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公开(公告)号:US20070015723A1
公开(公告)日:2007-01-18
申请号:US11436901
申请日:2006-05-17
申请人: Ronnie Hanecak , Kevin Anderson , C. Bennett , Ming-Yi Chiang , Vickie Brown-Driver , David Ecker , Timothy Vickers , Jacqueline Wyatt
发明人: Ronnie Hanecak , Kevin Anderson , C. Bennett , Ming-Yi Chiang , Vickie Brown-Driver , David Ecker , Timothy Vickers , Jacqueline Wyatt
IPC分类号: A61K48/00
CPC分类号: A61K31/70 , A61K38/00 , C07H21/00 , C12N15/1133 , C12N15/1137 , C12N15/115 , C12N15/117 , C12N2310/151 , C12N2310/18 , C12N2310/315 , C12N2310/321 , C12N2310/341 , C12N2310/346 , C12Q1/701 , C12Y207/07049 , C12Y301/01004 , C12N2310/3521
摘要: Modified oligonucleotides having a conserved G4 sequence and a sufficient number of flanking nucleotides to significantly inhibit the activity of a virus or phospholipase A2 or to modulate the telomere length of a chromosome are provided. G4 quartet oligonucleotide structures are also provided. Methods of prophylaxis, diagnostics and therapeutics for viral-associated diseases and diseases associated with elevated levels of phospholipase A2 are also provided. Methods of modulating telomere length of a chromosome are also provided; modulation of telomere length is believed to play a role in the aging process of a cell and in control of malignant cell growth.
摘要翻译: 修饰的寡核苷酸具有保守的GAT4序列和足够数量的侧翼核苷酸以显着抑制病毒或磷脂酶A 2的活性或调节染色体的端粒长度 被提供。 还提供了G 4四重寡核苷酸结构。 还提供了与升高的磷脂酶A 2 2水平相关的病毒相关疾病和疾病的预防,诊断和治疗方法。 还提供了调节染色体端粒长度的方法; 相信端粒长度的调节在细胞的衰老过程中和恶性细胞生长的控制中起作用。
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公开(公告)号:US20050217558A1
公开(公告)日:2005-10-06
申请号:US10517685
申请日:2003-06-13
申请人: Robert Fitzer , G. Bommarito , Richard Crone , Jeffrey McCutcheon , Kevin Anderson , Russell Birkholz , Zhiming Zhou
发明人: Robert Fitzer , G. Bommarito , Richard Crone , Jeffrey McCutcheon , Kevin Anderson , Russell Birkholz , Zhiming Zhou
CPC分类号: G01P15/036 , G01P15/06 , H04M1/18
摘要: A shock indicator is described comprising (A) a base having a first side and a second side; (B) an indicator associated with the first side of the base, the indicator comprising a plurality of indicator subparts, the subparts comprising solid material arranged (i) in a first configuration when the shock indicator is in a first state prior to a shock event, and (ii) in a second configuration when the shock indicator is in a second state following a shock event; and (C) means associated with the second side of the base for attachment of the shock indicator to a surface. A method of manufacture is also provided.
摘要翻译: 描述的冲击指示器包括:(A)具有第一侧和第二侧的底座; (B)与所述基座的第一侧相关联的指示器,所述指示器包括多个指示器子部件,所述子部件包括固体材料,所述固体材料布置成(i)当所述休克指示器在冲击事件之前处于第一状态时处于第一配置 ,以及(ii)当所述休克指示器处于休克事件之后的第二状态时处于第二配置; 和(C)与基座的第二侧相关联的装置,用于将冲击指示器附接到表面。 还提供了一种制造方法。
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公开(公告)号:US20050191400A1
公开(公告)日:2005-09-01
申请号:US11112401
申请日:2005-04-22
IPC分类号: A21D2/18 , A23L1/10 , A23L1/308 , A23L1/314 , C08B30/10 , C08L5/14 , D21C3/04 , D21C5/00 , D21C9/14 , D21C9/16 , D21H11/12 , D21H11/20 , D21H17/02 , D21H21/52 , D21H11/00
CPC分类号: D21H17/02 , A21D2/188 , A23L7/115 , A23L13/426 , A23L33/24 , C08B30/10 , C08L5/14 , D01C1/02 , D06L4/13 , D21C3/04 , D21C3/12 , D21C5/00 , D21H11/12 , D21H11/20 , D21H21/52
摘要: The disclosure provides a process of modifying a seed based fiber (SBF) to form an enhanced fiber additive (EFA). The process includes an acid treatment step and optionally at least one fiber modification step. Preferred EFA products and uses are described.
