公开(公告)号：US20120101571A1

公开(公告)日：2012-04-26

申请号：US13130180

申请日：2009-11-20

申请人： Suku Thambar ,  Martin Christopher Cook ,  Stefan Schreck ,  Stayajit Rohan Jayasinghe

发明人： Suku Thambar ,  Martin Christopher Cook ,  Stefan Schreck ,  Stayajit Rohan Jayasinghe

IPC分类号： A61F2/24

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/0061 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2457 ,  A61F2002/8486 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/006

摘要： A heart valve prosthesis (100) comprises a housing component (110) and a valve component (130). The housing component (110) comprises a housing body (111) having a housing passage (112) extending therethrough. The housing body (111) is configured to be located in, or adjacent to and communicating with, a native valve orifice (16) of a heart (10) and to engage structure of the heart (10) to fix the housing body (111) in relation to the valve orifice (161). The housing component (111) is collapsible for delivery via catheter (2). The valve component (130) comprises a valve body (131) having a valve passage (132) extending therethrough. The valve body (131) is configured to be fixed within the housing passage (112) with the valve passage (132) extending along the housing passage (112). One or more flexible valve elements (131) is/are secured to the valve body and extend across the valve passage (132) for blocking blood flow in a first direction through the valve passage (132) whilst allowing blood flow in the opposing direction. The valve component (130) is collapsible for delivery via catheter (2) separate to the housing component (110). An associated method of replacing a failed or failing heart valve utilising the heart valve prosthesis (100) is also disclosed.

摘要翻译： 心脏瓣膜假体（100）包括壳体部件（110）和阀部件（130）。 壳体部件（110）包括具有延伸穿过其的壳体通道（112）的壳体（111）。 壳体（111）构造成位于心脏（10）的天然瓣膜（16）中或邻近并连通，并与心脏（10）的结构接合以固定壳体（111） ）相对于阀孔（161）。 壳体部件（111）可折叠以便经由导管（2）输送。 阀部件（130）包括具有延伸穿过其中的阀通道（132）的阀体（131）。 阀体（131）构造成固定在壳体通道（112）内，阀通道（132）沿壳体通道（112）延伸。 一个或多个柔性阀元件（131）被固定到阀体并延伸穿过阀通道（132），用于阻止通过阀通道（132）的第一方向的血流，同时允许血液沿相反方向流动。 阀部件（130）可折叠以便通过分离到壳体部件（110）的导管（2）输送。 还公开了利用心脏瓣膜假体（100）代替故障或故障心脏瓣膜的相关方法。

公开(公告)号：US20110093063A1

公开(公告)日：2011-04-21

申请号：US12907811

申请日：2010-10-19

申请人： Stefan Schreck

发明人： Stefan Schreck

IPC分类号： A61F2/24

CPC分类号： A61B17/0469 ,  A61B17/00234 ,  A61B2017/00783 ,  A61B2017/0472 ,  A61F2/2409

摘要： A heart valve and tissue repair device for independently, selectively and sequentially grasping heart valve leaflets and independently, selectively and sequentially applying one or more fasteners thereto is disclosed. The device includes a leaflet engaging tip having one or more graspers capable of individually and sequentially grasping leaflets, and one or more deployable fasteners capable of fastening the leaflets. An actuation system for the device individually and selectively controls the graspers and deploys the one or more fasteners. Vacuum pressure from an external vacuum source can be used to grasp the leaflets via a selector system that controls the actuation system so as to individually and sequentially apply vacuum force to the graspers.

