hans-Juergen Juhl ,  Roland Adden

    IPC: C08B11/12

    CPC classification number: C08B11/12 ,  C08B15/00

    Abstract: Prepare lithium carboxymethyl cellulose by treating sodium carboxymethyl cellulose with a weak acid to form an acid from of carboxymethyl cellulose and then treating the acid form of the carboxymethyl cellulose with lithium chloride.

    Abstract translation: 通过用弱酸处理羧甲基纤维素钠，由羧甲基纤维素形成酸，然后用氯化锂处理酸形式的羧甲基纤维素，制备羧甲基纤维素钠。

    COMPOSITION FOR APPLICATION TO A MUCOSA COMPRISING A HYDROXYALKYL METHYLCELLULOSE
    23.
    发明申请
    COMPOSITION FOR APPLICATION TO A MUCOSA COMPRISING A HYDROXYALKYL METHYLCELLULOSE 审中-公开
    用于包含羟基甲基纤维素的粘蛋白的组合物

    公开(公告)号：US20160120990A1

    公开(公告)日：2016-05-05

    申请号：US14888119

    申请日：2014-07-16

    Applicant: DOW GLOBAL TECHNOLOGIES LLC

    Inventor： Jaime L. Curtis-Fisk ,  Susan L. Jordan ,  True L. Rogers ,  Robert B. Appell ,  Matthias Knarr ,  Roland Adden

    IPC: A61K47/38 ,  A61K31/167 ,  A61K9/00 ,  A61K47/02

    CPC classification number: A61K47/38 ,  A61K9/0043 ,  A61K9/08 ,  A61K31/167 ,  A61K47/02

    Abstract: A composition designed for application to a mucosa comprises a tonicity-adjusting agent, a hydroxyalkyl methylcellulose and a liquid diluent, wherein the hydroxyalkyl methylcellulose has a DS of from 1.6 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, and at least 55 weight percent of the liquid diluent is water. When the composition comprises additionally a physiologically active agent, the composition may be used for transmucosal administration of the physiologically active agent to an individual.

    Abstract translation: 设计用于粘膜的组合物包括张力调节剂，羟烷基甲基纤维素和液体稀释剂，其中羟烷基甲基纤维素的DS为1.6至2.7，MS为0.40至1.30，其中DS为 甲氧基和MS的取代是羟基烷氧基的摩尔取代，至少55重量％的液体稀释剂是水。 当该组合物另外包含生理活性剂时，该组合物可以用于生理活性剂向个体的经粘膜施用。

    WATER-SOLUBLE POLYSACCHARIDES OF IMPROVED PALATABILITY
    24.
    发明申请
    WATER-SOLUBLE POLYSACCHARIDES OF IMPROVED PALATABILITY 审中-公开
    改进的可溶性水溶性多糖

    公开(公告)号：US20160021916A1

    公开(公告)日：2016-01-28

    申请号：US14771678

    申请日：2014-04-08

    Applicant: Dow Global Technologies LLC

    Inventor： Puspendu Deo ,  Kathryn Brown ,  Paul J. Sheskey ,  Jorg Theuerkauf ,  Roland Adden

    IPC: A23L1/22 ,  A23L1/308 ,  A23L1/226

    CPC classification number: A23L27/88 ,  A23L27/2052 ,  A23L27/72 ,  A23L33/21 ,  A23L33/24 ,  A23V2002/00 ,  C09D101/28

    Abstract: The palatability of a non-starch water-soluble polysaccharide (A) can be improved by at least partially coating the non-starch water-soluble polysaccharide (A) with a methylcellulose (B) having anhydroglucose units joined by 1-4 linkages wherein hydroxy groups of anhydroglucose units are substituted with methyl groups such that s23/s26 is 0.36 or less, wherein s23 is the molar fraction of anhydroglucose units wherein only the two hydroxy groups in the 2- and 3-positions of the anhydroglucose unit are substituted with methyl groups and wherein s26 is the molar fraction of anhydroglucose units wherein only the two hydroxy groups in the 2- and 6-positions of the anhydroglucose unit are substituted with methyl groups, with the proviso that the non-starch water-soluble polysaccharide (A) is different from said methylcellulose (B).

