摘要:
A method for forming isolation structure for MOS transistor is disclosed, which includes forming a first photoresist layer over a sacrificed oxide layer of a semiconductor substrate, patterning the first photoresist layer to define a PMOS active region and a PMOS isolation region; implanting nitrogen ions into the PMOS isolation region through the sacrificed oxide layer by using the first photoresist layer as a mask; removing the first photoresist layer; forming a second photoresist layer over the sacrificed oxide layer, patterning the second photoresist layer to define a NMOS active region and a NMOS isolation region; implanting oxygen ions into the NMOS isolation region through the sacrificed oxide layer by using the second photoresist layer as a mask; removing the second photoresist layer and the sacrificed oxide layer; and annealing the semiconductor substrate to form isolation structures of PMOS and NMOS, respectively.
摘要:
A method and system of managing user access in a computing system is provided. The system can include an operations controller in communication with the computing system for managing the commercial transactions of the computing system over the internet, and an access management controller in communication with the operations controller. The access management controller can receive an input comprising user roles and actions associated with the computing system. The access management controller can generate a matrix indicating a relationship between the user roles and the actions. The access management controller can provide the input to the operations controller for implementation of access rules in accordance with the relationship indicated in the matrix. The access management controller can attempt to access in the computing system at least a portion of the user roles and actions after the operations controller has implemented the access rules. The access management controller can compares the attempted access with the relationship indicated in the matrix to determine access discrepancies.
摘要:
Provided is a process for producing imatinib and salts thereof, e.g., imatinib mesylate. The process includes reacting4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid with N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine in the presence of a carboxylic acid coupling reagent, to produce imatinib, and optionally converting the imatinib into a salt.
摘要:
A process for preparing carbostyril derivatives such as aripiprazole is described. Dichlorophenylpiperazine or an acid addition salt thereof is reacted with a compound of formula X—C4H8—Y or X—C4H6—Y to produce a novel quaternary spiro ammonium salt intermediate which is optionally isolated and purified. The quaternary spiro ammonium salt intermediate is reacted with 7-hydroxydihydrocarboxystyryl to produce the carbostyril derivative.
摘要翻译:描述了制备喹诺酮类衍生物如阿立哌唑的方法。 二氯苯基哌嗪或其酸加成盐与式XC 4 H 8 -Y或XC 4 H 6的化合物反应, 以制备可选地分离和纯化的新型四元螺铵盐中间体。 四环螺铵盐中间体与7-羟基二氢甲酰苯乙烯基反应生成喹诺酮衍生物。
摘要:
The present disclosure provides chips, devices and methods for sequencing a biomolecule. The biomolecule may be DNA, RNA. a protein, or a peptide. The chip comprises a substrate; a first and second fluid chamber; fluid channels connecting the first and second fluid chamber; a first and second electrode disposed on opposing sides of the central fluid channel and having a nanogap therebetween, wherein the width of the nanogap is modulated by confined electrochemical deposition; and a passivation layer disposed on top of the first and second electrodes and the fluid channel.
摘要:
This disclosure provides systems, methods, and apparatus related to optical microscopy. In one aspect, an apparatus includes a sample holder, a first objective lens, a plurality of optical components, a second objective lens, and a mirror. The apparatus may directly image a cross-section of a sample oblique to or parallel to the optical axis of the first objective lens, without scanning.
摘要:
The process for preparing 2-hydroxyphenyl alkenyl benzotriazole compounds and the process for preparing siloxane compounds containing 2-hydroxyphenyl benzotriazole function are disclosed.
摘要:
This disclosure provides systems, methods, and apparatus related to nanophotonics. In one aspect, an arrangement of waveguides includes a substrate and three waveguides. Each of the three waveguides may be a linear waveguide. A second waveguide is positioned between a first waveguide and a third waveguide. The dimensions and positions of the first, the second, and the third waveguides are specified to substantially eliminate coupling between the first waveguide and the third waveguide over a distance of about 1 millimeter to 2 millimeters along lengths of the first waveguide, the second waveguide, and the third waveguide.
摘要:
An electrochemical test sensor for detecting the concentration of an analyte in a fluid sample. The electrochemical test sensor includes a housing that has a first end and a second opposing end. The housing includes an opening at the first end to receive a fluid test sample. An electrode assembly includes a substrate, a working electrode, a counter electrode and a reagent. The substrate has a first surface and an opposing second surface. The working electrode is disposed on the first surface of the substrate, and the counter electrode is disposed on the second surface of the substrate. The electrode assembly is positioned within the housing to define a reaction channel. The electrochemical test sensor may be used with a removable lancet mechanism or integrated within a lancet mechanism to form one integral unit.