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31.发明申请公开(公告)号：US20110026793A1
公开(公告)日：2011-02-03
申请号：US12673089
申请日：2008-05-30
IPC分类号： G06K9/48
CPC分类号： G06T7/13 , G06T7/155 , G06T7/37 , G06T7/60 , G06T17/30 , G06T2207/10072 , G06T2207/20041 , G06T2207/20044 , G06T2207/20048 , G06T2207/30021 , G06T2207/30028 , G06T2207/30101 , G06T2207/30172 , G06T2210/41 , G06T2211/404
摘要： A computer implemented method (350) for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure (360). a gradient field of a distance transformation is computed for the edge-detected dataset (380). a voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field (390).
摘要翻译： 描述了一种用于确定三维管状结构的中心线的计算机实现方法（350）。 该方法包括根据用于管状结构（360）的三维体素数据集提供表征管状结构的边界的体素的边缘检测数据集。 针对边缘检测数据集（380）计算距离变换的梯度场。 根据梯度场的导数计算对应于管状结构的中心线的体素数据集（390）。
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公开(公告)号：US07232459B2
公开(公告)日：2007-06-19
申请号：US10609835
申请日：2003-06-30
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/95 , A61F2002/075 , A61F2002/8483 , A61F2002/9517
摘要： A thoracic stent graft (20) has a tubular bio-compatible graft material body (22) with a lumen therethrough with a proximal end (26) and a distal end (27). There is a sealing stent (28) at the proximal end of the tubular body with an anchoring device which may be a barb (30) affixed to the sealing stent. A distal attachment stent (34) with barbs (36) can be affixed to and extend from the distal end (27) of the graft material body. Intermediate stents (24) are provided along the length of the body. The thoracic stent graft can be in one or two portions.
摘要翻译： 胸部支架移植物（20）具有管状的生物相容的移植材料体（22），其具有通过其穿过其的内腔具有近端（26）和远端（27）。 在管状体的近端处存在密封支架（28），其具有锚固装置，锚固装置可以是固定到密封支架上的倒钩（30）。 具有倒刺（36）的远侧附接支架（34）可以固定到移植物材料主体的远端（27）并从其延伸。 中心支架（24）沿身体的长度设置。 胸部支架移植物可以在一个或两个部分。
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公开(公告)号：US06749619B2
公开(公告)日：2004-06-15
申请号：US09989813
申请日：2001-11-20
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0076 , A61F2230/008 , A61F2230/0091 , A61F2230/0093 , A61M25/007
摘要： An apparatus (10) for eliminating dislodged thrombus (78) in a blood vessel (12) comprises a catheter (72) having a plurality of infusion ports (90) and a filter (76) attached to the catheter for trapping the dislodged thrombus carried by blood flow in the blood vessel. The infusion ports (90) are disposed within the filter (76) and are operable to deliver a thrombolytic fluid to dissolve the dislodged thrombus (78) trapped in the filter (76).
摘要翻译： 用于消除血管（12）中的脱出血栓（78）的装置（10）包括具有多个输注端口（90）的导管（72）和附接到导管的过滤器（76），用于捕获携带的移出的血栓 通过血管中的血流。 输液端口（90）设置在过滤器（76）内，并且可操作地输送血栓溶解流体以溶解被捕获在过滤器（76）中的脱出的血栓（78）。
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公开(公告)号：US09211183B2
公开(公告)日：2015-12-15
申请号：US13498492
申请日：2010-10-04
申请人： Krasnodar Ivancev , Michael Lawrence-Brown , David Ernest Hartley , Werner Dieter Ducke , Roy K. Greenberg
发明人： Krasnodar Ivancev , Michael Lawrence-Brown , David Ernest Hartley , Werner Dieter Ducke , Roy K. Greenberg
CPC分类号： A61F2/07 , A61F2/89 , A61F2/954 , A61F2002/061 , A61F2002/075 , A61F2210/0014 , A61F2230/0006 , A61F2230/0008
摘要： A stent graft (1) has at least one fenestration (13) or low profile side arm (34). A guide assembly (17) surrounds the fenestration or low profile side arm. The guide assembly has a continuous wall extending laterally away from the outer surface of the stent graft. The continuous wall is substantially elliptical or circular and extends distally of the fenestration at a distal end of the wall and being coincident with a proximal part (25) of the periphery of the fenestration or low profile side arm at a proximal end of the wall (23). The wall acts to define a guide area to guide a flexible probe extended from a side branch vessel to enter the fenestration or low profile side arm. Where there are two fenestrations or low profile side arms there can be a single continuous wall (50) around both or separate walls for each. The wall may have a peripheral wire reinforcement (19).
