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197 条记录 (耗时 0.021 秒)

    Polishing apparatus
    31.
    发明授权
    Polishing apparatus 失效
    抛光设备

    公开(公告)号：US5679063A

    公开(公告)日：1997-10-21

    申请号：US590477

    申请日：1996-01-24

    申请人： Norio Kimura ,  You Ishii ,  Hozumi Yasuda ,  Koji Saito ,  Masako Watase ,  Shiro Mishima

    发明人： Norio Kimura ,  You Ishii ,  Hozumi Yasuda ,  Koji Saito ,  Masako Watase ,  Shiro Mishima

    IPC分类号： B24B37/00 ,  B24B57/02 ,  B24B7/00

    CPC分类号： B24B37/04 ,  B24B57/02

    摘要： A polishing apparatus for polishing a surface of an object such as a semiconductor wafer includes a turntable having a polishing cloth mounted on an upper surface thereof, a top ring for holding and pressing the object against the polishing cloth, and a plurality of radially arranged nozzles for supplying a polishing solution, containing abrasive material, of different concentrations that differ along a radial direction of the polishing cloth.

    摘要翻译： 用于研磨诸如半导体晶片的物体的表面的抛光装置包括具有安装在其上表面上的抛光布的转盘，用于将物体保持并按压在抛光布上的顶环，以及多个径向布置的喷嘴 用于供应不同浓度的研磨材料的抛光溶液，该研磨材料沿抛光布的径向方向不同。

    Beer filtering device
    32.
    发明授权
    Beer filtering device 失效
    啤酒过滤装置

    公开(公告)号：US5362387A

    公开(公告)日：1994-11-08

    申请号：US130431

    申请日：1993-10-01

    申请人： Koji Saito ,  Tetsuhisa Makino

    发明人： Koji Saito ,  Tetsuhisa Makino

    IPC分类号： B01D25/00 ,  B01D25/32

    CPC分类号： B01D25/003 ,  B01D2201/34

    摘要： A beer filtering device of a filter press type for filtering a beer stock. The beer filter device includes a plurality of filter plates (4) and a plurality of filter frames (6) arranged side by side in alternate relationship to each other. A filter element (28) is supported to each filter plate (4). A stock line (66) for supplying a beer stock and a filtrate line (68) for discharging a filtrate of the beer stock are so formed as to penetrate through the filter plates and the filter frames in the thickness direction thereof. The stock line and the filtrate line are sealed by a plurality of stock line seals (48) and a plurality of filtrate line seals (74), respectively, each interposed between the filter plate and the filter frame adjacent to each other in a filtering step. A plurality of washer liquid seals (76) are provided outside the stock line seals and the filtrate line seals in such a manner that each washer liquid seal is interposed between the filter plate and the filter frame adjacent to each other. In a washing step, a space defined by the filter plates and the filter frames is sealed by the washer liquid seals under the condition where the sealed condition of the stock line and the filtrate line by the stock line seals and the filtrate line seals is released. In this condition, a washer liquid is circulated in the sealed space defined by the washer liquid seals to thereby extensively wash and sterilize the interior of the beer filtering device.

    摘要翻译： 用于过滤啤酒原料的压滤机类型的啤酒过滤装置。 啤酒过滤装置包括多个过滤板（4）和多个彼此交替排列并排布置的过滤器框架（6）。 过滤元件（28）被支撑到每个过滤板（4）。 用于供应啤酒原料的库存管线（66）和用于排出啤酒原料滤液的滤液管线（68）形成为在其厚度方向上穿过过滤板和过滤器框架。 库存管线和滤液管线分别通过过滤步骤中彼此相邻的多个存储管线密封件（48）和多个滤液管线密封件（74）密封，所述多个滤液管线密封件（74）分别插入在过滤板和过滤器框架之间 。 多个洗涤液体密封件（76）设置在库存管线密封件外部和滤液线密封件处，使得每个清洗液体密封件插入在过滤板和彼此相邻的过滤器框架之间。 在洗涤步骤中，由过滤板和过滤器框架限定的空间在由库存管路密封条和滤液管线密封件的库存管线和滤液管线的密封条件和滤液管线密封件被释放的条件下被垫圈液体密封件密封 。 在这种情况下，洗涤液在由洗涤液密封件限定的密封空间内循环，从而对啤酒过滤装置的内部进行大量的洗涤和消毒。