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公开(公告)号:US20050181491A1
公开(公告)日:2005-08-18
申请号:US11035835
申请日:2005-01-14
申请人: L. Eirich , Kevin Anderson , Jeffrey Gates , C. Wilson , Manfred Biermann , Gilbert Vice
发明人: L. Eirich , Kevin Anderson , Jeffrey Gates , C. Wilson , Manfred Biermann , Gilbert Vice
摘要: A bioprocess for producing carboxylic acids, alcohols and aldehydes is provided by culturing Candida sp. in a fermentation medium containing various defined substrates.
摘要翻译: 生产羧酸,醇和醛的生物工艺是通过培养念珠菌来提供的。 在含有各种定义的底物的发酵培养基中。
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公开(公告)号:US20050084940A1
公开(公告)日:2005-04-21
申请号:US10756240
申请日:2004-01-13
申请人: Kevin Anderson , J. Douglas Wenzel
发明人: Kevin Anderson , J. Douglas Wenzel
IPC分类号: C12P7/44 , C12P7/46 , C12P7/64 , C22B20060101
CPC分类号: C12P7/6409 , C12P7/44 , C12P7/46
摘要: Biooxidation reactions can be controlled by a method which comprises the steps of: (1) independently adding a substrate and a co-substrate at predetermined rates to a bioxidation reaction mixture comprised of a biocatalyst; (2) measuring the oxygen consumption rate and carbon dioxide evolution rate from the reaction mixture; (3) determining the instantaneous rates of substrate and cosubstrate consumption by solving simultaneous equations relating carbon dioxide evolution rate and oxygen consumption rate to the substrate oxidation stoichiometry, the cosubstrate combustion stoichiometry, and optionally the biomass formation stoichiometry; (4) simultaneously adjusting the substrate and cosubstrate addition rates to the rates of substrate oxidation and cosubstrate consumption in order to maximize the rate of product formation while simultaneously minimizing the rate of cosubstrate usage. The method provides a rapid means of controlling fed-batch biooxidation reactions which can employ in-line techniques and is broadly applicable for diverse oxidation reactions.
摘要翻译: 生物氧化反应可以通过一种方法来控制,该方法包括以下步骤:(1)以包含生物催化剂的生物氧化反应混合物以预定速率独立地加入底物和共底物; (2)从反应混合物中测量氧气消耗速率和二氧化碳释放速率; (3)通过求解将二氧化碳进化速率和氧耗率与二氧化碳排放速率和氧消耗速率相关的联立方程与底物氧化化学计量法,同位素燃烧化学计量法和任选的生物质形成化学计量法来确定底物和辅助消耗的瞬时速率; (4)同时调整衬底并将衬底加入速率与底物氧化和辅助消耗的速率进行调和,以最大限度地提高产物形成速率,同时最大限度地降低衬底使用率。 该方法提供了控制补料分批生物氧化反应的快速方法,其可以使用在线技术并且广泛适用于多种氧化反应。
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公开(公告)号:US11761061B2
公开(公告)日:2023-09-19
申请号:US16132231
申请日:2018-09-14
申请人: Orlando Rios , Hunter B. Henderson , David Weiss , Scott McCall , Eric Thomas Stromme , Zachary Cole Sims , Ryan Ott , Fanqiang Meng , Michael Kesler , Kevin Anderson
发明人: Orlando Rios , Hunter B. Henderson , David Weiss , Scott McCall , Eric Thomas Stromme , Zachary Cole Sims , Ryan Ott , Fanqiang Meng , Michael Kesler , Kevin Anderson
摘要: Disclosed herein are embodiments of aluminum-based alloys having improved intergranular corrosion resistance. Methods of making and using the disclosed alloy embodiments also are disclosed herein.
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公开(公告)号:US20230248166A1
公开(公告)日:2023-08-10
申请号:US18105224
申请日:2023-02-02
申请人: Kevin Anderson
发明人: Kevin Anderson
IPC分类号: A47G19/26
CPC分类号: A47G19/26 , A47G2400/061
摘要: A cake saver device for preventing contaminants from coming into contact with a cake when blowing out one or more candles is presented. The cake saver device is useful for providing a stand/mount to hold the candles at a location away from the cake for preventing contaminants from spittle expectorated while blowing out the one or more candles from coming into contact with the cake. Also, the cake saver device provides peace of mind as a cost efficient and reusable device.
