Patent search ap:("Abbott Cardiovascular Systems Inc.") AND inv:"Yunbing Wang" Page 4

31.

发明申请
STENTS WITH ADHESION PROMOTING LAYER 审中-公开
Title translation: 具有粘合促进层的STENTS

公开(公告)号：US20150250625A1

公开(公告)日：2015-09-10

申请号：US14716620

申请日：2015-05-19

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Daniel Castro , Stephen D. Pacetti

IPC: A61F2/82 , A61L31/10 , A61L31/16 , A61L31/06

CPC classification number: A61F2/82 , A61F2/06 , A61F2210/0004 , A61F2210/0076 , A61F2250/0067 , A61L31/04 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/00 , A61L2420/08 , A61M29/00 , B32B17/06 , B32B27/38 , Y10T428/31511 , C08L67/04

Abstract: Stents are disclosed with an adhesion promoting layer that improves adhesion of polymer coatings over polymer surfaces of a stent substrate.

Abstract translation: 公开了支架，其具有增强聚合物涂层在支架基底的聚合物表面上的粘附性的粘附促进层。

32.

发明授权
Reducing crimping damage to a polymer scaffold 有权
Title translation: 降低聚合物支架的卷曲损伤

公开(公告)号：US09084693B2

公开(公告)日：2015-07-21

申请号：US14024572

申请日：2013-09-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Luis Vazquez , Hung T. Nguyen , Scott H. Mueller , Kathleen Yan

IPC: B29D23/00 , A61F2/958 , A61F2/95

CPC classification number: A61F2/82 , A61F2/95 , A61F2/958 , A61F2002/91566 , A61F2002/9522 , A61F2250/0067 , B29C53/30 , B29C67/0014 , B29D23/00 , B29D23/001 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , Y10T29/4994 , Y10T29/49945 , Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。通过多步骤方法将支架卷曲到导管，以在压接顺序之后增加支架导管产量。在压接顺序期间的损伤减少包括修改卷边机的叶片，采用多步压接顺序，以及在压接期间使支撑气囊膨胀以支撑支架。

33.

发明授权
Reducing crimping damage to a polymer scaffold 有权

公开(公告)号：US09044352B2

公开(公告)日：2015-06-02

申请号：US14024577

申请日：2013-09-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Luis Vazquez , Hung T. Nguyen , Scott H. Mueller , Kathleen Yan

IPC: B21D39/00 , A61F2/958 , A61F2/95 , B29D23/00

CPC classification number: A61F2/82 , A61F2/95 , A61F2/958 , A61F2002/91566 , A61F2002/9522 , A61F2250/0067 , B29C53/30 , B29C67/0014 , B29D23/00 , B29D23/001 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , Y10T29/4994 , Y10T29/49945 , Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

34.

发明申请
POLY(L-LACTIDE) STENT WITH TUNABLE DEGRADATION RATE 审中-公开
Title translation: 具有可降解速率的POLY（L-LACTIDE）STENT

公开(公告)号：US20150057744A1

公开(公告)日：2015-02-26

申请号：US14530595

申请日：2014-10-31

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Xiao Ma

IPC: A61L31/14 , A61F2/89 , A61L31/06

CPC classification number: A61L31/148 , A61F2/82 , A61F2/89 , A61F2/958 , A61F2002/30062 , A61F2210/0004 , A61K9/1647 , A61K9/204 , A61L31/06 , B29C47/0066 , B29K2067/046 , B29L2031/7534 , C08G63/08 , C08G63/90 , C08J2367/04 , C08L67/04 , C09D167/04 , C09J167/04

Abstract: Methods of making a biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal. Methods include making a poly(L-lactide) material for a stent with uniformly distributed L-lactide monomer through control of polymerization conditions during PLLA synthesis, control of post-processing conditions, or both.

Abstract translation: 公开了由聚（L-丙交酯）和低浓度的L-丙交酯单体制备可生物降解的聚合物支架的方法。调节L-丙交酯的浓度以提供适合于包括冠状动脉，外周和鼻部在内的不同治疗应用的降解行为。方法包括通过控制PLLA合成期间的聚合条件，后处理条件的控制或两者来制备具有均匀分布的L-丙交酯单体的支架的聚（L-丙交酯）材料。

35.

发明授权
Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing 有权
Title translation: 支架，包括聚（L-丙交酯）制剂，使加工过程中的分子量下降最小化

公开(公告)号：US08882825B2

公开(公告)日：2014-11-11

申请号：US14022098

申请日：2013-09-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Byron Lambert , Yunbing Wang , James Oberhauser

IPC: C08J3/28 , A61L31/00 , A61F2/82 , A61L31/06 , A61L31/14 , A61L31/04

CPC classification number: B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04

Abstract: A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.

Abstract translation: 公开了一种包括含有PLLA和聚扁桃酸酯的聚合物制剂的支架支架。聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。

36.

