公开(公告)号：US08185936B1

公开(公告)日：2012-05-22

申请号：US12502018

申请日：2009-07-13

申请人： Raymond Emilio Reeves ,  Ryan Alan Wick ,  Wen Xue

发明人： Raymond Emilio Reeves ,  Ryan Alan Wick ,  Wen Xue

IPC分类号： H04L29/06 ,  H04L9/00

CPC分类号： H04W12/06 ,  H04L9/0891 ,  H04L9/321 ,  H04L63/102 ,  H04L2209/80 ,  H04W8/20 ,  H04W12/08

摘要： A method and medium are provided for automatically updating user profiles based on authentication failures associated with network-access requests from mobile communications devices. A mobile communications device requests access to a mobile network and the access is rejected due to an authentication failure. Upon communicating a rejection message to the mobile communications device, the authentication server communicates a network-access rejection notification to a user-profile updating server that resets network-generated authentication credentials and provides updated profiles containing reset credentials to a provisioning server. Subsequent access requests from the mobile device are handled through a dedicated profile-provisioning home agent until the device is updated, at which time network access can be granted through a more conventional home agent.

摘要翻译： 提供了一种基于与来自移动通信设备的网络访问请求相关联的认证失败来自动更新用户简档的方法和介质。 移动通信设备请求对移动网络的访问，并且由于认证失败而拒绝访问。 在向移动通信设备传达拒绝消息时，认证服务器将网络访问拒绝通知传送到用户简档更新服务器，该用户简档更新服务器重置网络生成的认证凭证，并向配置服务器提供包含重置凭据的更新的配置文件。 来自移动设备的随后的访问请求通过专用简档配置归属代理来处理，直到设备被更新，此时可以通过更传统的归属代理授予网络访问。

公开(公告)号：US20110289410A1

公开(公告)日：2011-11-24

申请号：US12782472

申请日：2010-05-18

申请人： Lyle Walter Paczkowski ,  Farni B. Weaver ,  Talat Jamshidi ,  Nicolas A. Nehme Antoun ,  Wen Xue

发明人： Lyle Walter Paczkowski ,  Farni B. Weaver ,  Talat Jamshidi ,  Nicolas A. Nehme Antoun ,  Wen Xue

IPC分类号： G06F17/00 ,  G06F3/01 ,  H04M3/42

CPC分类号： G10L21/06 ,  G11B27/034 ,  G11B27/34

摘要： A wireless communication device comprises a wireless communication interface, a processing system, and a user interface. The wireless communication interface is configured to wirelessly receive a mixed media signal comprising a plurality of audio streams originating from different source devices. The processing system is configured to isolate the audio streams and generate graphical representations of each one of the audio streams. The user interface is configured to display the graphical representations of each one of the audio streams and receive audio stream modification instructions from a user. The processing system is configured to process the audio stream modification instructions to generate at least one modified audio stream based on the audio stream modification instructions. The user interface is configured to display a graphical representation of the modified audio stream and audibly output a modified mixed media signal comprising the modified audio stream.

摘要翻译： 无线通信设备包括无线通信接口，处理系统和用户接口。 无线通信接口被配置为无线地接收包括源自不同源设备的多个音频流的混合媒体信号。 处理系统被配置为隔离音频流并且生成每个音频流的图形表示。 用户界面被配置为显示每个音频流的图形表示，并从用户接收音频流修改指令。 处理系统被配置为处理音频流修改指令以基于音频流修改指令生成至少一个修改的音频流。 用户界面被配置为显示经修改的音频流的图形表示，并且可听地输出包括经修改的音频流的修改的混合媒体信号。

公开(公告)号：US08054754B1

公开(公告)日：2011-11-08

申请号：US12508510

申请日：2009-07-23

申请人： Wen Xue ,  Raymond E. Reeves ,  Ryan A. Wick

发明人： Wen Xue ,  Raymond E. Reeves ,  Ryan A. Wick

IPC分类号： G01R31/08

CPC分类号： H04L65/1006 ,  H04L65/1083 ,  H04L65/80 ,  H04L69/40 ,  H04M7/0084

摘要： Exemplary methods and systems may provide a soft-inactivity notification during a VoIP call, which according to an exemplary embodiment involves a SIP session and packet-data communications between participants in the VoIP call. The method comprises (a) detecting that packet-data communications in the VoIP call have been interrupted; (b) in response to determining that the packet-data communications have been interrupted, making a determination as to whether or not the SIP session is active; (c) if the SIP session is active, then initiating a soft-inactivity notification procedure; and (d) otherwise, if the SIP session is inactive, refraining from initiating the soft-inactivity notification procedure. The soft-inactivity notification thus notifies a user that while the call has been interrupted, the call may be re-established without requiring the user to reconnect.

