公开(公告)号：US06675107B2

公开(公告)日：2004-01-06

申请号：US10319692

申请日：2002-12-16

申请人： Masahito Ito ,  Kisaburo Deguchi ,  Yoshiaki Seki

发明人： Masahito Ito ,  Kisaburo Deguchi ,  Yoshiaki Seki

IPC分类号： G06F1900

CPC分类号： G06F17/10 ,  G01N30/8641

摘要： A method of properly correcting a base line. A concept of flexibility of a base line is introduced as an input index and a gravitation is presumed between the base line and signal data which is measured, thereby constructing a method of correcting the base line which changes gentler than a change in signal with respect to time in a peak area and which is sensitive to an area where a value of the signal data is small. A base line like a natural and smooth curve which isn't easily influenced by a local change in signal such as noise or the like can be set by an input of the flexibility.

摘要翻译： 一种正确校正基线的方法。 引入基线的灵活性的概念作为输入索引，并且在基线和被测量的信号数据之间推测引力，由此构建校正基线相对于相对于信号的信号变化更为温和的方法 在峰值区域中的时间，并且其对信号数据的值较小的区域敏感。 可以通过输入灵活性来设定像自然平滑曲线的基线，其不容易受诸如噪声等信号的局部变化的影响。

公开(公告)号：US6076047A

公开(公告)日：2000-06-13

申请号：US250279

申请日：1999-02-16

申请人： Masahito Ito ,  Kisaburo Deguchi ,  Yoshiaki Seki

发明人： Masahito Ito ,  Kisaburo Deguchi ,  Yoshiaki Seki

IPC分类号： G01N30/86 ,  G06F17/10 ,  G06F19/00

CPC分类号： G06F17/10 ,  G01N30/8641

摘要： A method of properly correcting a base line. A concept of flexibility of a base line is introduced as an input index and a gravitation is presumed between the base line and signal data which is measured, thereby constructing a method of correcting the base line which changes gentler than a change in signal with respect to time in a peak area and which is sensitive to an area where a value of the signal data is small. A base line like a natural and smooth curve which isn't easily influenced by a local change in signal such as noise or the like can be set by an input of the flexibility.

公开(公告)号：US5839496A

公开(公告)日：1998-11-24

申请号：US746386

申请日：1996-11-08

申请人： Satoru Kito ,  Masahito Ito ,  Fuminori Matuda ,  Eiki Takeshima ,  Yasuji Tanaka ,  Takahiro Fujii ,  Kenjiro Izutani

发明人： Satoru Kito ,  Masahito Ito ,  Fuminori Matuda ,  Eiki Takeshima ,  Yasuji Tanaka ,  Takahiro Fujii ,  Kenjiro Izutani

IPC分类号： B22F1/02 ,  C22C13/02 ,  C25D3/60 ,  C25D7/00 ,  B22D19/14

CPC分类号： B22F1/02 ,  B22F1/025 ,  C22C13/02 ,  C25D7/00 ,  C25D3/60 ,  Y10T428/12181 ,  Y10T428/12486 ,  Y10T428/12722 ,  Y10T428/12944 ,  Y10T428/12951 ,  Y10T428/256 ,  Y10T428/2991

摘要： Disclosed are a composite material having an anti-wear property and a process for producing the same. The composite material includes a matrix of a low melting point Sn alloy having a melting point of from 80.degree. to 280.degree. C., and metallic dispersing particles dispersed in the matrix in an amount of from 10 to 50% by volume. When the composite material is utilized to make a rough mold for preparing a prototype, it sharply improves the anti-wear property of the rough mold, and it can be refused for a plurality of times without adversely affecting the sharply improved anti-wear property. The composite material provides the advantageous effect best when the metallic dispersing particles are Fe-C alloy dispersing particles and/or Fe-W-C alloy dispersing particles which were subjected to a surface treatment including an Sn or Ni electroplating followed by a ZnCl.sub.2 .multidot.NH.sub.4 Cl flux depositing.

