-
公开(公告)号:US20190192005A1
公开(公告)日:2019-06-27
申请号:US16222284
申请日:2018-12-17
申请人: Medlumics S.L.
摘要: A medical instrument is described that includes an optical source, an optical fiber, and a waveguide patterned upon a substrate. The optical fiber receives radiation from the optical source and includes a first segment and a second segment. The second segment is rotated about an optical axis relative to the first segment. The waveguide receives radiation from the optical source and guides a beam of radiation. The waveguide includes a first waveguide segment designed to impart a first differential group delay on the beam of radiation and a second waveguide segment designed to impart a second differential group delay on the beam of radiation. A sum of the first differential group delay and the second differential group delay is substantially zero.
-
公开(公告)号:US10206584B2
公开(公告)日:2019-02-19
申请号:US14820255
申请日:2015-08-06
申请人: Medlumics S.L.
发明人: Eduardo Margallo Balbás , Alejandro Barriga Rivera , José Luis Rubio Guivernau , Santiago Jiménez Valero , Juan Lloret Soler
IPC分类号: A61B5/00 , A61B5/02 , A61M25/09 , A61B1/00 , A61B1/07 , A61B18/18 , A61B17/00 , A61B17/22 , A61B18/00
摘要: Systems and methods for controlling a guide with the aid of optical coherence tomography (OCT) data are described. A guide wire includes at least one optical fiber, a flexible substrate, and one or more optical elements. The at least one optical fiber transmits a source beam of radiation. The flexible substrate includes a plurality of waveguides. At least one of the plurality of waveguides transmits one or more beams of radiation away from the guide wire, and at least one of the plurality of waveguides receives one or more beams of scattered radiation that have been reflected or scattered from a sample. The multiplexer generates the one or more beams of exposure radiation from the source beam of radiation. The one or more optical elements at least one of focus and steer the one or more beams of radiation.
-
公开(公告)号:US09829628B2
公开(公告)日:2017-11-28
申请号:US15448663
申请日:2017-03-03
申请人: Medlumics S.L.
CPC分类号: G02B6/122 , G02B6/136 , G02B2006/12061 , G02B2006/12097 , G02B2006/12135 , G02B2006/12142 , G02F1/025
摘要: A device and a method for manufacturing the device are presented. The device includes a ridge, a peninsula formation, and a conductive trace. The ridge is defined within a semiconducting material. The peninsula formation is also defined within the semiconducting material and is adjacent to the ridge such that a gap exists between an end face of the peninsula formation and a side wall of the ridge. The conductive trace bridges across the gap such that the conductive trace runs over a top surface of the peninsula and a top surface of the ridge.
-
公开(公告)号:US09739940B2
公开(公告)日:2017-08-22
申请号:US15065126
申请日:2016-03-09
申请人: Medlumics S.L.
CPC分类号: G02B6/122 , G02B6/12 , G02B6/12004 , G02B6/124 , G02B6/2861 , G02B6/29331 , G02B6/29332 , G02B6/29344 , G02B6/29352 , G02B2006/12104 , G02B2006/12142 , G02B2006/12147 , H01S5/1028
摘要: A photonic integrated circuit is presented that includes a substrate, and a first and second waveguide patterned on the substrate. The first waveguide guides an input beam of radiation. The photonic integrated circuit also includes a coupling region, wherein the first and second waveguides each pass through the coupling region. One or more modulating elements are coupled to each of the first and second waveguides. The first waveguide and the second waveguide have a first facet and a second facet, respectively, and first and second reflections are generated at the first and second facets within the first and second waveguides, respectively. The one or more modulating elements coupled to each of the first and second waveguides are designed to adjust the phase of the first and second reflections before the first and second reflections pass through the coupling region.
-
公开(公告)号:US09588291B2
公开(公告)日:2017-03-07
申请号:US14584592
申请日:2014-12-29
申请人: Medlumics S.L.
CPC分类号: G02B6/122 , G02B6/136 , G02B2006/12061 , G02B2006/12097 , G02B2006/12135 , G02B2006/12142 , G02F1/025
摘要: A device and a method for manufacturing the device are presented. The device includes a ridge, a peninsula formation, and a conductive trace. The ridge is defined within a semiconducting material. The peninsula formation is also defined within the semiconducting material and is adjacent to the ridge such that a gap exists between an end face of the peninsula formation and a side wall of the ridge. The conductive trace bridges across the gap such that the conductive trace runs over a top surface of the peninsula and a top surface of the ridge.
摘要翻译: 提出了一种用于制造该装置的装置和方法。 该装置包括脊,半岛形状和导电迹线。 脊部限定在半导体材料内。 半岛形成也限定在半导体材料内并且与脊相邻,使得在半岛形状的端面和脊的侧壁之间存在间隙。 导电迹线穿过间隙桥接,使得导电迹线在半岛的顶表面和脊的顶表面上延伸。
-
公开(公告)号:US20160238371A1
公开(公告)日:2016-08-18
申请号:US15014148
申请日:2016-02-03
申请人: MEDLUMICS S.L.
