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    Culture slide assembly
    22.
    发明授权
    Culture slide assembly 失效
    文化滑梯组装

    公开(公告)号：US5605813A

    公开(公告)日：1997-02-25

    申请号：US468786

    申请日：1995-06-06

    Applicant: Timothy A. Stevens ,  Tadeusz A. Tyndorf

    Inventor： Timothy A. Stevens ,  Tadeusz A. Tyndorf

    IPC: G01N1/00 ,  C12M1/00 ,  C12M1/24 ,  C12M1/34 ,  C12M3/00 ,  G01N1/28 ,  C12Q1/08

    CPC classification number: C12M23/08 ,  C12M25/06 ,  C12M41/36

    Abstract: The present invention is a culture slide assembly having a base member, a cooperable receptacle chamber removably attached to the base and means for separating the chamber from the base. Preferably, the assembly may be used for carrying out biological reactions or growth therein, such as growing tissue or cell cultures.

    Abstract translation: 本发明是一种培养用滑动组件，其具有基部构件，可拆卸地连接到基座的可配合的容器室以及用于将腔室与基部分离的装置。 优选地，组合物可以用于在其中进行生物反应或生长，例如生长组织或细胞培养物。

    Method for computing morphology of cornea endothelium cells
    23.
    发明授权
    Method for computing morphology of cornea endothelium cells 失效
    角膜内皮细胞形态学计算方法

    公开(公告)号：US5523213A

    公开(公告)日：1996-06-04

    申请号：US216553

    申请日：1994-03-23

    Applicant: Yoko Takahashi ,  Tatsuya Kasahara

    Inventor： Yoko Takahashi ,  Tatsuya Kasahara

    IPC: A61B3/117 ,  A61B3/10 ,  A61B19/00 ,  A61F9/007 ,  G06T1/00 ,  G06T7/60 ,  C12Q1/02 ,  C12Q1/08 ,  G01B11/26

    CPC classification number: A61F9/00736 ,  A61B90/36

    Abstract: In examining the progress of patients before and after a cataract operation, the morphology of cornea endothelium cells used in medical treatment, may be determined from a cornea endothelium cell image with less labor. Center points of two-dimensionally continuous cells of a cornea endothelium cell image are entered into a computer, and peripheral points obtained by determining peripheral points which are center points of the cells within a specified distance from one center point are sorted clockwise. If an angle formed by successive two peripheral points and the center point is less than a specified angle, the greater of the two peripheral points in distance from the center point is excluded from the peripheral points. If a distance between the first point and the third point of the obtained successive three peripheral points is shorter than a distance between the center point and the second point, the second point is excluded from the peripheral points, and average distances between the peripheral points and the center point are determined. A perpendicular line that proportionally divides a distance between a center point and its peripheral points by their average distances to the peripheral points is determined for each of the successive peripheral points, and intersection points of the resulting perpendicular lines are determined as vertices of the cells. Thus, morphological data are computed from the obtained vertices.

    Abstract translation: 在检查白内障手术前后患者的进展情况下，用于治疗的角膜内皮细胞的形态可以从较少劳动的角膜内皮细胞图像中确定。 将角膜内皮细胞图像的二维连续细胞的中心点输入到计算机中，并且通过确定作为从一个中心点指定距离内的细胞的中心点的周边点获得的外围点顺序排列。 如果由连续的两个周边点和中心点形成的角度小于指定角度，则距离中心点的距离中的两个外围点中的较大者从外围点排除。 如果所获得的连续三个周边点的第一点和第三点之间的距离小于中心点和第二点之间的距离，则将第二点从外围点排除，并且外围点与 确定中心点。 对于每个连续的外围点确定垂直线，其将中心点与其外围点之间的距离成比例地划分为与周边点的平均距离，并且将所得垂直线的交点确定为单元格的顶点。 因此，从获得的顶点计算形态数据。

    Methods and apparatus for spectroscopic identification and/or calibrated quantification of surface concentration of materials
    30.
    发明授权
    Methods and apparatus for spectroscopic identification and/or calibrated quantification of surface concentration of materials 有权

    公开(公告)号：US11525731B1

    公开(公告)日：2022-12-13

    申请号：US17314695

    申请日：2021-05-07

    Applicant: Photon Systems, Inc.

    Inventor： Michael R. Reid

    IPC: G01J3/02 ,  C12Q1/24 ,  G01J3/28 ,  C12Q1/08

    Abstract: Apparatus and methods for creating deposits of uniformly spaced or uniformly overlapping droplets of selected chemicals where each droplet has an a priori known amount of the selected chemical or chemicals is taught (including biological and microbial materials). In some embodiments the deposits may be used as samples of different but known concentrations that may be used to calibrate spectroscopic inspection instruments to enable such instruments to not only provide identification in situ of unknown materials but also to provide calibrated and traceable surface concentrations of such materials. In some embodiments, such calibrated instruments may be used in enhanced processes for validating the cleanliness of manufacturing surfaces such as surfaces of equipment used in the preparation of pharmaceuticals, food, or semiconductor devices. Such instruments may be used to ensure adequate purity, or non-contamination, of surfaces of products themselves or packaging materials or of locations where such products will be used. Such calibrated instruments may also be useful in detecting cleanliness of non-manufacturing surfaces where contamination may be of concern, whether they be public or private spaces such as laboratories, restaurants, airports, satellites or other spacecraft. In some embodiments, such instruments may range from deep UV instruments to far infrared instruments or beyond.

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