Abstract:
[wherein m and n may be the same or different and each represents an integer of 1 to 3 wherein m+n is 4 or less; R1 represents —NR4R5 (wherein R4 and R5 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or the like); R2 represents the above Formula (II), Formula (IV) or the like; A represents a single bond, —C(═O)—, —SO2—, —OC(═O)— or the like; and R3 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl or the like]Bicyclic pyrimidine derivatives represented by the above Formula (I), or quaternary ammonium salts thereof, or pharmaceutically acceptable salts thereof, or the like, are provided. These have anti-inflammatory activities or modulation activities on the functions of TARC and/or MDC and are useful for treating and/or preventing a disease which is related to T cells, such as an allergic disease, an autoimmune disease or transplant rejection.
Abstract translation:[其中m和n可以相同或不同,并且各自表示1〜3的整数,其中m + n为4以下; R 1表示-NR 4 R 5(其中R 4,R 5和R 5) 可以相同或不同,各自表示氢原子,取代或未取代的低级烷基,取代或未取代的芳烷基等); R 2表示上述式(II),式(IV)等; A表示单键,-C(-O) - , - SO 2 - , - OC(-O) - 等; 和R 3表示取代或未取代的低级烷基,取代或未取代的环烷基,取代或未取代的芳烷基等〕由上式(I)表示的双环嘧啶衍生物或其季铵盐或药学上可接受的盐 可接受的盐等。 它们具有对TARC和/或MDC的功能的抗炎活性或调节活性,并且可用于治疗和/或预防与T细胞相关的疾病,例如过敏性疾病,自身免疫疾病或移植排斥反应。
Abstract:
A static electricity eliminating apparatus comprising; (A) a first electrically conductive piece and a second electrically conductive piece which are disposed so as to face each other through an insulating layer, and (B) a discharge means having one end electrically connected to the first electrically conductive piece and other end electrically connected to the second electrically conductive piece, wherein a charge electrostatically induced in the first electrically conductive piece and the second electrically conductive piece due to a contact of a static-electricity-charged object with the first electrically conductive piece is accumulated between the first electrically conductive piece and the second electrically conductive piece by dielectric polarization, and then, the charge is discharged with the discharge means in a state where the first electrically conductive piece and the second electrically conductive piece are not grounded.
Abstract:
Provided is a flame retardant adhesive composition including (A) a halogen-free epoxy resin, (B) a thermoplastic resin and/or a synthetic rubber, (C) a curing agent, (D) a curing accelerator, and (E) a phosphorus-containing filler. Also provided are an adhesive sheet, a coverlay film, and a flexible copper-clad laminate prepared using such a composition. A cured product yielded by curing the composition, as well as the adhesive sheet, the coverlay film, and the flexible copper-clad laminate display excellent flame retardancy and electrical characteristics (anti-migration properties).
Abstract:
An optical recording medium includes a substrate, a light transmission layer and a recording layer formed between the substrate and the light transmission layer, the recording layer containing at least one simple substance of a metal element M selected from a group consisting of Zn and La and an element X selected from a group consisting of S and O which can combine with the metal element M to form a compound of the element X with the metal element M and the optical recording medium being constituted so that upon being irradiated with a laser beam for recording data, a crystal of the compound of the element X with the metal element M is formed and grows to form a crystal region thereof. According to the thus constituted optical recording medium, a reproduced signal having a good C/N ratio can be obtained when data recorded in the recording layer are reproduced.
Abstract:
DC107 derivatives represented by formula (I) or pharmaceutically acceptable salts thereof which have antimicrobial activity and antitumor activity are provided: ##STR1## wherein R.sup.1 represents CO(CR.sup.4A R.sup.4B).sub.n1 (O(CH.sub.2).sub.p1).sub.n2 OR.sup.5 {wherein n1 represents an integer of 1 or 2; R.sup.4A and R.sup.4B are the same or different, and each represents hydrogen or lower alkyl; p1 and n2 each represents an integer of 1 to 10; and R.sup.5 represents hydrogen, lower alkyl, or the like), or ##STR2##
Abstract:
Described is an adhesive containing a polycarbodiimide resin having repeating units represented by the following formula:.paren open-st.R--N.dbd.C.dbd.N.paren close-st..sub.nwherein R is a divalent hydrocarbon group and n is an integer of 5 to 250, and also described is a flexible printed circuit board and a coverlay film fabricated using the above-described polycarbodiimide resin-containing adhesive.
Abstract translation:描述了含有具有由下式表示的重复单元的聚碳化二亚胺树脂的粘合剂:+545RN = C = N + 546 n其中R是二价烃基,n是5至250的整数,并且还描述了柔性印刷 电路板和使用上述含聚碳酰亚胺树脂的粘合剂制成的覆盖膜。
Abstract:
Mitomycin derivatives having the formula ##STR1## wherein X is acyl, lower alkyl, alkoxycarbonyl aryloxycarbonyl or aralkoxycarbonyl;Y is hydrogen or methyl;Z is hydrogen, methyl, acyl or allyloxycarbonyl;one of R.sub.1 and R.sub.2 represents carbamoyloxymethyl and the other represents hydrogen, or R.sub.1 and R.sub.2 together represent methylene, show antibacterial and antitumor activities.
Abstract:
An image processing apparatus in which a digital image signal is produced and characteristics thereof are converted, e.g., gradation-processed. The result of this processing is used to produce a pulse-width-modulated signal, which is used for image formation. Image forming conditions are detected and the processing is controlled in accordance with the result of such detection.
Abstract:
Proposed are a management apparatus and a management method capable of facilitating resource management With the provided management apparatus and management method for managing a resource allocated to a virtual node that provides a file sharing service to a client in units of a resource management group configured from a plurality of mutually associated resources, an association between the resources is extracted based on history information of access from the client, and the associated resource management groups are integrated based on the extracted association between the resources. Thus, it is possible to reduce the number of resource management groups to be managed, and resource management is thereby facilitated.