公开(公告)号：US08901312B2

公开(公告)日：2014-12-02

申请号：US13634263

申请日：2011-03-09

申请人： Takamitsu Hosoya ,  Isao Kii ,  Suguru Yoshida ,  Takeshi Matsushita

发明人： Takamitsu Hosoya ,  Isao Kii ,  Suguru Yoshida ,  Takeshi Matsushita

IPC分类号： C07D249/16 ,  C07D487/04

CPC分类号： C07D487/04 ,  C07D249/04 ,  C07K1/1077

摘要： The invention aims in establishing a method for modifying biomolecules using a reaction that efficiently modifies biomolecules and is widely applicable. The invention thus provides a cyclic compound containing two triazole rings formed by adding and ligating an azide compound possessing an azido group to each of the two carbon-carbon triple bond sites of an eight-membered cyclic skeleton of a cyclic diyne compound by a double click reaction; a method for producing a cyclic compound using a double click reaction; and a method for modifying biomolecules.

摘要翻译： 本发明旨在建立一种使用有效修饰生物分子的反应来修饰生物分子的方法，并且是广泛适用的。 因此，本发明提供一种环状化合物，其包含通过双键加成并连接具有叠氮基的叠氮化合物与环状二炔化合物的八元环骨架的两个碳 - 碳三键位点形成的两个三唑环 反应; 使用双键反应制备环状化合物的方法; 和一种修饰生物分子的方法。

公开(公告)号：US08545137B2

公开(公告)日：2013-10-01

申请号：US13377018

申请日：2011-03-03

申请人： Toshiharu Aiso ,  Kei Miyanishi ,  Suguru Yoshida

发明人： Toshiharu Aiso ,  Kei Miyanishi ,  Suguru Yoshida

IPC分类号： B23B51/06

CPC分类号： B23Q11/1046 ,  B23B35/00 ,  B23B2222/84 ,  B23B2250/12 ,  B23C2250/12 ,  C21D1/667 ,  C21D1/76 ,  C21D2261/00 ,  C22C38/001 ,  C22C38/002 ,  C22C38/02 ,  C22C38/04 ,  C22C38/06 ,  C22C38/60 ,  Y02P70/169 ,  Y10T83/0443 ,  Y10T408/03 ,  Y10T408/44 ,  Y10T408/45

摘要： The cutting method of steel for machine structural use includes: forming a mist by mixing a cutting fluid supplied at a supply rate of 0.01 ml/hour to 200 ml/hour and an oxidizing gas containing, by volume %, 21% to 50% of oxygen; and cutting the steel for machine structural use while the mist is blown on the cutting edge surface of a tool and the surface of the steel for machine structural use, wherein the steel for machine structural use includes, by mass %: C: 0.01% to 1.2%, Si: 0.005% to 3.0%, Mn: 0.05% to 3.0%, P: 0.001% to 0.2%, S: 0.001% to 0.35%, N: 0.002% to 0.035%, Al: 0.05% to 1.0%, and the balance consisting of Fe and inevitable impurities in which O is limited to 0.003% or less, and the amount of Al [Al %] and the amount of N [N %] satisfy [Al %]−(27/14)×[N %]≧0.05.

摘要翻译： 用于机械结构用途的钢的切割方法包括：通过将以0.01ml /小时的供给速度供给的切削液与200ml /小时的混合形成雾，以及以体积％计含有21％至50％的 氧; 并且在将工具的切削刃表面和机械结构用钢的表面喷雾时，切割用于机械结构的钢，其中，机械结构用钢为质量％：C：0.01％〜 1.2％，Si：0.005〜3.0％，Mn：0.05〜3.0％，P：0.001〜0.2％，S：0.001〜0.35％，N：0.002％〜0.035％，Al：0.05〜1.0％ ，余量由Fe和不可避免的杂质构成，其中O限制在0.003％以下，Al [Al％]和N [N％]的量满足[Al％] - （27/14） ×[N％]> = 0.05。

