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64 条记录 (耗时 0.029 秒)

    Synthesis of enantiomerically enriched 4-piperidinylglycine
    33.
    发明授权
    Synthesis of enantiomerically enriched 4-piperidinylglycine 失效
    对映体富集的4-哌啶基甘氨酸的合成

    公开(公告)号：US06670477B2

    公开(公告)日：2003-12-30

    申请号：US10090087

    申请日：2002-03-04

    申请人： Wen-Chung Shieh ,  Song Xue ,  Noela Marjory Reel ,  John Joseph Fitt

    发明人： Wen-Chung Shieh ,  Song Xue ,  Noela Marjory Reel ,  John Joseph Fitt

    IPC分类号： C07D21122

    CPC分类号： C07D211/34 ,  Y02P20/55

    摘要： A process for making enantiomerically enriched 4-piperidinylglycine having the formula (I), said process comprising (a) combining N-protected glycine ester with 4-piperidone to form didehydroamino acid ester; (b) reducing the didehydroamino acid ester with hydrogen gas in the presence of a rhodium catalyst selected from the group consisting of (R,R)-BPE-Rh; (S,S)-BPE-Rh; (R,R)-DuPHOS-Rh; (S,S)-DuPHOS-Rh; and combinations thereof; whereby a protected compound is formed; and (c) removing the protecting groups from the protected compound, whereby the 4-piperidinylglyeine having the formula (I) is formed, wherein X− is an anion wherein X is independently a halogen; and “*” designates an asymmetric carbon having (R)- or (S)-configuration. The process of the invention yields an enantiomerically enriched (R)-4-piperidineglycine or (S)-4-piperidineglycine.

    摘要翻译： 制备具有式（I）的对映体富集的4-哌啶基甘氨酸的方法，所述方法包括（a）将N-保护的甘氨酸酯与4-哌啶酮组合以形成二氢氨基酸酯; （b）在选自（R，R）-BPE-Rh的铑催化剂存在下，用氢气还原二氢氨基酸酯; （S，S）-BPE-Rh; （R，R）-DuPHOS-Rh; （S，S）-DuPHOS-Rh; 及其组合; 从而形成受保护的化合物; 和（c）从保护的化合物中除去保护基，由此形成具有式（I）的4-哌啶基甘氨酸，其中X 1是阴离子，其中X独立地是卤素; 和“*”表示具有（R） - 或（S） - 构型的不对称碳。 本发明的方法产生对映异构体富集的（R）-4-哌啶甘氨酸或（S）-4-哌啶甘氨酸。

    Analog multiplexer configured to reduce kickback perturbation in image sensor readout
    34.
    发明授权
    Analog multiplexer configured to reduce kickback perturbation in image sensor readout 有权
    模拟多路复用器配置为减少图像传感器读数中的反冲扰动

    公开(公告)号：US08184184B2

    公开(公告)日：2012-05-22

    申请号：US12329832

    申请日：2008-12-08

    申请人： Song Xue

    发明人： Song Xue

    IPC分类号： H04N3/14

    CPC分类号： H04N5/378 ,  H04N5/335

    摘要： An analog multiplexer is configured to multiplex a plurality of input analog signal channels into a single output analog signal channel. The analog multiplexer comprises a plurality of input sampling circuits associated with respective ones of the input analog signal channels and an amplifier having an input controllably connectable in turn to each of the input sampling circuits. The analog multiplexer is further configured to connect at least a given one of the input analog signal channels to a sampling element of its corresponding input sampling circuit at a predetermined time prior to connecting the sampling element of that input sampling circuit to the input of the amplifier. The predetermined time is less than a full clock cycle of a sampling clock of the amplifier. The analog multiplexer may be implemented in readout circuitry coupled to a pixel array in an image sensor.

    摘要翻译： 模拟多路复用器被配置为将多个输入模拟信号信道复用为单个输出模拟信号信道。 模拟多路复用器包括与相应输入模拟信号通道相关联的多个输入采样电路和具有可控制地连接到每个输入采样电路的输入的放大器。 模拟多路复用器还被配置为在将该输入采样电路的采样元件连接到放大器的输入端之前的预定时间将至少一个输入模拟信号通道中的给定输入模拟信号通道连接到其对应输入采样电路的采样元件 。 预定时间小于放大器采样时钟的整个时钟周期。 模拟多路复用器可以在耦合到图像传感器中的像素阵列的读出电路中实现。

    MAGNETIC SENSING DEVICE INCLUDING A SENSE ENHANCING LAYER
    36.
    发明申请
    MAGNETIC SENSING DEVICE INCLUDING A SENSE ENHANCING LAYER 有权
    包括感应增强层的磁感测装置

    公开(公告)号：US20100255349A1

    公开(公告)日：2010-10-07

    申请号：US12816967

    申请日：2010-06-16

    申请人： Zheng Gao ,  Brian W. Karr ,  Song Xue ,  Eric L. Granstrom ,  Khuong T. Tran ,  Yi X. Li

    发明人： Zheng Gao ,  Brian W. Karr ,  Song Xue ,  Eric L. Granstrom ,  Khuong T. Tran ,  Yi X. Li

    IPC分类号： G11B5/39

    CPC分类号： G01R33/093 ,  B82Y10/00 ,  B82Y25/00 ,  G11B5/3906 ,  G11B5/3909 ,  H01F10/3254 ,  H01F10/3272 ,  H01F10/3295 ,  H01L43/08 ,  Y10T428/1114 ,  Y10T428/1121

    摘要： A magnetic sensor includes a sensor stack having a first magnetic portion, a second magnetic portion, and a barrier layer between the first magnetic portion and the second magnetic portion. At least one of the first magnetic portion and the second magnetic portion includes a multilayer structure having a first magnetic layer having a positive magnetostriction adjacent to the barrier layer, a second magnetic layer, and an intermediate layer between the first magnetic layer and the second magnetic layer. The magnetic sensor has an MR ratio of at least about 80% when the magnetic sensor has a resistance-area (RA) product of about 1.0 Ω·μm2.

