Poorly water-soluble drug-containing solid formulation
    23.
    发明申请
    Poorly water-soluble drug-containing solid formulation 审中-公开
    水溶性较差的含药固体制剂

    公开(公告)号:US20070196484A1

    公开(公告)日:2007-08-23

    申请号:US10592122

    申请日:2005-03-09

    IPC分类号: A61K9/24 A61K31/255

    摘要: Even when being released in a region from a lower small intestine to a large intestine with various coatings, bisacodyl is inadequately effective because of its hardness to dissolve due to its poor solubility, and thus a more drug should be contained. In the related art, there have been no techniques for allowing bisacodyl and dioctyl sodium sulfosuccinate to be simultaneously released in a region from a lower small intestine to a large intestine. A solid formulation having a core particle containing bisacodyl and dioctyl sodium sulfosuccinate coated with an enteric coating which allows the drugs to be released in a region from a lower small intestine to a large intestine can be used as an excellent pharmaceutical product.

    摘要翻译: 即使在从较低的小肠到具有各种涂层的大肠的区域中释放时,由于其难溶性,因为其硬度溶解,因此应该含有更多的药物。 在现有技术中,没有任何技术允许在从较小的小肠到大肠的区域中同时释放磺酰基琥珀酸二辛酸钠和二辛基钠。 作为优异的药物,可以使用含有包含比基酸和核心颗粒的核心颗粒,其中包含使肠溶衣涂覆有肠溶衣的二辛基和二辛基磺基琥珀酸钠,其允许药物从低层小肠到大肠的区域中释放。

    Starter motor having intermediate gear

    公开(公告)号:US06647812B2

    公开(公告)日:2003-11-18

    申请号:US09977682

    申请日:2001-10-16

    IPC分类号: F02N1506

    摘要: A starter motor includes an intermediate gear engaging with and driven by a pinion connected to an output shaft of an electrical motor. The intermediate gear is coupled to the pinion by means of a retainer to be shifted in its axial direction together with the pinion. The intermediate gear engages with a ring gear of an engine to crank up the engine when it is shifted in the axial direction. The retainer is connected to a pinion boss by forcibly enlarging a resilient opening of its groove, and the resilient opening recovers its original position after the retainer is connected to the pinion boss. In this manner, the retainer is prevented from dropping off from the pinion boss during an assembling process of the starter motor. The retainer is made of resin to have an enough thickness to secure a sufficient mechanical strength.

    Emission angle variable flash apparatus
    26.
    发明授权
    Emission angle variable flash apparatus 失效
    发射角可变闪光装置

    公开(公告)号:US5734934A

    公开(公告)日:1998-03-31

    申请号:US714418

    申请日:1996-09-16

    CPC分类号: G03B15/05 G03B2215/0528

    摘要: An emission angle variable flash apparatus of the invention alters an angular aperture to be formed by side reflection plates disposed oppositely to both side surfaces of a reflector in linkage with a change of a distance between a Xe tube and a reflector on their optical axis, thereby enhancing the efficiency of utilization of flash from a light source and expanding a variable range of an emission angle in the horizontal direction. As a result, the emission angle variable flash apparatus of the invention is made smaller in size than in the prior art.

    摘要翻译: 本发明的发射角可变闪光装置改变由与反射器的两个侧表面相对设置的侧反射板形成的角孔,其与Xe管和反射器在它们的光轴上的距离的变化相关联,由此 提高闪光灯从光源的使用效率,并扩大水平方向上的发射角度的可变范围。 结果,本发明的发射角可变闪光装置的尺寸比现有技术的尺寸更小。

    Phenolic resin and method for preparing same
    28.
    发明授权
    Phenolic resin and method for preparing same 失效
    酚醛树脂及其制备方法

    公开(公告)号:US5319063A

    公开(公告)日:1994-06-07

    申请号:US5376

    申请日:1993-01-15

    CPC分类号: C08G61/02

    摘要: A phenolic resin can be obtained by a condensation reaction between a specific trifunctional aromatic compound and a phenolic compound. This resin can be reacted with a curing agent such as a hexamine to give cured articles having excellent heat resistance, electrical properties, wear resistance and chemical resistance, and the phenolic resin is also much more excellent in curing reactivity as compared with conventional techniques.

    摘要翻译: 可以通过特定的三官能芳族化合物和酚类化合物之间的缩合反应获得酚醛树脂。 该树脂可以与诸如六胺的固化剂反应,得到耐热性,电性能,耐磨性和耐化学性优异的固化物,与常规技术相比,酚醛树脂的固化反应性也更优异。

    TABLET MANUFACTURING METHOD
    30.
    发明申请

    公开(公告)号:US20120319328A1

    公开(公告)日:2012-12-20

    申请号:US13582395

    申请日:2011-03-03

    IPC分类号: B29C43/02

    CPC分类号: A61J3/10 B30B11/02 B30B15/022

    摘要: An object is to provide a tablet manufacturing method which may restrain formation of a tablet edge surface and permits less effect of intra-tablet stress developed in process of press-forming on a tablet quality in cases where an upper rod and a lower rod are fittingly inserted into a vertical hole formed in a die to press powder in the die hole with a pushing surface at the lower end of the upper rod and a pushing surface at the upper end of the lower rod in order to press-form a tablet.Disclosed is a tablet manufacturing method in which an upper rod 3 and a lower rod 4 are fittingly inserted into a vertical hole 2 formed in a die 1 to press powder 5 in the die hole 2 with a pushing surface 9a at the lower end of the upper rod 3 and a pushing surface 11a at the upper end of the lower rod 4 in order to press-form a tablet 6, characterized in that concave forming grooves 2a integrally linked to the upper and lower pushing surfaces 9a and 11a are formed annularly in the inner circumferential surface of the die hole 2, and the die may be divided into an upper separable piece 7 and a lower separable piece 8 at the bottom portions of the forming grooves 2a, wherein after a final fixed rod or one of the upper and lower rods 3 and 4 is moved to and then fixed at a press-forming position at which the pushing surface 9a or 11a is integrally linked to the corresponding forming groove 2a, a final pressing rod or the other rod 3 or 4 is moved to the press-forming position so that the tablet 6 of a circular, elliptical or oval form as viewed in cross sectional side is press-formed, and then, the press-formed tablet 6 held in the forming grooves 2a is taken out of the die by separating the upper and lower separable pieces 7 and 8, in which case, the tablet 6 after being taken out of a final fixed separable piece or the separable piece 7 or 8 adjacent to the final fixed rod and also out of the final fixed rod is taken out of a final pressing separable piece or the separable piece 7 or 8 adjacent to the final pressing rod.