Protein HDPBQ71
    33.
    发明授权
    Protein HDPBQ71 失效
    蛋白HDPBQ71

    公开(公告)号:US07091315B1

    公开(公告)日:2006-08-15

    申请号:US10103295

    申请日:2002-03-22

    摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

    摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。

    Human haemopoietic maturation factor
    40.
    发明授权
    Human haemopoietic maturation factor 失效
    人类造血成熟因子

    公开(公告)号:US06790826B2

    公开(公告)日:2004-09-14

    申请号:US10004832

    申请日:2001-12-07

    IPC分类号: A61K3816

    CPC分类号: C07K14/475 A61K38/00

    摘要: Disclosed are human haemopoietic maturation factor polypeptides and DNA (RNA) encoding such haemopoietic maturation factor polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and for using such polypeptides for treating leukemia, auto-immune diseases and blood related disorders. Antagonists against such polypeptides and their use as a therapeutic to prevent expansion of T-cell populations are also disclosed. Diagnostic assays are also disclosed to detect both the presence of mutations in the haemopoietic maturation factor nucleic acid sequences and altered levels of the protein.

    摘要翻译: 公开了人类造血成熟因子多肽和编码这种造血成熟因子多肽的DNA(RNA)。 还提供了通过重组技术产生这种多肽的方法,并且使用这些多肽来治疗白血病,自身免疫疾病和与血液相关的疾病。 还公开了抗这些多肽的拮抗剂及其作为治疗剂用于预防T细胞群扩增的用途。 还公开了诊断测定以检测造血成熟因子核酸序列中突变的存在和蛋白质的改变的水平。