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公开(公告)号：US20150321018A1
公开(公告)日：2015-11-12
申请号：US14801211
申请日：2015-07-16
发明人： Kellie Fletcher , Patrick Hard , Anthony V. Caparso , Karen Tsuei
CPC分类号： A61N1/36075 , A61N1/0526 , A61N1/0529 , A61N1/0558 , A61N1/36071 , A61N1/36132 , A61N1/37235 , A61N1/37241 , A61N1/37247 , A61N1/37264 , A61N1/37282 , A61N1/375 , A61N1/3787
摘要： An apparatus (10) for applying stimulation therapy to a patient includes an implantable medical device (20) and a remote controller (50) for inductively powering the medical device and communicating with the medical device. The remote controller (50) includes a feedback portion (220) for helping to establish a communication link between the remote controller and the implantable medical device (20).
摘要翻译： 用于对患者施加刺激治疗的装置（10）包括可植入医疗装置（20）和用于对医疗装置进行感应供电并与医疗装置通信的遥控器（50）。 遥控器（50）包括用于帮助建立遥控器和可植入医疗装置（20）之间的通信链路的反馈部分（220）。
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32.发明申请公开(公告)号：US20140276195A1
公开(公告)日：2014-09-18
申请号：US14205784
申请日：2014-03-12
CPC分类号： A61B5/4836 , A61B5/04001 , A61B5/0484 , A61B5/4893 , A61N1/08
摘要： Methods for intra-operatively monitoring nerve evoked potentials such as somatosensory nerve evoked potentials during a surgical procedure. The methods include orthrodromic and antidromic monitoring of nerve evoked potentials. Monitoring includes navigating the surgical pathway to avoid insult to anatomical tissue, minimizing activation of sensory nerves that result in undesirable side effects in a patient, and determining the suitable location for placement of an implantable medical device.
摘要翻译： 手术中监测手术过程中神经诱发电位（如体感神经诱发电位）的方法。 这些方法包括神经诱发电位的orthrodromic和antidromic监测。 监测包括导航外科手术途径以避免侮辱解剖组织，最小化感觉神经的活动，导致患者中不期望的副作用，以及确定用于放置可植入医疗装置的合适位置。
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33.发明申请公开(公告)号：US20140155956A1
公开(公告)日：2014-06-05
申请号：US14093094
申请日：2013-11-29
发明人： Benjamin D. Pless , Shannon Schuetz
IPC分类号： A61N1/36
CPC分类号： A61N1/3606 , A61N1/36157 , A61N1/36171 , A61N1/36175
摘要： One aspect of the present disclosure relates to a method for treating a menopause-related condition in a subject. One step of the method can include inserting a therapy delivery device into a vessel of the subject. Next, the therapy delivery device can be advanced to a point substantially adjacent a target site of the sympathetic nervous system (SNS) that is associated with the menopause-related condition. The therapy delivery device can then be activated to deliver a therapy signal to the target site of the SNS in an amount and for a time sufficient to effect a change in sympathetic activity in the subject and thereby treat the menopause-related condition.
摘要翻译： 本公开的一个方面涉及用于治疗受试者中更年期相关病症的方法。 该方法的一个步骤可以包括将治疗递送装置插入到受试者的血管中。 接下来，治疗递送装置可以前进到与绝经相关状况相关联的交感神经系统（SNS）的目标部位基本相邻的点。 然后可以激活治疗递送装置，以将治疗信号传递给SNS的靶位点，其量足以影响受试者的交感神经活动的改变，从而治疗更年期相关的病症。
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公开(公告)号：US20190201695A1
公开(公告)日：2019-07-04
申请号：US16233611
申请日：2018-12-27
发明人： William Hsu , Ian Welsford , Mark Van Kerkwyk , Vimal Ganesan , Bruce Levin
CPC分类号： A61N1/36075 , A61N1/0546 , A61N1/36146 , A61N1/37241 , A61N1/3787
摘要： An implantable neurostimulator includes a lead comprising a plurality of electrodes at a distal end, and an implant body including electronics for controlling operation of the electrodes. An electrical connector establishes an electrical connection between the electronics and the electrodes. The implant body includes a first portion of the electrical connector, and the proximal end of the lead includes a second portion of the electrical connector. The first and second portions of the electrical connector are connectable to establish the electrical connection between the electronics and the electrodes. The lead is configured for initial implantation in the patient and the implant body is configured for subsequent implantation in the patient. The electrical connector is configured so that the connection of the first and second portions can be performed with the implant body and the lead positioned at a surgical site in the patient.
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公开(公告)号：US10137312B2
公开(公告)日：2018-11-27
申请号：US15286907
申请日：2016-10-06
摘要： In certain aspects, the present disclosure is directed to a method of improving a patient's recovery after a neuro-ischemic event. The method can include identifying a patient who has suffered a neuro-ischemic event, and stimulating, for a period of time, a parasympathetic structure in the patient's cranium before, during, and/or after the patient undergoes a task-oriented therapy to improve the patient's recovery.