    Abstract translation: 非淀粉水溶性多糖（A）的适口性可以通过用具有通过1-4键连接的脱水葡萄糖单元的甲基纤维素（B）至少部分地涂覆非淀粉水溶性多糖（A）来改善，其中羟基 脱水葡萄糖单元的基团被甲基取代，使得s23 / s26为0.36以下，其中s23是脱水葡萄糖单元的摩尔分数，其中脱水葡萄糖单元的2-和3-位上的两个羟基仅被甲基 基团，其中s26是脱水葡萄糖单元的摩尔分数，其中只有脱水葡萄糖单元的2位和6位的两个羟基被甲基取代，条件是非淀粉水溶性多糖（A） 与所述甲基纤维素（B）不同。

    PROCESS FOR PREPARING AN AQUEOUS SOLUTION OF SACCHARIDES AND METHYLCELLULOSE
    25.
    发明申请
    PROCESS FOR PREPARING AN AQUEOUS SOLUTION OF SACCHARIDES AND METHYLCELLULOSE 有权
    制备香精和甲基纤维素的水溶液的方法

    公开(公告)号：US20160015058A1

    公开(公告)日：2016-01-21

    申请号：US14771932

    申请日：2014-04-08

    Applicant: DOW GLOBAL TECHNOLOGIES LLC

    Inventor： Puspendu Deo ,  Roland Adden ,  Matthias Knarr ,  Robert L. Sammler ,  Kathryn Brown

    IPC: A23L1/0534 ,  A23L1/308 ,  A61K31/717 ,  A23L1/29

    CPC classification number: A23L33/24 ,  A23L29/262 ,  A23L33/30 ,  A23V2002/00 ,  A61K31/717

    Abstract: An aqueous solution comprising (a) one or more mono-, di- and/or oligosaccharides and (b) a methylcellulose, wherein the methylcellulose has anhydroglucose units joined by 1-4 linkages wherein hydroxy groups of anhydroglucose units are substituted with methyl groups such that s23/s26 is 0.36 or less, is produced by i) mixing the methylcellulose with an aqueous liquid comprising one or more mono-, di- and/or oligosaccharides at a shear rate of at least 1000 s−1 or ii) mixing one or more mono-, di- and/or oligosaccharides with the methylcellulose and/or an aqueous liquid before, simultaneously with or after mixing the methylcellulose with the aqueous liquid at a shear rate of at least 1000 s−1.

    Abstract translation: 一种水溶液，其包含（a）一种或多种单糖，二糖和/或寡糖和（b）甲基纤维素，其中所述甲基纤维素具有通过1-4键连接的脱水葡萄糖单元，其中脱水葡萄糖单元的羟基被甲基取代， s23 / s26为0.36以下，通过i）以至少1000s -1的剪切速率将甲基纤维素与包含一种或多种单糖，二糖和/或寡糖的水性液体混合，或ii）将一 或更多的单 - ，二 - 和/或寡糖与甲基纤维素和/或水性液体在混合甲基纤维素与水性液体之前，同时或之后以至少1000s -1的剪切速率混合。

    MELT-EXTRUDED COMPOSITION COMPRISING A CELLULOSE ETHER
    27.
    发明申请
    MELT-EXTRUDED COMPOSITION COMPRISING A CELLULOSE ETHER 有权
    包含纤维素醚的熔融挤出组合物

    公开(公告)号：US20150057356A1

    公开(公告)日：2015-02-26

    申请号：US14389838

    申请日：2013-04-08

    Applicant: DOW GLOBAL TECHNOLOGIES LLC

    Inventor： Nicholas S. Grasman ,  True L. Rogers ,  Oliver Petermann ,  Meinolf Brackhagen ,  Roland Adden

    IPC: A61K47/38 ,  B29C47/00 ,  A61K9/20 ,  A61K31/192

    CPC classification number: A61K47/38 ,  A61K9/1652 ,  A61K9/2095 ,  A61K31/192 ,  B29C47/004 ,  B29C47/0066 ,  B29C2793/009 ,  B29K2001/08 ,  B29K2105/0035 ,  C08B11/193 ,  C08L1/28 ,  C08L1/284

