Device for isolation and/or purification of biomolecules

    公开(公告)号:US10514330B2

    公开(公告)日:2019-12-24

    申请号:US13809563

    申请日:2011-07-13

    IPC分类号: G01N1/40

    摘要: The present invention refers to a device, comprising a hollow body having at least one open end comprising at least one solid matrix binding, adsorbing, absorbing, chelating or retaining compounds which are not desired in a sample and preferably at least one barrier which is non-permeable for liquids and solids under ambience conditions, however, becomes liquid-permeable by applying an external force to the barrier, the use of such a device for isolating or purifying a biomolecule from a sample, a method for preparation of the device and a method for isolation or purification of any biomolecule using said device.

    Hydraulic cylinder for a hydraulic drawing cushion
    32.
    发明授权
    Hydraulic cylinder for a hydraulic drawing cushion 有权
    液压油缸用于液压绘图垫

    公开(公告)号:US09038431B2

    公开(公告)日:2015-05-26

    申请号:US13068054

    申请日:2011-04-29

    摘要: The invention resides in a hydraulic cylinder (23) for a hydraulic drawing cushion (20) of a drawing press (10). The hydraulic cylinder (23) includes a first operating chamber (47), a second operating chamber (48), and a third operating chamber (53). An annular piston (45) with a first piston surface area (49) and a second piston surface area (50) separates the first operating chamber (47) from the second operating chamber (48). The first and the second piston surfaces (49, 50) have the same size. A front surface of the piston rod (33) forms a third piston surface (54) which is larger than the first and second piston surfaces. The third piston surface (54) delimits the third operating chamber (53) of the hydraulic cylinder (23). The first and the second operating chambers (47, 48) are provided for controlling the position and/or the movement of the piston rod (33). The third operating chamber (53) serves to control the metal sheet clamping force of the drawing press via the piston rod (33).

    摘要翻译: 本发明涉及一种用于拉伸压机(10)的液压牵引垫(20)的液压缸(23)。 液压缸(23)包括第一操作室(47),第二操作室(48)和第三操作室(53)。 具有第一活塞表面区域(49)和第二活塞表面区域(50)的环形活塞(45)将第一操作室(47)与第二操作室(48)分开。 第一和第二活塞表面(49,50)具有相同的尺寸。 活塞杆(33)的前表面形成比第一和第二活塞表面大的第三活塞表面(54)。 第三活塞表面(54)限定液压缸(23)的第三操作室(53)。 第一和第二操作室(47,48)被设置用于控制活塞杆(33)的位置和/或运动。 第三操作室(53)用于经由活塞杆(33)来控制拉拔压力机的金属板夹紧力。

    Turbine housing for an exhaust gas turbocharger and method for producing turbine housing
    33.
    发明授权
    Turbine housing for an exhaust gas turbocharger and method for producing turbine housing 有权
    用于废气涡轮增压器的涡轮机壳体和用于制造涡轮机壳体的方法

    公开(公告)号:US08951007B2

    公开(公告)日:2015-02-10

    申请号:US13136540

    申请日:2011-08-03

    IPC分类号: F01D25/28 F01D25/24

    摘要: In the turbine housing for an exhaust gas turbocharger of a drive assembly at least one spiral channel, which can be coupled to an exhaust gas line of the drive assembly is provided A receiving chamber for a turbine wheel to which exhaust gas can be supplied is disposed upstream of the at least one spiral channel. The turbine wheel is disposed in the turbine housing so as to be rotatable about a rotational axis. A guide baffle is arranged fixed to the turbine housing in a transition region between the at least one spiral channel, the guide baffle being connected to the turbine housing by a metal-to-metal joint whereby the guide baffle is connected to the turbine housing in a particular tight manner.