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公开(公告)号：US10105091B2
公开(公告)日：2018-10-23
申请号：US14205784
申请日：2014-03-12
IPC分类号： A61B5/00 , A61B5/04 , A61B5/0484 , A61N1/08
摘要： Methods for intra-operatively monitoring nerve evoked potentials such as somatosensory nerve evoked potentials during a surgical procedure. The methods include orthodromic and antidromic monitoring of nerve evoked potentials. Monitoring includes navigating the surgical pathway to avoid insult to anatomical tissue, minimizing activation of sensory nerves that result in undesirable side effects in a patient, and determining the suitable location for placement of an implantable medical device.
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公开(公告)号：US20170281937A9
公开(公告)日：2017-10-05
申请号：US15137477
申请日：2016-04-25
发明人： Benjamin D. Pless , Shannon Schuetz
IPC分类号： A61N1/36
CPC分类号： A61N1/3606 , A61N1/36157 , A61N1/36171 , A61N1/36175
摘要： One aspect of the present disclosure relates to a method for treating a menopause-related condition in a subject. One step of the method can include inserting a therapy delivery device into a vessel of the subject. Next, the therapy delivery device can be advanced to a point substantially adjacent a target site of the sympathetic nervous system (SNS) that is associated with the menopause-related condition. The therapy delivery device can then be activated to deliver a therapy signal to the target site of the SNS in an amount and for a time sufficient to effect a change in sympathetic activity in the subject and thereby treat the menopause-related condition.
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公开(公告)号：US20170072200A1
公开(公告)日：2017-03-16
申请号：US15362124
申请日：2016-11-28
发明人： Kellie Fletcher , Patrick Hard , Anthony V. Caparso , Karen Tsuei
CPC分类号： A61N1/36075 , A61N1/0526 , A61N1/0529 , A61N1/0558 , A61N1/36071 , A61N1/36132 , A61N1/37235 , A61N1/37241 , A61N1/37247 , A61N1/37264 , A61N1/37282 , A61N1/375 , A61N1/3787
摘要： An apparatus (10) for applying stimulation therapy to a patient includes an implantable medical device (20) and a remote controller (50) for inductively powering the medical device and communicating with the medical device. The remote controller (50) includes a feedback portion (220) for helping to establish a communication link between the remote controller and the implantable medical device (20).
摘要翻译： 用于对患者施加刺激治疗的装置（10）包括可植入医疗装置（20）和用于对医疗装置进行感应供电并与医疗装置通信的遥控器（50）。 遥控器（50）包括用于帮助建立遥控器和可植入医疗装置（20）之间的通信链路的反馈部分（220）。
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39.发明申请公开(公告)号：US20170021167A1
公开(公告)日：2017-01-26
申请号：US15137477
申请日：2016-04-25
发明人： Benjamin D. Pless , Shannon Schuetz
IPC分类号： A61N1/36
CPC分类号： A61N1/3606 , A61N1/36157 , A61N1/36171 , A61N1/36175
摘要： One aspect of the present disclosure relates to a method for treating a menopause-related condition in a subject. One step of the method can include inserting a therapy delivery device into a vessel of the subject. Next, the therapy delivery device can be advanced to a point substantially adjacent a target site of the sympathetic nervous system (SNS) that is associated with the menopause-related condition. The therapy delivery device can then be activated to deliver a therapy signal to the target site of the SNS in an amount and for a time sufficient to effect a change in sympathetic activity in the subject and thereby treat the menopause-related condition.
摘要翻译： 本公开的一个方面涉及用于治疗受试者中更年期相关病症的方法。 该方法的一个步骤可以包括将治疗递送装置插入受试者的血管。 接下来，治疗递送装置可以前进到与绝经相关状况相关联的交感神经系统（SNS）的目标部位基本相邻的点。 然后可以激活治疗递送装置，以将治疗信号传递给SNS的靶位点，其量足以影响受试者的交感神经活动的改变，从而治疗更年期相关的病症。
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40.发明申请APPARATUS AND METHOD FOR DELIVERING A NEUROSTIMULATOR INTO THE PTERYGOPALATINE FOSSA 审中-公开将神经细胞输送到番茄黄素FOSSA的装置和方法公开(公告)号：US20170007283A1
公开(公告)日：2017-01-12
申请号：US15266199
申请日：2016-09-15
CPC分类号： A61B17/24 , A61B17/02 , A61B17/3211 , A61B17/3468 , A61B2017/320052 , A61N1/0526 , A61N1/0546 , A61N1/0548 , A61N1/36 , A61N1/3605 , A61N1/36057 , A61N1/375
摘要： One aspect of the present disclosure includes a neurostimulator delivery apparatus. The apparatus includes a handle portion, an elongate shaft extending from the handle portion, and a distal deployment portion. The distal deployment portion is configured to releasably mate with a neurostimulator. The neurostimulator is sized and configured for implantation into a craniofacial region of a subject.
摘要翻译： 本公开的一个方面包括神经刺激器输送装置。 该装置包括手柄部分，从把手部分延伸的细长轴和远端展开部分。 远侧展开部分构造成可释放地与神经刺激器配合。 神经刺激器的尺寸和构造用于植入受试者的颅面区域。
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