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公开(公告)号：US20080138383A1
公开(公告)日：2008-06-12
申请号：US11950989
申请日：2007-12-05
IPC分类号： A61K31/5513 , A61K31/4164 , A61K9/00 , A61P25/08 , A61K31/505
CPC分类号： A61K31/4164 , A61K9/0043 , A61K9/006 , A61K9/06 , A61K31/505 , A61K31/5513 , A61K47/10 , A61K47/36 , A61K47/38
摘要： This invention relates generally to pharmaceutical compositions for treating seizures, and, more particularly, to pharmaceutical compositions that are bioadherent to oral and/or nasal mucosa, comprise one or more anti-acute seizure agents, and can be used to treat one or more conditions selected from the group consisting of acute seizure, repetitive seizures, and status epilepticus. This invention also relates generally to methods for preparing such compositions, methods of treatment using such compositions, uses of such compositions to prepare medicaments, and kits comprising such compositions.
摘要翻译： 本发明一般涉及用于治疗癫痫发作的药物组合物，更具体地说，涉及对口腔和/或鼻粘膜具有生物粘附性的药物组合物，包含一种或多种抗急性发作剂，并且可用于治疗一种或多种病症 选自急性发作，重复性癫痫发作和癫痫持续状态组。 本发明一般还涉及制备这种组合物的方法，使用这种组合物的治疗方法，这种组合物的用途来制备药物，以及包含这些组合物的试剂盒。
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公开(公告)号：US06576666B2
公开(公告)日：2003-06-10
申请号：US09885158
申请日：2001-06-21
IPC分类号： A61K3120
CPC分类号： A23L33/12 , A23L33/10 , A23V2002/00 , Y10S514/87 , A23V2250/1872 , A23V2250/1874 , A23V2250/1882 , A23V2250/70 , A23V2250/156 , A23V2250/51084 , A23V2250/5118 , A23V2250/51088 , A23V2250/612 , A23V2250/1592
摘要： The present disclosure relates to novel nutritional compositions containing linoleic acid and/or linolenic acid which optimize child neurological development and provide improved nutritional support for women prior to and during lactation. The nutritional compositions are intended for use by women to optimize infant neurological development and provide improved nutritional support for women prior to, during and after lactation.
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公开(公告)号：US4471538A
公开(公告)日：1984-09-18
申请号：US388549
申请日：1982-06-15
申请人： Mark L. Pomeranz , R. Saul Levinson
发明人： Mark L. Pomeranz , R. Saul Levinson
CPC分类号： F16F9/30 , A43B13/189 , Y10S5/909
摘要： Shock absorbing devices utilize rheopexic fluid contained in a deformable sealed chamber which is subjected to external shock forces. Upon application of the shock forces to the deformable sealed chamber, the rheopexic fluid filled therein is exerted with shear stress which causes the rheopexic fluid to increase its consistency and shock absorbent characteristics as a function of increasing shear stresses applied thereto. Additionally, when used in an application wherein the device is placed against a body part of a user, the rheopexic material "molds" itself to the body portion of the user. When left at rest, the rheopexic material returns to its initial fluid, low-consistency state.
摘要翻译： 冲击吸收装置利用容纳在受到外部冲击力的可变形密封室中的流体流体。 当将冲击力施加到可变形的密封室时，填充在其中的流体流体施加剪切应力，这导致流变流体随着施加到其上的剪切应力的增加而增加其一致性和冲击吸收特性。 此外，当将该装置用于抵抗使用者的身体部位的应用中时，该流变材料将其本身“模制”到使用者的身体部位。 当静止时，流变材料返回其初始流体，低稠度状态。
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公开(公告)号：US09789057B2
公开(公告)日：2017-10-17
申请号：US13555472
申请日：2012-07-23
IPC分类号： A61K9/00
CPC分类号： A61K9/0036 , A61K9/0034
摘要： A pharmaceutical formulation to treat vaginal conditions in a human patient comprises: at least one active agent; a modified release dosage form which provides extended release of the anti-infective agent upon vaginal administration to the patient; and wherein the formulation, when containing a total dose of the anti-infective agent of about 25 μg to about 500 mg based on the active agent will produce a plasma concentration versus time curve (ng/mL versus hours) having an area under the curve (AUC) of less than about 600 ng/mL·hr.
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35.发明申请公开(公告)号：US20080193531A1
公开(公告)日：2008-08-14
申请号：US12027538
申请日：2008-02-07
CPC分类号： A61K45/06 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K31/56 , A61K33/06 , A61K33/18 , A61K33/24 , A61K33/26 , A61K33/30 , A61K33/34 , A61K33/42 , A61K2300/00
摘要： The present invention provides pharmaceutical compositions and methods for improving the absorption of nutrients and/or drugs in the gastrointestinal tract of a subject. Typically, the pharmaceutical compositions comprise a first agent that increases the pH of the stomach, and one or more agents selected from a pH lowering agent, a vitamin, a mineral, and a drug.
摘要翻译： 本发明提供用于改善受试者胃肠道中营养物质和/或药物吸收的药物组合物和方法。 通常，药物组合物包含增加胃的pH的第一药剂和选自pH降低剂，维生素，矿物质和药物的一种或多种药物。
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公开(公告)号：US20080161376A1
公开(公告)日：2008-07-03
申请号：US11954731
申请日：2007-12-12
IPC分类号： A61K31/4164 , A61P31/10
CPC分类号： A61K31/01 , A61K9/0014 , A61K31/22 , A61K31/4178 , A61K45/06 , A61K47/44
摘要： The present invention relates to methods of treatment of vulvovaginitis caused by nonspecified Candida isolates using controlled release antimycotic delivery systems. The invention utilizes a minimal number of administrations to obtain cessation of the condition. The methods and systems are especially effective against any Candida species causing vaginal irritation, and thus reduce the need for identification of the isolate prior to treatment.
