摘要:
The present invention discloses a hypocrellin derivative substituted both in a pen-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d: The hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino prepared in the present invention has a maximum absorption wavelength of 600-650 nm and a molar extinction coefficient reaching about 20000-40000 M−1cm−1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition. In the same condition, the hypocrellin derivative substituted both in a pen-position and in a 2-position by an amino involved in the present invention, when used as a photosensitizer, has a stronger ability to photo-dynamically inactivate tumor cells than the first and second generation commercial photosensitizers.
摘要:
The present invention provides methods of processing lipid materials such as soapstock, wet gums and dry gums. Enzymes are utilized to catalyze hydrolysis of the lipids materials to recover fatty acids. Addition of organic acids and/or polyols improved yield of fatty acids and reduced formation of emulsion. Lipid materials can be formulated with other agricultural products as new value-added animal feed products. Further, a process for concentrating nitrogenous compounds such as choline, inositol, ethanolamine and serine from phospholipid materials obtained as byproducts from vegetable oil refining is provided. The process involves performing hydrolysis of the gum based products in the presence of an alcoholic solvent and acid catalyst. Post hydrolysis, gums breakdown to oil and water phases which are further separated and concentrated. These concentrated products may be further fractionated to concentrate individual nitrogenous compounds.
摘要:
A control device performs control of a culture condition in production of an organic compound by a fermentation method. The control device executes processing a plurality of times to acquire culture data, to calculate, using the acquired culture data, a plurality of candidates for a culture condition set in advance, and a linear model set in advance that outputs a production amount of an organic compound at a future time, the production amount at the future time for each of the candidates, to determine an optimum candidate out of the candidates using the calculated production amount at the future time for each of the candidates and a target production amount of the organic compound at the future time set in advance, and to change the culture condition to the determined candidate. The linear model and the target production amount are set for each time.
摘要:
A process for converting tryptophan into kynurenine. The conversion of tryptophan into kynurenine is carried out by irradiating a substance comprising tryptophan with electromagnetic radiation comprising waves with wavelength in the range of 10 nanometer to 750 nanometer.
摘要:
A method of killing pathogenic fungi by contacting them with an effective amount of (1R,2S)-2-aminocyclopentanecarboxylic acid (FR109615) or a salt thereof.
摘要:
The invention provides a protein hydrolysate with(a) a content of NaC1 between 0 and 35% w/w;(b) a content of free amino acids between 25 and 100% w/w; and(c) a content of glutamic acid between 8 and 60% (w/w calculated as dry matter)and optionally from 0-75% by weight of the hydrolysate of a saccharide carrier. Such a hydrolysate is obtainable by gel filtration over a porous material having an average pore diameter between 0.5 and 2.5 nanometers and eluting the desired fraction.
摘要:
The invention relates to salts of 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazine (HOObt) and compounds containing a primary amino group, a process for their preparation and their use.
摘要:
A process for purifying lysine in a lysine production process, which involves passing a solution containing lysine over a cation exchange resin such that lysine adsorbs onto the resin, eluting adsorbed lysine from the resin with an aqueous solution of ammonia to produce a lysine-containing elution liquid, passing the elution liquid directly to a reverse osmosis membrane system, and concentrating the lysine-containing elution liquid with the reverse osmosis membrane system such that ammonia is selectively removed from the lysine containing elution; the aqueous ammonia which is separated from the lysine may be recycled through the cation exchange resin to regenerate the resin or to elute more lysine from the resin.
摘要:
A process for refining phenylalanine, in which a phenylalanine solution containing tyrosine as the main impurity and other impurities is contacted with a non-polar, highly porous synthetic adsorbent, adsorbing phenylalanine on the adsorbent selectively, and eluting and recovering the adsorbed phenylalanine, is disclosed.