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公开(公告)号：US20090110711A1
公开(公告)日：2009-04-30
申请号：US11933017
申请日：2007-10-31
CPC分类号： A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
摘要： The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
摘要翻译： 本发明提供具有包含缓慢溶解性聚合物或材料的涂层的可植入装置及其制造和使用方法。
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公开(公告)号：US20080287911A1
公开(公告)日：2008-11-20
申请号：US11749665
申请日：2007-05-16
IPC分类号： A61M25/01
CPC分类号： A61M25/0082 , A61M25/01 , A61M2025/0004 , A61M2025/0073 , A61M2206/11
摘要： Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed.
摘要翻译： 公开了具有层流生物活性剂递送性质的导管和用于治疗或预防血管疾病的方法。
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公开(公告)号：US20080147164A1
公开(公告)日：2008-06-19
申请号：US11639079
申请日：2006-12-13
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/91 , A61F2002/9522 , A61L31/06 , Y10T29/49771 , Y10T29/49908 , Y10T29/49913 , Y10T29/49938 , C08L67/04
摘要： Disclosed herein is a method of fabricating a stent assembly comprising radially expanding a polymeric tube to an optimal degree of radial expansion; fabricating a stent from the expanded polymeric tube; and crimping the stent onto a catheter assembly, wherein the temperature of the stent during crimping is an optimal crimping temperature, wherein the optimal degree of radial expansion and the optimal crimping temperature correspond to an optimal fracture toughness exhibited by the crimped stent upon its deployment as a function of degree of radial expansion and crimping temperature.
摘要翻译： 本文公开了一种制造支架组件的方法，包括将聚合物管径向膨胀至最佳径向膨胀程度; 从扩张的聚合物管制造支架; 并将支架卷曲到导管组件上，其中在卷曲期间支架的温度是最佳卷曲温度，其中最佳径向膨胀程度和最佳卷曲温度对应于卷曲支架在展开时表现出的最佳断裂韧性 径向膨胀度和卷曲温度的函数。
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公开(公告)号：US20070292495A1
公开(公告)日：2007-12-20
申请号：US11454813
申请日：2006-06-15
CPC分类号： A61K9/5115 , A61K9/0009 , A61K9/127 , A61K41/0019 , A61K41/0028
摘要： Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
摘要翻译： 提供包含纳米壳的纳米构建体和使用纳米构建体治疗或改善医学状况的方法。
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35.发明申请公开(公告)号：US20120276185A1
公开(公告)日：2012-11-01
申请号：US13544749
申请日：2012-07-09
IPC分类号： A61F2/00 , A61K47/00 , A61K47/42 , A61K47/36 , A61K47/38 , A61F2/82 , C08B37/08 , C08B1/00 , C07H1/00 , C08G63/08 , C08F16/06 , A61K9/00 , A61K47/30 , C07K14/78
CPC分类号： A61L31/148 , A61F2/82 , A61L27/34 , A61L27/58 , A61L29/085 , A61L29/148 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/602 , C08L1/286 , C08L5/08 , C08L89/00 , C09D101/286 , C09D105/08 , C09D189/00
摘要： The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.
摘要翻译： 本发明提供了具有包含聚电解质和抗衡离子的生物可溶性涂层的可植入装置及其制备和使用方法。
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公开(公告)号：US20120185034A1
公开(公告)日：2012-07-19
申请号：US13427608
申请日：2012-03-22
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/82
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can serve as a primer coating for subsequent coatings that can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译： 提供用于可植入装置或腔内假体（例如支架）的涂层，包括形成涂层的方法。 涂层可以用作后续涂层的底漆涂层，其可用于递送活性成分或活性成分的组合。
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37.发明申请Polymer-Bioceramic Composite Implantable Medical Device with Different Types of Bioceramic Particles 审中-公开聚合物 - 生物陶瓷复合植入式医疗器械与不同类型的生物陶瓷颗粒公开(公告)号：US20110202126A1
公开(公告)日：2011-08-18
申请号：US13096655
申请日：2011-04-28
申请人： Yunbing Wang , David C. Gale , Syed F.A. Hossainy
发明人： Yunbing Wang , David C. Gale , Syed F.A. Hossainy
IPC分类号： A61F2/82
摘要： Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed.
摘要翻译： 公开了由具有不同类型的生物陶瓷颗粒的聚合物/生物陶瓷复合材料制成的植入式医疗装置。
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公开(公告)号：US20100323093A1
公开(公告)日：2010-12-23
申请号：US12766758
申请日：2010-04-23
IPC分类号： B05D3/02
CPC分类号： B29C65/76 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61F2310/00389 , A61L31/14 , A61L31/148 , A61L2420/02 , B05D1/38 , B05D3/0254 , B05D3/0473 , B29C65/10 , B29K2067/046 , B29K2105/258 , B29L2031/7534
摘要： Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
摘要翻译： 本文描述了用于涂覆支架的方法的各种实施例。 公开了将包含聚合物组分和溶剂的组合物施用到支架基底，然后将聚合物组分暴露于等于或大于聚合物组分的Tg的温度。 重复施加和暴露一次或多次以形成涂层，结果是在最终曝光步骤之后涂层的溶剂含量处于适合成品支架的水平。
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公开(公告)号：US20100198341A1
公开(公告)日：2010-08-05
申请号：US12723561
申请日：2010-03-12
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/06
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
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公开(公告)号：US20100198340A1
公开(公告)日：2010-08-05
申请号：US12723556
申请日：2010-03-12
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/06
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译： 提供用于可植入装置或腔内假体（例如支架）的涂层，包括形成涂层的方法。 涂层可用于递送活性成分或活性成分的组合。
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