发明人: Juan LLORET SOLER , Juan SANCHO DURÁ , José Luis RUBIO GUIVERNAU , Eduardo MARGALLO BALBÁS , William Kennedy LANDLES , Andrés CIFUENTES , Blair UNGAR , Kirill ZINOVIEV
CPC分类号: G01B9/02051 , A61B5/0066 , A61B2562/0233 , A61B2562/228 , G01B9/02091 , G02B6/2766 , G02B6/29346 , G02B6/30 , G02B6/32 , G02B6/4221 , G02B6/4226 , G02B6/4251 , G02B6/4269 , G02B6/4271 , G02B6/4284 , G02B26/0833
摘要: A chip package includes a housing, one or more electrical connections coupled to an exterior of the housing, a photonic integrated circuit, and a scanning unit. Both the photonic integrated circuit and the scanning unit are disposed within the housing. The photonic integrated circuit has at least one waveguide designed to guide a beam of light. The scanning unit is designed to laterally scan the beam of light across a focal plane outside of the housing. The scanning unit is aligned with the photonic integrated circuit such that the beam of light is coupled between the photonic integrated circuit and the scanning unit.
摘要翻译: 芯片封装包括壳体,耦合到壳体的外部的一个或多个电连接,光子集成电路和扫描单元。 光子集成电路和扫描单元均设置在壳体内。 光子集成电路具有至少一个设计用于引导光束的波导。 扫描单元被设计成横向扫描穿过壳体外侧的焦平面的光束。 扫描单元与光子集成电路对准,使得光束耦合在光子集成电路和扫描单元之间。
-
公开(公告)号:US09261350B2
公开(公告)日:2016-02-16
申请号:US14715182
申请日:2015-05-18
申请人: Medlumics S.L.
IPC分类号: G01B9/02 , G02B6/122 , G02B6/13 , G02B6/26 , G02B6/32 , G02B6/35 , A61B5/00 , G02B6/06 , G02B6/136
CPC分类号: G01B9/02091 , A61B5/0066 , G01B9/02049 , G02B6/06 , G02B6/1221 , G02B6/13 , G02B6/136 , G02B6/262 , G02B6/32 , G02B6/3596
摘要: A system and method for depth-resolved imaging of a sample are presented. The system for depth-resolved imaging of a sample includes a substrate of substantially flexible material, a plurality of waveguides disposed on the substrate, an optical element disposed at a distal end of the plurality of waveguides, and one or more interferometers. Light is collected from the sample through the optical element and plurality of waveguides on the flexible substrate on its path to the one or more interferometers. The interferometers are configured to combine a reference light with the light received by at least a portion of the plurality of waveguides to resolve contributions from one or more depths of the sample. The system further includes a light guiding element coupled between the plurality of waveguides and the one or more interferometers.
-
公开(公告)号:US20240240931A1
公开(公告)日:2024-07-18
申请号:US18391297
申请日:2023-12-20
申请人: Medlumics S.L.
发明人: Matthieu DUPERRON , Juan SANCHO , Abel ROIGÉ , Sara MAS
IPC分类号: G01B9/02091 , A61B17/00 , A61B18/00 , A61B18/20 , A61B90/00 , G01B9/02 , G01B9/02001
CPC分类号: G01B9/02091 , A61B18/20 , G01B9/02007 , G01B9/02083 , A61B2017/00057 , A61B2018/00577 , A61B2018/00904 , A61B2090/3735
摘要: Described herein are systems and methods for optical coherence tomography with a centimetric range of scan depth and a high tolerance of a precision of lengths among different optical components. A system includes a long coherent light source, an optical interferometer with multiple optical components, an optical detector with a wide bandwidth, a data acquisition unit with high sampling rate, and a data processing unit to process information of interest.
-
39.
公开(公告)号:US20240207013A1
公开(公告)日:2024-06-27
申请号:US18392268
申请日:2023-12-21
申请人: Medlumics S.L.
发明人: Juan SANCHO DURÁ , David HERRANZ ARAGONCILLO , Christopher BAILLEUL , James L. GREENE , Matthieu DUPERRON , Abel ROIGÉ
IPC分类号: A61B90/00
CPC分类号: A61B90/37 , A61B2090/373
摘要: Described herein are systems and methods for performing optical signal analysis for tissue ablation using a catheter having viewports. A method includes transmitting illumination toward a target tissue via the viewport. The method also includes receiving, at a first viewport, a first scattered illumination from the target tissue and generating a first measurement signal based on the first scattered illumination. The method also includes receiving, at the first viewport, a second scattered illumination from the target tissue after the receiving of the first scattered illumination and generating a second measurement signal based on the second scattered illumination. The method also includes determining whether the viewport is in contact with the target tissue based on a first difference among the plurality of optical measurements meeting or crossing a first threshold value, wherein the first difference comprises a difference between the first and second measurement signals.
-
40.
公开(公告)号:US20230320592A1
公开(公告)日:2023-10-12
申请号:US18079667
申请日:2022-12-12
申请人: Medlumics S.L.
发明人: Juan SANCHO DURÁ , Sara MAS GÓMEZ , David GONZALEZ , Matthieu DUPERRON , Carlos SANZ MORENO , Jorge JIMENEZ , Alexandre ROMOSCANU , David HERRANZ ARAGONCILLO
CPC分类号: A61B5/0084 , A61B5/0066 , A61B18/02 , A61B18/1492 , A61B18/20 , A61B18/24 , A61B2090/309
摘要: Described herein are systems and methods for performing optical signal analysis and lesion predictions in ablations. A system includes a catheter coupled to a plurality of optical fibers via a connector that interfaces with a computing device. The computing device includes a memory and a processor configured to receive optical measurement data of a portion of tissue from the catheter. The processor identifies one or more optical properties of the portion of tissue by analyzing the optical measurement data and determines a time of denaturation of the portion of tissue based on the one or more optical properties. A model is created to represent a correlation between lesion depths and ablation times using the time of denaturation, the one or more optical properties, and the predetermined period of time. A predicted lesion depth for a predetermined ablation time is generated using the model.
-
-
-
-
-
-
-
-
-