摘要翻译： 公开了具有抗磨损性的复合材料及其制造方法。 该复合材料包括熔点为80-280℃的低熔点Sn合金基体和分散在基质中的金属分散颗粒，其量为10至50体积％。 当将复合材料用于制备用于制备原型的粗模时，其大大提高了粗模的抗磨损性能，并且可以多次拒绝，而不会不利地影响急剧改善的抗磨损性能。 当金属分散颗粒是Fe-C合金分散颗粒和/或Fe-W-C合金分散颗粒时，复合材料最好地提供了有利效果，该颗粒经受了包括Sn或Ni电镀，然后是ZnCl 2 x NH 4 Cl熔剂沉积的表面处理。

公开(公告)号：US5804142A

公开(公告)日：1998-09-08

申请号：US756430

申请日：1996-11-26

申请人： Masahito Ito ,  Junkichi Miura ,  Yoshio Fujii ,  Hiroshi Satake ,  Kasumi Yoshida

发明人： Masahito Ito ,  Junkichi Miura ,  Yoshio Fujii ,  Hiroshi Satake ,  Kasumi Yoshida

IPC分类号： G01N30/86 ,  G01N30/62 ,  G01N30/88 ,  G01N30/02

CPC分类号： G01N30/88 ,  G01N2030/626 ,  G01N2030/8804

摘要： A reference sample having a known concentration is injected into a chromatograph system before an unknown sample is analyzed. This is for the purpose of checking the deterioration of system performance or in other words for the purpose of checking system suitability. In the present invention, the chromatographic characteristic of the check sample at the time of deterioration of the system suitability is expected and stored in a memory in advance to be related to factors of deterioration of system suitability. A factor of deterioration is deduced by comparison between the actually analyzed chromatographic characteristic of the check sample and the relational data stored in the memory. A guidance required for removing the factor is displayed. Disclosed are preferred embodiments of a chromatograph system suitable for analyzing catecholamine or glycated hemoglobin.

摘要翻译： 在分析未知样品之前，将具有已知浓度的参考样品注入色谱系统中。 这是为了检查系统性能的恶化，换句话说是为了检查系统适用性。 在本发明中，期望在系统适用性恶化时检查样品的色谱特性，并预先存储在存储器中，以与系统适用性的劣化因素相关。 通过比较检查样品的实际分析色谱特征和存储在存储器中的关系数据，推导出劣化因素。 显示删除因子所需的指导。 公开了适用于分析儿茶酚胺或糖化血红蛋白的色谱系统的优选实施方案。

公开(公告)号：US5641454A

公开(公告)日：1997-06-24

申请号：US258635

申请日：1994-06-10

申请人： Satoru Kito ,  Masahito Ito ,  Fuminori Matuda ,  Eiki Takeshima ,  Yasuji Tanaka ,  Takahiro Fujii ,  Kenjiro Izutani

发明人： Satoru Kito ,  Masahito Ito ,  Fuminori Matuda ,  Eiki Takeshima ,  Yasuji Tanaka ,  Takahiro Fujii ,  Kenjiro Izutani

IPC分类号： B22F1/02 ,  C22C13/02 ,  C25D3/60 ,  C25D7/00

CPC分类号： B22F1/02 ,  B22F1/025 ,  C22C13/02 ,  C25D7/00 ,  C25D3/60 ,  Y10T428/12181 ,  Y10T428/12486 ,  Y10T428/12722 ,  Y10T428/12944 ,  Y10T428/12951 ,  Y10T428/256 ,  Y10T428/2991

摘要： Disclosed are a composite material having an anti-wear property and a process for producing the same. The composite material includes a matrix of a low melting point Sn alloy having a melting point of from 80.degree. to 280.degree. C., and metallic dispersing particles dispersed in the matrix in an amount of from 10 to 50% by volume. When the composite material is utilized to make a rough mold for preparing a prototype, it sharply improves the anti-wear property of the rough mold, and it can be re-used for a plurality of times without adversely affecting the sharply improved anti-wear property. The composite material provides the advantageous effect best when the metallic dispersing particles are Fe--C alloy dispersing particles and/or Fe--W--C alloy dispersing particles which were subjected to a surface treatment including an Sn or Ni electroplating followed by a ZnCl.sub.2.NH.sub.4 Cl flux depositing.