摘要翻译： 支架移植物（1）具有至少一个开窗（13）或低轮廓侧臂（34）。 引导组件（17）围绕开窗或薄型侧臂。 引导组件具有从支架移植物的外表面横向延伸的连续壁。 连续壁基本上是椭圆形或圆形的，并且在壁的远端处的开窗的远端延伸并且与壁的近端处的开窗或低轮廓侧臂的周边的近端部分（25）重合 23）。 壁用于限定引导区域，以引导从侧分支容器延伸的柔性探针进入开窗或低轮廓侧臂。 在有两个开窗或薄型侧臂的地方，每一个围绕两个或单独的墙壁都可以有一个单一的连续墙壁（50）。 壁可以具有外围钢丝加强件（19）。
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公开(公告)号：US09162073B2
公开(公告)日：2015-10-20
申请号：US12934930
申请日：2008-05-30
CPC分类号： A61N1/3787 , A61F2/26 , A61F2/82 , A61F2250/0001 , A61N1/0551 , A61N1/36007 , A61N1/3605 , A61N1/36107 , A61N1/37205
摘要： A method for treating erectile dysfunction in a subject includes providing an expandable support member for engaging a wall of a blood vessel. The expandable support member includes at least one electrode connected with the expandable support member and arranged to selectively deliver electric current to modulate the autonomic nervous system (ANS). The expandable support member includes and an insulative material attached to at least a portion of the expandable support member for isolating blood flowing through the vessel from the electric current delivered by the at least one electrode. The expandable support member is implanted intravascularly so that at least a portion of the expandable support member is positioned substantially adjacent a desired location where modulation of the ANS is effective to improve erectile function. After implanting the expandable support member, electric current is delivered to the at least one electrode to effect a change in the ANS.
摘要翻译： 用于治疗受试者勃起功能障碍的方法包括提供用于接合血管壁的可扩张支撑构件。 可扩展支撑构件包括至少一个电极，其与可扩张支撑构件连接并且被布置成选择性地输送电流以调制自主神经系统（ANS）。 可膨胀支撑构件包括附接到可膨胀支撑构件的至少一部分的绝缘材料，用于将流过容器的血液与由至少一个电极输送的电流隔离。 可膨胀支撑构件植入血管内，使得可扩展支撑构件的至少一部分基本上邻近于ANS的调节有效改善勃起功能的期望位置。 在植入可扩展支撑构件之后，将电流输送到至少一个电极以实现ANS的改变。
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公开(公告)号：US08845708B2
公开(公告)日：2014-09-30
申请号：US11600655
申请日：2006-11-16
CPC分类号： A61F2/954 , A61F2/07 , A61F2002/065
摘要： A stent graft introducer has a pusher, a nose cone, a region between the pusher and the nose cone for a stent graft, a sleeve extending over the pusher and proximally to the nose cone to cover the stent graft when retained in the region. An indwelling auxiliary catheter with a pre-curved proximal end is fitted into the introducer. The nose cone has an elongate groove and the auxiliary catheter has its proximal end in the elongate groove. In a partially retracted position of the sleeve the curved proximal end of the indwelling auxiliary catheter is exposed and uncovered by the sleeve and in an advanced position of the sleeve the curved proximal end of the indwelling auxiliary catheter is straightened, extends along the length of the groove in the nose cone and is covered by the sleeve.
摘要翻译： 支架移植物导引器具有推动器，鼻锥体，用于支架移植物的推动器和鼻锥体之间的区域，在保持在该区域中时延伸到推动器上并且向近端延伸到鼻锥体的套筒以覆盖支架移植物。 具有预弯曲近端的留置辅助导管安装在导引器中。 鼻锥具有细长的凹槽，辅助导管的近端位于细长凹槽中。 在套管的部分缩回位置，留置辅助导管的弯曲近端由套筒暴露和未覆盖，并且在套筒的前进位置中，留置辅助导管的弯曲近端被拉直，沿着 凹槽在鼻锥中并被套筒覆盖。
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公开(公告)号：US08140170B2
公开(公告)日：2012-03-20
申请号：US12101452
申请日：2008-04-11
IPC分类号： A61N1/05
CPC分类号： A61N1/36007 , A61N1/0558
摘要： An apparatus for renal neuromodulation includes an expandable support member having a main body portion for engaging a wall of a blood vessel proximate a renal vasculature and at least one electrode connected with the main body portion. The at least one electrode is arranged to selectively deliver electric current to a desired location where modulation of the sympathetic nervous system is effective to alter renal function. The apparatus further includes an insulative material attached to at least a portion of the main body portion for isolating blood flow through the vessel from the electric current delivered by the at least one electrode.
