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公开(公告)号：US10179048B2
公开(公告)日：2019-01-15
申请号：US15042049
申请日：2016-02-11
Applicant: Edwards Lifesciences Corporation
Inventor： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
Abstract: Embodiments of the present disclosure provide a delivery apparatus for delivering a prosthetic heart valve to a native valve site via the human vasculature without the need for a separate introducer sheath. The delivery apparatus is particularly well-suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a stenotic aortic valve.
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公开(公告)号：US20170360560A1
公开(公告)日：2017-12-21
申请号：US15676817
申请日：2017-08-14
Applicant: Edwards Lifesciences Corporation
Inventor： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo Cayabyab , Robert Bowes
CPC classification number: A61F2/2433 , A61F2/2436 , A61F2/958 , A61F2002/9517 , A61M25/0045 , A61M25/005 , A61M25/0136 , A61M25/0662 , A61M39/0613
Abstract: An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.
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公开(公告)号：US20240374386A1
公开(公告)日：2024-11-14
申请号：US18784810
申请日：2024-07-25
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Pablo Hernan Catania , Munir Hicham Eltal , Andrew John Akagawa , Robert Bowes , Waina Michelle Chu , Nicolas Schleiger , Tam Van Nguyen , Alena Lian Sim , Thanh Huyen Tran , Rupesh Gajanan Nawalakhe , Chris J. Okos , Eric Robert Dixon , Grant Matthew Stearns , Kevin Gantz , Daniel Bobo , Aric Daniel Stone
IPC: A61F2/24
Abstract: Delivery systems and methods of delivering devices or implants are disclosed. The devices or implants can be configured as valve repair devices or treatment devices have gripping members that are openable and closable to attach the device to leaflets of a native heart valve. The delivery systems are configured to position the device or implant and open and close the gripping members of the device or implant.
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公开(公告)号：US20240091007A1
公开(公告)日：2024-03-21
申请号：US18522236
申请日：2023-11-29
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Hamid Rafi , Russell T. Joseph , Robert Bowes , Uy D. Trinh , Emil Karapetian , Gregory Bak-Boychuk
IPC: A61F2/24
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2436 , A61F2/9517 , A61F2230/0054 , A61F2250/006 , A61F2250/0063
Abstract: Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. The two elements can clamp/pinch the heart valve leaflets to hold the prosthetic heart valve in place. The pinch device can have a flexible, expandable annular frame. A combined delivery system can deliver the pinch device and prosthetic heart valve with just a single access point and aid more accurate coaxial deployment. The pinch device can be mounted near distal end of an access sheath, and a catheter for delivering the prosthetic heart valve can be passed through a lumen of the same access sheath.
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公开(公告)号：US11844692B2
公开(公告)日：2023-12-19
申请号：US17651667
申请日：2022-02-18
Applicant: Edwards Lifesciences Corporation
Inventor： Hamid Rafi , Russell T. Joseph , Robert Bowes , Uy D. Trinh , Emil Karapetian , Gregory Bak-Boychuk
IPC: A61F2/24
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2436 , A61F2/2442 , A61F2210/0014 , A61F2230/0054 , A61F2230/0063 , A61F2250/006 , A61F2250/0063
Abstract: Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. The two elements can clamp/pinch the heart valve leaflets to hold the prosthetic heart valve in place. The pinch device can have a flexible, expandable annular frame. A combined delivery system can deliver the pinch device and prosthetic heart valve with just a single access point and aid more accurate coaxial deployment. The pinch device can be mounted near distal end of an access sheath, and a catheter for delivering the prosthetic heart valve can be passed through a lumen of the same access sheath.
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Patent Agency Ranking
公开(公告)号：US11253361B2
公开(公告)日：2022-02-22
申请号：US16508625
申请日：2019-07-11
Applicant: Edwards Lifesciences Corporation
Inventor： Hamid Rafi , Russell T. Joseph , Robert Bowes , Uy D. Trinh , Emil Karapetian , Gregory Bak-Boychuk
Abstract: Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. The two elements can clamp/pinch the heart valve leaflets to hold the prosthetic heart valve in place. The pinch device can have a flexible, expandable annular frame. A combined delivery system can deliver the pinch device and prosthetic heart valve with just a single access point and aid more accurate coaxial deployment. The pinch device can be mounted near distal end of an access sheath, and a catheter for delivering the prosthetic heart valve can be passed through a lumen of the same access sheath.
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公开(公告)号：US10441419B2
公开(公告)日：2019-10-15
申请号：US16197245
申请日：2018-11-20
Applicant: Edwards Lifesciences Corporation
Inventor： Thanh Huy Le , Tri D. Tran , Ronaldo C. Cayabyab , David M. Taylor , Antonio O. Vidal , Robert Bowes
Abstract: A method of delivery a prosthetic heart valve includes inserting a delivery apparatus and a prosthetic heart valve into a patient's vasculature. The delivery apparatus includes a steerable guide catheter, a balloon catheter, and a flex indicator. The balloon catheter extends coaxially through the guide catheter, the prosthetic heart valve is mounted on a distal end portion of the balloon catheter, and the flex indicator is movably coupled to a handle of the guide catheter. The method further includes adjusting flexion of a steerable section of the guide catheter to position the prosthetic heart valve. The flex indicator moves relative to the handle of the guide catheter as the flexion of the steerable section is adjusted, and the handle comprises one or more visual indicators adjacent the flex indicator to provide visual indication of an amount of flexion of the steerable section of the guide catheter.
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公开(公告)号：US10278815B2
公开(公告)日：2019-05-07
申请号：US16017465
申请日：2018-06-25
Applicant: Edwards Lifesciences Corporation
Inventor： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
Abstract: An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.
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公开(公告)号：US20190008633A1
公开(公告)日：2019-01-10
申请号：US16130726
申请日：2018-09-13
Applicant: Edwards Lifesciences Corporation
Inventor： David M. Taylor , Philippe Marchand , Larry L. Wood , Robert Bowes
Abstract: An apparatus for delivering a prosthetic device through the vasculature of a patient includes a radially expandable member coupled to the distal end of an elongate shaft. The expandable member has an open frame configuration and an outer mounting surface for mounting the prosthetic device in a collapsed state thereon. The expandable member expands radially outwards from a first configuration to a second configuration to expand a prosthetic device mounted thereon.
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公开(公告)号：US08784480B2
公开(公告)日：2014-07-22
申请号：US13910348
申请日：2013-06-05
Applicant: Edwards Lifesciences Corporation
Inventor： David Taylor , Philippe Marchand , Larry Wood , Robert Bowes
CPC classification number: A61F2/243 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2/95 , A61F2/97 , A61F2230/0076 , A61F2250/0008 , A61F2250/0029 , A61F2250/0036 , A61F2250/0059
Abstract: An apparatus and method for delivering a prosthetic device through the vasculature of a patient includes a radially expandable member coupled to the distal end of an elongate shaft. The expandable member has an open frame configuration and an outer mounting surface for mounting the prosthetic device in a collapsed state thereon. The expandable member expands radially outwards from a first configuration to a second configuration to expand a prosthetic device mounted thereon.
Abstract translation: 用于通过患者的脉管系统递送假体装置的装置和方法包括联接到细长轴的远端的可径向扩张的构件。 可扩张构件具有开放框架构造和用于将假体装置安装在其中的折叠状态的外部安装表面。 可膨胀构件从第一构型径向向外扩展到第二构型，以扩展安装在其上的假体装置。
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