    摘要翻译： 磁传感器包括具有在第一磁性部分和第二磁性部分之间的第一磁性部分，第二磁性部分和阻挡层的传感器堆叠。 第一磁性部分和第二磁性部分中的至少一个包括多层结构，其具有与阻挡层相邻的具有正的磁致伸缩的第一磁性层，第二磁性层以及第一磁性层和第二磁性层之间的中间层 层。 当磁传感器的电阻面积（RA）积为约1.0＆OHgr·μm2时，磁传感器具有至少约80％的MR比。

    ANALOG MULTIPLEXER CONFIGURED TO REDUCE KICKBACK PERTURBATION IN IMAGE SENSOR READOUT
    38.
    发明申请
    ANALOG MULTIPLEXER CONFIGURED TO REDUCE KICKBACK PERTURBATION IN IMAGE SENSOR READOUT 有权
    模拟多路复用器被配置为减少图像传感器读数中的KICKBACK PERTURBATION

    公开(公告)号：US20100141822A1

    公开(公告)日：2010-06-10

    申请号：US12329832

    申请日：2008-12-08

    申请人： Song Xue

    发明人： Song Xue

    IPC分类号： H04N3/12 ,  H04J3/02

    CPC分类号： H04N5/378 ,  H04N5/335

    摘要： An analog multiplexer is configured to multiplex a plurality of input analog signal channels into a single output analog signal channel. The analog multiplexer comprises a plurality of input sampling circuits associated with respective ones of the input analog signal channels and an amplifier having an input controllably connectable in turn to each of the input sampling circuits. The analog multiplexer is further configured to connect at least a given one of the input analog signal channels to a sampling element of its corresponding input sampling circuit at a predetermined time prior to connecting the sampling element of that input sampling circuit to the input of the amplifier. The predetermined time is less than a full clock cycle of a sampling clock of the amplifier. The analog multiplexer may be implemented in readout circuitry coupled to a pixel array in an image sensor.

    摘要翻译： 模拟多路复用器被配置为将多个输入模拟信号信道复用为单个输出模拟信号信道。 模拟多路复用器包括与相应输入模拟信号通道相关联的多个输入采样电路和具有可控制地连接到每个输入采样电路的输入的放大器。 模拟多路复用器还被配置为在将该输入采样电路的采样元件连接到放大器的输入端之前的预定时间将至少一个输入模拟信号通道中的给定输入模拟信号通道连接到其对应输入采样电路的采样元件 。 预定时间小于放大器采样时钟的整个时钟周期。 模拟多路复用器可以在耦合到图像传感器中的像素阵列的读出电路中实现。

    Multi-Terminal Resistance Device
    40.
    发明申请
    Multi-Terminal Resistance Device 有权
    多端电阻器件

    公开(公告)号：US20100034011A1

    公开(公告)日：2010-02-11

    申请号：US12412644

    申请日：2009-03-27

    申请人： Haiwen Xi ,  Kaizhong Gao ,  Song Xue

    发明人： Haiwen Xi ,  Kaizhong Gao ,  Song Xue

    IPC分类号： G11C11/00 ,  H01L43/02

    CPC分类号： G11C11/5685 ,  G11C13/0007 ,  G11C13/003 ,  G11C2213/31 ,  G11C2213/32 ,  G11C2213/76 ,  H01L45/04 ,  H01L45/1206 ,  H01L45/122 ,  H01L45/146 ,  H01L45/147

    摘要： Embodiments of the invention provide a multi-terminal resistance device with first and second electrodes, a shared third electrode, and a resistance layer providing first and second current paths between the shared third electrode and the first and second electrodes, respectively. A current state of the device may be programmed by applying one or more electrical signals along the first and/or second current paths to change a resistance of the device. In some embodiments, applying an electrical signal may switch a junction resistance of the first and/or second electrodes and the resistance layer between two or more resistance values. The device may include a shared fourth electrode to provide extra programming capability. In some embodiments, the device may be used to store a data state, to determine a count of multiple electrical signals, or to perform a logic operation between two electrical signals.

    摘要翻译： 本发明的实施例提供了具有第一和第二电极，共享第三电极和在共享的第三电极和第一和第二电极之间分别提供第一和第二电流路径的电阻层的多端电阻装置。 可以通过沿着第一和/或第二电流路径施加一个或多个电信号来改变器件的电阻来编程器件的当前状态。 在一些实施例中，施加电信号可以将第一和/或第二电极和电阻层的结电阻切换到两个或更多个电阻值之间。 该设备可以包括共享的第四电极以提供额外的编程能力。 在一些实施例中，该设备可以用于存储数据状态，以确定多个电信号的计数，或者在两个电信号之间执行逻辑运算。