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21.发明授权Reagent preparing device, specimen processing system and reagent preparing method 有权试剂制备装置，试样处理系统和试剂制备方法公开(公告)号：US09164021B2
公开(公告)日：2015-10-20
申请号：US12711676
申请日：2010-02-24
CPC分类号： G01N15/14 , G01N1/38 , G01N35/1002 , G01N2035/00534
摘要： A reagent preparing device capable of supplying a mixed solution, including a first liquid and a second liquid, to a measurement section for measuring a specimen using the mixed solution as a reagent, the reagent preparing device comprising: a first mixed solution container for accommodating the mixed solution; a second mixed solution container for accommodating the mixed solution; and a controller for controlling supply of the first liquid and the second liquid to supply the first liquid and the second liquid to the first mixed solution container, and to supply the first liquid and the second liquid to the second mixed solution container, is disclosed. A specimen processing system, and a reagent preparing method are also disclosed.
摘要翻译： 一种能够将包含第一液体和第二液体的混合溶液供给到使用该混合溶液作为试剂测定试样的测定部的试剂调制装置，所述试剂调制装置包括：第一混合溶液容器， 混合溶液; 用于容纳混合溶液的第二混合溶液容器; 以及控制器，用于控制第一液体和第二液体的供应，以将第一液体和第二液体供应到第一混合溶液容器，并将第一液体和第二液体供应到第二混合溶液容器。 还公开了样品处理系统和试剂制备方法。
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公开(公告)号：US08894932B2
公开(公告)日：2014-11-25
申请号：US12732964
申请日：2010-03-26
CPC分类号： G01N27/06 , G01N35/00594 , G01N35/00693 , G01N2035/00673 , Y10T436/25625
摘要： A reagent preparing device capable of supplying a predetermined reagent, which includes a first liquid and a second liquid different from the first liquid, to a measurement section for measuring a specimen using the reagent, comprising: a reagent preparing section for preparing the predetermined reagent; a characteristic measurement device for measuring characteristic of the reagent prepared by the reagent preparing section; and a controller configured for performing operations comprising, controlling the supply of reagent prepared by the reagent preparing section to the measurement section according to the measurement result by the characteristic measurement device, and calibrating the characteristic measurement device based on a known characteristic value of a standard liquid having the known characteristic value and a measurement result obtained by measuring the characteristic of the standard liquid by the characteristic measurement device, is disclosed. A specimen processing system is also disclosed.
摘要翻译： 一种试剂调制装置，其能够将包含第一液体和与第一液体不同的第二液体的规定试剂供给到使用试剂测定试样的测定部，其特征在于，包括：准备所述试剂的试剂调制部; 用于测量由所述试剂调制部制备的试剂的特性的特征测量装置; 以及控制器，其被配置为执行以下操作，所述控制器包括：根据所述特性测量装置的测量结果，控制向所述测量部分供应由所述试剂调制部件准备的试剂，并且基于标准的已知特征值校准所述特性测量装置 公开了具有已知特征值的液体和通过特征测量装置测量标准液体的特性而获得的测量结果。 还公开了一种样品处理系统。
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公开(公告)号：US20110184570A1
公开(公告)日：2011-07-28
申请号：US13013390
申请日：2011-01-25
申请人： Noriyuki Nakanishi , Yutaka Ikeda
发明人： Noriyuki Nakanishi , Yutaka Ikeda
IPC分类号： G05D7/06
CPC分类号： G01N35/00663 , G01N1/38 , G01N35/1002 , G01N2035/00534 , G01N2035/00673
摘要： A reagent preparing apparatus for preparing reagent by mixing a concentrated reagent and a diluting liquid and supplying the prepared reagent to a clinical sample measurement apparatus which measures a clinical sample using the supplied reagent, the reagent preparing apparatus comprising: a chamber for mixing the concentrated reagent and the diluting liquid; a liquid quality measurement part for measuring a quality of the diluting liquid; and a controller for controlling a flow of the diluting liquid based on the quality of the diluting liquid measured by the liquid quality measurement part is disclosed.
