Abstract:
A laser projection system includes a light source, an optical scanning component, a focusing component, a speckle reduction diffusing surface, and an optical collimating component. The light source may include at least one laser configured to emit an output beam. The focusing component focuses the output beam at a first focused point. The speckle reduction diffusing surface is selectively introduced into an optical path at the first focused point. The optical collimating component collimates the output beam onto the optical scanning component. At least a portion of a scanned laser image is generated on a projection surface by operating the laser for optical emission of encoded image data and controlling the optical scanning component to scan the output beam. The optical collimating component images the first focused point at a second focused point at the projection surface when the speckle reduction diffusing surface is in the optical path.
Abstract:
An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects.
Abstract:
Optical reader systems and methods for label-independent reading of resonant waveguide (RWG) biosensors operably supported by a microplate as defined herein. The system includes a light source, a spectrometer unit, a beam-forming optical system and a scanning optical system that includes a scanning mirror device, a mirror device driver operably coupled to the scanning mirror device, and an F-theta lens arranged between the microplate and the beam-forming optical system. Some systems use multiple optical beams to scan multiple biosensors at once without having to move the microplate. Asynchronous scanning of multiple beams allows for reducing the number of spectrometer units needed.
Abstract:
A method of measuring a resonant wavelength of a resonant waveguide (RWG) biosensor in an array of RWG biosensors supported by a microplate in a label-independent optical reader is disclosed. An exemplary method includes scanning a light spot over the RWG biosensor to obtain a plurality of spectra from both a central portion and at least one edge portion of the RWG biosensor. The method includes calculating a weighted-average spectrum for the biosensor by averaging the plurality of spectra while applying greater weight to the central portion than to the at least one edge portion. The method includes determining the resonant wavelength from the weighted-average spectrum. The resulting resonant wavelength measurement has substantially reduced noise and provides improved performance for label-independent scanning optical reader systems that use scanned optical beams.
Abstract:
An optical reader system and method are described herein that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after being removed from and then reinserted into the optical reader system. In one embodiment, the biosensors are incorporated within the wells of a microplate.
Abstract:
An optical reader system and method are described herein that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after being removed from and then reinserted into the optical reader system. In one embodiment, the biosensors are incorporated within the wells of a microplate.
Abstract:
Glass inspection systems are provided for detecting particles and defects in or on a glass sheet or glass ribbon (2, 14). The system is mounted so that the surface (1) to be inspected is in the object plane of a reflective lens (10). The lens images a thin stripe area, long in the direction tangent to the lens circumference and short in the radial direction, onto a linescan camera (18). A line illuminator (12) can be mounted so that it illuminates the stripe area. To perform the inspection, the system is moved with respect to the glass in the direction perpendicular to the long axis of the stripe, either by moving the system over the glass or by moving the glass while the system is fixed. Image information is collected by the linescan camera during this motion and assembled into an image.
Abstract:
A method of controlling a frequency-converted laser source is provided where the laser source comprises a laser cavity, an external optical feedback component, a wavelength selective component, and a wavelength conversion device and the method comprises driving a gain section of the laser cavity with a gain signal that comprises a data component and a modulation component. The modulation component of the gain signal comprises a gain modulation amplitude IMOD that is sufficient to shift the available cavity modes in the spectral domain such that lasing at several different cavity modes sequentially is established as the gain signal is modulated.
Abstract:
According to one embodiment of the present invention, a frequency-converted laser source is provided wherein the wavelength conversion device comprises a plurality of waveguide components comprising respective input faces positioned in an effective focal field of the laser source. Individual ones of the waveguide components contribute different elements to a set of distinct wavelength conversion properties, defining a set of distinct wavelength conversion properties attributable to the waveguide components. The set of distinct wavelength conversion properties comprises properties representing phase matching wavelengths of the waveguide components, spectral widths of the waveguide components, conversion efficiency of the waveguide components, or combinations thereof. Additional embodiments are disclosed and claimed.
Abstract:
A swept wavelength imaging optical interrogation system and a method for using the same to interrogate one or more biosensors are described herein. The swept wavelength imaging optical interrogation system is built upon a swept wavelength optical interrogation technology where a 2-D label free image is extracted from a series of high speed spectral images of the biosensor(s) without the need of performing mechanical scanning.