利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

229 条记录 (耗时 0.025 秒)

    Dominant negative mutants of IRS-1 and uses thereof
    31.
    发明授权
    Dominant negative mutants of IRS-1 and uses thereof 失效
    IRS-1的主要负性突变体及其用途

    公开(公告)号：US06528479B1

    公开(公告)日：2003-03-04

    申请号：US08964296

    申请日：1997-11-04

    申请人： Shinji Tanaka ,  Jack R. Wands

    发明人： Shinji Tanaka ,  Jack R. Wands

    IPC分类号： A01N3718

    CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K48/00

    摘要： Dominant negative mutants of mammalian IRS-1 proteins and therapeutic compositions containing such mutants. Also featured are methods of using the dominant negative mutants to inhibit tyrosyl phosphorylation of endogenous IRS-1 in mammalian cells and methods of treating a mammalian malignancy in which tyrosyl phosphorylation of endogenous IRS-1 plays a causative role.

    摘要翻译： 哺乳动物IRS-1蛋白的主要负性突变体和含有此类突变体的治疗组合物。 还特征在于使用显性负突变体抑制哺乳动物细胞中内源性IRS-1的酪氨酰磷酸化的方法以及治疗哺乳动物恶性肿瘤的方法，其中内源性IRS-1的酪氨酰磷酸化起着原因作用。

    Artificially patinated copper material
    35.
    发明授权
    Artificially patinated copper material 失效
    人造铜板材料

    公开(公告)号：US6063480A

    公开(公告)日：2000-05-16

    申请号：US104009

    申请日：1998-06-24

    申请人： Takashi Hokazono ,  Shinji Tanaka

    发明人： Takashi Hokazono ,  Shinji Tanaka

    IPC分类号： C23C22/52 ,  B44F9/10 ,  C23C22/63 ,  B32B3/00

    CPC分类号： C23C22/63 ,  B44F9/10 ,  Y10T428/24893 ,  Y10T428/24909 ,  Y10T428/256 ,  Y10T428/265

    摘要： An artificially patinated copper plate in which a copper sulfide layer 2 is formed on the surface of a copper base plate 1 by sulfiding for coating the same, and the copper sulfide layer 2 having an artificially patinated layer 3 is formed distributed and bonded thereon by spraying a resin solution mixed with basic copper carbonate constituting the main component of natural patina. The percentage of the area occupied by the artificially patinated layer 3 on the copper sulfide layer 2 is most preferably 25% to 80% and the thickness of the copper sulfide layer 2 is most preferably 0.1 to 0.5 .mu.m.

    摘要翻译： 在铜基板1的表面上通过硫化涂覆铜硫化物层2的人造铜板，通过喷涂形成分散并结合在其上的具有人造板层3的硫化铜层2 与构成天然蛋白的主要成分的碱性碳酸铜混合的树脂溶液。 硫化铜层2上人造涂层3所占的面积百分比最优选为25％〜80％，硫化铜层2的厚度最优选为0.1〜0.5μm。

    Semiconductor memory device
    36.
    发明授权
    Semiconductor memory device 失效
    半导体存储器件

    公开(公告)号：US6002621A

    公开(公告)日：1999-12-14

    申请号：US33657

    申请日：1998-03-03

    申请人： Shinji Tanaka ,  Koji Tanaka ,  Mikio Asakura ,  Kenichi Yasuda

    发明人： Shinji Tanaka ,  Koji Tanaka ,  Mikio Asakura ,  Kenichi Yasuda

    IPC分类号： G11C29/24 ,  G11C7/00

    CPC分类号： G11C29/24

    摘要： Normal column selection signal switching device (20) is provided to switch a signal outputted from normal column selection signal generating device (19) in response to a test-mode signal (TMC1). Even if the normal column selection signal generating device (19) outputs a signal to disable a normal column decoder (3), the normal column selection signal switching device (20) switches the signal to enable the normal column decoder (3) to operate in the test operation. Having this configuration, a semiconductor memory device enables writing of data into all the normal memory cells even after some of the normal memory cells are replaced by spare memory cells.

