公开(公告)号：USD962260S1

公开(公告)日：2022-08-30

申请号：US29758171

申请日：2020-11-12

Applicant: Sigma-Aldrich Co. LLC ,  EMD Millipore Corporation

Designer： Sarah Trice ,  Lindsey Rickershauser ,  Xiang Wu ,  Churl Oh ,  Nadia Brugger ,  Emma Gardener

公开(公告)号：US20220186841A1

公开(公告)日：2022-06-16

申请号：US17438244

申请日：2020-06-17

Applicant: EMD MILLIPORE CORPORATION

Inventor： Brian Pereira

IPC: F16K3/26 ,  F16K27/04

Abstract: A valve having a body having a first section and a second section; an extended flange attached to the second section of the body or disposed as an integral part of the second section of the body; an elongate bore extending through the body and having a proximal end and a distal end; a longitudinally displaceable plunger disposed in and extending along the bore, the plunger having a proximal end and a distal end and having a first position displaced toward the distal end of the bore and a second position displaced toward the proximal end of the bore; a diaphragm seal attached to the proximal end of the plunger and sealing the bore at the proximal end thereof; a gland seal sealing the bore at a location intermediate the diaphragm seal and the distal end of the bore; the plunger extending through and being sealingly secured to the gland seal; a fluid transfer opening in the bore between the diaphragm seal and the gland seal; longitudinal displacement of the plunger moving the diaphragm seal to open the bore, the gland seal stretching to accommodate the displacement of and maintain a seal about the plunger, a fluid flow path being established between the open proximal end of the bore and the fluid transfer opening, wherein longitudinal displacement of the plunger towards its first position moves the diaphragm to open the bore. The valve further comprises an extended flange having a surface that is approximately coplanar with a surface of the second position when the plunger is displaced toward the proximal end of the bore, creating a zero dead leg position

公开(公告)号：US20220184599A1

公开(公告)日：2022-06-16

申请号：US17609008

申请日：2020-08-06

Applicant: EMD MILLIPORE CORPORATION

Inventor： Martin Morrissey ,  Conor King ,  Philip Borozenets

IPC: B01L1/04 ,  B25J21/00 ,  B25J21/02

Abstract: An apparatus for use with an isolator, including a crown for releasably joining with a beta port of the isolator, wherein the crown includes at least one anchoring support; a spring hook on at least one end of the at least one anchoring support; a needle block including at least one through hole for having a needle positioned therein, wherein the at least one needle is joined with tubing; a yoke; and a biasing element releasably joined with the yoke and the at least one anchoring support; wherein the needle block is releasably joined to the crown.

公开(公告)号：US11358102B2

公开(公告)日：2022-06-14

申请号：US16918431

申请日：2020-07-01

Applicant: EMD Millipore Corporation

Inventor： Jad Jaber ,  Wilson Moya ,  Mikhail Kozlov

IPC: B01D61/14 ,  B01D67/00 ,  B01D69/12 ,  B01D69/02 ,  B01D69/10 ,  B01D71/08

Abstract: The embodiments described herein relate to agarose ultrafiltration membrane composites and methods for making and using the same.

公开(公告)号：US20220148686A1

公开(公告)日：2022-05-12

申请号：US16772293

申请日：2019-07-30

Applicant: EMD Millipore Corporation ,  Sigma-Aldrich Co. LLC

Inventor： Sarah Trice ,  Tim Knehans ,  Maciej Wojcikowski

IPC: G16C60/00 ,  G16C20/90 ,  G06F21/62 ,  G06F21/60

Abstract: A system, software application and method that allows a customer to protect their proprietary database of compounds and substances while utilizing a retrosynthesis software application is disclosed. The customer's proprietary database is encrypted prior to being provided to the retrosynthesis system. This encrypted is performed using a hash and optionally a salt. The retrosynthesis algorithm then creates synthons as is traditionally done. However, after their creation, the synthons are hashed so that they may be compared to the entries in the customer's proprietary database. In this way, the actual contents of the customer's database are never made available to the retrosynthesis system or software application.

