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31.发明申请Methods for positioning a load-bearing component of an orthopedic implant device by inserting a malleable device that hardens in vivo 有权通过插入在体内硬化的可延展装置来定位矫形植入装置的承重部件的方法公开(公告)号：US20080154367A1
公开(公告)日：2008-06-26
申请号：US11643177
申请日：2006-12-21
CPC分类号： A61B17/7032 , A61B17/7013 , A61B17/80 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61B2017/00831 , A61F2/441 , A61F2/442 , A61F2/4425 , A61F2/4465 , A61F2/447 , A61F2002/30062 , A61F2002/30579 , A61F2002/30583 , A61F2002/30649 , A61F2002/30841 , A61F2002/30884 , A61F2210/0004 , A61F2210/0085
摘要： A device is provided that is non-rigid, i.e., flexible and/or malleable, in a first form, and then transformable after insertion to an in vivo site into a rigid, or hardened, form; a cure-initiating energy is applied to the device; and the device is then positioned in the in vivo site where it hardens to provide a load-bearing function or other structural and/or mechanical function. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material.
摘要翻译： 提供了以第一种形式是非刚性的，即柔性的和/或可延展的装置，然后在插入到体内部位之后可变形为刚性或硬化的形式; 对装置施加固化起始能量; 然后将该装置定位在体内部位，在那里其硬化以提供承载功能或其它结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。
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公开(公告)号：US20080058932A1
公开(公告)日：2008-03-06
申请号：US11493783
申请日：2006-07-26
IPC分类号： A61F2/44
CPC分类号： A61F2/4425 , A61B17/7013 , A61B17/7031 , A61B17/7059 , A61B17/8085 , A61B17/864 , A61B2017/00831 , A61F2/44 , A61F2/441 , A61F2/4455 , A61F2/4465 , A61F2/447 , A61F2002/2835 , A61F2002/30062 , A61F2002/3009 , A61F2002/302 , A61F2002/30537 , A61F2002/30563 , A61F2002/30565 , A61F2002/30583 , A61F2002/30586 , A61F2002/30884 , A61F2002/444 , A61F2210/0004 , A61F2210/0085 , A61F2230/0065 , A61F2250/0004 , A61F2250/0091
摘要： Orthopedic devices include a body having an internal chamber housing a curable material. At least a portion of the body provides a barrier member structured to transmit an energy source therethrough to contact the curable material disposed in the internal chamber. The curable material is provided in a first form that provides flexibility to the body and is structured to rigidize in a second form when exposed to the energy source.
摘要翻译： 矫形装置包括具有容纳可固化材料的内室的主体。 身体的至少一部分提供了阻挡构件，其构造成透过其中的能量源以与设置在内部腔室中的可固化材料接触。 可固化材料以第一形式提供，其向身体提供柔性，并且被构造成当暴露于能量源时以第二形式刚性化。
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公开(公告)号：US07204851B2
公开(公告)日：2007-04-17
申请号：US10717687
申请日：2003-11-20
申请人： Hai H. Trieu , Jeff R. Justis , Roy Lim
发明人： Hai H. Trieu , Jeff R. Justis , Roy Lim
CPC分类号： A61F2/4611 , A61B2017/0256 , A61F2/30767 , A61F2/30965 , A61F2/441 , A61F2/442 , A61F2002/2817 , A61F2002/30056 , A61F2002/30062 , A61F2002/3008 , A61F2002/30092 , A61F2002/30133 , A61F2002/30179 , A61F2002/302 , A61F2002/30224 , A61F2002/30291 , A61F2002/30563 , A61F2002/30596 , A61F2002/30604 , A61F2002/30677 , A61F2002/30719 , A61F2002/30827 , A61F2002/30838 , A61F2002/30891 , A61F2002/30906 , A61F2002/30909 , A61F2002/30925 , A61F2002/30957 , A61F2002/4415 , A61F2002/444 , A61F2002/4495 , A61F2002/4622 , A61F2002/4627 , A61F2002/4628 , A61F2210/0004 , A61F2210/0014 , A61F2230/0015 , A61F2230/0058 , A61F2230/0065 , A61F2230/0069 , A61F2230/0091 , A61F2250/0032 , A61F2250/0092 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023
摘要： A method for implanting a prosthetic spinal disc nucleus in an intervertebral disc nucleus space generally includes: (a) making a hole in the annulus of a disc, with the hole having an undilated size that is smaller than the cross-sectional size of a folded prosthetic disc nucleus; (b) using an implant instrument to dilate the hole in the disc annulus; (c) using the implant instrument to pass a straightened prosthetic disc nucleus through the dilated hole and into the disc nucleus space; (d) withdrawing the implant instrument and allowing the hole in the disc annulus to return to a size smaller that its dilated size; and (e) causing or allowing the prosthetic disc nucleus to assume a folded configuration with a cross-sectional size that is larger than its straightened size. A device for use in the method is also disclosed.