    Process for producing taxol by cell culture of taxus species
    33.
    发明授权
    Process for producing taxol by cell culture of taxus species 失效
    通过紫杉属细胞培养生产紫杉醇的方法

    公开(公告)号：US5312740A

    公开(公告)日：1994-05-17

    申请号：US934512

    申请日：1992-10-09

    申请人： Koji Saito ,  Hiroaki Ohashi ,  Masaaki Hibi ,  Makoto Tahara

    发明人： Koji Saito ,  Hiroaki Ohashi ,  Masaaki Hibi ,  Makoto Tahara

    IPC分类号： C12N5/04 ,  C12P17/02 ,  C12N5/00 ,  C12N5/02 ,  C12P1/00

    CPC分类号： C12N5/04 ,  C12P17/02

    摘要： A callus and suspension culture cells containing taxol as an effective component, and a process for producing taxol therefrom, are provided. The callus and suspension culture cells containing taxol in a high content can be induced and proliferated by culturing a tissue of a plant belonging to the genus Taxus, particularly its female gametophyte. The process for cell culture is advantageously carried out in the presence of a particular combination of plant growth regulators known per se in a growth medium. A callus or suspension culture cells containing at least taxol as an effective component can be stably provided, making it possible to effectively produce taxol.

    摘要翻译： PCT No.PCT / JP92 / 00132 Sec。 371日期：1992年10月9日 102（e）日期1992年10月9日PCT提交1992年2月10日PCT公布。 第WO92 / 13961号公报 日期：1992年8月20日。提供含有紫杉醇作为有效成分的愈伤组织和悬浮培养细胞及其生产紫杉醇的方法。 含有高含量的紫杉醇的愈伤组织和悬浮培养细胞可以通过培养属于紫杉属的植物的组织，特别是其雌配子体而被诱导和增殖。 细胞培养的方法有利地在生长培养基中本身已知的植物生长调节剂的特定组合的存在下进行。 可以稳定地提供至少含有紫杉醇作为有效成分的愈伤组织或悬浮培养细胞，能够有效地生成紫杉醇。

    Proteinaceous substance showing antitumorous action and its preparing method
    34.
    发明授权
    Proteinaceous substance showing antitumorous action and its preparing method 失效
    显示抗肿瘤作用的蛋白质物质及其制备方法

    公开(公告)号：US4777241A

    公开(公告)日：1988-10-11

    申请号：US885737

    申请日：1986-07-21

    申请人： Tsutomu Irikura ,  Koichi Takagi ,  Jiro Hosomi ,  Satoshi Murayama ,  Koji Saito ,  Takashi Okazaki

    发明人： Tsutomu Irikura ,  Koichi Takagi ,  Jiro Hosomi ,  Satoshi Murayama ,  Koji Saito ,  Takashi Okazaki

    IPC分类号： G01N33/574 ,  A61K35/12 ,  A61K38/00 ,  A61K39/395 ,  A61P35/00 ,  C07K1/22 ,  C07K14/005 ,  C07K14/195 ,  C07K14/52 ,  C07K14/525 ,  C07K16/24 ,  C07K15/00

    CPC分类号： C07K14/52 ,  C07K16/24 ,  A61K38/00 ,  Y10S530/825 ,  Y10S930/144

    摘要： A proteinaceous substance having the following biochemical characteristics:(A) a strong cytolytic activity against mouse tumor cells L-929, but not cytotoxic activity for normal cells such as human fetus fibroblasts, human adult skin fibroblasts and chinese hamster fibroblasts (Don, V-79) and therefore a high tumor specificity: and(B) a strong anti-tumor and immunogenic activity against Meth-A sarcoma. When said substance is injected intravenously to the syngenic BALB/C mice inoculated with Meth-A sarcoma at a quantity of more than 72 units head, not only hemorrhagic necrosis, but also complete degradation is observed. Thereafter, even if it is attempted again to transplant the Meth-A sarcoma cells under the skin of Mice cured completely, successful plantation is not observed because of an acquired immunity:(C) the substance has no pyrogenetic action after intravenous injection to rabbits:(D) a molecular weight of 45,000.+-.5,000 (determined by the gel filtration method with Sephacryl S-200): and(E) an isoelectric point pI of 4.8+0.3: and a method for its manufacture.

