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公开(公告)号:US20140288528A1
公开(公告)日:2014-09-25
申请号:US14214701
申请日:2014-03-15
Applicant: Dr. Py Institute, LLC
Inventor: Daniel Py
IPC: A61M5/32
CPC classification number: A61M5/326 , A61M2005/3247 , A61M2005/3267
Abstract: A needle assembly that has a flexible shield movable between (i) a first position, where the flexible shield is uncompressed, and (ii) a second position, where the flexible shield is compressed and an administering member located within the flexible shield, where at least one of the administering member and the flexible shield is axially movable with respect to the other of the administering member and the flexible shield in an unlocked position prior to and during usage of the needle assembly, and the at least one of the administering member and the flexible shield is no longer axially movable with respect to the other of the administering member and the flexible shield in a locked position. Prior, during and after use of the needle assembly, the needle is never exposed. After a single usage of the needle assembly, the needle is locked within the flexible shield and cannot be reused.
Abstract translation: 一种针组件,其具有可在(i)第一位置和柔性屏蔽被压缩的第一位置之间移动的柔性屏蔽件,以及(ii)柔性屏蔽件被压缩的第二位置和位于柔性屏蔽件内的施用构件, 所述给药部件和所述柔性护罩中的至少一个在所述针组件的使用之前和使用期间相对于所述给药构件和所述柔性护罩中的另一个在所述解锁位置中是可轴向移动的,并且所述给药构件和 柔性护罩不再能够相对于另一个给药构件和柔性护罩在锁定位置上可轴向移动。 在使用针组件之前和之后,针头不会暴露。 在针组件单次使用后,针被锁定在柔性屏蔽内,不能重复使用。
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公开(公告)号:US20140263147A1
公开(公告)日:2014-09-18
申请号:US14208030
申请日:2014-03-13
Applicant: Dr. Py Institute, LLC
Inventor: Daniel Py
CPC classification number: A61J1/2051 , A61J1/2096 , B65B3/003 , B65B7/161 , B65D11/04 , B65D71/502
Abstract: A device that has a device body defining an opening at one end thereof, a storage chamber within the device body for storing multiple doses of a substance therein, and a sliding stopper, sealing engageable with the device body, through which the chamber is filled. The stopper has a body and a flexible portion, which may be in the form of a plurality of flexible members, extending therefrom. The flexible portion or members are movable between first and second positions. In the first position, during filling, the portion or members are substantially laterally extending from the stopper body and engaging the opening of the device body. Accordingly, the axial position of the stopper with respect to the device body is secured during filling of the chamber therethrough. In the second position, after filling, the portion or members are substantially axially-extending from the stopper body and disengaged from the rim or opening of the device body. Accordingly, the stopper is axially slideable through the body.
Abstract translation: 一种装置,其具有在其一端限定开口的装置主体,在装置主体内用于储存多个剂量的物质的储存室,以及滑动止动件,可与装置主体接合,通过该装置主体填充该容器。 止动器具有主体和柔性部分,其可以是从其延伸的多个柔性构件的形式。 柔性部分可在第一和第二位置之间移动。 在第一位置,在填充期间,该部分或部件基本上从止动体横向延伸并与装置主体的开口接合。 因此,塞子相对于装置主体的轴向位置在腔室通过其的填充期间被固定。 在第二位置,在填充之后,部分或部件基本上从止动体轴向延伸并与装置主体的边缘或开口脱离。 因此,止动件可轴向滑动通过本体。
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公开(公告)号:US20220219843A1
公开(公告)日:2022-07-14
申请号:US17508812
申请日:2021-10-22
Applicant: Dr. Py Institute, LLC
Inventor: Daniel Py
Abstract: A needle has a hollow shaft, a tip formed at one end of the shaft, one or more ports in fluid communication with the interior of the hollow shaft, and a closure. The closure and/or the shaft is movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s).
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公开(公告)号:US20200010251A1
公开(公告)日:2020-01-09
申请号:US16572879
申请日:2019-09-17
Applicant: Dr. Py Institute LLC
Inventor: Daniel Py
Abstract: A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.
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公开(公告)号:US20190185191A1
公开(公告)日:2019-06-20
申请号:US16270172
申请日:2019-02-07
Applicant: Dr. Py Institute LLC
Inventor: Daniel Py
IPC: B65B55/04 , A61J3/00 , B65B39/12 , B65B43/42 , A61J1/20 , A61M5/00 , B65B7/16 , A61J1/14 , A61M5/178
CPC classification number: B65B55/04 , A61J1/05 , A61J1/1406 , A61J1/1425 , A61J1/201 , A61J1/2089 , A61J3/002 , A61J2200/10 , A61M5/002 , A61M5/1782 , B65B7/16 , B65B39/12 , B65B43/42
Abstract: An injection member penetrates an elastic septum of a device defining a sealed, empty, sterile chamber in fluid communication with the septum. During penetrating, an annular interface is formed between the septum and the injection member extending axially between a penetration point on an interior surface of the septum in fluid communication with the sterile chamber, and an exterior surface of the septum engaging the injection member. The injection member is de-contaminated by (i) friction between the septum and injection member at the annular interface, and (ii) elongation of the septum at the annular interface. A substance is introduced through the injection member and into the sterile chamber of the device, the injection member is then withdrawn from the septum, the septum reseals itself at the resulting penetration aperture, and the chamber is maintained sterile throughout the foregoing steps.