    摘要翻译： 提供正常列选择信号切换装置（20）以响应于测试模式信号（TMC1）切换从正常列选择信号发生装置（19）输出的信号。 即使正常列选择信号生成装置（19）输出禁止通常的列解码器（3）的信号，通常的列选择信号切换装置（20）切换信号，使通常的列解码器（3）能够工作 测试操作。 具有这种配置，半导体存储器件即使在由备用存储器单元代替一些正常存储器单元之后，也能够将数据写入所有正常存储单元。

    Secondary battery protection device from overcharge/overdischarge
    38.
    发明授权
    Secondary battery protection device from overcharge/overdischarge 失效
    二次电池保护装置过充电/过放电

    公开(公告)号：US5896025A

    公开(公告)日：1999-04-20

    申请号：US777965

    申请日：1996-12-24

    申请人： Takeshi Yamaguchi ,  Yosifumi Sakaguchi ,  Shinji Tanaka ,  Takehisa Yokohama ,  Kouichi Horisaki ,  Eiji Matsumasa

    发明人： Takeshi Yamaguchi ,  Yosifumi Sakaguchi ,  Shinji Tanaka ,  Takehisa Yokohama ,  Kouichi Horisaki ,  Eiji Matsumasa

    IPC分类号： H01M10/44 ,  H02H7/18 ,  H02J7/00 ,  H02J7/10

    CPC分类号： H02J7/0031

    摘要： A protection circuit device for protecting a secondary battery from an overcharge and/or an overdischarge has first and second terminals, across which a charger and a load are alternatively connectable. A first switch and/or a second switch may be provided in series with the secondary battery between the first and second terminals. In a charging operation mode, the second switch is kept conductive. A charging operation is performed with the first switch made conductive. When the battery is overcharged for some reasons, the first switch is turned off. Upon connection of a load across the first and second terminals, the first switch is restored to a conductive state for a discharging operation which releases the battery from an overdischarge state. In a discharging operation mode, the first switch is kept conductive. A discharge operation is performed with the second switch made conductive. When the battery is overdischarged, the second switch is caused to remain conductive even after commencement of the overdischarge, so that the battery can continue the discharge operation if the temporary overdischarge does not last longer than the predetermined period of time.

    摘要翻译： 用于保护二次电池免受过充电和/或过放电的保护电路装置具有第一和第二端子，充电器和负载可交替地连接在该端子上。 可以在第一和第二端子之间与二次电池串联地提供第一开关和/或第二开关。 在充电操作模式中，第二开关保持导通。 在第一开关导通的情况下执行充电操作。 当电池由于某些原因过充电时，第一个开关关闭。 当跨越第一和第二端子的负载连接时，第一开关被恢复到用于使电池从过放电状态释放的放电操作的导通状态。 在放电操作模式中，第一开关保持导通。 在第二开关导通时执行放电操作。 当电池过度放电时，即使在过放电开始之后，第二开关也保持导通，使得如果临时过放电持续时间比预定时间长，电池可以继续放电操作。

    Cleaning solution for contact lens exhibiting excellent detergency
    40.
    发明授权
    Cleaning solution for contact lens exhibiting excellent detergency 失效
    具有优异洗涤力的隐形眼镜清洁液

    公开(公告)号：US5840671A

    公开(公告)日：1998-11-24

    申请号：US569450

    申请日：1995-12-08

    申请人： Atumi Fujimura ,  Kaoru Kamiya ,  Shinji Tanaka

    发明人： Atumi Fujimura ,  Kaoru Kamiya ,  Shinji Tanaka

    IPC分类号： G02C13/00 ,  C11D1/10 ,  C11D1/14 ,  C11D1/22 ,  C11D1/29 ,  C11D1/75 ,  C11D1/83 ,  C11D1/86 ,  C11D3/00 ,  C11D1/12 ,  C11D1/62 ,  C11D1/94

    CPC分类号： C11D1/83 ,  C11D3/0078 ,  C11D1/10 ,  C11D1/146 ,  C11D1/22 ,  C11D1/29 ,  C11D1/75

    摘要： A cleaning solution for cleaning a contact lens, which includes at least one first component each consisting of a tertiary amine oxide which is represented by the formula given in the specification and at least one second component each consisting of an anionic surface active agent in the form of a triethanolamine salt, a total content of the at least one first component and the at least one second component being within a range of 0.1-20% by weight, a ratio of a total content of the at least one first component to a total content of the at least one second component being within a range from 1/4 to 30/1.

    摘要翻译： 一种用于清洁隐形眼镜的清洁溶液，其包括至少一种第一组分，每个第一组分各自由说明书中给出的分子式表示的叔胺氧化物和至少一种第二组分，每个第二组分由阴离子表面活性剂形式 的三乙醇胺盐，所述至少一种第一组分和至少一种第二组分的总含量在0.1-20重量％的范围内，所述至少一种第一组分的总含量与总量的比例 所述至少一个第二组分的含量在1/4至30/1的范围内。