发明申请
BIOABSORBABLE SCAFFOLD WITH PARTICLES PROVIDING DELAYED ACCELERATION OF DEGRADATION 审中-公开
Title translation: 具有提供延迟延迟降解的颗粒的生物可溶性SCAFFOLD

公开(公告)号：US20140319724A1

公开(公告)日：2014-10-30

申请号：US14223908

申请日：2014-03-24

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , James Oberhauser

IPC: A61L31/14

CPC classification number: A61F2/82 , A61F2210/0004 , A61F2250/003 , A61L31/10 , A61L31/14 , A61L31/148 , A61L31/16

Abstract: Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed.

Abstract translation: 公开了控制可生物降解的支架支架的降解特征的方法。公开了一种生物吸收性支架，其具有并入到脚手架中的多个颗粒，其在降解过程中的诱导时间之后加速脚手架的吸收。

37.

发明申请
CONTROLLING MOISTURE IN AND PLASTICIZATION OF BIORESORBABLE POLYMER FOR MELT PROCESSING 审中-公开
Title translation: 控制用于熔融加工的可生物降解聚合物的水分和塑化

公开(公告)号：US20140298675A1

公开(公告)日：2014-10-09

申请号：US14311175

申请日：2014-06-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Bethany Steichen , Stephen Pacetti , Manish Gada , Thierry Glauser , Lothar Kleiner , Yunbing Wang , James Oberhauser , Ni Ding

IPC: B29B13/06

CPC classification number: B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/1018 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006

Abstract: Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.

Abstract translation: 公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。

38.

发明申请
METHOD TO MINIMIZE CHAIN SCISSION AND MONOMER GENERATION IN PROCESSING OF POLY(L-LACTIDE) STENT 审中-公开
Title translation: 减少聚合（L-LACTIDE）STENT处理中的链分离和单体产生的方法

公开(公告)号：US20140288628A1

公开(公告)日：2014-09-25

申请号：US14226727

申请日：2014-03-26

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , James Oberhauser

IPC: A61F2/82 , A61L31/14 , A61F2/958

CPC classification number: A61F2/82 , A61F2/958 , A61F2002/9583 , A61L31/06 , A61L31/148 , H01J2237/31 , C08L67/04

Abstract: Methods of fabricating an implantable medical devices such as stents made from biodegradable polymers are disclosed that reduce or minimize chain scission and monomer generation during processing steps. The method includes processing a poly(L-lactide) resin having an number average molecular weight between 150 to 200 kD in an extruder in a molten state. A poly(L-lactide) tube is formed from the processed resin and a stent is fabricated from the tube. The number average molecular weight of the poly(L-lactide) of the stent after sterilization is 70 to 100 kD.

Abstract translation: 公开了制造可植入医疗装置的方法，例如由可生物降解的聚合物制成的支架，其可减少或最小化加工步骤期间的链断裂和单体产生。该方法包括在熔融状态的挤出机中加工数均分子量为150〜200kD的聚（L-丙交酯）树脂。由处理后的树脂形成聚（L-丙交酯）管，并由管制造支架。灭菌后支架的聚（L-丙交酯）数均分子量为70〜100kD。

39.

发明申请
METHODS FOR CRIMPING A POLYMERIC STENT SCAFFOLD ONTO A DELIVERY BALLOON 审中-公开
Title translation: 将POLYMERIC STENT SCAFFOLD划入交付气球的方法

公开(公告)号：US20140250667A1

公开(公告)日：2014-09-11

申请号：US14280476

申请日：2014-05-16

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang

IPC: A61F2/82

CPC classification number: A61F2/82 , A61F2/915 , A61F2/958 , A61F2002/91533 , A61F2002/91566 , A61F2002/9522 , A61F2210/0071 , Y10T29/49865 , Y10T29/49885 , Y10T29/49908 , Y10T29/49909 , Y10T29/49913 , Y10T29/49915 , Y10T29/49927 , Y10T29/53657

Abstract: A medical device includes a polymer stent scaffold crimped to a catheter having an expansion balloon. A process for forming the medical device includes placing the scaffold on a support supported by an alignment carriage, and deionizing the scaffold to remove any static charge buildup on the scaffold before placing the scaffold within a crimper to reduce the scaffold's diameter. The polymer scaffold is heated to a temperature below the polymer's glass transition temperature to improve scaffold retention without adversely affecting the mechanical characteristics of the scaffold when deployed to support a body lumen.

Abstract translation: 医疗装置包括卷曲到具有膨胀气囊的导管的聚合物支架构架。用于形成医疗装置的方法包括将支架放置在由对准托架支撑的支撑件上，并且在将支架放置在卷曲器内以减少支架的直径之前，使支架去离子以去除支架上的静电荷积聚。将聚合物支架加热到低于聚合物玻璃化转变温度的温度，以改善支架保持性，而不会在展开支架体腔时对支架的机械特性产生不利影响。