摘要翻译： 公开了一种心脏瓣膜和组织修复装置，用于独立地，选择性地和顺序地抓住心脏瓣膜小叶并且独立地，选择性地并且顺序地施加一个或多个紧固件。 该装置包括具有一个或多个能够单独地和顺序地抓握小叶的抓持器的小叶接合尖端以及能够紧固传单的一个或多个可展开的紧固件。 用于该装置的致动系统单独地和选择性地控制抓紧器并展开一个或多个紧固件。 可以使用来自外部真空源的真空压力通过控制致动系统的选择器系统来抓住传单，以便单独地并且顺序地向抓紧器施加真空力。

公开(公告)号：US20100211165A1

公开(公告)日：2010-08-19

申请号：US12767278

申请日：2010-04-26

申请人： Stefan Schreck

发明人： Stefan Schreck

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0075 ,  Y10S623/90

摘要： Expandable prosthetic heart valves for minimally invasive valve replacement are disclosed. In one preferred embodiment, an expandable prosthetic heart valve includes a support stent comprising an expandable tubular base along an inflow end and three upstanding commissure posts along an outflow end. The three commissure posts are spaced at 120 degree intervals with gaps therebetween. The prosthetic heart valve further includes a tubular flexible member having a prosthetic section and a fabric section. The prosthetic section is connected to the three commissure posts and defines three leaflets, preferably formed of pericardial tissue. The fabric section is sutured to the expandable tubular base. The tubular base may be formed with a shape memory material and is sized for deployment with an annulus of a native aortic valve. After deployment, the three commissure posts support the leaflets above the tubular base for replacing the function of the native aortic valve. In one variation, flanges may be provided on the support stent for improving attachment of the support stent to the host tissue.

摘要翻译： 公开了用于微创瓣膜置换的可扩展的假体心脏瓣膜。 在一个优选实施例中，可扩张假体心脏瓣膜包括支撑支架，其包括沿着流入端的可膨胀管状基部和沿流出端的三个直立连合柱。 三个连合柱以120度间隔隔开间隙。 假体心脏瓣膜还包括具有假体部分和织物部分的管状柔性部件。 修复部分连接到三个连合柱并且限定三个小叶，优选由心包组成。 将织物部分缝合到可扩张的管状基部。 管状基底可以形成有形状记忆材料，并且其尺寸适于与天然主动脉瓣的环空展开。 部署后，三个连合柱支撑管状基座上方的传单，以更换天然主动脉瓣的功能。 在一个变型中，可以在支撑支架上设置凸缘，以改善支撑支架附着到宿主组织。

公开(公告)号：US20050043791A1

公开(公告)日：2005-02-24

申请号：US10868470

申请日：2004-06-14

申请人： Patrick McCarthy ,  Richard Rhee ,  Stefan Schreck

发明人： Patrick McCarthy ,  Richard Rhee ,  Stefan Schreck

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61F2/2445 ,  A61F2/2466 ,  A61M25/001 ,  A61M25/0032 ,  A61M25/0069 ,  A61M25/007 ,  A61M25/0071 ,  A61M25/0138 ,  A61M2025/0002 ,  A61M2025/0003 ,  A61M2025/0004 ,  A61M2025/0081

摘要： An annuloplasty ring having a three-dimensional discontinuous form generally arranged about an axis with two free ends that are axially offset. The ring is particularly suited for repair of the tricuspid valve, and more closely conforms to the annulus shape. The ring is more flexible in bending about radially extending axes than about the central axis. The ring may have an inner structural support covered by a pliable sleeve and/or a fabric tube. The structural support may have a varying cross-section, such as a C-shaped cross-section in a mid-section between two free ends and a rectangular cross-section at the free ends. A deliver template having a mounting ring with about the same shape as the ring facilitates implant, and may be releasably attached to a delivery handle. The deliver template may include a plurality of cutting guides for releasably attaching the annuloplasty ring thereto while presenting maximum outer surface area of the ring. The template may have an outwardly-facing groove to receive and retain the ring.