公开(公告)号：US11179677B2

公开(公告)日：2021-11-23

申请号：US15562171

申请日：2016-06-01

Applicant: EMD Millipore Corporation

Inventor： Brian Hillier

IPC: B01D61/10 ,  B01D65/00 ,  B01D61/08 ,  B01D63/08

Abstract: A sealing case for a filtration cassette that reliably prevents leaks after assembly and installation into a filtration system. The sealing case fits on the filtration cassette and provides a fluid-tight seal between the sealing case and around at least one port in the filtration cassette when installed in a filtration system. The sealing case may comprise two halves that mate together, and each half may be identical. The internal surface of the sealing case is flat or substantially flat.

公开(公告)号：US20210355427A1

公开(公告)日：2021-11-18

申请号：US17312960

申请日：2020-03-26

Applicant: EMD MILLIPORE CORPORATION

Inventor： Anne Hansen ,  Kevin O'Brien ,  Amy Wood ,  Noah Rhein ,  Thomas Janko ,  Oliver Hiller

IPC: C12M1/36 ,  C12M1/34

Abstract: A system for processing a biological fluid that includes a bioreactor, wherein the bioreactor includes a window, at least one port for allowing delivery of a processing aid; a control system, a sensor; a transmitter for transmitting the signal; a signal converter; a controller for receiving the signal; and a valve for delivering the processing aid to the port, wherein the sensor senses a process condition, transmits the signal, and the signal is compared with a reference signal and wherein a process action is optionally taken based on the comparison.

公开(公告)号：US20210339939A1

公开(公告)日：2021-11-04

申请号：US17377606

申请日：2021-07-16

Applicant: EMD Millipore Corporation

Inventor： John Gugliotti ,  Michael Gugliotti

IPC: B65D85/24 ,  B65D33/16 ,  A61M5/32

Abstract: A needle protector, having a flexible material, a pocket defining an internal volume, a wrapping strap having a plurality of holes, and a main body disposed between the pocket and the wrapping strap; at least one rigid body or cylinder for placement within the internal volume; and; a pin for placement within one of the plurality of holes, wherein the pin is capable of releasably locking the pocket and the main body when the wrapping strap is wrapped around the pocket and the main body.

公开(公告)号：US20210322901A1

公开(公告)日：2021-10-21

申请号：US17262356

申请日：2019-08-12

Applicant: EMD Millipore Corporation

Inventor： Michael James Susienka ,  Jeremy Perreault ,  Joseph Geringer ,  Brian Hillier ,  Joseph Muldoon ,  John Paul Amara

IPC: B01D27/14 ,  B01D35/30 ,  B01D63/08

Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.

公开(公告)号：US20210299614A1

公开(公告)日：2021-09-30

申请号：US16328502

申请日：2017-10-05

Applicant: EMD Millipore Corporation

Inventor： Christopher A. Scott ,  Kurt Greenizen ,  Paul Sydlowski

IPC: B01D63/08 ,  B01D61/18 ,  B01D61/20

Abstract: A funnel-less filtration device that attaches directly to a storage container such as a cell culture media bottle. The device includes a filter collar containing one or more membranes, an inlet with a coupling device for attaching the filter device to a supply of liquid to be filtered, an outlet at a lower portion of the collar, a vacuum port in the collar below the membrane(s) and a filtered vent in the collar above the membrane(s). Optionally, the device may include a filtrate reservoir attached to the outlet, preferably by a threaded connection. Optionally, the upper opening to the filter collar is selectively and removably sealed with a lid until used. The lid is then removed the filter device inverted over a storage container such as cell culture media bottle and the two are attached via the upper opening of the filter collar. The assembly is then inverted so the supply container is above the filter device. Upon subjecting the sample in the bottle to a driving force such as vacuum, the sample flows through the filtration element, and into a filtrate reservoir below the outlet of the filter collar.