公开(公告)号：US10678187B2

公开(公告)日：2020-06-09

申请号：US15545611

申请日：2016-02-04

Applicant: IMEC VZW

Inventor： Richard Stahl ,  Tom Claes ,  Xavier Rottenberg ,  Geert Vanmeerbeeck ,  Andy Lambrechts

IPC: H04N5/89 ,  H04N9/47 ,  A62B1/04 ,  G03H1/04 ,  G02B27/00 ,  G02B21/00 ,  G01N15/14 ,  G02B6/122 ,  H04N5/225 ,  H04N13/00 ,  G02B6/12 ,  H04N5/374

Abstract: Embodiments described herein relate to a large area lens-free imaging device. One example is a lens-free device for imaging one or more objects. The lens-free device includes a light source positioned for illuminating at least one object. The lens-free device also includes a detector positioned for recording interference patterns of the illuminated at least one object. The light source includes a plurality of light emitters that are positioned and configured to create a controlled light wavefront for performing lens-free imaging.

公开(公告)号：US20190310584A1

公开(公告)日：2019-10-10

申请号：US16467612

申请日：2017-12-08

Applicant: IMEC VZW

Inventor： Ziduo Lin ,  Abdulkadir Yurt ,  Richard Stahl ,  Geert Vanmeerbeeck

IPC: G03H1/04 ,  G03H1/00

Abstract: Example embodiments relate to methods and imaging systems for holographic imaging. One embodiment includes a method for holographic imaging of an object. The method includes driving a laser using a current which is below a threshold current of the laser. The method also includes illuminating the object using illumination light output by the laser. Further, the method includes detecting an interference pattern formed by object light, having interacted with the object, and reference light of the illumination light.

公开(公告)号：US20180181062A1

公开(公告)日：2018-06-28

申请号：US15847521

申请日：2017-12-19

Applicant: IMEC vzw

Inventor： Abdulkadir Yurt ,  Geert Vanmeerbeeck ,  Richard Stahl ,  Ziduo Lin

IPC: G03H1/02 ,  G03H1/12

Abstract: An apparatus for in-line holographic imaging is disclosed. In one aspect, the apparatus includes at least a first light source and a second light source arranged for illuminating an object arranged in the apparatus with a light beam. The apparatus also includes an image sensor arranged to detect at least a first and a second interference pattern, wherein the first interference pattern is formed when the object is illuminated by the first light source and the second interference pattern is formed when the object is illuminated by the second light source. The first and second interference patterns are formed by diffracted light, being scattered by the object, and undiffracted light of the light beam. The at least first and second light sources are arranged at different angles in relation to the object, and possibly illuminate the object using different wavelengths.

公开(公告)号：US20180143079A1

公开(公告)日：2018-05-24

申请号：US15821918

申请日：2017-11-24

Applicant: IMEC VZW

Inventor： Abdulkadir YURT ,  Ziduo Lin ,  Richard Stahl ,  Geert Vanmeerbeeck

IPC: G01J9/02

CPC classification number: G01J9/02 ,  G01J9/0215 ,  G01J2009/0223 ,  G03H1/0443 ,  G03H1/0465 ,  G03H2001/0447 ,  G03H2223/12 ,  G03H2223/19

Abstract: According to a first aspect, there is provided a method of holographic wavefront sensing, the method including: receiving a light beam, which has a wavefront to be analyzed, on a transparent, flat substrate, which is provided with a lattice of opaque dots, wherein the substrate is arranged above an image sensor; detecting by the image sensor an interference pattern formed by diffracted light, being scattered by the opaque dots, and undiffracted light of the light beam received by the image sensor; processing the detected interference pattern to digitally reconstruct a representation of a displaced lattice of opaque dots, which would form the interference pattern on the image sensor upon receiving the light with a known wavefront; and comparing the representation of the displaced lattice to a known representation of the lattice of opaque dots on the substrate to determine a representation of the wavefront form of the received light beam.

公开(公告)号：US20170115201A1

公开(公告)日：2017-04-27

申请号：US15129267

申请日：2015-04-03

Applicant: IMEC VZW

Inventor： Veerle Reumers ,  Dries Braeken ,  Geert Vanmeerbeeck ,  Richard Stahl ,  Andy Lambrechts

IPC: G01N15/10 ,  G01N15/14 ,  G03H1/04 ,  G01N33/50 ,  G03H1/00 ,  G01N21/47 ,  G01N21/17

Abstract: The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells.