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公开(公告)号：US20100022911A1
公开(公告)日：2010-01-28
申请号：US12505926
申请日：2009-07-20
IPC分类号： A61B5/00
CPC分类号： A61B5/03 , A61B5/021 , A61B5/0537 , A61B5/4878
摘要： This document discusses, among other things, systems and methods for measuring the dynamics of pulmonary congestion in heart failure subjects over time to monitor the subjects susceptibility to pulmonary edema, including sensing and receiving information indicative of a bodily pressure and information indicative of pulmonary fluid, and using the transient responses of these measurements to compute parameters related to the dynamics of thoracic fluid accumulation, such as a critical pressure (Pc), a critical time (Tc), or a filtration index (Kfi).
摘要翻译： 本文件尤其讨论了随着时间的推移，测量心力衰竭受试者的肺充血动力学的系统和方法，以监测受试者对肺水肿的易感性，包括感测和接收指示身体压力的信息和指示肺动脉的信息， 并且使用这些测量的瞬态响应来计算与胸腔积液的动力学相关的参数，例如临界压力（Pc），临界时间（Tc）或过滤指数（Kfi）。
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公开(公告)号：US07138088B2
公开(公告)日：2006-11-21
申请号：US10121006
申请日：2002-04-10
CPC分类号： A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M5/16831 , A61M39/10 , G01N27/07 , G01N27/10 , G01N33/49
摘要： Apparatuses, devices, systems and methods for detecting access disconnection are provided. The present invention includes electrical contacts in fluid and electrical communication with a fluid passing between a patient and a medical system during therapy. In this regard, the present invention can use a direct-contact measurement to detect access disconnection, such as dislodgment of an access device from the patient through which fluid can flow during therapy including, for example, medication delivery, dialysis therapy and the like.
摘要翻译： 提供了用于检测接入断开的设备，设备，系统和方法。 本发明包括在治疗期间流体中通过患者和医疗系统之间的流体的电接触。 在这方面，本发明可以使用直接接触测量来检测接近断开，诸如在治疗期间流体可以通过其流动的患者的进入装置的移位，包括例如药物输送，透析治疗等。
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33.发明授权Monitoring projections along principal components of multiple sensors as an indicator of worsening heart failure 有权根据多个传感器的主要组件监测预测作为心力衰竭恶化的指标公开(公告)号：US08858448B2
公开(公告)日：2014-10-14
申请号：US13325120
申请日：2011-12-14
申请人： Pramodsingh Hirasingh Thakur , Abhilash Patangay , Ramesh Wariar , John D. Hatlestad , Yi Zhang
发明人： Pramodsingh Hirasingh Thakur , Abhilash Patangay , Ramesh Wariar , John D. Hatlestad , Yi Zhang
IPC分类号： A61B5/02 , A61B5/11 , A61B5/0205 , A61B5/042 , A61B5/00 , A61B7/02 , A61B5/08 , A61N1/362 , A61B7/04 , A61N1/37 , A61B5/053
CPC分类号： A61B5/042 , A61B5/0205 , A61B5/053 , A61B5/0809 , A61B5/1107 , A61B5/6869 , A61B5/7253 , A61B7/023 , A61B7/04 , A61B2562/0219 , A61N1/3627 , A61N1/37
摘要： A device can include at least a first physiologic sensor circuit configured to provide a first physiologic signal, a second physiologic sensor circuit configured to provide a second physiologic signal, and a processor circuit. The processor circuit includes a principal component analysis circuit configured to represent data determined from the at least first and second physiologic sensor circuits as at least first and second axes, respectively, in a multidimensional space, determine one or more principal components in the multidimensional space, determine a quantitative attribute of the first and the second physiologic signals using at least one of the determined principal components or a projection of the data along the at least one determined principal component, and provide an indication of heart failure status according to the quantitative attribute to at least one of a user or a process.