摘要翻译： 示范性方法和系统可以在VoIP呼叫期间提供软不活动通知，其根据示例性实施例涉及VoIP会话中的参与者之间的SIP会话和分组数据通信。 该方法包括：（a）检测VoIP呼叫中的分组数据通信已被中断; （b）响应于确定分组数据通信已被中断，确定SIP会话是否活动; （c）如果SIP会话是活动的，则启动软休眠通知过程; 和（d）否则，如果SIP会话不活动，则不启动软休眠通知过程。 因此，软休息不通知通知用户在呼叫已被中断的情况下，可以重新建立呼叫，而不需要用户重新连接。

公开(公告)号：US20100273660A1

公开(公告)日：2010-10-28

申请号：US12617624

申请日：2009-11-12

申请人： Lars Zender ,  Wen Xue ,  Scott Powers ,  Scott W. Lowe

发明人： Lars Zender ,  Wen Xue ,  Scott Powers ,  Scott W. Lowe

IPC分类号： C40B20/06 ,  C07K16/00 ,  C40B50/04 ,  C40B40/06 ,  C12N5/09 ,  C12Q1/68 ,  G01N33/574

CPC分类号： A01K67/0271 ,  A01K2217/058 ,  A01K2267/0331 ,  C07K14/4747 ,  C12N15/1079 ,  C12N15/8509 ,  C12N2510/04 ,  C12N2517/02 ,  C12N2799/027 ,  C12Q1/6886 ,  C12Q2600/154 ,  C12Q2600/178 ,  G01N33/5044 ,  G01N33/5067 ,  G01N33/5088 ,  G01N33/57415 ,  G01N33/57438 ,  G01N2500/00 ,  G01N2800/50 ,  G01N2800/52

摘要： In some aspects, the invention provides a genetically tractable in situ non-human animal model for hepatocellular carcinoma. The model is useful, inter alia, in understanding the molecular mechanisms of liver cancer, in understanding the genetic alterations that lead to chemoresistance or poor prognosis, and in identifying and evaluating new therapies against hepatocellular carcinomas. The liver cancer model of this invention is made by altering hepatocytes to increase oncogene expression, to reduce tumor suppressor gene expression or both and by transplanting the resulting hepatocytes into a recipient non-human animal.The present invention also provides methods for identifying and validating tumor suppressor genes by screening pools of shRNAs that target genomic regions deleted in human cancers, such as human hepatocellular carcinomas. The present invention also provides validated tumor suppressor genes, and methods of inhibiting cell proliferation and/or tumor growth, for example by expression of such tumor suppressor genes.

摘要翻译： 在一些方面，本发明提供了用于肝细胞癌的遗传易处的非人动物模型。 该模型除其他外，有助于理解肝癌的分子机制，了解导致化学耐药性或预后不良的遗传改变，以及鉴定和评估针对肝细胞癌的新疗法。 本发明的肝癌模型通过改变肝细胞以增加癌基因表达，减少肿瘤抑制基因表达或两者并通过将所得肝细胞移植到受体非人动物中来制备。 本发明还提供了通过筛选靶向人类癌症中缺失的基因组区域（例如人肝细胞癌）的shRNA的鉴定和验证肿瘤抑制基因的方法。 本发明还提供了经过验证的肿瘤抑制基因，以及例如通过表达这种肿瘤抑制基因来抑制细胞增殖和/或肿瘤生长的方法。

公开(公告)号：US06741695B1

公开(公告)日：2004-05-25

申请号：US10115341

申请日：2002-04-03

申请人： Von McConnell ,  Wen Xue ,  Baoquan Zhang ,  Jesse Money

发明人： Von McConnell ,  Wen Xue ,  Baoquan Zhang ,  Jesse Money

IPC分类号： H04M700

CPC分类号： H04L65/104 ,  H04L12/66 ,  H04L65/1006 ,  H04L65/103 ,  H04L65/1069 ,  H04M3/4228 ,  H04M7/1225 ,  H04M2207/203

摘要： An interface engine that is communicatively connected to a packet-switched network and to a legacy circuit-switched network uses a call processing protocol, such as the session initiation protocol (SIP), for packet-switched network communications and uses a legacy signaling protocol, such as IS-41, for legacy circuit-switched communications. In response to a registration request initiated by a subscriber device on the packet-switched network, the interface engine obtains a service profile for the subscriber from a call processing system, such as a home location register (HLR), of the legacy circuit-switched network. Service parameters derived from the service profile and stored in a service database may be used to apply services on the packet-switched network for the subscriber device.