摘要翻译： 用于在椎间盘细胞核空间中植入假肢脊椎椎间盘的方法通常包括：（a）在椎间盘的环空中形成孔，其中孔具有未折叠的尺寸，小于折叠的横截面尺寸 假体椎间盘核; （b）使用植入器械来扩张椎间盘环中的孔; （c）使用植入器械使经过扩张的假体椎间盘核穿过扩张的孔并进入椎间盘细胞核空间; （d）撤回植入器械并允许椎间盘环中的孔返回到其扩大的尺寸更小的尺寸; 和（e）引起或允许假体椎间盘细胞核具有横截面尺寸大于其矫直尺寸的折叠构型。 还公开了用于该方法的装置。
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34.发明授权Methods for positioning a load-bearing component of an orthopedic implant device by inserting a malleable device that hardens in vivo 有权通过插入在体内硬化的可延展装置来定位矫形植入装置的承重部件的方法公开(公告)号：US08663328B2
公开(公告)日：2014-03-04
申请号：US11643177
申请日：2006-12-21
IPC分类号： A61F2/44
CPC分类号： A61B17/7032 , A61B17/7013 , A61B17/80 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61B2017/00831 , A61F2/441 , A61F2/442 , A61F2/4425 , A61F2/4465 , A61F2/447 , A61F2002/30062 , A61F2002/30579 , A61F2002/30583 , A61F2002/30649 , A61F2002/30841 , A61F2002/30884 , A61F2210/0004 , A61F2210/0085
摘要： A device is provided that is non-rigid, i.e., flexible and/or malleable, in a first form, and then transformable after insertion to an in vivo site into a rigid, or hardened, form; a cure-initiating energy is applied to the device; and the device is then positioned in the in vivo site where it hardens to provide a load-bearing function or other structural and/or mechanical function. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material.
摘要翻译： 提供了以第一种形式是非刚性的，即柔性的和/或可延展的装置，然后在插入到体内部位之后可变形为刚性或硬化的形式; 对装置施加固化起始能量; 然后将该装置定位在体内部位，在那里其硬化以提供承载功能或其它结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。
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公开(公告)号：US08632524B2
公开(公告)日：2014-01-21
申请号：US11471993
申请日：2006-06-21
CPC分类号： A61F2/4601 , A61B17/7098 , A61B17/8836 , A61F2002/30583 , A61F2002/4688 , A61F2002/4696 , A61F2210/0085 , A61M2210/1003
摘要： An injectable biocompatible material delivery system is disclosed and can include an injector and a material delivery cannula that can be in fluid communication with the injector. Further, the injectable biocompatible material delivery system can include a light source that can be configured to emit light to at least a portion of the injector, at least a portion of the material delivery cannula, or a combination thereof. Further, the light source can be configured to activate an injectable biocompatible material as it moves through the system.
摘要翻译： 公开了可注射的生物相容性材料输送系统，并且可以包括可以与注射器流体连通的注射器和材料输送套管。 此外，可注射的生物相容性材料输送系统可以包括光源，其可被配置为向喷射器的至少一部分，材料输送套管的至少一部分或其组合发光。 此外，光源可以被配置为在可注射的生物相容性材料移动通过系统时激活。
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36.发明申请Curable orthopedic implant devices configured to harden after placement in vivo by application of a cure-initiating energy before insertion 有权该矫形矫形植入装置被配置为在插入之后通过施加固化引发能量在体内放置后硬化公开(公告)号：US20080154368A1
公开(公告)日：2008-06-26
申请号：US11643489
申请日：2006-12-21
CPC分类号： A61B17/866 , A61B17/7013 , A61B17/7032 , A61B17/7049 , A61B17/80 , A61B17/8605 , A61B17/8625 , A61F2/441 , A61F2/4425 , A61F2/4455 , A61F2/4465 , A61F2/447 , A61F2002/2835 , A61F2002/30062 , A61F2002/302 , A61F2002/30225 , A61F2002/30545 , A61F2002/30556 , A61F2002/30583 , A61F2002/30677 , A61F2002/30884 , A61F2002/3092 , A61F2002/444 , A61F2002/4495 , A61F2002/465 , A61F2210/0004 , A61F2210/0085 , A61F2230/0065 , A61F2230/0069 , A61F2250/0009 , A61F2250/001
摘要： An orthopedic implant device is non-rigid, i.e., flexible and/or malleable, in a first form for insertion into a desired in vivo site, and then transformable into a rigid, or hardened, form for providing a load-bearing function or providing other structural and/or mechanical function after implant. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after insertion to an in vivo location as a result of application of a cure-initiating energy to the material prior to insertion. Related methods and kits are also provided.
