公开(公告)号：US08586712B2

公开(公告)日：2013-11-19

申请号：US12748304

申请日：2010-03-26

申请人： Fang Fang ,  Lori Kohlstaedt ,  John Reno

发明人： Fang Fang ,  Lori Kohlstaedt ,  John Reno

IPC分类号： C07K16/28 ,  C12N15/13 ,  C12N15/63 ,  A61K39/395

CPC分类号： C07K16/2896 ,  A61K2039/505 ,  C07K16/2821 ,  C07K2317/24 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2319/00 ,  Y02A50/412

摘要： Humanized antibodies that bind ICAM-1 are provided. Antibodies include those selected from: SEQ ID NO:1 and 3 (HumA); SEQ ID NO:5 and 7 (HumB); SEQ ID NO:9 and 11 (HumC); SEQ ID NO:13 and 15 (HumD); SEQ ID NO:17 and 19 (HumE); SEQ ID NO:21 and 23 (HumF); SEQ ID NO:25 and 27 (HumG); SEQ ID NO:29 and 31 (HumH); and SEQ ID NO:33 and 35 (HumI). Subsequences of the humanized antibodies capable of binding an ICAM-1 epitope are also provided. Methods of inhibiting pathogen infection (e.g., HRV) of a cell employing humanized antibodies capable of binding an ICAM-1 epitope are further provided.

公开(公告)号：US08394771B1

公开(公告)日：2013-03-12

申请号：US11866960

申请日：2007-10-03

申请人： Fang Fang ,  Guang-Xiang Luo ,  Lori Allison Kohlstaedt ,  Catherine Helen Charles

发明人： Fang Fang ,  Guang-Xiang Luo ,  Lori Allison Kohlstaedt ,  Catherine Helen Charles

IPC分类号： A61K38/17 ,  C12P21/04 ,  C07K14/435

CPC分类号： C07K16/2821 ,  A61K38/00 ,  C07K14/001 ,  C07K14/4705 ,  C07K2319/00 ,  C07K2319/02 ,  C07K2319/73 ,  C12N15/62

摘要： The invention provides multimerization polypeptides capable of conferring formation of multimers when the multimerization polypeptide is linked to a molecule, such as a heterologous polypeptide sequence.

公开(公告)号：US20120249441A1

公开(公告)日：2012-10-04

申请号：US13311556

申请日：2011-12-06

申请人： YUH-WEN LEE ,  Ching-Shan Lin ,  Lichun yang ,  Fang Fang

发明人： YUH-WEN LEE ,  Ching-Shan Lin ,  Lichun yang ,  Fang Fang

IPC分类号： G06F3/041 ,  B05D5/00

CPC分类号： G06F3/044 ,  G06F2203/04103

摘要： The present invention discloses a touch panel and a method of manufacturing a touch panel, to reduce the visibility of the transparent etching line of the transparent electrodes on the touch panel. The touch panel comprises a plurality of transparent electrode disposed distantly on the transparent conductive layer and the passivation layer of a transparent substrate, where the passivation layer covering the transparent conductive layer, to make the refractive index of the passivation layer and the transparent electrodes match with each other. Oxide with high refractive index added in the passivation material is filled in the etched area of the transparent conductive layer, so that the optical refractive index of the etched area and ITO area on transparent conductive layer become closer, and the difference in refractive index curve between ITO area and etched area is reduced, therefore, the effect of making the transparent electrode pattern is achieved.

摘要翻译： 本发明公开了触摸面板和制造触摸面板的方法，以降低触摸面板上的透明电极的透明蚀刻线的可视性。 触摸面板包括多个透明电极，其设置在透明导电层上的透明电极和透明衬底的钝化层，其中钝化层覆盖透明导电层，以使钝化层和透明电极的折射率与 彼此。 在钝化材料中加入高折射率的氧化物被填充在透明导电层的蚀刻区域中，使得透明导电层上的蚀刻区域和ITO区域的光学折射率变得更接近，并且折射率之间的折射率差 ITO区域和蚀刻面积减少，因此，实现了形成透明电极图案的效果。

公开(公告)号：US08262283B2

公开(公告)日：2012-09-11

申请号：US12838104

申请日：2010-07-16

申请人： Guoxing Yang ,  David G. Anderson ,  Larry M. Youngblood ,  Fang Fang ,  Sean E. Rick ,  Larry A. Spino ,  Scott K. Berkhous

发明人： Guoxing Yang ,  David G. Anderson ,  Larry M. Youngblood ,  Fang Fang ,  Sean E. Rick ,  Larry A. Spino ,  Scott K. Berkhous

IPC分类号： G01N33/22 ,  G01N25/00

CPC分类号： G01N33/2805

摘要： A thermal oxidation tester is shown for determining thermal stability of a fluid, particularly hydrocarbons when subjected to elevated temperatures. The tendency of the heated fluid to oxidize and (1) form deposits on a surface of a heater tube and (2) form solids therein, are both measured at a given flow rate, temperature and time. The measured results are used to determine whether a fluid sample passes or fails the test. Results of measurements are recorded in a memory device on one end of the heater tube on which the deposits were made.

摘要翻译： 示出了热氧化测试仪，用于确定流体，特别是当受到升高的温度时的烃的热稳定性。 加热的流体氧化的趋势和（1）在加热器管的表面上形成沉积物，和（2）在其中形成固体，都是在给定的流速，温度和时间下测量的。 测量结果用于确定流体样品是否通过或未通过测试。 测量结果记录在其上形成沉积物的加热器管的一端上的存储器件中。

公开(公告)号：US20100166874A1

公开(公告)日：2010-07-01

申请号：US12633773

申请日：2009-12-08

申请人： Michael P. Malakhov ,  Fang Fang

发明人： Michael P. Malakhov ,  Fang Fang

IPC分类号： A61K38/43 ,  A61K9/14 ,  A61K39/00 ,  A61K38/16 ,  A61K31/7088 ,  A61K31/715 ,  A61K31/56 ,  A61K47/42 ,  A61P3/10 ,  A61P25/16 ,  A61P29/00 ,  A61P23/00 ,  A61P33/06 ,  A61P31/04 ,  A61P35/00 ,  A61P3/02

CPC分类号： A61K9/1682 ,  A61K9/0073 ,  A61K9/14 ,  A61K9/1617 ,  A61K9/1647 ,  A61K9/19 ,  A61K38/18 ,  A61K38/47 ,  A61K38/57 ,  C12Y302/01018 ,  Y02A50/385 ,  Y02A50/387 ,  Y02A50/393 ,  Y02A50/401 ,  Y02A50/402 ,  Y02A50/411 ,  Y02A50/469 ,  Y02A50/47 ,  Y02A50/471 ,  Y02A50/478 ,  Y02A50/48 ,  Y02A50/483 ,  Y02A50/491 ,  Y10T428/2982

摘要： Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions.

摘要翻译： 通过使蛋白质或其他高分子的水溶液与有机溶剂和抗衡离子接触并冷却溶液来制备微球体。 微球可用于制备具有限定尺寸的药物。

公开(公告)号：US20050004020A1

公开(公告)日：2005-01-06

申请号：US10718986

申请日：2003-11-21

申请人： Mang Yu ,  Fang Fang

发明人： Mang Yu ,  Fang Fang

IPC分类号： A61K20060101 ,  A61K38/16 ,  A61K38/17 ,  A61K38/47 ,  A61K38/48 ,  A61K38/55 ,  A61K38/56 ,  A61K38/57 ,  A61K39/00 ,  A61K47/48

CPC分类号： B82Y5/00 ,  A61K38/47 ,  A61K38/57

摘要： The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of the target cell by a pathogen, such as a virus. Preferred target cells are epithelial cells. The invention provides compositions and methods for preventing viral diseases, such as influenza, using compounds having anchoring domains that can bind target cells linked to enzymatic activities that can act extracellularly to interfere with viral infection of target cells. The invention also provides compositions and methods for preventing viral diseases such as influenza using compounds having anchoring domains that can bind target cells linked to protease inhibitors that can act extracellularly to interfere with viral infection of target cells.

摘要翻译： 本发明提供了用于预防和治疗病原体感染的新的组合物和方法。 特别地，本发明提供具有将化合物锚定在靶细胞表面的锚定结构域的化合物，以及可以在细胞外作用以防止病原体如病毒感染靶细胞的治疗结构域。 优选的靶细胞是上皮细胞。 本发明提供了用于预防病毒性疾病（例如流行性感冒）的组合物和方法，使用具有锚定结构域的化合物，所述化合物具有可结合与细胞外作用以干扰靶细胞的病毒感染的酶活性连接的靶细胞。 本发明还提供了用于使用具有锚定结构域的化合物来预防病毒性疾病例如流感的组合物和方法，所述化合物具有可以结合与蛋白酶抑制剂连接的靶细胞，其可以在细胞外作用以干扰靶细胞的病毒感染。

公开(公告)号：USD911039S1

公开(公告)日：2021-02-23

申请号：US29706966

申请日：2019-09-25

申请人： Edward Eng ,  Fang Fang

设计人： Edward Eng ,  Fang Fang

公开(公告)号：US09657712B2

公开(公告)日：2017-05-23

申请号：US13603446

申请日：2012-09-05

申请人： Zupeng Fang ,  Dan Fang ,  Fang Fang ,  Yafeng Zhao

发明人： Zupeng Fang ,  Dan Fang ,  Fang Fang ,  Yafeng Zhao

IPC分类号： F03D3/04 ,  F03D3/00 ,  F03D15/00

CPC分类号： F03D3/0463 ,  F03D3/005 ,  F03D3/0427 ,  F03D9/35 ,  F03D15/00 ,  F03D15/10 ,  F05B2240/13 ,  F05B2240/912 ,  Y02B10/30 ,  Y02E10/721 ,  Y02E10/728 ,  Y02E10/74

摘要： A wind power station with wind concentrating structure includes a wind concentrating structure, which includes a multiple of floors and a hollow cylindrical central tower (28) running through the multiple of floors; a concentrated drive shaft assembly (2) is provided at a center point O of the central tower (28) being coaxial with a ground central axis (1) and running through each floor of the central tower (28); a impeller (3) is installed on the concentrated drive shaft assembly (2) in each floor of the central tower, the impeller is a vertical axis impeller or a horizontal axis impeller; two or more sub-buildings are radially provided from a original point which is a center O of the central tower (28), outer walls of the sub-buildings are connected with a outer wall of the central tower (28) to form a speed-increasing type windage with the floor (29), a ceiling cover (13) and a ceiling cover supporting truss (14).

