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公开(公告)号:US20250002513A1
公开(公告)日:2025-01-02
申请号:US18673168
申请日:2024-05-23
Applicant: Gilead Sciences, Inc.
Inventor: Daniel H. Byun , Gregory F. Chin , Michael O. Clarke , Bindu Goyal , Petr Jansa , Richard L. Mackman , Michael R. Mish , Dustin S. Siegel
IPC: C07F9/6561 , A61K45/06
Abstract: The present disclosure describes 4′-fluoromethyl nucleosides for treating viral infections, including Dengue.
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公开(公告)号:US12180217B2
公开(公告)日:2024-12-31
申请号:US18601528
申请日:2024-03-11
Applicant: Gilead Sciences, Inc.
Inventor: Mark J. Bartlett , Daniel H. Byun , Yifan Deng , Jennifer L. Cosman Ellis , Rao V. Kalla , Richard L Mackman , Dustin S. Siegel , Xianhuang Zeng
IPC: C07D487/04 , A61K9/00 , A61K45/06 , A61P31/14 , C07D519/00 , C07F9/6561
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US12116380B2
公开(公告)日:2024-10-15
申请号:US17820183
申请日:2022-08-16
Applicant: Gilead Sciences, Inc.
Inventor: Byoung-Kwon Chun , Michael O. Clarke , Deeba Ensan , Rao V. Kalla , Richard L Mackman , Jagadeesh N. Manda , Devan Naduthambi , Dustin S. Siegel
IPC: C07F9/09 , A61K31/706 , A61P31/14
Abstract: Phospholipid compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical formulations of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20240287109A1
公开(公告)日:2024-08-29
申请号:US18544561
申请日:2023-12-19
Applicant: Gilead Sciences, Inc.
Inventor: Daniel H. Byun , Byoung-Kwon Chun , Michael O. Clarke , Petr Jansa , Rao V. Kalla , Dmitry Koltun , Richard L. Mackman , Thao D. Perry , Dustin S. Siegel , Scott P. Simonovich
IPC: C07F9/6561 , A61K45/06
CPC classification number: C07F9/6561 , A61K45/06
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20240279186A1
公开(公告)日:2024-08-22
申请号:US18428316
申请日:2024-01-31
Applicant: Gilead Sciences, Inc.
Inventor: Mark J. Bartlett , Gregory F. Chin , Michael O. Clarke , Jennifer L. Cosman , Deeba Ensan , Bindu Goyal , Stephen Ho , Richard L. Mackman , Michael R. Mish , Dustin S. Siegel , Kyle C. Tamshen , Hai Yang
IPC: C07D247/00
CPC classification number: C07D247/00
Abstract: Provided herein is A compound of Formula I:
or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.-
公开(公告)号:US20240174704A1
公开(公告)日:2024-05-30
申请号:US18354362
申请日:2023-07-18
Applicant: GILEAD SCIENCES, INC.
Inventor: Gregory F. Chin , Byoung-Kwon Chun , Michael O. Clarke , Bindu Goyal , Hon C. Hui , Petr Jansa , Richard L. Mackman , Dustin S. Siegel , Hai Yang
IPC: C07F9/6561 , A61P31/14
CPC classification number: C07F9/6561 , A61P31/14
Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
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公开(公告)号:US20240150359A1
公开(公告)日:2024-05-09
申请号:US18237152
申请日:2023-08-23
Applicant: Gilead Sciences, Inc.
Inventor: Mark J. Bartlett , Daniel H. Byun , Yifan Deng , Jennifer L. Cosman Ellis , Rao V. Kalla , Richard L. Mackman , Dustin S. Siegel , Xianhuang Zeng
IPC: C07D487/04 , A61K9/00 , A61K45/06 , A61P31/14 , C07D519/00 , C07F9/6561
CPC classification number: C07D487/04 , A61K9/0053 , A61K45/06 , A61P31/14 , C07D519/00 , C07F9/6561
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US11919869B2
公开(公告)日:2024-03-05
申请号:US18050404
申请日:2022-10-27
Applicant: Gilead Sciences, Inc.
Inventor: Mark J. Bartlett , Gregory F. Chin , Michael O. Clarke , Jennifer L Cosman , Deeba Ensan , Bindu Goyal , Stephen Ho , Richard L Mackman , Michael R. Mish , Dustin S. Siegel , Kyle C. Tamshen , Hai Yang
IPC: C07D247/00
CPC classification number: C07D247/00
Abstract: Provided herein is A compound of Formula I:
or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.-
公开(公告)号:US11845755B2
公开(公告)日:2023-12-19
申请号:US18117913
申请日:2023-03-06
Applicant: Gilead Sciences, Inc.
Inventor: Mark J. Bartlett , Daniel H. Byun , Yifan Deng , Jennifer L. Cosman Ellis , Rao V. Kalla , Richard L. Mackman , Dustin S. Siegel , Xianhuang Zeng
IPC: A61K31/53 , A61P31/14 , C07D487/04 , A61K45/06 , A61K9/00
CPC classification number: C07D487/04 , A61K9/0053 , A61K45/06 , A61P31/14
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号:US20230279015A1
公开(公告)日:2023-09-07
申请号:US18117913
申请日:2023-03-06
Applicant: Gilead Sciences, Inc.
Inventor: Mark J. Bartlett , Daniel H. Byun , Yifan Deng , Jennifer L. Cosman Ellis , Rao V. Kalla , Richard L. Mackman , Dustin S. Siegel , Xianhuang Zeng
IPC: C07D487/04 , A61K9/00 , A61P31/14 , A61K45/06
CPC classification number: C07D487/04 , A61K9/0053 , A61P31/14 , A61K45/06
Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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