    摘要翻译: 在用于驱动组件的废气涡轮增压器的涡轮机壳体中,至少一个可连接到驱动组件的排气管线的螺旋通道设置有用于可供给废气的涡轮机叶轮的容纳室, 在至少一个螺旋通道的上游。 涡轮机叶轮设置在涡轮机壳体中,以能够围绕旋转轴线旋转。 引导挡板在至少一个螺旋通道之间的过渡区域中固定到涡轮机壳体上,导向挡板通过金属对金属接头连接到涡轮机壳体,由此导向挡板连接到涡轮机壳体 一个特别紧张的方式。

    Film-shaped preparation comprising oily substances for oral administration
    34.
    发明授权
    Film-shaped preparation comprising oily substances for oral administration 有权
    包含用于口服给药的油性物质的膜状制剂

    公开(公告)号:US08758803B2

    公开(公告)日:2014-06-24

    申请号:US12736521

    申请日:2009-04-30

    CPC分类号: A61K9/0056 A61K9/7007

    摘要: Water-soluble, solid, film-shaped preparations comprising at least one film-forming polymer selected from the group consisting of the fully and partially hydrolyzed polyvinyl alcohols, and at least one water-insoluble, oily liquid which is incorporated into the film-forming polymer and amounts to at least 30 percent by weight, relative to the dry portion of the preparation. Methods for producing the preparations and the use thereof are also provided.

    摘要翻译: 包含至少一种选自全部和部分水解的聚乙烯醇的成膜聚合物的水溶性固体膜形制剂和至少一种不溶于水的油状液体,其被引入成膜剂 相对于制剂的干燥部分,其量为至少30重量%。 还提供了制备方法及其用途。

    DEVICE FOR ISOLATION AND/OR PURIFICATION OF BIOMOLECULES
    36.
    发明申请
    DEVICE FOR ISOLATION AND/OR PURIFICATION OF BIOMOLECULES 审中-公开
    用于分离和/或纯化生物分子的装置

    公开(公告)号:US20130115693A1

    公开(公告)日:2013-05-09

    申请号:US13809563

    申请日:2011-07-13

    IPC分类号: C12M3/00 C12N15/85

    CPC分类号: G01N1/4005

    摘要: The present invention refers to a device, comprising a hollow body having at least one open end comprising at least one solid matrix binding, adsorbing, absorbing, chelating or retaining compounds which are not desired in a sample and preferably at least one barrier which is non-permeable for liquids and solids under ambience conditions, however, becomes liquid-permeable by applying an external force to said barrier, the use of such a device for isolating or purifying a biomolecule from a sample, a method for preparation of said device and a method for isolation or purification of any biomolecule using said device.

    摘要翻译: 本发明涉及一种装置,其包括中空体,该中空体具有至少一个开放端,该至少一个开放端包含至少一个固体基质结合,吸附,吸收,螯合或保留在样品中不需要的化合物,优选至少一个不是 然而,在环境条件下对于液体和固体是不透气的,通过向所述阻挡层施加外力,使用这种用于从样品中分离或纯化生物分子的装置,所述装置的制备方法和 使用所述装置分离或纯化任何生物分子的方法。

    COMPONENT MANIPULATOR FOR THE DYNAMIC POSITIONING OF A SUBSTRATE, COATING METHOD, AS WELL AS USE OF A COMPONENT MANIPULATOR
    37.
    发明申请
    COMPONENT MANIPULATOR FOR THE DYNAMIC POSITIONING OF A SUBSTRATE, COATING METHOD, AS WELL AS USE OF A COMPONENT MANIPULATOR 审中-公开
    用于基板的动态定位的组件操纵器,涂层方法,如同使用组件操纵器

    公开(公告)号:US20130071575A1

    公开(公告)日:2013-03-21

    申请号:US13419770

    申请日:2012-03-14

    申请人: Markus Müller

    发明人: Markus Müller

    IPC分类号: B65G49/00

    摘要: The invention relates to a component manipulator for the dynamic positioning of a substrate to be treated in a thermal treatment process, wherein the component manipulator includes a main drive axle rotatable about a main rotary axis, a connection element and a substrate holder connectable to the connection element. In accordance with the invention the connection element is a ceramic connection element and a connection segment of the substrate holder is connectable to the connection element in a pull resistant and rotationally fixed manner by means of a plug and rotate connection with regard to a connection axis (V) of the plug and rotate connection and the substrate holder (5) is arranged rotatable about the connection axis (V). The invention further relates to a coating method, to a coating apparatus, as well as to the use of a component manipulator.

