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    Modular impeller
    22.
    外观设计
    Modular impeller 有权

    公开(公告)号：USD1016098S1

    公开(公告)日：2024-02-27

    申请号：US29773911

    申请日：2021-03-12

    Applicant: Life Technologies Corporation

    Designer： Nephi D. Jones ,  Jason D. Brown

    Abstract: FIG. 1 is a top perspective view of a modular impeller showing our new design;
    FIG. 2 is a bottom perspective view thereof;
    FIG. 3 is a right side elevational view thereof;
    FIG. 4 is a left side elevational view thereof;
    FIG. 5 is a front elevational view thereof;
    FIG. 6 is a rear elevational view thereof;
    FIG. 7 is a top plan view thereof; and,
    FIG. 8 is a bottom plan view thereof.

    Continuous Sample Purification Systems and Methods
    24.
    发明申请
    Continuous Sample Purification Systems and Methods 有权

    公开(公告)号：US20220339554A1

    公开(公告)日：2022-10-27

    申请号：US17861638

    申请日：2022-07-11

    Applicant: Life Technologies Corporation

    Inventor： Scott P. Collins ,  Federico Carlos Rodriguez Peralta ,  Nephi D. Jones ,  Christopher D. Brau

    IPC: B01D11/04 ,  B01D11/02 ,  B01D15/36 ,  B01D15/38

    Abstract: Sample purification systems include a particle extraction assembly having a mixing compartment and a settling compartment. A biological sample is mixed with two liquid phases formulated to effectuate transfer of a biological molecule into a first phase and particulate contaminants into a second phase. The first phase includes a solubilizing salt, the second phase includes an organic molecule, and the mixture can have little or no monoatomic salt or dextran. The molecule-containing first phase can be optionally concentrated without also concentrating the particulate contaminants and introduced into a multi-stage liquid-liquid extractor, by which the biological molecule or molecular contaminants are extracted from the first phase into a third phase, thereby purifying the molecule away from contaminants. The extracted sample can be further purified through a series of processing steps. The system can be run in continuously mode to maintain sterility of the sample.

    Continuous sample purification systems and methods
    25.
    发明授权
    Continuous sample purification systems and methods 有权

    公开(公告)号：US11426679B2

    公开(公告)日：2022-08-30

    申请号：US16067509

    申请日：2016-12-21

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Scott P. Collins ,  Federico Carlos Rodriguez Peralta ,  Nephi D. Jones ,  Christopher D. Brau

    IPC: B01D11/04 ,  B01D15/36 ,  B01D15/38 ,  B01D11/02

    Abstract: Sample purification systems include a particle extraction assembly having a mixing compartment and a settling compartment. A biological sample is mixed with two liquid phases formulated to effectuate transfer of a biological molecule into a first phase and particulate contaminants into a second phase. The first phase includes a solubilizing salt, the second phase includes an organic molecule, and the mixture can have little or no monoatomic salt or dextran. The molecule-containing first phase can be optionally concentrated without also concentrating the particulate contaminants and introduced into a multi-stage liquid-liquid extractor, by which the biological molecule or molecular contaminants are extracted from the first phase into a third phase, thereby purifying the molecule away from contaminants. The extracted sample can be further purified through a series of processing steps. The system can be run in continuously mode to maintain sterility of the sample.

    Flexible bioprocessing container with partial dividing partition
    26.
    发明授权
    Flexible bioprocessing container with partial dividing partition 有权

    公开(公告)号：US11268056B2

    公开(公告)日：2022-03-08

    申请号：US16067495

    申请日：2016-12-21

    Applicant: LIFE TECHNOLOGIES CORPORATION ,  LIFE TECHNOLOGICES AG

    Inventor： Lars Norderhaugh ,  Angel Varela-Rohena ,  Nephi D. Jones

    IPC: C12M1/26 ,  B03C1/30 ,  B03C1/01 ,  B03C1/28 ,  A61M1/36 ,  B01L3/00 ,  C12M3/00 ,  C12M1/00 ,  C12M1/12 ,  C07K16/28

    Abstract: Methods of separating magnetic particles from a fluid include introducing a fluid mixture that includes a liquid media, a biological component, and magnetic particles into an internal compartment of a container through an inlet, allowing at least a portion of the mixture to travel around a partition formed within the internal compartment and then exit the internal compartment through an outlet on the opposite side of the partition, and applying a magnetic field to the mixture in the internal compartment so that the magnetic particles are retained within the container or internal compartment thereof by the magnetic field. The partition is formed by permanently or reversibly securing upper and lower container walls together, such as by welding or pressing, between the inlet and the outlet such that the media and biological component must flow around the partition and through the magnetic field to exit the internal compartment through the outlet.

    FLUID MIXING SYSTEMS WITH ADJUSTABLE MIXING ELEMENT
    27.
    发明申请
    FLUID MIXING SYSTEMS WITH ADJUSTABLE MIXING ELEMENT 审中-公开

    公开(公告)号：US20190322971A1

    公开(公告)日：2019-10-24

    申请号：US16502245

    申请日：2019-07-03

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Michael E. Goodwin ,  Nephi D. Jones

    IPC: C12M1/00 ,  B01F15/00 ,  B01F7/00 ,  B01F7/02 ,  C12M1/06 ,  C12M3/00

    Abstract: A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.

    ACOUSTICALLY SETTLED LIQUID-LIQUID SAMPLE PURIFICATION SYSTEM
    30.
    发明申请
    ACOUSTICALLY SETTLED LIQUID-LIQUID SAMPLE PURIFICATION SYSTEM 审中-公开

    公开(公告)号：US20170354901A1

    公开(公告)日：2017-12-14

    申请号：US15521227

    申请日：2015-10-23

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Scott P. Collins ,  Christopher D Brau ,  Nephi D. Jones

    IPC: B01D11/04 ,  G01N1/34

    CPC classification number: B01D11/0423 ,  B01D11/043 ,  B01D11/0449 ,  B01D11/0457 ,  G01N1/34 ,  G01N2001/4061

    Abstract: A sample purification system includes a container assembly bounding a sample purification compartment and having an upper end and an opposing lower end, the sample purification compartment comprising mixing zones and settling zones. A plurality of shielding elements are positioned within the sample purification compartment so as to at least partially separate adjacent mixing zones and settling zones or separate adjacent mixing zones, the mixing zones being in fluid communication with the settling zones. A mixing element is disposed within each mixing zone. An acoustic wave settler is aligned with a portion of the container assembly, the acoustic wave settler being configured to emit an acoustic wave through the portion of the container assembly and a mixture disposed therein, the acoustic wave coalescing fluid phase droplets disposed in the mixture to increase the buoyancy or density of the fluid phase droplets.

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