Abstract:
A method and apparatus are disclosed for mounting an interferometer cavity such as a laser so that constant interferometer resonant frequency is maintained in spite of environmental vibration and other external acceleration forces. The invention can be used alone or in combination with prior art frequency stabilization system, such as shock mounts and active feedback type stabilization systems.
Abstract:
A method and apparatus are disclosed for mounting an interferometer cavity such as a laser so that constant interferometer resonant frequency is maintained in spite of environmental vibration and other external acceleration forces. The invention can be used alone or in combination with prior art frequency stabilization systems, such as shock mounts and active feedback type stabilization systems.
Abstract:
Anti-microbial wound dressings, methods of making anti-microbial wound dressings and methods of treating wounds with an anti-microbial wound dressing are provided. The anti-microbial wound dressings can include a water-soluble film-forming polymeric carrier material and a water-soluble glass-encapsulated anti-microbial agent, which is embedded within the carrier and/or coated on a surface thereof. Additional active agents useful in wound care can also be embedded in and/or coated on a surface of the carrier and/or water-soluble glass.
Abstract:
The invention relates to heterocyclic substituted carbonyl derivatives that display selective binding to dopamine D3 receptors. In another aspect, the invention relates to a method for treating central nervous system disorders associated with the dopamine D3 receptor activity in a patient in need of such treatment comprising administering to the subject a therapeutically effective amount of said compounds for alleviation of such disorder. The central nervous system disorders that may be treated with these compounds include Psychotic Disorders, Substance Dependence, Substance Abuse, Dyskinetic Disorders (e.g. Parkinson's Disease, Parkinsonism, Neuroleptic-Induced Tardive Dyskinesia, Gilles de la Tourette Syndrome and Huntington's Disease), Dementia, Anxiety Disorders, Sleep Disorders, Circadian Rhythm Disorders and Mood Disorders. The subject invention is also directed towards processes for the preparation of the compounds described herein as well as methods for making and using the compounds as imaging agents for dopamine D3 receptors.
Abstract:
The invention relates to heterocyclic substituted carbonyl derivatives that display selective binding to dopamine D3 receptors. In another aspect, the invention relates to a method for treating central nervous system disorders associated with the dopamine D3 receptor activity in a patient in need of such treatment comprising administering to the subject a therapeutically effective amount of said compounds for alleviation of such disorder. The central nervous system disorders that may be treated with these compounds include Psychotic Disorders, Substance Dependence, Substance Abuse, Dyskinetic Disorders (e.g. Parkinson's Disease, Parkinsonism, Neuroleptic-Induced Tardive Dyskinesia, Gilles de la Tourette Syndrome and Huntington's Disease), Dementia, Anxiety Disorders, Sleep Disorders, Circadian Rhythm Disorders and Mood Disorders. The subject invention is also directed towards processes for the preparation of the compounds described herein as well as methods for making and using the compounds as imaging agents for dopamine D3 receptors.
Abstract:
A system (80) for controlling deformations of optical components adapted for use with laser system aperture sharing elements (16) and deformable mirrors. The inventive system (80) includes a control loop (12, 40, 24, 20, 46, 28, 74, 78, 60, 34) for determining a desired temperature pattern. The control loop (12, 40, 24, 46, 28, 74, 78, 60, 34) provides a control signal (45) corresponding to the desired temperature pattern to a heat map applicator (18, 46, 47, 59, 60). The heat map applicator (18, 46, 47, 59, 60) applies the desired temperature pattern to the optical component (16) in response to the control signal and the optical component (16) is selectively deformed in response thereto. In a specific embodiment, the control loop (12, 40, 24, 20, 46, 28, 74, 78, 60, 34) is a closed loop control system that includes an interferometer (74). The interferometer (74) provides a first shape of the optical component (16) to a comparator circuit (20) that compares the first shape to a desired shape corresponding to the desired temperature pattern for determining the control signal. An alternative closed loop control system (12, 40, 24, 20, 46, 28, 74, 78, 60, 34) includes an infrared energy detector (12) that determines a current temperature pattern and generates the control signal in response thereto for converting the current temperature pattern to the desired temperature pattern. The heat map applicator (18, 46, 47, 59, 60) provides an electromagnetic beam (50, 52) that is swept across the optical component (16) to impart the desired temperature pattern on the optical component (16). In another illustrative embodiment, the control loop is an open loop control system that includes a complimentary electromagnetic energy beam that is swept over the optical component to form a heat pattern complimentary to the temperature pattern imparted to the optical component by a high power laser beam such that the total heat deposited on the optical component is uniform.
Abstract:
A laser rangefinding system (12) that utilizes multiple pulse, multiple return, modal range processing for clutter rejection. A laser source (16) emits a series of laser beam pulses (42), and each reflected return from objects (46) in a scene for each of the pulses is recorded. Each return signal above a predetermined threshold is added as a count to a count table within a selected bin representing the range of the return signal. After all of the analog return signals are recorded, the range bin with the most counts is selected as the range of a target.