摘要翻译： 公开了具有抗磨损性的复合材料及其制造方法。 该复合材料包括熔点为80-280℃的低熔点Sn合金基体和分散在基质中的金属分散颗粒，其量为10至50体积％。 当复合材料用于制备原型的粗模时，它大大提高了粗模的抗磨损性能，可以重复使用多次，而不会对抗磨损性能有显着改善 属性。 当金属分散颗粒是Fe-C合金分散颗粒和/或Fe-WC合金分散颗粒时，复合材料最有效地进行了表面处理，其包括Sn或Ni电镀，随后是ZnCl 2·NH 4 Cl助熔剂沉积 。

公开(公告)号：US08496819B2

公开(公告)日：2013-07-30

申请号：US12146912

申请日：2008-06-26

申请人： Katsutoshi Shimizu ,  Masahito Ito ,  Kimihiko Ishii ,  Yoshihiro Nagaoka ,  Kisaburo Deguchi ,  Takefumi Yokokura

发明人： Katsutoshi Shimizu ,  Masahito Ito ,  Kimihiko Ishii ,  Yoshihiro Nagaoka ,  Kisaburo Deguchi ,  Takefumi Yokokura

IPC分类号： B01D15/08 ,  G01N30/02 ,  C02F1/28

CPC分类号： B01D15/22 ,  B01J20/282 ,  B01J2220/82 ,  B01J2220/825 ,  G01N30/22 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/6069 ,  G01N2030/522 ,  G01N2030/528

摘要： Both a column having high-pressure resistance and capable of performing high-speed separation and analysis even with a small flow rate and a liquid chromatograph apparatus using the column are provided. A separation column according to the present invention has a monolithic rod being arranged in the center, being made of a porous material, and having a circular cross section, a filler layer arranged such that it encircles a circumferential surface of the monolithic rod, and a cylindrical support medium arranged outside the filler layer. The filler layer is formed by filling a tube-like gap between the monolithic rod and the support medium with particles or beads.

摘要翻译： 提供了具有高耐压性并且即使以小流量进行高速分离和分析的柱和使用该柱的液相色谱装置。 根据本发明的分离柱具有中心的整体式杆，由多孔材料制成，并且具有圆形横截面，填充层布置成使其围绕整体式杆的圆周表面，并且 圆柱形支撑介质布置在填充层外部。 通过在颗粒或珠粒之间填充整体棒和支撑介质之间的管状间隙来形成填充层。

公开(公告)号：US08375772B2

公开(公告)日：2013-02-19

申请号：US12244846

申请日：2008-10-03

申请人： Masato Fukuda ,  Hiroyuki Wada ,  Masahito Ito ,  Hironori Kaji ,  Kosaku Toyosaki

发明人： Masato Fukuda ,  Hiroyuki Wada ,  Masahito Ito ,  Hironori Kaji ,  Kosaku Toyosaki

IPC分类号： G01N30/04

CPC分类号： G01N30/34

摘要： An object of the present invention is to improve the accuracy in analysis repeatability of a liquid chromatography apparatus that feeds different eluent by use of a plurality of pumps and achieves the mixture of eluent.Each of the pumps includes means for notifying an automatic sampler and a higher-level control unit that the specified timing of a liquid feeding cycle is reached. A pump whose liquid feeding cycle is the slowest transmits own information so that analysis is synchronized with a liquid feeding cycle. Moreover, a cycle position of a liquid feeding cycle at the end of analysis is expected, and the analysis time is automatically adjusted so that the wait time until the start of the next analysis becomes the shortest.

摘要翻译： 本发明的目的是提高通过使用多个泵进料不同洗脱液的液相色谱仪的分析重复性的准确性，并实现洗脱液的混合。 每个泵包括用于通知自动取样器和上位控制单元的装置，以达到给定循环的指定时间。 送液周期最慢的泵传送自己的信息，使分析与液体供给循环同步。 此外，期望在分析结束时的送液循环的循环位置，并且自动调整分析时间，使得直到下一次分析开始的等待时间变得最短。

公开(公告)号：US20110303599A1

公开(公告)日：2011-12-15

申请号：US13202722

申请日：2010-03-10

申请人： Norimasa Minamoto ,  Masahito Ito ,  Kisaburo Deguchi ,  Hiroyuki Tanai ,  Kiyotoshi Mori

发明人： Norimasa Minamoto ,  Masahito Ito ,  Kisaburo Deguchi ,  Hiroyuki Tanai ,  Kiyotoshi Mori

IPC分类号： B01D15/08 ,  B01D39/10

CPC分类号： G01N30/603

摘要： In a liquid chromatograph, the disulfide adsorption of iron atoms in a filter for a column is avoided and thus peak tailing in a chromatogram is prevented to thereby prevent a lowering in the sample recovery rate. A liquid chromatograph column comprising a hollow tubular column body, a bead-shaped packing material which is packed in the hollow part of the column body, a filter provided with a mesh which has a mesh size smaller than the particle diameter of the packing material, and a cap which presses the filter against the packing material to thereby enclose the packing material within the column body, characterized in that the main component of the filter is nickel or hastelloy.

