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    STIMULATION INDUCED NEURAL RESPONSE FOR DETECTION OF LEAD MOVEMENT
    25.
    发明申请
    STIMULATION INDUCED NEURAL RESPONSE FOR DETECTION OF LEAD MOVEMENT 有权

    公开(公告)号：US20220032059A1

    公开(公告)日：2022-02-03

    申请号：US16945639

    申请日：2020-07-31

    Applicant: Medtronic, Inc.

    Inventor： Rene A. Molina ,  Scott R. Stanslaski ,  Jadin C. Jackson ,  Christopher L. Pulliam ,  Eric J. Panken ,  Michelle A. Case ,  Abbey Beuning Holt Becker

    IPC: A61N1/36 ,  A61N1/375

    Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

    ADAPTIVE DEEP BRAIN STIMULATION USING HOMEOSTATIC WINDOW
    27.
    发明申请
    ADAPTIVE DEEP BRAIN STIMULATION USING HOMEOSTATIC WINDOW 有权

    公开(公告)号：US20210093851A1

    公开(公告)日：2021-04-01

    申请号：US17107257

    申请日：2020-11-30

    Applicant: Medtronic, Inc.

    Inventor： Scott R. Stanslaski ,  Thomas Adamski ,  Duane L. Bourget ,  Timothy J. Denison ,  Benjamin P. Isaacson ,  Eric J. Panken ,  Jeffrey Herron

    IPC: A61N1/05 ,  A61N1/36 ,  A61B5/00 ,  A61B5/04 ,  A61N1/372

    Abstract: Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.

    NEURAL OSCILLATORY SIGNAL SOURCE LOCATION DETECTION
    28.
    发明申请
    NEURAL OSCILLATORY SIGNAL SOURCE LOCATION DETECTION 审中-公开

    公开(公告)号：US20200338351A1

    公开(公告)日：2020-10-29

    申请号：US16395308

    申请日：2019-04-26

    Applicant: Medtronic, Inc.

    Inventor： Eric J. Panken ,  Christopher L. Pulliam ,  Jadin C. Jackson ,  Yizi Xiao

    IPC: A61N1/36 ,  G01B7/00 ,  A61B5/00 ,  A61N1/372 ,  A61N1/05

    Abstract: Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.

    PROBABILISTIC ENTROPY FOR DETECTION OF PERIODIC SIGNAL ARTIFACTS
    29.
    发明申请
    PROBABILISTIC ENTROPY FOR DETECTION OF PERIODIC SIGNAL ARTIFACTS 审中-公开

    公开(公告)号：US20200338350A1

    公开(公告)日：2020-10-29

    申请号：US16392129

    申请日：2019-04-23

    Applicant: Medtronic, Inc.

    Inventor： Eric J. Panken ,  Jadin C. Jackson ,  Yizi Xiao ,  Christopher L. Pulliam

    IPC: A61N1/36 ,  A61B5/00 ,  A61B5/0478 ,  A61N1/372 ,  A61N1/05

    Abstract: Techniques are disclosed for using probabilistic entropy to select electrodes with fewer artifacts for controlling adaptive electrical neurostimulation. In one example, a plurality of electrodes sense bioelectrical signals of a brain of a patient. Processing circuitry determines, for each bioelectrical signal sensed at a respective electrode of the plurality of electrodes, a probabilistic entropy value of the bioelectrical signal. The processing circuitry compares each of the respective probabilistic entropy values of the bioelectrical signal to respective entropy threshold values and selects, based on the comparisons, a subset of electrodes of the plurality of electrodes. The processing circuitry controls, based on the bioelectrical signals sensed via respective electrodes of the subset of electrodes and excluding the bioelectrical signals of the plurality of bioelectrical signals sensed via respective electrodes not in the subset of electrodes, delivery of electrical stimulation therapy to the patient.

    Patient directed therapy control
    30.
    发明授权
    Patient directed therapy control 有权

    公开(公告)号：US10258798B2

    公开(公告)日：2019-04-16

    申请号：US15012646

    申请日：2016-02-01

    Applicant: Medtronic, Inc.

    Inventor： Eric J. Panken ,  Timothy J. Denison ,  Gregory F. Molnar

    IPC: A61N1/36 ,  A61B5/00 ,  A61M5/142 ,  A61M5/172 ,  A61N1/372 ,  G06F3/01 ,  A61B5/048

    Abstract: A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.

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