摘要翻译： 通信地连接到分组交换网络和传统电路交换网络的接口引擎使用诸如会话发起协议（SIP）的呼叫处理协议进行分组交换网络通信，并且使用传统信令协议， 例如IS-41，用于传统电路交换通信。 响应于分组交换网络上的用户设备发起的注册请求，接口引擎从诸如归属位置寄存器（HLR）的呼叫处理系统获得用于该用户的服务简档，该传统电路交换 网络。 可以使用从服务简档导出并存储在服务数据库中的服务参数来为用户设备在分组交换网络上应用服务。

公开(公告)号：US09373106B1

公开(公告)日：2016-06-21

申请号：US12767082

申请日：2010-04-26

申请人： Raymond Emilio Reeves ,  Ryan Alan Wick ,  Wen Xue ,  Thomas M. Hughson

发明人： Raymond Emilio Reeves ,  Ryan Alan Wick ,  Wen Xue ,  Thomas M. Hughson

IPC分类号： G06F21/00 ,  G06Q20/12 ,  G06F21/10 ,  G06F17/30

CPC分类号： G06Q20/123 ,  G06F17/30106 ,  G06F21/10 ,  G06F21/16 ,  G06Q20/145 ,  G06Q2220/12

摘要： Provides a consumer of digital products with an experience like that of visiting a shopping mall, where a product may be “tried on,” or downloaded, without having to pay until it's actually used. A consumer may download three identical copies of an item, but not be billed for any of the downloads until one of the copies of the item is actually installed or used on the client device. At that point, a purchase of that particular copy of the item is deemed to have occurred and the user is billed for that particular copy. The sale is credited to the provider that the particular copy is associated with, based on a transaction identifier that associates that particular copy of the item with the client device and the provider. The unused copies of the item may automatically be deleted or disabled once the purchase has occurred.

摘要翻译： 为消费者提供数字产品的消费者，具有访问购物中心的体验，即可以“尝试”或下载产品，而无需付款直到实际使用。 消费者可以下载项目的三个相同的副本，但是不会向任何下载计费，直到项目的一个副本实际上在客户端设备上安装或使用。 在这一点上，该物品的特定副本的购买被视为已经发生，并且该用户被收取该特定副本。 根据将该项目的特定副本与客户端设备和提供者相关联的事务标识符，该销售记入特定副本与之关联的提供商。 一旦购买发生，该项目的未使用的副本可能会被自动删除或禁用。

公开(公告)号：US09155125B1

公开(公告)日：2015-10-06

申请号：US12560859

申请日：2009-09-16

申请人： Wen Xue ,  Arun Santharam ,  Douglas R. Green

发明人： Wen Xue ,  Arun Santharam ,  Douglas R. Green

IPC分类号： H04W24/00 ,  H04W88/06 ,  H04W8/18

CPC分类号： H04W88/06 ,  H04L63/123 ,  H04W4/02 ,  H04W8/18 ,  H04W12/10 ,  H04W24/00

摘要： A location validation system comprising a communication interface configured to receive an asserted location of a wireless communication device and a processing system configured to determine a trusted location of the wireless communication device, receive the asserted location from the communication interface, compare the asserted location to the trusted location, and generate a notification if the asserted location differs from the trusted location.

摘要翻译： 一种位置验证系统，包括被配置为接收无线通信设备的断言位置的通信接口和被配置为确定所述无线通信设备的可信位置的处理系统，从所述通信接口接收所断言的位置，将所述断言位置与 信任的位置，并且如果断言的位置与受信任位置不同，则生成通知。

公开(公告)号：US09106507B1

公开(公告)日：2015-08-11

申请号：US13155488

申请日：2011-06-08

申请人： Talat Jamshidi ,  Jay Douglas Cole ,  Wen Xue

发明人： Talat Jamshidi ,  Jay Douglas Cole ,  Wen Xue

IPC分类号： H04L12/701 ,  H04L12/801 ,  H04L29/06

CPC分类号： H04L45/00 ,  H04L29/0653 ,  H04L69/14 ,  H04W88/06

摘要： Embodiments disclosed herein provide systems and methods for selective use of a packet voice trigger in a wireless access network. In a particular embodiment, a method provides receiving a call request for a call from a wireless device. The method further provides determining a location of the wireless device and processing an identifier for the wireless device to retrieve a device profile for the wireless device. If the device profile indicates that a trigger should be used for packet voice communications, then the method provides determining whether the trigger should be disarmed based on a quantity of the plurality of different access networks available to the wireless device at the location. If the trigger is armed, transfer the call request for delivery to the packet voice server to set up the call and, if not, process the call request in the wireless access network to set up the call.