公开(公告)号：US06454799B1

公开(公告)日：2002-09-24

申请号：US09549413

申请日：2000-04-06

申请人： Stefan Schreck

发明人： Stefan Schreck

IPC分类号： A61F224

CPC分类号： A61F2/2427 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0075 ,  Y10S623/90

摘要： Expandable heart valves for minimally invasive valve replacement surgeries are disclosed. In a first embodiment, an expandable pre-assembled heart valve includes a plastically-expandable annular base having plurality of upstanding commissure posts. A tubular flexible member including a prosthetic section and a fabric section is provided, with the prosthetic section being connected to the commissure posts and defining leaflets therebetween, and the fabric section being attached to the annular base. In a second embodiment, an expandable heart valve includes an annular tissue-engaging base and a subassembly having an elastic wireform and a plurality of leaflets connected thereto. The annular base and subassembly are separately stored and connected just prior to delivery to the host annulus. Preferably, the leaflet subassembly is stored in its relaxed configuration to avoid deformation of the leaflets. The expandable heart valves may be implanted using a balloon catheter. Preferably, the leaflets of the heart valves are secured to the commissure regions of the expandable stents using a clamping arrangement to reduce stress.

摘要翻译： 公开了用于微创瓣膜置换手术的可扩张心脏瓣膜。 在第一实施例中，可扩张预组装心脏瓣膜包括具有多个直立连合柱的塑性扩张的环形基座。 提供了一种包括假体部分和织物部分的管状柔性部件，其中假体部分连接到连合柱并在其间限定传单，并且织物部分附接到环形基部。 在第二实施例中，可扩张心脏瓣膜包括环形组织接合基座和具有弹性线形和与其连接的多个传单的子组件。 环形基座和子组件在传送到主机环之前分开储存和连接。 优选地，小叶组件以其松弛构型存储以避免传单变形。 可以使用球囊导管植入可扩张心脏瓣膜。 优选地，使用夹紧装置将心脏瓣膜的小叶固定到可扩张支架的连合区域以减轻压力。

公开(公告)号：US09700701B2

公开(公告)日：2017-07-11

申请号：US13544426

申请日：2012-07-09

申请人： Joshua Benjamin ,  Stefan Schreck

发明人： Joshua Benjamin ,  Stefan Schreck

IPC分类号： A61F2/06 ,  A61M25/06 ,  A61F2/95 ,  A61M25/00 ,  A61F2/966

CPC分类号： A61M25/0662 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M25/0097 ,  A61M2025/0006 ,  A61M2025/0079 ,  A61M2025/0681

摘要： Some embodiments are directed to a catheter system comprising an introducer having a main body, an introducer sheath projecting from the main body, and a first seal supported within the introducer and a catheter having a main body, an outer sheath projecting from the main body, a second seal supported within the catheter, and an inner core configured to be advanced axially through the main body, the second seal, and the outer sheath. The introducer can be configured to be selectively engageable with the catheter so that the catheter can be selectively and removably linked with the introducer in the axial direction. The catheter system can also be configured such that, when the introducer and the catheter are linked, the catheter can be rotatable relative to the introducer. The introducer can be configured to radially restrain an endoluminal prosthesis.

公开(公告)号：US20120259406A1

公开(公告)日：2012-10-11

申请号：US13441762

申请日：2012-04-06

申请人： Stefan Schreck ,  Jason Fox

发明人： Stefan Schreck ,  Jason Fox

IPC分类号： A61F2/82

CPC分类号： A61B17/12036 ,  A61B6/481 ,  A61B6/504 ,  A61B17/12118 ,  A61B17/12136 ,  A61B17/12186 ,  A61B2017/00659 ,  A61B2017/1205 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2230/0034 ,  A61M25/09 ,  A61M25/1018 ,  A61M25/104

摘要： Methods for treatment of aneurysms using a sequential manifold console to deploy multiple filling structures are provided herein. In one aspect, aneurysms are treated by simultaneously filling two double-walled filling structure using a sequential manifold console to guide a user in the steps to be followed in the procedure and to reliably achieve a consistent and durable aneurysmal treatment using a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Pairs of filling structures delivered to the aneurysm from different access openings of a patient can be simultaneously prepared and pressurized from a single treatment console when treating abdominal aortic aneurysms using the described systems and methods.