摘要翻译： 用于肾神经调节的装置包括可扩张支撑构件，其具有用于接合靠近肾血管系统的血管壁和与主体部分连接的至少一个电极的主体部分。 所述至少一个电极布置成选择性地将电流输送到期望的位置，其中交感神经系统的调节有效地改变肾功能。 该装置还包括附接到主体部分的至少一部分的绝缘材料，用于将通过该容器的血流与由至少一个电极传送的电流隔离。
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公开(公告)号：US20110270375A1
公开(公告)日：2011-11-03
申请号：US13181249
申请日：2011-07-12
IPC分类号： A61F2/84
CPC分类号： A61F2/954 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/958 , A61F2/962 , A61F2/966 , A61F2002/067 , A61F2002/9511 , A61F2002/9583 , A61F2002/9665
摘要： An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.
摘要翻译： 用于开窗或分枝的支架移植物（13）的引入装置，其用于展开到具有从其延伸的盲血管的血管的内腔中。 导引器（1）具有旨在在使用中保持在患者外部的远端和具有鼻锥形扩张器（11）的近端和用于将分支的支架移植物保持在鼻锥扩张器的远侧的布置。 引导器上的护套（15）在分支支架移植物上延伸到鼻锥扩张器。 留置导管（22）从引导器的远端延伸并进入开窗或侧臂并通过鼻锥扩张器，留置导管具有延伸通过其的导丝（29）。 引导线可以延伸到使用中的鼻锥扩张器之外，然后将护套从分支的支架移植物中取出，使得其可以从对侧动脉中截获。
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39.发明授权Apparatus and methods for repairing the function of a diseased valve and method for making same 有权用于修复患病阀的功能的装置和方法及其制造方法公开(公告)号：US07799072B2
公开(公告)日：2010-09-21
申请号：US11436521
申请日：2006-05-18
申请人： Roy K. Greenberg
发明人： Roy K. Greenberg
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2475 , A61F2/856 , A61F2220/0008 , A61F2220/0016 , A61F2220/0066 , A61F2230/0017
摘要： An apparatus for repairing the function of a diseased valve includes an annular first support member expandable to a first diameter. An annular second support member is spaced axially apart from the first support member and is expandable to a second diameter that is independent of the first diameter. A tubular graft section interconnects the first and second support members. The graft section defines an annulus having a third diameter that is independent of each of the first and second diameters. A prosthetic valve is secured within the annulus of the graft section. The bioprosthetic valve has at least two valve leaflets that are coaptable to permit the unidirectional flow of blood. Methods for repairing the function of a diseased valve and for making the apparatus are also provided.
摘要翻译： 用于修复患病阀的功能的装置包括可扩展到第一直径的环形第一支撑构件。 环形第二支撑构件与第一支撑构件轴向隔开并且可扩张到独立于第一直径的第二直径。 管状移植部分将第一和第二支撑构件相互连接。 移植部分限定具有独立于第一和第二直径中的每一个的第三直径的环带。 假体瓣膜固定在移植物部分的环空中。 生物假体瓣膜具有至少两个适合于允许血液单向流动的瓣膜小叶。 还提供了用于修复患病阀的功能和制造该装置的方法。
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公开(公告)号：US07776052B2
公开(公告)日：2010-08-17
申请号：US10003011
申请日：2001-11-01
IPC分类号： A61F11/00
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/22035 , A61B2017/22038 , A61B2017/2215 , A61B2090/08021 , A61F2/95
摘要： A medical grasping device (10) for vascular use, having an outer sheath (12), an elongate control member (50) extending within an outer sheath (12) to a distal tip section (54), and a proximal control assembly (22) including an actuation section (24) joined to the elongate control member (50). Adjacent to the distal tip section (54) is a grasping portion (70,70′) that is extendable from the outer sheath (12) to create loops (74,74′) for grasping a target object (T) for repositioning within the vascular system, or for removal from the patient, with loops being retractable into the outer sheath to hold the target object against the device (10) during movement of the device. Elongate control member (50) is preferably a cannula or tube having a lumen (58) extending completely therethrough for placement over a guide wire (28) already in the patient.
摘要翻译： 一种用于血管使用的医疗夹持装置（10），具有外护套（12），在外护套（12）内延伸到远侧末端部分（54））的细长控制构件（50）和近端控制组件 ）包括连接到细长控制构件（50）的致动部分（24）。 与远侧末端部分（54）相邻的是抓握部分（70,70'），其可从外部护套（12）延伸以产生用于抓握目标物体（T）的环（74,74'），用于重新定位 血管系统或用于从患者移除的环，其中环可缩回到外护套中，以在装置移动期间将目标物体抵靠装置（10）保持。 细长控制构件（50）优选地是具有完全延伸穿过其中的内腔（58）的插管或管，用于放置在已经在患者体内的引导线（28）上。
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