摘要翻译： 本文公开的实施例提供了用于在无线接入网络中选择性地使用分组语音触发的系统和方法。 在特定实施例中，一种方法提供从无线设备接收对呼叫的呼叫请求。 该方法还提供确定无线设备的位置并处理无线设备的标识符以检索用于无线设备的设备简档。 如果设备配置文件指示应该使用触发器进行分组语音通信，则该方法提供确定触发器是否应该根据该位置处的无线设备可用的多个不同接入网络的数量来撤防。 如果触发器被布防，则将呼叫请求传送到分组语音服务器以建立呼叫，如果不​​是，则在无线接入网络中处理呼叫请求以建立呼叫。

公开(公告)号：US09021527B1

公开(公告)日：2015-04-28

申请号：US13033323

申请日：2011-02-23

申请人： Wen Xue ,  Jay Douglas Cole ,  Talat Jamshidi ,  Sharon Lynn Woodrum ,  Philip Martin Kunkel

发明人： Wen Xue ,  Jay Douglas Cole ,  Talat Jamshidi ,  Sharon Lynn Woodrum ,  Philip Martin Kunkel

IPC分类号： H04N5/445 ,  H04N21/41

CPC分类号： H04N21/431 ,  H04N21/4104 ,  H04N21/4126 ,  H04N21/4532 ,  H04N21/4622 ,  H04N21/478 ,  H04N21/4786 ,  H04N21/4788 ,  H04N21/4882 ,  H04N21/6118 ,  H04N21/6125 ,  H04N21/6131 ,  H04N21/6137 ,  H04N21/6168 ,  H04N21/6175 ,  H04N21/6181 ,  H04N21/6187 ,  H04N21/6587

摘要： Systems, methods, and computer-readable media for facilitating initiation of communication actions in accordance with cable attributes. In one embodiment, cable attributes are referenced that indicate utilization of a cable device at a time a communication event is directed to a user device. The user device and the cable device may be associated with the same user. Communication actions to apply in accordance with the communication event are determined based on at least one of the cable attributes. Thereafter, the communication actions are initiated, for example, such that a user is provided with an indication of the communication event visually via the cable device and/or audibly via the user device, depending on the particular cable attributes.

摘要翻译： 用于根据电缆属性促进通信动作的启动的系统，方法和计算机可读介质。 在一个实施例中，参考电缆属性，其指示电信设备在通信事件被定向到用户设备时的利用。 用户设备和电缆设备可以与相同的用户相关联。 根据通信事件应用的通信动作基于电缆属性中的至少一个来确定。 此后，通信动作被启动，例如，取决于具体的电缆属性，通过电缆设备和/或可听地通过用户设备向用户提供通信事件的指示。

公开(公告)号：US08868650B1

公开(公告)日：2014-10-21

申请号：US12834613

申请日：2010-07-12

申请人： Raymond Emilio Reeves ,  Ryan Alan Wick ,  Wen Xue

发明人： Raymond Emilio Reeves ,  Ryan Alan Wick ,  Wen Xue

IPC分类号： G06F15/16

CPC分类号： H04N7/15 ,  H04L65/1069 ,  H04L65/4038 ,  H04L67/327 ,  H04M3/567 ,  H04W4/023

摘要： Methods, devices, and products facilitate consolidating multi-user communications by redirecting calls to a multi-user device, with which multiple users can interact. A multi-user device monitors the density of users and devices within a specified distance of the multi-user device. Based at least in part on the proximity of a user, the multi-user device can designate a preferred device associated with the user and inform a multi-user-device server of the preference. The multi-user-device server provides a conference server with instructions that include contact information for the preferred devices to be used by the conference server when initiating a multi-user communication session.

摘要翻译： 方法，设备和产品有助于通过将呼叫重定向到多用户设备来合并多用户通信，多用户可以与之通信。 多用户设备监视多用户设备指定距离内的用户和设备的密度。 至少部分地基于用户的接近度，多用户设备可以指定与用户相关联的优选设备，并向多用户设备服务器通知偏好。 多用户设备服务器向会议服务器提供包括在发起多用户通信会话时要由会议服务器使用的优选设备的联系人信息的指令。