摘要翻译： 装置可以包括至少第一生理传感器电路，其被配置为提供第一生理信号，被配置为提供第二生理信号的第二生理传感器电路和处理器电路。 处理器电路包括主分量分析电路，其被配置为将表示从至少第一和第二生理传感器电路确定的数据分别表示为多维空间中的至少第一和第二轴，确定多维空间中的一个或多个主要分量， 使用确定的主成分中的至少一个或沿着至少一个确定的主成分的数据的投影来确定第一和第二生理信号的定量属性，并且根据定量属性提供心力衰竭状态的指示 至少一个用户或进程。
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34.发明授权Remote monitoring of patient cognitive function using implanted CRM devices and a patient management system 有权使用植入式CRM设备和患者管理系统远程监测患者认知功能公开(公告)号：US08337408B2
公开(公告)日：2012-12-25
申请号：US11457247
申请日：2006-07-13
申请人： Ramesh Wariar , Robert J. Sweeney
发明人： Ramesh Wariar , Robert J. Sweeney
IPC分类号： A61B5/02
CPC分类号： A61B5/16 , A61B5/0002 , A61B5/02028 , A61B5/7275 , G06F19/00
摘要： This document discusses, among other things, a system and method for remote monitoring of patient cognitive function using implanted cardiac rhythm management (CRM) devices and a patient management system. The method comprising: presenting a cognitive test to a patient via a user interface; receiving a result of the cognitive test using the user interface; and using the result of the cognitive test in determining a heart failure condition status.
摘要翻译： 本文件还讨论了使用植入式心律管理（CRM）设备和患者管理系统远程监测患者认知功能的系统和方法。 该方法包括：经由用户界面向患者呈现认知测试; 使用用户界面接收认知测试的结果; 并使用认知测试的结果来确定心力衰竭状态。
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公开(公告)号：US20120203092A1
公开(公告)日：2012-08-09
申请号：US13366473
申请日：2012-02-06
IPC分类号： A61B5/0408 , A61B5/02 , A61B5/00
CPC分类号： A61B5/4833 , A61B5/0002 , A61B5/0031 , A61B5/024 , A61B5/053 , A61B5/08 , A61B5/1118 , A61B5/6831 , A61B2560/0431 , A61N1/3627 , A61N1/36521 , A61N1/3702
摘要： Systems and methods to monitor an improvement of a subject's physiological condition using a goal improvement profile are described. In an example, a physiological condition of a subject can be compared to a goal improvement profile, where the profile includes at least one target condition indicative of an improved physiological condition detectable using a physiological sensor signal, and a target time when the subject is expected to reach the target condition, where the comparison can be used to indicate whether the subject has met the target condition by the target time.
摘要翻译： 描述使用目标改进简档来监测对象生理状况改善的系统和方法。 在一个实例中，可以将受试者的生理状况与目标改善曲线进行比较，其中轮廓包括指示使用生理传感器信号可检测到的改善的生理状态的至少一个目标条件以及预期受试者的目标时间 达到目标条件，其中可以使用比较来指示被摄体是否在目标时间内达到目标条件。
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公开(公告)号：US20110303590A1
公开(公告)日：2011-12-15
申请号：US13213707
申请日：2011-08-19
申请人： Robert W. Childers , David S. Brown , Ramesh Wariar , Sujatha Karoor , Shahid Din , Leo Martis , Cody Buchmann , Paul Soltys
发明人： Robert W. Childers , David S. Brown , Ramesh Wariar , Sujatha Karoor , Shahid Din , Leo Martis , Cody Buchmann , Paul Soltys
CPC分类号： A61M1/1696 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/28 , A61M1/284 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2202/0413 , A61M2205/12 , A61M2205/3306 , A61M2205/3327
摘要： A hemodialysis system including (i) a dialyzer; (ii) a blood circuit including a blood pump in fluid communication with the dialyzer; (iii) a dialysate circuit including a dialysate circulation pump in fluid communication with the dialyzer, the dialysate circuit further including a sorbent cartridge for cleaning used dialysate; (iv) a container holding an initial supply of dialysate; (v) a container pump in fluid communication with the dialysate circuit and the container; (vi) a supply of concentrate; and (vii) an electronic weight balance positioned and arranged to weigh the supply of concentrate.
摘要翻译： 一种血液透析系统，包括（i）透析器; （ii）包括与所述透析器流体连通的血液泵的血液回路; （iii）透析液回路，其包括与所述透析器流体连通的透析液循环泵，所述透析液回路还包括用于清洗使用过的透析液的吸附剂盒; （iv）容纳初始供应透析液的容器; （v）与透析液回路和容器流体连通的容器泵; （vi）精矿供应; 和（vii）定位和布置成对浓缩物供应进行称重的电子重量平衡。
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37.发明申请公开(公告)号：US20110237998A1
公开(公告)日：2011-09-29
申请号：US13157010
申请日：2011-06-09
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： An access disconnection method for a machine employing a blood circuit, the blood circuit having a machine segment and a patient access segment, the method comprising: injecting an electrical signal into the blood circuit between the machine segment and the patient access segment; attempting to cause the electrical signal to flow through only the patient access segment and to bypass the machine segment; and measuring the signal in the patient access segment and determining that an access disconnection event has occurred upon a threshold change in the measured signal.
摘要翻译： 一种采用血液循环的机器的接入断开方法，所述血液回路具有机器段和患者接入段，所述方法包括：将电信号注入所述机器段和所述患者接入段之间的血液回路中; 试图使电信号仅流过患者接入段并绕过机器段; 以及测量患者访问段中的信号，并且在测量信号的阈值改变时确定存在接入断开事件已经发生。
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公开(公告)号：US20100312130A1
公开(公告)日：2010-12-09
申请号：US12860152
申请日：2010-08-20
申请人： Yi Zhang , Kent Lee , Shibaji Shome , Qi An , Ramesh Wariar
发明人： Yi Zhang , Kent Lee , Shibaji Shome , Qi An , Ramesh Wariar
IPC分类号： A61B5/02
CPC分类号： A61B5/02 , A61B5/0402 , A61B5/0535 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36578 , A61N1/3702 , A61N1/37252
摘要： Severity and confidence level of a myocardial ischemia event can be determined, such as including using an ambulatory medical device, and such information can be used to determine a graded response to the myocardial ischemia event.
摘要翻译： 可以确定心肌缺血事件的严重性和置信水平，例如包括使用移动医疗装置，并且可以使用这些信息来确定对心肌缺血事件的分级响应。
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39.发明授权Urinalysis for the early detection of and recovery from worsening heart failure 失效尿液分析用于早期检测和恢复心力衰竭恶化公开(公告)号：US07606617B2
公开(公告)日：2009-10-20
申请号：US11343441
申请日：2006-01-31
申请人： Ramesh Wariar
发明人： Ramesh Wariar
IPC分类号： A61N1/00
CPC分类号： A61B5/002 , A61B5/0022 , A61B5/0809 , A61B5/145 , A61B5/14507 , A61B5/201 , A61B5/208 , A61B5/4878 , A61B10/007 , A61N1/3627 , G01N2800/325 , G06F19/00 , G16H40/67
摘要： A system and method of detecting decompensation of heart failure for a patient includes urinalysis to determine the change in physical and/or chemical composition of a patient's urine over time. The change in chemical and/or physical composition of the patient's urine is used to infer the onset of decompensation. Optionally, the inference is verified with other data, such as with baseline transthoracic impedance data, patient weight data, and/or blood composition data.
摘要翻译： 检测患者心力衰竭代偿失调的系统和方法包括尿分析以确定患者尿液随时间的物理和/或化学成分的变化。 使用患者尿液的化学和/或物理组成的变化来推断失代偿发作。 可选地，使用其他数据（例如具有基线经胸阻抗数据，患者体重数据和/或血液成分数据）验证推断。
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40.发明申请System And Method For Performing Remote Patient Risk Assessment Through A Visual Analog Scale 审中-公开通过视觉模拟量表进行远程患者风险评估的系统和方法公开(公告)号：US20090149719A1
公开(公告)日：2009-06-11
申请号：US12257296
申请日：2008-10-23
IPC分类号： A61B5/00
CPC分类号： A61B5/0002 , A61B5/022 , A61B5/0402 , A61B5/0476 , A61B5/0531 , A61B5/091 , A61B5/7275 , A61B5/7475 , G06F19/3418 , G16H10/20
摘要： A system and method for integrating qualitative assessment into remote patient management through a visual analog scale is provided. A query is associated to a physiological condition. A visual analog scale includes a linear gradient and, at each end, descriptors for a range of subjective and continuous responses to the query. Assessment data for a patient is obtained. A medical device of the patient is interrogated and stored data is received. The query is displayed with the visual analog scale. An answer to the query includes a point selected between the ends of and along the linear gradient. A distance of the point from one end of the linear gradient is determined. The distance is quantified as a fixed value in proportion to the distance. A risk to the patient is assessed. The stored data and the fixed value are analyzed against the physiological condition to represent patient wellness.
摘要翻译： 提供了一种通过视觉模拟量表将定性评估整合到远程患者管理中的系统和方法。 查询与生理条件相关联。 视觉模拟量表包括线性梯度，并且在每一端都有一系列对查询的主观和连续响应的描述符。 获得患者的评估数据。 询问患者的医疗装置并接收存储的数据。 查询以视觉模拟量表显示。 查询的答案包括在线性渐变的两端之间选择的点。 确定从线性梯度的一端的点的距离。 距离被量化为与距离成比例的固定值。 评估患者的风险。 根据生理条件分析存储的数据和固定值以表示患者健康。
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