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公开(公告)号:US20050064543A1
公开(公告)日:2005-03-24
申请号:US10487078
申请日:2002-08-15
申请人: Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
发明人: Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
IPC分类号: G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07K1/22 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/11 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/00
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00 , C07K14/705 , C12N9/1205 , C12N9/16 , C12N9/6421
摘要: Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其它实施方案提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US20050176944A1
公开(公告)日:2005-08-11
申请号:US10487092
申请日:2002-08-16
申请人: Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人: Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号: G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号: C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要: Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译: 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子(INTSIG)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号:US20070092885A1
公开(公告)日:2007-04-26
申请号:US11378616
申请日:2006-03-20
申请人: Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
发明人: Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号:US20050019763A1
公开(公告)日:2005-01-27
申请号:US10473451
申请日:2002-04-05
申请人: Ameena Gandhi , Angelo Delegeane , Anita Swarnakar , April Hafalia , Brendan Duggan , Bridget Warren , Brooke Emerling , Chandra Arvizu , Cynthia Honchell , Deborah Kallick , Dyung Lu , Ernestine Lee , Henry Yue , Ian Forsythe , Jayalaxmi Ramkumar , Jennifer Griffin , Joana Li , Kavitha Thangavelu , Mariah Baughn , Monique Yao , Madhusudan Sanjanwala , Narinder Chawla , Neil Burford , Preeti Lal , Shanya Becha , Soo Lee , Vicki Elliott , Wen Luo , Yan Lu , Yu-mei Wang
发明人: Ameena Gandhi , Angelo Delegeane , Anita Swarnakar , April Hafalia , Brendan Duggan , Bridget Warren , Brooke Emerling , Chandra Arvizu , Cynthia Honchell , Deborah Kallick , Dyung Lu , Ernestine Lee , Henry Yue , Ian Forsythe , Jayalaxmi Ramkumar , Jennifer Griffin , Joana Li , Kavitha Thangavelu , Mariah Baughn , Monique Yao , Madhusudan Sanjanwala , Narinder Chawla , Neil Burford , Preeti Lal , Shanya Becha , Soo Lee , Vicki Elliott , Wen Luo , Yan Lu , Yu-mei Wang
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P9/00 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , A01K67/00 , C07H21/04
CPC分类号: C12N9/6421 , A01K2217/05 , A61K38/00
摘要: The invention provides human protein modification and maintenance molecules (PMOD) and polynucleotides which identify and encode PMOD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMOD.
摘要翻译: 本发明提供了鉴定和编码PMOD的人蛋白质修饰和维持分子(PMOD)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与PMOD异常表达相关的紊乱的方法。
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公开(公告)号:US20060068481A1
公开(公告)日:2006-03-30
申请号:US10979095
申请日:2004-11-02
申请人: Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Henry Yue , Monique Yao , Preeti Lal , Farrah Khan
发明人: Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Henry Yue , Monique Yao , Preeti Lal , Farrah Khan
CPC分类号: C12N9/1205 , A61K38/00 , C07H21/04
摘要: The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
摘要翻译: 本发明提供鉴定和编码PKIN的人类激酶(PKIN)和多核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与PKIN的异常表达相关的障碍的方法。
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公开(公告)号:US20050164275A1
公开(公告)日:2005-07-28
申请号:US11048744
申请日:2005-02-03
申请人: Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人: Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
CPC分类号: C12N9/16 , A01K2217/05
摘要: The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
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公开(公告)号:US20050202478A1
公开(公告)日:2005-09-15
申请号:US11048068
申请日:2005-02-02
申请人: Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人: Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
摘要: The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
摘要翻译: 本发明提供了人类磷酸二酯酶(HPDE)和识别和编码HPDE的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HPDE异常表达相关的疾病的方法。
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公开(公告)号:US20050048623A1
公开(公告)日:2005-03-03
申请号:US10959539
申请日:2004-10-06
申请人: Jennifer Hillman , Preeti Lal , Y. Tang , Henry Yue , Janice Au-Young , Olga Bandman , Yalda Azimzai , Junming Yang , Dyung Lu , Mariah Baughn , Chandra Arvizu , Purvi Shah
发明人: Jennifer Hillman , Preeti Lal , Y. Tang , Henry Yue , Janice Au-Young , Olga Bandman , Yalda Azimzai , Junming Yang , Dyung Lu , Mariah Baughn , Chandra Arvizu , Purvi Shah
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00
摘要: The invention provides human cell cycle and proliferation proteins (CCYPR) and polynucleotides which identify and encode CCYPR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CCYPR.
摘要翻译: 本发明提供鉴定和编码CCYPR的人类细胞周期和增殖蛋白(CCYPR)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与CCYPR表达相关的疾病的方法。
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公开(公告)号:US20050048610A1
公开(公告)日:2005-03-03
申请号:US10874706
申请日:2004-06-24
申请人: Preeti Lal , Junming Yang , Henry Yue , Jennifer Jackson , Y. Tang , Olga Bandman , Neil Burford , Mariah Baughn , Yalda Azimzai , Dyung Lu , Janice Au-Young , Chandra Arvizu
发明人: Preeti Lal , Junming Yang , Henry Yue , Jennifer Jackson , Y. Tang , Olga Bandman , Neil Burford , Mariah Baughn , Yalda Azimzai , Dyung Lu , Janice Au-Young , Chandra Arvizu
IPC分类号: A61K38/00 , C07K14/47 , C07K14/705 , C07H21/04
CPC分类号: C07K14/705 , A01K2217/05 , A61K38/00 , C07K14/47
摘要: This invention relates to nucleic acid and amino acid sequences of human transport proteins and to the use of these sequences in the diagnosis, treatment, and prevention of transport, metabolic, neurological, cardiovascular, reproductive, and immune disorders, and cell proliferative disorders including cancer.
摘要翻译: 本发明涉及人类运输蛋白的核酸和氨基酸序列,以及这些序列用于诊断,治疗和预防运输,代谢,神经,心血管,生殖和免疫疾病以及包括癌症的细胞增殖性疾病 。
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公开(公告)号:US20050037466A1
公开(公告)日:2005-02-17
申请号:US10935190
申请日:2004-09-08
申请人: Janice Au-Young , Olga Bandman , Y. Tang , Henry Yue , Yalda Azimzai , Neil Burford , Mariah Baughn , Dyung Lu , Jennifer Hillman , Chandra Arvizu , Preeti Lal
发明人: Janice Au-Young , Olga Bandman , Y. Tang , Henry Yue , Yalda Azimzai , Neil Burford , Mariah Baughn , Dyung Lu , Jennifer Hillman , Chandra Arvizu , Preeti Lal
IPC分类号: A61K38/00 , C07K14/705 , C07K14/72 , C07H21/04
CPC分类号: C07K14/723 , A61K38/00 , C07K14/705
摘要: The invention provides human receptors and associated proteins (RECAP) and polynucleotides which identify and encode RECAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of RECAP.
摘要翻译: 本发明提供识别和编码RECAP的人受体和相关蛋白(RECAP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与RECAP表达相关的疾病的方法。
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