公开(公告)号：US20120232272A1

公开(公告)日：2012-09-13

申请号：US13412682

申请日：2012-03-06

申请人： Satoshi INOUYE ,  Yuiko Miura ,  Suguru Yoshida ,  Takamitsu Hosoya

发明人： Satoshi INOUYE ,  Yuiko Miura ,  Suguru Yoshida ,  Takamitsu Hosoya

IPC分类号： C07D487/04 ,  C07D241/38

CPC分类号： C07D241/38 ,  C07D241/20 ,  C07D241/44 ,  C07D241/54 ,  C07D487/04 ,  Y02P20/55

摘要： A simple process for producing v-coelenterazine compounds has been desired. Described is a process for producing a v-coelenterazine compound represented by general formula (II) comprising (1) the step of reacting a compound of general formula (VIII) with a methyltriphenylphosphonium salt in the presence of a base to give a compound represented by general formula (IX), (2) the step of performing a ring-closing metathesis reaction on any one selected from the group consisting of the compound represented by general formula (IX) and a compound of general formula (X) which is the compound of general formula (IX) wherein the amino is protected with R5, and then deprotecting R4 and, if any, R5 to give a v-coelenteramine compound represented by general formula (XIV), and (3) the step of reacting the compound of general formula (XIV) with a compound represented by general formula (XV) to give the compound of general formula (II).

摘要翻译： 已经需要制备v-肠溶纤维素化合物的简单方法。 本发明描述了一种制备由通式（II）表示的β-环糊精化合物的方法，包括（1）在碱存在下使通式（Ⅷ）化合物与甲基三苯基鏻盐反应，得到由 通式（IX），（2）对选自由通式（IX）表示的化合物和作为化合物的通式（X）的化合物的任何一种进行闭环复分解反应的步骤 的通式（IX）的化合物，其中氨基被R 5保护，然后使R 4和（如果有的话）R 5脱保护，得到由通式（XIV）表示的v-内网络胺化合物，和（3） 通式（XIV）与通式（XV）表示的化合物反应，得到通式（II）的化合物。

公开(公告)号：US20110153841A1

公开(公告)日：2011-06-23

申请号：US12737891

申请日：2009-08-28

申请人： Suguru Yoshida

发明人： Suguru Yoshida

IPC分类号： G06F15/16

CPC分类号： H04L12/4625 ,  H04L12/4641 ,  H04L12/66 ,  H04L41/0806 ,  H04L61/103

摘要： A manipulation terminal is connected to a relay apparatus which is a target of operation setting, through a communication cable, and an address resolution request of which a target is an arbitrary IP address is broadcast-transmitted to the relay apparatus by the manipulation terminal. On the other hand, the relay apparatus performs a process of storing the target address of the address resolution request as a communication address and returning a MAC address of the relay apparatus to the manipulation terminal. A communication session is established between the manipulation terminal and the relay apparatus using the MAC address returned in this way, and the manipulation terminal performs the operation setting process through telnet.

摘要翻译： 操作终端通过通信电缆连接到作为操作设置的目标的中继装置，并且通过操纵终端将目标是任意IP地址的地址解析请求广播发送到中继装置。 另一方面，中继装置执行将地址解析请求的目标地址存储为通信地址并将中继装置的MAC地址返回到操作终端的处理。 使用以这种方式返回的MAC地址，在操纵终端和中继装置之间建立通信会话，并且操作终端通过telnet执行操作设置处理。

公开(公告)号：US20070017609A1

公开(公告)日：2007-01-25

申请号：US11490955

申请日：2006-07-21

申请人： Manabu Kubota ,  Suguru Yoshida ,  Toshimi Tarui ,  Hideki Matsuda ,  Koki Mizuno ,  Tadashi Ohya

发明人： Manabu Kubota ,  Suguru Yoshida ,  Toshimi Tarui ,  Hideki Matsuda ,  Koki Mizuno ,  Tadashi Ohya

IPC分类号： C22C38/12

CPC分类号： C22C38/02 ,  C21D1/18 ,  C21D9/0093 ,  C22C38/04 ,  C22C38/12 ,  F16B35/00

摘要： Steel and steel shaped articles with an excellent delayed fracture resistance and a tensile strength of the 1600 MPa class or more, containing, by mass %, C: 0.20 to 0.60%, Si: 0.50% or less, Mn: over 0.10% to 3%, Al: 0.005 to 0.1%, Mo: over 3.0% to 10%, and, as needed, one or more of W: 0.01 to 10%, V: 0.05 to 1%, Ti: 0.01 to 1%, Nb: 0.01 to 1%, Cr: 0.10 to 2%, Ni: 0.05 to 1%, Cu: 0.05 to 0.5%, and B: 0.0003 to 0.01%, and a balance of Fe and unavoidable impurities and, further, a method of production comprising shaping the above steel to a desired shape (for example, a bolt shape), quenching it, then tempering it at 500 to 750° C. in temperature range.