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公开(公告)号:US09034006B2
公开(公告)日:2015-05-19
申请号:US11607638
申请日:2006-12-01
申请人: Chris Quinn , Steve Zaver , Kevin Anderson
发明人: Chris Quinn , Steve Zaver , Kevin Anderson
IPC分类号: A61M29/00 , A61B17/221 , A61B17/12 , A61B17/3205 , A61B17/22
CPC分类号: A61B17/12122 , A61B17/12022 , A61B17/12172 , A61B17/221 , A61B17/32056 , A61B2017/12054 , A61B2017/22035
摘要: A retrieval portion is attached to an implantable device to facilitate retrieval of the implantable device in the unlikely event of embolization. The retrieval portion may comprise one or more loops, or a plurality of extensions. Methods of retrieving an implantable device are disclosed. Various adapters are disclosed for use with a conventional snare for grasping an implantable device.
摘要翻译: 检索部分连接到可植入装置,以便在不太可能发生栓塞的情况下便于可植入装置的取出。 检索部分可以包括一个或多个循环或多个扩展。 公开了检索可植入装置的方法。 公开了与用于抓握可植入装置的常规圈套一起使用的各种适配器。
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公开(公告)号:US08826375B2
公开(公告)日:2014-09-02
申请号:US12102670
申请日:2008-04-14
申请人: Mark Smith , Kevin Anderson , Michael Harvey
发明人: Mark Smith , Kevin Anderson , Michael Harvey
CPC分类号: H04L63/105 , G06Q10/10
摘要: A user annotates a shared document with text, sound, images, video, an e-mail message, graphics, screen snapshots, web site snapshots to share with others. The document and its annotations are stored in a digital object repository to which other users have access. Within the closed collaboration system, only users who are authenticated may upload digital objects, annotate digital objects and view objects and their annotations. The user sends a message to other users to invite them to view the object and its annotations and to add their own annotations. An annotated object generates an alert for all of the invited users. A remote authentication gateway authenticates users and has a repository for user metadata. Digital object repositories are separate from the authentication gateway, thus providing for disintermediation of the user metadata from the digital object data. The collaboration system may be hosted by a third party on a server computer available over the Internet that displays a web site. A user is not required to have collaboration system software on his or her computer and may annotate any image on the web site for later viewing by other users of the web site.
摘要翻译: 用户使用文本,声音,图像,视频,电子邮件消息,图形,屏幕快照,与其他人共享的网站快照来注释共享文档。 文档及其注释存储在其他用户可访问的数字对象存储库中。 在封闭的协作系统中,只有经过身份验证的用户才能上传数字对象,注释数字对象,查看对象及其注释。 用户向其他用户发送消息,邀请他们查看对象及其注释,并添加自己的注释。 注释对象会为所有受邀用户生成警报。 远程验证网关对用户进行身份验证,并具有用户元数据的存储库。 数字对象存储库与认证网关分离,从而提供用户元数据从数字对象数据的中介。 协作系统可以由可通过因特网可用的显示网站的服务器计算机上的第三方托管。 用户不需要在他或她的计算机上拥有协作系统软件,并且可以在网站上注释任何图像,以供该网站的其他用户稍后查看。
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公开(公告)号:US20120035320A1
公开(公告)日:2012-02-09
申请号:US13079580
申请日:2011-04-04
申请人: Kevin G. Rice , Nicholas J. Baumhover , Christian A. Fernandez , Kevin Anderson , Mark D. Ericson , Jason T. Duskey , Koby Kizzire , Sanjib Khargharia , Samuel T. Crowley
发明人: Kevin G. Rice , Nicholas J. Baumhover , Christian A. Fernandez , Kevin Anderson , Mark D. Ericson , Jason T. Duskey , Koby Kizzire , Sanjib Khargharia , Samuel T. Crowley
IPC分类号: C08G65/333 , C07K4/00 , C07K14/00 , C07K19/00 , C12N9/96
CPC分类号: C07K9/001 , A61K47/64 , A61K47/6455 , A61K48/0025 , A61K48/0041 , C07K2319/00 , C07K2319/80 , C12N15/87
摘要: The present invention provides nucleic acid delivery polyplex complexes and anionic open polyplexes comprising a nucleic acid molecule reversibly bound to one or more of nucleic acid delivery polyplex complexes.
摘要翻译: 本发明提供核酸递送多聚复合物和阴离子开放复合物,其包含可逆结合于一个或多个核酸递送多聚复合物的核酸分子。
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