-
公开(公告)号：USD853226S1
公开(公告)日：2019-07-09
申请号：US29618352
申请日：2017-09-20
Applicant: EMD Millipore Corporation
Designer： Joseph Geringer , Stephen G. Hunt , Mikhail Kozlov , Joseph Almasian , Gregory Straeffer
-
公开(公告)号：US10322376B2
公开(公告)日：2019-06-18
申请号：US15351538
申请日：2016-11-15
Applicant: EMD Millipore Corporation
Inventor： Kevin Rautio
IPC: B01D61/14 , B01D63/08 , B01D65/00 , B01D69/10 , B01D69/12 , B01D71/34 , B01D71/68 , B29C65/00 , B29C65/18 , B29K27/00 , B29K81/00 , B29L22/00 , B29L31/14 , B29K105/00 , B29K105/04
Abstract: A laminate is provided comprising at least one polysulfone and/or polyethersulfone porous membrane heat bonded to a polyvinylidene fluoride substrate.
-
公开(公告)号：US10272429B2
公开(公告)日：2019-04-30
申请号：US15831976
申请日：2017-12-05
Applicant: EMD Millipore Corporation
Inventor： Terry Gaige , Andrew Zayac , Paul Sydlowski , Philip Lee
Abstract: In one embodiment, a removable pneumatic connector, comprises a body having a plurality of bores passing through, each bore surrounded by a sealing member on an inner surface of the body. A plurality of gas lines may be placed within a corresponding bore. A vacuum port is disposed on the inner surface of the body, and an outer seal on the inner surface of the body surrounds the sealing members and the vacuum port.A vacuum line may be placed within the vacuum port, and configured to deliver negative pressure to the vacuum port. A vacuum holding area is created in the volume between the outer seal and each of the sealing members when the inner surface of the body is placed against a substrate. When the vacuum line is activated, a vacuum is created within the vacuum holding area, creating a positive seal between the body and the substrate.
-
公开(公告)号：US20190111395A1
公开(公告)日：2019-04-18
申请号：US16094237
申请日：2017-04-20
Applicant: EMD Millipore Corporation
Inventor： Kurt E. Greenizen , Christopher A. Scott , Paul Sydlowski , John Doyle , Ryan A. Amara
Abstract: A clamp including a first jaw member having a camming surface, a second jaw member pivotable with respect to the first jaw member, a first biasing member biasing the first and second jaw members to a first position; and a locking mechanism that includes a cam or roller for cooperating with the camming surface of the jaw member, and a second biasing member biasing the cam or roller against the camming surface to lock the first and second jaw members in a second position. An optional alignment collar can be used to align components of the filtration apparatus prior to clamping. Filtration apparatus including the clamp, and also optionally including the alignment collar, is also disclosed.
-
公开(公告)号：US20190099716A1
公开(公告)日：2019-04-04
申请号：US16207874
申请日：2018-12-03
Applicant: EMD Millipore Corporation
Inventor： Herbert Lutz , Joseph Parrella , Bala Raghunath
IPC: B01D61/14
Abstract: The present invention provides, in various embodiments, hybrid single-pass tangential flow filtration assemblies, disposable single-pass tangential flow filtration assemblies, scalable single-pass tangential flow filtration assemblies and adaptable modular single-pass tangential flow filtration assemblies. In other embodiments, the invention relates to processes for recovering proteins from the surface of a filtration membrane in a single-pass tangential flow filtration assembly and for cleaning a tangential flow filtration assembly. In additional embodiments, the invention provides methods of increasing the processing capacity of a single-pass tangential flow filtration assembly.
-
Patent Agency Ranking
公开(公告)号：US10233211B2
公开(公告)日：2019-03-19
申请号：US13955024
申请日：2013-07-31
Applicant: EMD Millipore Corporation
Inventor： Wilson Moya , Jad Jaber
Abstract: The present invention relates to a selectively soluble polymer capable of binding to a desired molecules in an unclarified mixture containing various biological materials and the methods of using such a polymer to purify a molecule from such a mixture. The polymer is soluble in the mixture under a certain set of process conditions such as pH or temperature and/or salt concentration and is rendered insoluble and precipitates out of solution upon a change in the process conditions. The polymer is capable of binding to the desired molecule (protein, polypeptide, etc) and remains capable of binding to that molecule even after the polymer is precipitated out of solution. The precipitate can then be filtered out from the remainder of the stream and the desired biomolecule is recovered such as by elution and further processed.
-
公开(公告)号：US20180362595A1
公开(公告)日：2018-12-20
申请号：US16113403
申请日：2018-08-27
Applicant: EMD Millipore Corporation
Inventor： Nanying Bian , Neil Soice , Shari Spector , Kara Levine
IPC: C07K14/31 , B01J20/32 , B01D15/38 , B01J20/286
Abstract: The present invention relates to chromatography ligands having improved caustic stability, e.g., ligands based on immunoglobulin-binding proteins such as, Staphylococcal protein A, as well as methods of making and using such ligands.
-
公开(公告)号：US10151679B2
公开(公告)日：2018-12-11
申请号：US15057641
申请日：2016-03-01
Applicant: EMD Millipore Corporation
Inventor： Salvatore Giglia , David Nhiem , Gabriel Tkacik
Abstract: A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 μm in diameter, and even as small as 2 μm in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at least one or more of the particles in the stream will penetrate a defective region or regions within the membrane but will not penetrate in the integral region of the membrane. Wetting of the filter is not required.
-
公开(公告)号：US20180345173A1
公开(公告)日：2018-12-06
申请号：US16058258
申请日：2018-08-08
Applicant: EMD Millipore Corporation
Inventor： Nripen Singh , Kwok-Shun Cheng
Abstract: A process for the primary clarification of feeds, including chemically treated flocculated feeds, containing the target biomolecules of interest such as mAbs, mammalian cell cultures, or bacterial cell cultures, using a primary clarification depth filtration device without the use of a primary clarification centrifugation step or a primary clarification tangential flow microfiltration step. The primary clarification depth filtration device contains a porous depth filter having graded porous layers of varying pore ratings. The primary clarification depth filtration device filters fluid feeds, including chemically treated flocculated feeds containing flocculated cellular debris and colloidal particulates having a particle size distribution of approximately about 0.5 μm to 200 μm, at a flow rate of about 10 litres/m2/hr to about 100 litres/m2/hr. Kits and methods of using and making the same are also provided.
-
公开(公告)号：US10088398B2
公开(公告)日：2018-10-02
申请号：US14994402
申请日：2016-01-13
Applicant: EMD Millipore Corporation
Inventor： Phillip Clark , Kurt Greenizen , John Doyle
Abstract: Fluid containment pressure vessel that eliminates the outer support housing present in certain conventional vessels, and provides an improved cap-to-body interface. In certain embodiments, the cap is threaded and configured to threadingly engage with the body of the pressure vessel, and has sufficient structural integrity to withstand the pressures in the device without the need for a support housing. In certain embodiments, an interlock mechanism is provided that prevents the cap from being opened (e.g., removed from the body) while the device is under pressure. In certain embodiments, a pressure relief valve is provided with a pre-loaded biasing mechanism to achieve the required pressure release rate. The vessel can be used for sample preparation, including purification or concentration of samples, particularly protein samples.
-
-
-
-
-
-
-
-
-
Search Results
488
records
(took 0.044 seconds)
