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公开(公告)号：US07073246B2
公开(公告)日：2006-07-11
申请号：US10601144
申请日：2003-06-20
IPC分类号： G01R3/00
CPC分类号： G01N33/5438 , C12Q1/001 , G01N27/3272 , H05K1/0393 , H05K3/027 , Y10T29/49007 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156
摘要： A method of making a biosensor is provided. The biosensor includes an electrically conductive material on a base and electrode patterns formed on the base, the patterns having different feature sizes. The conductive material is partially removed from the base using broad field laser ablation so that less than 90% of the conductive material remains on the base and that the electrode pattern has an edge extending between two points. A standard deviation of the edge from a line extending between two points is less than about 6 μm.
摘要翻译： 提供制造生物传感器的方法。 生物传感器包括在基底上的导电材料和形成在基底上的电极图案，图案具有不同的特征尺寸。 使用宽场激光烧蚀部分地从基底去除导电材料，使得小于90％的导电材料保留在基底上，并且电极图案具有在两个点之间延伸的边缘。 边缘与两点之间延伸的线的标准偏差小于约6um。
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公开(公告)号：US07045310B2
公开(公告)日：2006-05-16
申请号：US09999110
申请日：2001-11-01
CPC分类号： C07F15/0026 , C07K5/101 , C07K7/02 , C07K7/06 , C07K9/001 , C07K14/805 , G01N27/3277 , G01N33/532 , G01N33/536 , G01N33/58 , G01N33/723 , G01N2333/805 , G01N2458/30 , Y10S436/805 , Y10S436/806 , Y10T436/105831
摘要： Novel bipyridyl-osmium complex conjugates and their use in electrochemical assays are described. The redox reversible-osmium complexes can be prepared to exhibit unique reversible redox potentials and can thus be used in combination with other electroactive redox reversible species having redox potentials differing by at least 50 millivolts in electrochemical assays designed for use of multiple electroactive species in the same cell and in the same sample without interference between the two or more redox coupled conjugate systems.
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公开(公告)号：US5997817A
公开(公告)日：1999-12-07
申请号：US985840
申请日：1997-12-05
申请人： William F. Crismore , Nigel A. Surridge , Daniel R. McMinn , Richard J. Bodensteiner , Eric R. Diebold , R. Dale Delk , David W. Burke , Jiaxiong Jason Ho , Robert Kitchel Earl , Brian A. Heald
发明人： William F. Crismore , Nigel A. Surridge , Daniel R. McMinn , Richard J. Bodensteiner , Eric R. Diebold , R. Dale Delk , David W. Burke , Jiaxiong Jason Ho , Robert Kitchel Earl , Brian A. Heald
IPC分类号： G01N27/28 , C12M1/34 , C12Q1/00 , G01N27/00 , G01N27/02 , G01N27/30 , G01N27/327 , G01N27/416 , G01N33/487 , G01N33/543 , G01N33/66 , G01N33/48
CPC分类号： C12Q1/001 , G01N27/3272 , G01N33/5438 , Y10S435/817
摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a "fill to here" line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called "dose hesitation".
摘要翻译： 一种具有四个新特征的电化学生物传感器测试条。 测试条包括针对带样品应用端口的位置的触感的缩进。 样品应用端口通向包括测试试剂的毛细管测试室。 湿试剂包括约0.2重量％至约2重量％的聚环氧乙烷约100千道尔顿至约900千道尔顿的平均分子量，这使得干燥的试剂更具亲水性并且更坚固以进行剥离加工步骤，例如机械冲压，和 由测试用户进行机械操作。 毛细管测试室的屋顶包括透明或半透明的窗口，其作为“填充到这里”线，从而识别何时将足够的测试样品（液体样品，例如血液）添加到测试室以精确地执行 测试。 测试条还可以包括位于样品应用端口处的凹口。 缺口减少了称为“剂量犹豫”的现象。
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