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公开(公告)号:US20190032831A1
公开(公告)日:2019-01-31
申请号:US15961613
申请日:2018-04-24
Applicant: DR. PY INSTITUTE LLC
Inventor: Daniel Py , Jean-Abraham Py
Abstract: An apparatus for aseptic transfer of fluid therethrough. A first portion includes a closure and a piercing member comprising a hollow shaft for flowing fluid therethrough, and at least one port in fluid communication with the interior of the hollow shaft for passage of the fluid therethrough. The closure and/or the shaft is movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). A second portion includes a pierceable septum. The first and second portions are engageable such that the piercing member pierces the pierceable septum. When the pierceable member has at least partially penetrated the pierceable septum, the closure and/or the shaft moves from the first position to the second position for aseptical transfer of fluid.
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公开(公告)号:US10017286B2
公开(公告)日:2018-07-10
申请号:US14708196
申请日:2015-05-09
Applicant: Dr. Py Institute LLC
Inventor: Daniel Py
CPC classification number: B65B43/54 , B65B3/003 , B65B3/04 , B65B39/001 , B65B39/004 , B65B39/12 , B65B51/02 , B65B51/10 , B65B55/24
Abstract: An apparatus for filling a device having a penetrable septum and a sealed chamber. The apparatus includes a filling member engageable with the penetrable septum to penetrate the septum, port(s), and a closure. The closure and filling member are movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). The filling member and/or septum is movable relative to the other between (i) a first position wherein the filling member is spaced from the septum, and (ii) a second position wherein the filling member is penetrated through the septum and in communication with the sealed chamber. A locking device is movable between (i) a locked position locking the closure and/or filling member in the first position, and (ii) an unlocked position allowing movement of the closure and/or filling member relative to the other and into the second position.
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公开(公告)号:US09902508B2
公开(公告)日:2018-02-27
申请号:US14637050
申请日:2015-03-03
Applicant: Dr. Py Institute LLC
Inventor: Daniel Py
IPC: B65B3/00 , A61J7/00 , B01F11/00 , B01F15/02 , B65D75/52 , B65D81/32 , B67D3/00 , A61J1/20 , A61J1/10
CPC classification number: B65B3/003 , A61J1/10 , A61J1/2027 , A61J1/2093 , A61J7/0053 , B01F11/0065 , B01F15/0205 , B01F15/0212 , B01F15/0223 , B65D75/527 , B65D81/3266 , B67D3/0012 , B67D3/0019 , B67D3/0061
Abstract: A device and method are provided for storing substances separately, and for mixing the substances prior to use. The device defines at least one first chamber for receiving a first substance, and at least one second chamber for receiving a second substance. A first sealing portion is located between the first and second chambers and is movable between a closed position preventing fluid communication between the chambers, and an open position permitting fluid communication between the first and second chambers for mixing the substances. First and second penetrable and resealable portions in fluid communication with the first and second chamber(s), respectively, may be used for filling by penetrating them with an injection member and introduce the substances therethrough and into the respective chamber, and resealing the injection apertures and the substances within the respective chamber.
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公开(公告)号:US09663274B2
公开(公告)日:2017-05-30
申请号:US14930896
申请日:2015-11-03
Applicant: Dr. Py Institute LLC
Inventor: Daniel Py
IPC: B65D47/24 , B65D23/02 , B65D47/32 , B05B11/00 , B29C47/00 , B29C47/06 , B29C49/04 , B29L9/00 , B29L31/00
CPC classification number: B65D47/24 , B05B11/3028 , B29C47/0021 , B29C47/0023 , B29C47/0026 , B29C47/065 , B29C47/068 , B29C49/04 , B29L2009/00 , B29L2031/7158 , B65D23/02 , B65D47/205 , B65D47/32
Abstract: A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.
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公开(公告)号:US09604740B2
公开(公告)日:2017-03-28
申请号:US14214890
申请日:2014-03-15
Applicant: Dr. Py Institute, LLC
Inventor: Daniel Py
CPC classification number: B65B55/04 , A61J1/05 , A61J1/1406 , A61J1/1425 , A61J1/201 , A61J1/2089 , A61J3/002 , A61J2200/10 , A61M5/002 , A61M5/1782 , B65B7/16 , B65B39/12 , B65B43/42
Abstract: An injection member penetrates an elastic septum of a device defining a sealed, empty, sterile chamber in fluid communication with the septum. During penetrating, an annular interface is formed between the septum and the injection member extending axially between a penetration point on an interior surface of the septum in fluid communication with the sterile chamber, and an exterior surface of the septum engaging the injection member. The injection member is de-contaminated by (i) friction between the septum and injection member at the annular interface, and (ii) elongation of the septum at the annular interface. A substance is introduced through the injection member and into the sterile chamber of the device, the injection member is then withdrawn from the septum, the septum reseals itself at the resulting penetration aperture, and the chamber is maintained sterile throughout the foregoing steps.
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