摘要翻译： 本发明涉及使用控制释放的抗真菌递送系统治疗由非特异性假丝酵母属分离物引起的外阴阴道炎的方法。 本发明利用最少数量的施用来获得条件的停止。 所述方法和系统对于引起阴道刺激的任何念珠菌属物种特别有效，因此减少了在治疗前鉴定分离物的需要。
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公开(公告)号：US20070264329A1
公开(公告)日：2007-11-15
申请号：US11746832
申请日：2007-05-10
CPC分类号： A61K9/2059 , A23L29/015 , A23L33/16 , A23P10/25 , A23V2002/00 , A61K9/16 , A61K9/2027 , A61K33/10 , Y10S514/96 , A23V2250/1578 , A23V2250/7106
摘要： Compositions comprising calcium carbonate and processes for making such compositions are provided. The invention provides a granulation comprising about 95% to about 99% by weight calcium carbonate, about 0.5% to about 5% by weight of a binder and about 0.03% to about 3% by weight of a porosity increasing agent. A pharmaceutical or nutritional composition prepared from such a granulation comprises about 90% to about 99% by weight calcium carbonate, about 0.03% to about 3% by weight of a porosity increasing agent, and about 1% to about 10% by weight of other excipients. The composition provides a smaller tablet than conventional calcium carbonate compositions, for improved ease of swallowing.
摘要翻译： 提供了包含碳酸钙的组合物及其制备方法。 本发明提供了一种颗粒，其包含约95重量％至约99重量％的碳酸钙，约0.5重量％至约5重量％的粘合剂和约0.03重量％至约3重量％的孔隙率增加剂。 由这种造粒制备的药物或营养组合物包含约90％至约99％重量的碳酸钙，约0.03％至约3％重量的孔隙率增加剂和约1％至约10％重量的其它 赋形剂。 组合物提供比常规碳酸钙组合物更小的片剂，以改善容易吞咽。
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公开(公告)号：US06488956B1
公开(公告)日：2002-12-03
申请号：US09448744
申请日：1999-11-24
IPC分类号： A61K4700
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , A61K2300/00 , A23V2250/71 , A23V2250/211 , A23V2250/704 , A23V2250/712 , A23V2250/708 , A23V2250/702 , A23V2250/705 , A23V2250/1578 , A23V2250/1592 , A23V2250/1642 , A23V2250/1608 , A23V2250/1586 , A23V2250/16 , A23V2250/1588 , A23V2250/156 , A23V2250/70
摘要： Multi-vitamin and mineral supplements for administration to non-lactating women, which comprise specific regimens of vitamins and minerals tailored to meet the physiological needs of said women. Methods for optimizing the health of women by providing multi-vitamin and mineral supplements which are specifically tailored to achieve optimal regulation of growth, maintenance and repair of body tissue during specific stages of life with minimal side effects. Methods for formulating a multi-vitamin and mineral supplement that optimize the health of a woman and which comprise identifying life stages which correlate to specific nutritional requirements as a result of varying physiological conditions during a lifetime and selecting specific types and optimal amounts of vitamins and minerals for said life stages.
摘要翻译： 多种维生素和矿物质补充剂用于非哺乳妇女的管理，其中包括针对所述妇女的生理需要量身定制的维生素和矿物质的具体方案。 通过提供多种维生素和矿物质补充剂来优化妇女健康的方法，这些补充剂专门用于在生命的特定阶段实现人体组织的生长，维持和修复的最佳调节，并具有最小的副作用。 制备多种维生素和矿物质补充剂的方法，其优化女性的健康，其包括鉴定生命周期中与不同生理条件相关的特定营养需求的生命阶段，并选择特定类型和最佳量的维生素和矿物质 对于生命阶段
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公开(公告)号：US5869084A
公开(公告)日：1999-02-09
申请号：US474071
申请日：1995-06-07
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , Y10S514/905
摘要： Multi-vitamin and mineral supplements for administration to lactating, non-lactating, and menopausal women, which comprise specific regimens of critical nutritional agents. The supplements are specifically tailored to meet nutritional requirements and maintain a woman's health during each stage of life.
摘要翻译： 用于哺乳期，非哺乳期和绝经期妇女的多种维生素和矿物质补充剂，其包括关键营养剂的特定方案。 补品是专门为满足营养需求量身定制，并在生命的每个阶段保持女性的健康。
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公开(公告)号：US5730997A
公开(公告)日：1998-03-24
申请号：US712436
申请日：1996-09-11
CPC分类号： A61K9/0095 , Y10S514/849 , Y10S514/85 , Y10S514/974
摘要： A substantially tasteless liquid phramaceutical delivery system containing an active material and a high osmolarity aqueous system comprising (i) water; (ii) about 20% to about 45% by weight sugar derivative; (iii) about 10% to about 15% by weight hydrogenated maltose syrup; and (iv) about 0% to about 35% by weight polyhydroxy alcohol.
摘要翻译： 一种基本上无味的液体药物递送系统，其含有活性物质和高摩尔渗透浓度水系统，其包含（i）水; （ii）约20％至约45％重量的糖衍生物; （iii）约10重量％至约15重量％氢化麦芽糖浆; 和（iv）约0％至约35％重量的多羟基醇。
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