摘要翻译： 一种试剂调制装置，用于通过混合浓缩试剂和稀释液制备试剂，并将制备的试剂供应到使用所提供的试剂测量临床样品的临床样品测量装置，所述试剂制备装置包括：用于混合浓缩试剂 和稀释液; 用于测量稀释液质量的液体质量测量部件; 公开了一种用于基于由液体质量测量部件测量的稀释液质量来控制稀释液体流动的控制器。
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24.发明申请REAGENT PREPARING DEVICE, SPECIMEN MEASURING DEVICE AND REAGENT PREPARING METHOD 有权试剂制备装置，样本测量装置和试剂制备方法公开(公告)号：US20100216223A1
公开(公告)日：2010-08-26
申请号：US12711640
申请日：2010-02-24
CPC分类号： G01N35/00663 , G01N15/14 , G01N35/1002 , G01N2035/00544 , G01N2035/00673 , Y10T436/10 , Y10T436/25625
摘要： A reagent preparing device for preparing a reagent to be supplied to a measurement device for measuring a specimen, comprising: a first liquid storage unit for storing a first liquid; a reagent storage unit for storing a prepared reagent, including the first liquid and a second liquid different from the first liquid; a first liquid discarding unit for discarding the first liquid stored in the first liquid storage unit; and a controller configured for measuring an accumulated time of the first liquid in the first liquid storage unit; and controlling the first liquid discarding unit to discard the first liquid stored in the first liquid storage unit when the accumulated time reaches a predetermined time is disclosed. A specimen measuring device and a reagent preparing method are also disclosed.
摘要翻译： 一种试剂调制装置，用于制备供给到用于测量试样的测量装置的试剂，包括：第一液体存储单元，用于储存第一液体; 用于存储包含第一液体和不同于第一液体的第二液体的准备试剂的试剂储存单元; 第一液体丢弃单元，用于丢弃存储在第一液体存储单元中的第一液体; 以及控制器，被配置为测量第一液体存储单元中的第一液体的累积时间; 并且当累积时间达到预定时间时，控制第一液体丢弃单元丢弃存储在第一液体存储单元中的第一液体。 还公开了一种样品测量装置和试剂制备方法。
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公开(公告)号：US5589502A
公开(公告)日：1996-12-31
申请号：US558772
申请日：1995-11-15
IPC分类号： C07D263/04 , C07D263/06 , C07D305/14 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , A61K31/335
CPC分类号： C07D263/04 , C07D263/06 , C07D305/14 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12
摘要： A compound represented by the formula [I]: ##STR1## wherein R.sup.3 represents a lower alkanoyl group; R.sup.4 represents a substituted or unsubstituted benzoyl group; ring A represents a substituted or unsubstituted cyclopropane ring; X represents a single bond or a group represented by --O--, --S-- or --NH--; R represents a substituted or unsubstituted lower alkyl group (wherein said lower alkyl group may have a cycloalkyl moiety), a substituted or unsubstituted aryl group or a substituted or unsubstituted aromatic heterocyclic group; E represents hydrogen atom or a group represented by --CO(CH.sub.2).sub.n ZY; Y represents a residue obtained from an amino acid or a dipeptide by removing hydroxyl group in one carboxyl group therefrom (wherein amino group existing in said residue may be protected, and carboxyl group existing in said residue may be esterified or amidated); Z represents a group represented by the formula of --O-- or --NH--; and n represents 1, 2, 3, 4, 5 or 6, or a pharmaceutically acceptable salt thereof. Said compounds have excellent antitumor activity so that they are useful in the prophylaxis or treatment of a wide range of tumors such as breast cancer, ovary cancer, lung cancer, malignant melanoma and the like.