摘要翻译： 本文提供了使用顺序歧管控制台来部署多个填充结构来治疗动脉瘤的方法。 在一个方面，通过使用顺序的歧管控制台同时填充两个双壁填充结构来治疗动脉瘤，以引导使用者在该过程中要遵循的步骤中，并且使用可固化介质可靠地实现一致且持久的动脉瘤治疗。 结构可以在气囊展开机构上传送，以便通过其形成和打开管状流明。 使用所述系统和方法治疗腹主动脉瘤时，可以从单个治疗控制台同时制备并从患者的不同进入口输送到动脉瘤的一对填充结构。

公开(公告)号：US20120165917A1

公开(公告)日：2012-06-28

申请号：US13397952

申请日：2012-02-16

申请人： Stefan Schreck ,  Daniel Hawkins

发明人： Stefan Schreck ,  Daniel Hawkins

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2250/0024

摘要： Some embodiments are directed to a stent graft comprising a first stent graft having a first and a second stent and a first and a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.

摘要翻译： 一些实施例涉及包括具有第一和第二支架的第一支架移植物和由第一支架支撑的第一和第二内部移植物以及外部移植物的支架移植物。 第二内部移植物可以与第一内部移植物间隔开，使得第一支架的一部分不被第一内部移植物或第二内部移植物覆盖。 外部移植物的第一和第二部分可以附接到第一支架，外部移植物在第一和第二部分之间不被支架支撑，以便在外部移植物，第一内部移植物和第二部分之间形成可填充的空间 第二内移植物。 一些实施例还包括可展开在第一支架移植物内部的第二支架移植物，以密封地覆盖第一支架的未覆盖部分。

公开(公告)号：US20090105806A1

公开(公告)日：2009-04-23

申请号：US12257149

申请日：2008-10-23

申请人： Joshua Benjamin ,  Stefan Schreck

发明人： Joshua Benjamin ,  Stefan Schreck

IPC分类号： A61F2/06

CPC分类号： A61F2/92 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2250/0039

摘要： A tubular prosthesis can be formed by rolling a sheet of material about a longitudinal axis, thereby forming a plurality of annular rings that can be arranged so as to be longitudinally adjacent one another, thus forming a tubular prosthesis. Each annular member can expand and contract independent of the other annular members. A graft material can extend between the plurality of annular members.

摘要翻译： 可以通过围绕纵向轴线滚动一块材料来形成管状假体，从而形成多个可以被布置为彼此纵向相邻的环形环，从而形成管状假体。 每个环形构件可独立于其它环形构件而膨胀和收缩。 移植物材料可以在多个环形构件之间延伸。

公开(公告)号：US20080071343A1

公开(公告)日：2008-03-20

申请号：US11522292

申请日：2006-09-15

申请人： Kevin John Mayberry ,  Trinh Van Pham ,  Brian Christopher Gray ,  Stefan Schreck

发明人： Kevin John Mayberry ,  Trinh Van Pham ,  Brian Christopher Gray ,  Stefan Schreck

IPC分类号： A61F2/06

CPC分类号： A61F2/962 ,  A61F2/954 ,  A61F2002/065 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9522

摘要： A deployment catheter for deploying endoluminal vascular prosthesis that has at least a main graft portion and a first branch graft portion includes an elongate, flexible catheter body having a proximal end and a distal end and comprising an outer sheath and an inner core that is axially moveable with respect to the outer sheath. The catheter includes a main graft restraint that has a main graft release mechanism comprising a plurality of axially spaced restraint members. The catheter further includes a branch graft restraint comprising a branch graft release mechanism.

摘要翻译： 用于部署具有至少主移植部分和第一分支移植部分的腔内血管假体的展开导管包括细长的柔性导管主体，其具有近端和远端，并且包括外护套和可轴向移动的内芯 相对于外护套。 导管包括主移植物约束装置，其具有包括多个轴向间隔开的约束构件的主移植物释放机构。 导管还包括分支移植物约束装置，其包括分支移植物释放机构。