    摘要翻译: 本发明涉及一种用于在热处理过程中动态定位待处理基板的部件操纵器,其中所述部件操纵器包括可围绕主旋转轴线旋转的主驱动轴,连接元件和可连接到所述连接件的基板保持器 元件。 根据本发明,连接元件是陶瓷连接元件,并且衬底保持器的连接段可通过插头以抗拉和旋转固定的方式连接到连接元件,并且相对于连接轴线旋转连接 V),并且基板保持器(5)可绕连接轴线(V)旋转设置。 本发明还涉及涂覆方法,涂覆装置以及组件操纵器的使用。

    Airframe structure of an aircraft or spacecraft
    39.
    发明授权
    Airframe structure of an aircraft or spacecraft 有权
    飞机或航天器的机身结构

    公开(公告)号:US08016234B2

    公开(公告)日:2011-09-13

    申请号:US11891755

    申请日:2007-08-13

    IPC分类号: B64C1/00

    摘要: The present invention provides an airframe structure of an aircraft or spacecraft, with: a hollow body section which can be subjected to an internal pressure; a membrane arrangement which has at least one single-part, multi-curved membrane component for sealing off the internal pressure from an external pressure which acts on the hollow body section and differs from the internal pressure; and a joining structure for a pressure tight joining of the membrane arrangement to a region of the hollow body section; wherein the membrane arrangement forms a receiving well which is accessible from outside the hollow body section, extends at least partially into the hollow body section and is for receiving a component of the aircraft or spacecraft.

    摘要翻译: 本发明提供了一种飞机或航天器的机身结构,其具有:可承受内部压力的中空主体部分; 膜装置,其具有至少一个单一部分的多弯曲膜部件,用于将内部压力与作用在中空主体部分上并与内部压力不同的外部压力密封; 以及用于将所述膜装置压缩接合到所述中空主体部分的区域的接合结构; 其中所述膜装置形成从所述中空主体部分的外部可接近的接收井,至少部分延伸到所述中空主体部分中并且用于接收所述飞行器或航天器的部件。

    METHOD OF FABRICATING A TRANSISTOR WITH SEMICONDUCTOR GATE COMBINED LOCALLY WITH A METAL
    40.
    发明申请
    METHOD OF FABRICATING A TRANSISTOR WITH SEMICONDUCTOR GATE COMBINED LOCALLY WITH A METAL 有权
    制造半导体门与金属组合的晶体管的方法

    公开(公告)号:US20100102402A1

    公开(公告)日:2010-04-29

    申请号:US12521802

    申请日:2008-01-10

    摘要: A method of forming a field effect transistor comprising a gate formed on an insulating layer, the gate having, in a zone in contact with the insulating layer, a semiconducting central zone and lateral zones in the length of the gate, the method comprising forming a gate comprising a portion of insulating layer, a portion of semiconducting layer formed over the insulating layer, and a portion of mask layer formed over the semiconducting layer; performing an etching of the portion of the mask layer such that only a portion in the centre of the gate remains; and reacting the semiconducting gate with a metal deposited over the gate.

    摘要翻译: 一种形成场效应晶体管的方法,所述场效应晶体管包括形成在绝缘层上的栅极,所述栅极在与所述绝缘层接触的区域中具有在所述栅极长度上的半导体中心区域和侧向区域,所述方法包括形成 包括绝缘层的一部分的栅极,在绝缘层上形成的半导体层的一部分,以及形成在半导体层上的掩模层的一部分; 对所述掩模层的所述部分进行蚀刻,使得只有所述栅极的中心部分保留; 并使半导电栅极与沉积在栅极上的金属反应。