COMPACT CIRCULAR SAW
    25.
    发明申请
    COMPACT CIRCULAR SAW 审中-公开
    紧凑圆锯

    公开(公告)号:US20110185581A1

    公开(公告)日:2011-08-04

    申请号:US12835393

    申请日:2010-07-13

    CPC classification number: B23D45/16 B25F5/02

    Abstract: A circular saw includes a housing, a motor having a rotating axis and a center of gravity on the rotating axis, a handle, a circular blade, a fixed guard, and a base plate having a width supporting the housing. The motor and the circular blade are parallel or coplanar with respect to each other and the circular saw does not extend beyond the width of the base plate in the width direction.

    Abstract translation: 圆锯包括壳体,具有旋转轴线的旋转轴线和重心在旋转轴上的电机,手柄,圆形刀片,固定护罩和具有支撑壳体的宽度的底板。 马达和圆形刀片相对于彼此平行或共面,并且圆锯不延伸超过基板在宽度方向上的宽度。

    Method for accurately estimating pKa of molecules using atom type definitions and partial least squares
    28.
    发明授权
    Method for accurately estimating pKa of molecules using atom type definitions and partial least squares 失效
    使用原子类型定义和偏最小二乘法准确估计分子的pKa的方法

    公开(公告)号:US07006921B1

    公开(公告)日:2006-02-28

    申请号:US09626099

    申请日:2000-07-26

    CPC classification number: G06F19/704

    Abstract: A computer implemented software method enables the prediction of the pKa of an arbitrary molecule based upon a knowledge of the molecular structure of that molecule and a statistical analysis of the molecular structures of a group of molecules (training set) for which the pKa is known. Hierarchical atom connectivity trees are constructed for the training set and the various atoms types identified in each molecule are associated in a bit string for that molecule and also associated with the experimentally determined pKa for that molecule. PLS analysis of the training set data yields coefficients associated with each atom type represented in the bit strings. A hierarchical atom connectivity tree may then be constructed for the molecule of interest. The predicted pKa is determined by multiplying the number of occurrences of each atom type in the molecule of interest by the PLS coefficient determined for that atom type and summing the resulting multiplications.

    Abstract translation: 基于对该分子的分子结构的了解和一组分子的分子结构的统计分析(训练集合),计算机实现的软件方法能够预测任意分子的pK a a ),已知pK 。 为训练集合构建分层原子连接性树,并且在每个分子中鉴定的各种原子类型与该分子的位串相关联,并且还与该分子的实验确定的pK 相关联。 训练集数据的PLS分析产生与位串中表示的每个原子类型相关联的系数。 然后可以为感兴趣的分子构建分层的原子连接性树。 通过将感兴趣分子中每个原子类型的出现次数乘以为该原子类型确定的PLS系数并将所得到的乘法相加来确定预测的pK

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