    摘要翻译： 具有以下生物化学特性的蛋白质物质：（A）对小鼠肿瘤细胞L-929具有强的细胞溶解活性，但对于正常细胞如人胎儿成纤维细胞，人成年皮肤成纤维细胞和中国仓鼠成纤维细胞（Don，V- 79），因此具有高肿瘤特异性：（B）对Meth-A肉瘤的强抗肿瘤和免疫原性活性。 当将所述物质静脉内注射到以超过72单位头的量接种Meth-A肉瘤的同种BALB / C小鼠时，不仅出现出血性坏死，而且观察到完全降解。 此后，即使再次尝试将Meth-A肉瘤细胞移植到完全治愈的小鼠皮肤下，由于获得性免疫力，没有观察到成功的种植园：（C）静脉内注射兔子后物质没有致热作用： （D）分子量为45,000 +/- 5,000（通过使用Sephacryl S-200的凝胶过滤法测定）和（E）4.8±0.3的等电点pI及其制造方法。

    Device for fastening a belt or the like
    36.
    发明授权
    Device for fastening a belt or the like 失效
    用于固定皮带或类似物的装置

    公开(公告)号：US4564983A

    公开(公告)日：1986-01-21

    申请号：US576946

    申请日：1984-02-03

    申请人： Koji Saito

    发明人： Koji Saito

    IPC分类号： A44B11/12 ,  A44B19/00

    CPC分类号： A44B11/12 ,  Y10T24/4016 ,  Y10T24/4072

    摘要： A device for fastening a belt or the like, which comprises a first and a second component member. The first component member comprises a base plate, a pair of upstanding side walls and a cross rod having its opposite ends connected to the top ends of the side walls so that the base plate, the side walls and the cross rod form a frame defining a passage through which the belt or the like is to be passed. A bearing recess is formed in the inner surface of each of the side walls. The second component member comprises a body portion and a fastening portion extending angularly from one end of the body portion. The body portion is provided at the one end with a pair of pintles axially aligned and laterally outwardly projecting in opposite directions from the opposite lateral sides of the body portion and in the upper surface thereof with a bearing groove extending adjacent the one end of the body portion and in parallel with the common axis of the aligned pintles. The body portion is further provided at the opposite end with a slot for the belt to be attached to the second component member. The first and second component members are assembled with each of the pintles being engaged in one of the bearing recesses and the cross rod being engaged in the bearing groove so that the second component member is pivotable about the cross rod of the first component member.

    摘要翻译： 一种用于紧固带等的装置，其包括第一和第二构件。 第一构件包括基板，一对直立侧壁和横杆，其相对端连接到侧壁的顶端，使得底板，侧壁和横杆形成限定一个 通过皮带或类似物通过的通道。 在每个侧壁的内表面中形成有轴承凹部。 第二构件构件包括主体部分和从本体部分的一端成角度地延伸的紧固部分。 主体部分在一端设置有一对枢轴，其从主体部分的相对横向侧面沿相反方向轴向对齐并横向向外突出，并且在其上表面中具有与主体的一端相邻延伸的支承槽 并且与对准的枢轴的公共轴线平行。 主体部分在另一端处进一步设置有用于带附接到第二构件构件的槽。 第一和第二构件被组装成每个枢轴接合在一个轴承凹槽中，并且横杆接合在轴承槽中，使得第二构件可围绕第一构件的横杆枢转。

    Culture device, culture method and cultured organ produced by the culture method
    37.
    发明授权
    Culture device, culture method and cultured organ produced by the culture method 有权

    公开(公告)号：US11306281B2

    公开(公告)日：2022-04-19

    申请号：US16302728

    申请日：2016-05-19

    申请人： Koji Saito

    发明人： Koji Saito

    IPC分类号： C12M3/00 ,  C12M1/00 ,  C12M1/26 ,  C12N5/00

    摘要： A culture device and a culture method by which a substance to be cultured can be three-dimensionally cultured, and the substance thus cultured can be removed as an integrated product with multiple tubes; and a cultured organ produced by the culture method. The culture device comprises a sealed container (2) which contains the substance to be cultured (A) and is disassembled after the culture is completed; multiple ducts (3, 4, 5) arranged in the sealed container (2) and having a plurality of micropores formed on the outer peripheral surface; a culture medium-feeding device (6, 7) for feeding/circulating the culture medium (B) to at least one duct (3 or 5); an excretory device (8) connected to at least one duct (4) for excreting the waste product (C)permeating into the duct (4) through the micropores of the duct (4) from the substance to be cultured to the outside of the sealed container.