公开(公告)号：US20170020173A1

公开(公告)日：2017-01-26

申请号：US15204991

申请日：2016-07-07

申请人： Fang Fang ,  Jiran Zhang ,  Xifei Yang ,  Chuanwang Hu ,  Jian Chen ,  Guocheng Du

发明人： Fang Fang ,  Jiran Zhang ,  Xifei Yang ,  Chuanwang Hu ,  Jian Chen ,  Guocheng Du

IPC分类号： A23L5/20 ,  A23L27/50 ,  A23L23/00 ,  C12N1/20 ,  C12R1/07

CPC分类号： A23L5/28 ,  A23L27/50 ,  C12N1/20 ,  C12R1/07

摘要： The present invention provides a method for improving the quality of soy sauce using Bacillus amyloliquefaciens, which relates to the field of microbiology and food technology. The method comprises inoculating Bacillus amyloliquefaciens BBE JY06 during soy sauce fermentation. With Bacillus amyloliquefaciens addition during soy sauce fermentation, the aroma and tastes of soy sauce is improved and the ethyl carbamate content in soy sauce is decreased as well.

摘要翻译： 本发明提供了一种使用解淀粉芽孢杆菌（Bacillus amyloliquefaciens）提高酱油质量的方法，其涉及微生物学和食品技术领域。 该方法包括在酱油发酵过程中接种解淀粉芽孢杆菌BBE JY06。 在酱油发酵过程中加入解淀粉芽孢杆菌后，酱油的香气和口感得到改善，酱油中的氨基甲酸乙酯含量也降低。

公开(公告)号：US09309128B2

公开(公告)日：2016-04-12

申请号：US13264225

申请日：2010-04-14

申请人： John Vedamuthu Kennedy ,  Richard John Futter ,  Fang Fang ,  Andreas Markwitz

发明人： John Vedamuthu Kennedy ,  Richard John Futter ,  Fang Fang ,  Andreas Markwitz

IPC分类号： C01G9/03 ,  B82Y30/00 ,  C04B35/453 ,  C04B35/622 ,  C04B35/626 ,  G01N33/00

CPC分类号： C01G9/03 ,  B82Y30/00 ,  C01P2002/54 ,  C01P2002/72 ,  C01P2002/76 ,  C01P2004/03 ,  C01P2004/16 ,  C01P2004/54 ,  C01P2006/40 ,  C01P2006/60 ,  C04B35/453 ,  C04B35/62231 ,  C04B35/6268 ,  C04B2235/3279 ,  C04B2235/3284 ,  C04B2235/526 ,  C04B2235/5264 ,  G01N33/0027

摘要： A method for preparing zinc oxide nanostructures using arc discharge is disclosed. The method comprises the provision of an anode and a cathode in an arc discharge chamber. Current is supplied to the anode and the cathode to establish an arc discharge between the cathode and the anode to vaporize the anode and produce zinc oxide nanostructures. Contemplated is the use of the zinc oxide nanostructures to produce components that have applications in, for example, optoelectronics, energy storage devices, field emission devices, and sensors such as UV photosensors, gas sensors and humidity sensors. Disclosed is a gas sensor and method for its production, where said method comprises the provision of a sensor substrate comprising a conducting thin film at least partially covering at least two regions on at least one surface of a sensor substrate material to define a gap in the conducting thin film, the application of a mixture of zinc oxide nanostructures and a non-ionic polymer to at least a portion of the gap in the conducting thin film to thereby bridge the gap. Optionally contemplated is a step of annealing the mixture of zinc oxide nanostructures and non-ionic polymer applied to said sensor substrate to produce the sensor component.

摘要翻译： 公开了一种使用电弧放电制备氧化锌纳米结构的方法。 该方法包括在电弧放电室中提供阳极和阴极。 电流被提供给阳极和阴极，以在阴极和阳极之间建立电弧放电，以蒸发阳极并产生氧化锌纳米结构。 考虑使用氧化锌纳米结构来生产在例如光电子学，能量存储器件，场致发射器件以及诸如UV光电传感器，气体传感器和湿度传感器的传感器中应用的部件。 公开了一种用于其生产的气体传感器和方法，其中所述方法包括提供传感器基底，其包括导电薄膜，至少部分地覆盖传感器基底材料的至少一个表面上的至少两个区域，以在 导电薄膜，将氧化锌纳米结构和非离子聚合物的混合物施加到导电薄膜中的间隙的至少一部分，从而桥接间隙。 可以预期的是退火施加到所述传感器基底上的氧化锌纳米结构和非离子聚合物的混合物以产生传感器部件的步骤。