    Abstract: A melt-extruded polymer composition comprising a) at least one cellulose ether, b) one or more active ingredients and c) one or more optional additives, wherein said at least one cellulose ether has an MS (hydroxyalkyl) of 0.05 to 0.55 and hydroxyl groups of anhydroglucose units are substituted with methyl groups such that [s23/s26−0.2*MS(hydroxyalkyl)] is 0.32 or less, wherein s23 is the molar fraction of anhydroglucose units wherein only the two hydroxyl groups in the 2- and 3-positions of the anhydroglucose unit are substituted with a methyl group and wherein s26 is the molar fraction of anhydroglucose units wherein only the two hydroxyl groups in the 2- and 6-positions of the anhydroglucose unit are substituted with a methyl group.

    Abstract translation: 一种熔融挤出的聚合物组合物，其包含a）至少一种纤维素醚，b）一种或多种活性成分和c）一种或多种任选的添加剂，其中所述至少一种纤维素醚具有0.05至0.55的MS（羟烷基）和羟基 脱水葡萄糖单元的基团被甲基取代，使得[s23 / s26-0.2 * MS（羟烷基）]为0.32以下，其中s23是脱水葡萄糖单元的摩尔分数，其中只有2位和3位的两个羟基， 脱水葡萄糖单元的位置被甲基取代，其中s26是脱水葡萄糖单元的摩尔分数，其中脱水葡萄糖单元的2-和6-位上的两个羟基仅被甲基取代。

    Dispersion comprising an esterified cellulose ether
    28.
    发明授权
    Dispersion comprising an esterified cellulose ether 有权

    公开(公告)号：US10383944B2

    公开(公告)日：2019-08-20

    申请号：US15129505

    申请日：2015-03-03

    Applicant: Dow Global Technologies LLC

    Inventor： Neal J. Fetner ,  David L. Malotky ,  Jin Zhao ,  Matthias Knarr ,  Michael J. Devon ,  Roland Adden

    IPC: A61K9/28 ,  A61K47/38 ,  A61K9/48 ,  C08B13/00 ,  C08L1/32 ,  A61J3/07

    Abstract: An aqueous composition useful for producing capsules shells comprises a) at least one dispersed esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and b) from 0.05 to 20 percent of at least one salt of a fatty acid, based on the weight of the dispersed esterified cellulose ether, wherein the median particle size, d50, of the dispersed esterified cellulose ether particles is up to 7 micrometers, such median particle size (d50) being the size at which 50 mass percent of the particles have a smaller equivalent diameter and 50 mass percent have a larger equivalent diameter.

    Dispersion comprising a partially neutralized esterified cellulose ether
    29.
    发明授权
    Dispersion comprising a partially neutralized esterified cellulose ether 有权

    公开(公告)号：US10179110B2

    公开(公告)日：2019-01-15

    申请号：US15308792

    申请日：2015-04-28

    Applicant: Dow Global Technologies LLC

    Inventor： Jin Zhao ,  Roland Adden ,  Neal J. Fetner ,  David L. Malotky

    IPC: A61K9/48 ,  B29C41/14

    Abstract: An aqueous composition comprising at least 10 weight percent of a dispersed esterified cellulose ether, based on the total weight of the aqueous composition, wherein the esterified cellulose ether comprises (i) groups of the formula —C(O)—R—COOH or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOH, R being a divalent aliphatic or aromatic hydrocarbon group, and at least a part of the groups —C(O)—R—COOH are neutralized with an ammonium salt of carbonic acid, formic acid or acetic acid, and wherein d90 of the dispersed esterified cellulose ether particles is up to 10 micrometers, d90 being the diameter where 90 mass percent of the particles have a smaller equivalent diameter and the other 10 mass percent have a larger equivalent diameter, is useful for preparing coating dosage forms including tablets, capsules and others, or for the formation of capsules shells.

Patent Agency Ranking