摘要翻译： 由式[I]表示的化合物：其中R 3表示低级烷酰基; R4表示取代或未取代的苯甲酰基; 环A表示取代或未取代的环丙烷环; X表示单键或由-O - ， - S-或-NH-表示的基团; R表示取代或未取代的低级烷基（其中所述低级烷基可以具有环烷基部分），取代或未取代的芳基或取代或未取代的芳族杂环基; E表示氢原子或由-CO（CH 2）n ZY表示的基团; Y表示通过从其中除去一个羧基中的羟基从氨基酸或二肽获得的残基（其中存在于所述残基中的氨基可被保护，并且所述残基中存在的羧基可被酯化或酰胺化）; Z表示由式-O-或-NH-表示的基团; 和n表示1,2,3,4,5或6或其药学上可接受的盐。 所述化合物具有优异的抗肿瘤活性，因此它们可用于预防或治疗广泛范围的肿瘤如乳腺癌，卵巢癌，肺癌，恶性黑素瘤等。
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公开(公告)号：US09482682B2
公开(公告)日：2016-11-01
申请号：US13417886
申请日：2012-03-12
申请人： Yutaka Ikeda , Noriyuki Nakanishi
发明人： Yutaka Ikeda , Noriyuki Nakanishi
CPC分类号： G01N35/00663 , G01N35/00613 , G01N35/00712 , G01N2035/00673 , Y10T436/12 , Y10T436/25
摘要： The present invention is a reagent preparation apparatus, comprising: a reagent preparation unit configured to prepare a reagent for processing a sample; a measuring unit configured to measure a property of the reagent prepared by the reagent preparation unit; a waste section configured to discard the prepared reagent when a measurement result by the measuring unit does not meet a predetermined condition; and a controller configured to control a reagent preparation operation of the reagent preparation unit, wherein the controller controls the reagent preparation unit to stop the reagent preparation operation when a number of times of discarding a reagent has reached a predetermined plurality of times.
摘要翻译： 本发明是一种试剂调制装置，其特征在于，包括：试剂调制单元，其被配置为制备用于处理样品的试剂; 测量单元，被配置为测量由所述试剂调制单元制备的试剂的性质; 当所述测量单元的测量结果不满足预定条件时，废弃部分被配置为丢弃所述准备的试剂; 以及控制器，其被配置为控制所述试剂调制单元的试剂调制操作，其中，所述控制器控制所述试剂调制单元停止试剂准备操作，所述试剂停留次数达到预定次数。
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27.发明授权Reagent preparing device, specimen measuring device and reagent preparing method 有权试剂制备装置，试样测定装置及试剂制备方法公开(公告)号：US08906302B2
公开(公告)日：2014-12-09
申请号：US12711640
申请日：2010-02-24
CPC分类号： G01N35/00663 , G01N15/14 , G01N35/1002 , G01N2035/00544 , G01N2035/00673 , Y10T436/10 , Y10T436/25625
摘要： A reagent preparing device for preparing a reagent to be supplied to a measurement device for measuring a specimen, comprising: a first liquid storage unit for storing a first liquid; a reagent storage unit for storing a prepared reagent, including the first liquid and a second liquid different from the first liquid; a first liquid discarding unit for discarding the first liquid stored in the first liquid storage unit; and a controller configured for measuring an accumulated time of the first liquid in the first liquid storage unit; and controlling the first liquid discarding unit to discard the first liquid stored in the first liquid storage unit when the accumulated time reaches a predetermined time is disclosed. A specimen measuring device and a reagent preparing method are also disclosed.
摘要翻译： 一种试剂调制装置，用于制备供给到用于测量试样的测量装置的试剂，包括：第一液体存储单元，用于储存第一液体; 用于存储包含第一液体和不同于第一液体的第二液体的准备试剂的试剂储存单元; 第一液体丢弃单元，用于丢弃存储在第一液体存储单元中的第一液体; 以及控制器，被配置为测量第一液体存储单元中的第一液体的累积时间; 并且当累积时间达到预定时间时，控制第一液体丢弃单元丢弃存储在第一液体存储单元中的第一液体。 还公开了一种样品测量装置和试剂制备方法。
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28.发明申请REAGENT PREPARING DEVICE, REAGENT PREPARING METHOD AND SPECIMEN PROCESSING SYSTEM 有权试剂制备装置，试剂制备方法和样品处理系统公开(公告)号：US20100248289A1
公开(公告)日：2010-09-30
申请号：US12730557
申请日：2010-03-24
IPC分类号： G01N33/49
CPC分类号： G01N35/00663 , G01N2035/00673
摘要： A reagent preparing device for preparing a reagent to be supplied to a measurement section for measuring a specimen; the reagent preparing device comprising: a reagent preparing section for preparing a reagent including a first liquid and a second liquid, different from the first liquid; a reagent storage container, connected to the measurement section, for storing the reagent prepared by the reagent preparing section; and a controller configured for determining whether or not the reagent stored in the reagent storage container is suppliable to the measurement section based on reagent expiration date information related to an expiration date of the reagent stored in the reagent storage container, is disclosed. A reagent preparing method and a specimen processing system are also disclosed.