摘要翻译： 在液相色谱仪中，避免了用于柱的过滤器中的铁原子的二硫键吸附，因此防止了色谱图中的峰值拖尾，从而防止了样品回收率的降低。 一种液相色谱柱，包括中空管状柱体，填充在柱体中空部分中的珠状包装材料，具有筛网尺寸小于包装材料粒径的筛网的过滤器， 以及将过滤器压靠在包装材料上的盖子，从而将包装材料包围在柱体内，其特征在于，过滤器的主要部件是镍或哈氏合金。

公开(公告)号：US08008484B2

公开(公告)日：2011-08-30

申请号：US11632832

申请日：2005-07-21

申请人： Koichi Araki ,  Sachio Kudo ,  Yoshitaka Sato ,  Masahito Ito ,  Takuya Gomibuchi ,  Yasuo Araki ,  Tetsuya Inuta ,  Keiji Endo ,  Shinichi Shirakura ,  Shin Nakamura

发明人： Koichi Araki ,  Sachio Kudo ,  Yoshitaka Sato ,  Masahito Ito ,  Takuya Gomibuchi ,  Yasuo Araki ,  Tetsuya Inuta ,  Keiji Endo ,  Shinichi Shirakura ,  Shin Nakamura

IPC分类号： C07D251/20 ,  C07D251/24

CPC分类号： A01N43/54 ,  A01N43/66 ,  C07D239/24 ,  C07D239/52 ,  C07D251/12 ,  C07D251/20

摘要： Compounds of the formula (I), wherein Z represents C—R7 or N, and R5 represents alkyl that may be optionally substituted, alkenyl, alkynyl, cycloalkyl or alkoxycarbonylamino, are useful as agricultural and horticultural fungicides.

摘要翻译： 式（I）化合物，其中Z代表C-R7或N，R5代表任选取代的烷基，烯基，炔基，环烷基或烷氧基羰基氨基，可用作农业和园艺杀真菌剂。

公开(公告)号：US20090288473A1

公开(公告)日：2009-11-26

申请号：US12470164

申请日：2009-05-21

申请人： Takaaki Suzuki ,  Masato Fukuda ,  Masahito Ito

发明人： Takaaki Suzuki ,  Masato Fukuda ,  Masahito Ito

IPC分类号： G01N30/16

CPC分类号： G01N30/8665 ,  G01N30/16 ,  G01N30/28 ,  G01N30/52 ,  G01N30/8658 ,  G01N30/8693 ,  G01N2030/027

摘要： When transfer a method from a measurement system of a liquid chromatograph to a measurement system under a condition of a high pressure and a high velocity, an influence due to analysis condition cannot be neglected. Further, since a transfer value obtained by calculation is a logical value, an improper result can be obtained in an actual measurement. Further, since conventional methods are optimized by such as know-how based on previous experiences, how to carry on these know-how to a new method is remained to be solved.One of the features of the present invention is to use a value of dwell volume so as to minimize a deviation of measurement result due to methods before and after transfer. Another is, when a deviation of the measurement result is caused, to calculate a correction value for correcting the deviation from analysis of measurement data and to automatically reflect the correction value for the method transfer.

摘要翻译： 当在高压和高速条件下将方法从液相色谱仪的测量系统转移到测量系统时，不能忽视由分析条件引起的影响。 此外，由于通过计算获得的转印值是逻辑值，因此在实际测量中可以获得不正确的结果。 此外，由于常规方法通过诸如以往经验的专有技术进行优化，所以仍然需要解决如何进行这些专门知识的新方法。 本发明的特征之一是使用驻留体积的值，以便最小化由于转移之前和之后的方法导致的测量结果的偏差。 另一个原因是当测量结果偏离时，计算用于校正偏离分析测量数据的偏差的校正值，并自动反映方法传送的校正值。