摘要翻译： 整形外科植入物装置是非刚性的，即柔性和/或可延展的，以第一形式插入所需的体内部位，然后可变形成刚性或硬化的形式，以提供承载功能或提供 植入后的其他结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在插入到体内位置之后以第二种形式刚性化，这是由于在插入之前向该材料施加固化引发能量。 还提供了相关方法和试剂盒。
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公开(公告)号：US20070299426A1
公开(公告)日：2007-12-27
申请号：US11471993
申请日：2006-06-21
CPC分类号： A61F2/4601 , A61B17/7098 , A61B17/8836 , A61F2002/30583 , A61F2002/4688 , A61F2002/4696 , A61F2210/0085 , A61M2210/1003
摘要： An injectable biocompatible material delivery system is disclosed and can include an injector and a material delivery cannula that can be in fluid communication with the injector. Further, the injectable biocompatible material delivery system can include a light source that can be configured to emit light to at least a portion of the injector, at least a portion of the material delivery cannula, or a combination thereof. Further, the light source can be configured to activate an injectable biocompatible material as it moves through the system.
摘要翻译： 公开了可注射的生物相容性材料输送系统，并且可以包括可以与注射器流体连通的注射器和材料输送套管。 此外，可注射的生物相容性材料输送系统可以包括光源，其可被配置为向喷射器的至少一部分，材料输送套管的至少一部分或其组合发光。 此外，光源可以被配置为在可注射的生物相容性材料移动通过系统时激活。
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公开(公告)号：US20070299520A1
公开(公告)日：2007-12-27
申请号：US11474912
申请日：2006-06-26
IPC分类号： A61F2/28
CPC分类号： A61F2/30767 , A61B17/86 , A61F2/3094 , A61F2/36 , A61F2/3662 , A61F2/367 , A61F2/38 , A61F2/40 , A61F2/442 , A61F2002/30064 , A61F2002/30906 , A61F2002/30925 , A61F2002/3611 , A61F2002/3625 , A61F2310/00796 , A61F2310/00958 , A61F2310/00976 , A61F2310/00982 , A61F2310/00994 , A61L2/07 , A61L2/081 , A61L2/082 , A61L2/18 , A61L2202/24 , C23C28/00
摘要： A device includes a sterilizing system configured to sterilize an implantable device and includes a coating system configured to apply an osteal functional coating to the implantable device.
摘要翻译： 一种装置包括灭菌系统，其构造成对可植入装置进行灭菌并且包括被配置为将骨功能涂层施加到可植入装置的涂层系统。
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39.发明授权公开(公告)号：US09414864B2
公开(公告)日：2016-08-16
申请号：US12409089
申请日：2009-04-15
申请人： Hai H. Trieu
发明人： Hai H. Trieu
CPC分类号： A61B17/7059 , A61B17/8042 , A61B2017/00004 , A61B2017/00951 , A61K9/0024 , A61K47/24 , A61K47/32 , A61K47/34
摘要： An anterior spinal plate has affixed to at least a portion of a surface thereof at least one preformed drug-eluting device fabricated from a drug-eluting matrix containing at least one elutable drug.
摘要翻译： 前脊椎板已经固定在其表面的至少一部分上，至少一个预先形成的药物洗脱装置由含有至少一种可洗脱药物的药物洗脱基质制备。
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公开(公告)号：US09072546B2
公开(公告)日：2015-07-07
申请号：US12869245
申请日：2010-08-26
申请人： Hai H. Trieu , Jon A. Harmon
发明人： Hai H. Trieu , Jon A. Harmon
IPC分类号： A61B17/70
CPC分类号： A61B17/7032 , A61B17/7004 , A61B17/7011 , A61B17/7019 , A61B17/7026 , A61B17/7031 , A61B17/7035
摘要： A spinal construct for implantation in a patient to provide stabilization to spinal structure with improved load sharing includes a flexible spinal rod having a first end and a second end, the spinal rod being configured to provide stabilization to spinal structure. It also includes a first bone fastener configured to securely attach to the flexible spinal rod and a second bone fastener configured to securely attach to the flexible spinal rod. The second bone fastener is a dynamic fastener arranged to provide motion in one direction more than another direction. The flexible spinal rod and the second bone fastener are oriented to cooperate in a manner that achieves load sharing by dynamically flexing under applied loads in a manner that distributes stresses and strains between the flexible spinal rod and the second bone fastener.
摘要翻译： 用于植入患者以提供具有改善的负荷共享的脊柱结构的稳定性的脊柱构造包括具有第一端和第二端的柔性脊柱杆，所述脊柱杆被配置为提供对脊柱结构的稳定性。 其还包括构造成牢固地附接到柔性脊椎杆的第一骨紧固件和构造成牢固地附接到柔性脊椎杆的第二骨紧固件。 第二骨紧固件是被设置为沿一个方向提供比另一个方向更大的运动的动态紧固件。 柔性脊柱杆和第二骨紧固件被定向成以通过在施加的负载下动态地弯曲以在柔性脊骨杆和第二骨紧固件之间分布应力和应变的方式来实现负载共享的方式协作。
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