摘要翻译： 一种试剂调制装置，用于制备供给到用于测量试样的测量部分的试剂; 所述试剂调制装置包括：试剂调制部，其用于制备不同于所述第一液体的第一液体和第二液体的试剂; 试剂储存容器，连接到测量部分，用于储存由试剂制备部分制备的试剂; 以及控制器，其被配置为基于与存储在试剂储存容器中的试剂的有效期相关的试剂有效期限信息来确定存储在试剂储存容器中的试剂是否可供给测量部。 还公开了一种试剂制备方法和试样处理系统。
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公开(公告)号：US20100247383A1
公开(公告)日：2010-09-30
申请号：US12732964
申请日：2010-03-26
IPC分类号： G01N27/417
CPC分类号： G01N27/06 , G01N35/00594 , G01N35/00693 , G01N2035/00673 , Y10T436/25625
摘要： A reagent preparing device capable of supplying a predetermined reagent, which includes a first liquid and a second liquid different from the first liquid, to a measurement section for measuring a specimen using the reagent, comprising: a reagent preparing section for preparing the predetermined reagent; a characteristic measurement device for measuring characteristic of the reagent prepared by the reagent preparing section; and a controller configured for performing operations comprising, controlling the supply of reagent prepared by the reagent preparing section to the measurement section according to the measurement result by the characteristic measurement device, and calibrating the characteristic measurement device based on a known characteristic value of a standard liquid having the known characteristic value and a measurement result obtained by measuring the characteristic of the standard liquid by the characteristic measurement device, is disclosed. A specimen processing system is also disclosed.
摘要翻译： 一种试剂调制装置，其能够将包含第一液体和与第一液体不同的第二液体的规定试剂供给到使用试剂测定试样的测定部，其特征在于，包括：准备所述试剂的试剂调制部; 用于测量由所述试剂调制部制备的试剂的特性的特征测量装置; 以及控制器，其被配置为执行以下操作，所述控制器包括：根据所述特性测量装置的测量结果，控制向所述测量部分供应由所述试剂调制部件准备的试剂，并且基于标准的已知特征值校准所述特性测量装置 公开了具有已知特征值的液体和通过特征测量装置测量标准液体的特性而获得的测量结果。 还公开了一种样品处理系统。
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30.发明申请REAGENT PREPARING DEVICE, SPECIMEN PROCESSING SYSTEM AND REAGENT PREPARING METHOD 有权试剂制备装置，样品加工系统和试剂制备方法公开(公告)号：US20100216224A1
公开(公告)日：2010-08-26
申请号：US12711676
申请日：2010-02-24
IPC分类号： C12M1/36
CPC分类号： G01N15/14 , G01N1/38 , G01N35/1002 , G01N2035/00534
摘要： A reagent preparing device capable of supplying a mixed solution, including a first liquid and a second liquid, to a measurement section for measuring a specimen using the mixed solution as a reagent, the reagent preparing device comprising: a first mixed solution container for accommodating the mixed solution; a second mixed solution container for accommodating the mixed solution; and a controller for controlling supply of the first liquid and the second liquid to supply the first liquid and the second liquid to the first mixed solution container, and to supply the first liquid and the second liquid to the second mixed solution container, is disclosed. A specimen processing system, and a reagent preparing method are also disclosed.
摘要翻译： 一种能够将包含第一液体和第二液体的混合溶液供给到使用该混合溶液作为试剂测定试样的测定部的试剂调制装置，所述试剂调制装置包括：第一混合溶液容器， 混合溶液; 用于容纳混合溶液的第二混合溶液容器; 以及控制器，用于控制第一液体和第二液体的供应，以将第一液体和第二液体供应到第一混合溶液容器，并将第一液体和第二液体供应到第二混合溶液容器。 还公开了样品处理系统和试剂制备方法。
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