摘要翻译： 具有优异的延迟抗断裂性和1600MPa级以上的抗拉强度的钢和钢制品，以质量％计含有C：0.20〜0.60％，Si：0.50％以下，Mn：超过0.10％〜3％ ％，Al：0.005〜0.1％，Mo：3.0％〜10％，W：0.01〜10％，V：0.05〜1％，Ti：0.01〜1％，Nb： 0.01〜1％，Cr：0.10〜2％，Ni：0.05〜1％，Cu：0.05〜0.5％，B：0.0003〜0.01％，余量由Fe和不可避免的杂质构成， 包括将上述钢成形为期望的形状（例如螺栓形状），淬火，然后在温度范围内在500-750℃下回火。

公开(公告)号：US20050088012A1

公开(公告)日：2005-04-28

申请号：US10989426

申请日：2004-11-17

申请人： Suguru Yoshida

发明人： Suguru Yoshida

IPC分类号： B62D21/15 ,  B62D25/04 ,  B60J7/00

CPC分类号： B62D25/04 ,  B62D21/15

摘要： In a vehicle front pillar including inner and outer frame members joined into a substantial tubular shape, a fore portion of the inner frame member is oriented toward the front of the vehicle and has at least one bent portion formed thereon so as to serve as a shock absorbing section. Rear portion of the inner frame member is oriented toward the back of the vehicle and has a reinforcing member of a closed sectional structure attached thereto so as to serve as a high-rigidity section. The reinforcing member may have a circular or rectangular cross-sectional shape.

公开(公告)号：US06854790B2

公开(公告)日：2005-02-15

申请号：US09725447

申请日：2000-11-30

申请人： Suguru Yoshida

发明人： Suguru Yoshida

IPC分类号： B62D21/15 ,  B62D25/04 ,  B62D25/00

CPC分类号： B62D25/04 ,  B62D21/15

摘要： In a vehicle front pillar including inner and outer frame members joined into a substantial tubular shape, a fore portion of the inner frame member is oriented toward the front of the vehicle and has at least one bent portion formed thereon so as to serve as a shock absorbing section. Rear portion of the inner frame member is oriented toward the back of the vehicle and has a reinforcing member of a closed sectional structure attached thereto so as to serve as a high-rigidity section. The reinforcing member may have a circular or rectangular cross-sectional shape.

摘要翻译： 在包括被连接成大致管状的内框架构件和外框架构件的车辆前柱中，内框架构件的前部朝向车辆的前部定向，并且具有形成在其上的至少一个弯曲部分，以用作冲击 吸收部分。 内框架构件的后部朝向车辆的后部定向，并且具有附接到其上的封闭截面结构的加强构件，以用作高刚性区段。 加强构件可以具有圆形或矩形横截面形状。

公开(公告)号：US06340200B1

公开(公告)日：2002-01-22

申请号：US09711535

申请日：2000-11-14

申请人： Kouji Enomoto ,  Suguru Yoshida

发明人： Kouji Enomoto ,  Suguru Yoshida

IPC分类号： B60J700

CPC分类号： B62D21/15 ,  B60J10/70 ,  B60J10/76 ,  B60J10/79 ,  B60J10/87 ,  B60R21/34 ,  B60R2021/343 ,  B62D25/04

摘要： A pillar outer of a front pillar of an automotive vehicle comprises a stiffener and a flange portion connecting to a pillar inner. A peripheral portion of a windshield is fixed to a front face (a face orienting outwardly of the vehicle) of the flange portion via a plastically deformable member which can be deformed easily and plastically when a load is applied thereto in a longitudinal direction of the vehicle body. When an impact generated when an obstacle comes to interfere with the windshield is transmitted to the plastically deformable member, the plastically deformable member is easily press collapsed by the load, and the impact that is to be received by the windshield and the obstacle can be absorbed through the impact absorbing action. In addition, since the front face of the peripheral portion of the windshield is disposed flush with an outer wall portion of the pillar outer, a connecting portion between the two members is made flush with those members to thereby reduce the air drag thereat.

摘要翻译： 机动车辆前柱的外柱包括加强件和连接到支柱内部的凸缘部分。 挡风玻璃的周边部分经由塑性变形构件固定到凸缘部分的前表面（面向车辆外侧的面），当在车辆的纵向方向上施加负载时，该塑性变形构件可容易且塑性地变形 身体。 当障碍物与挡风玻璃相干时产生的冲击被传递到塑性变形构件，塑性变形构件容易被载荷压缩，并且可以吸收由挡风玻璃和障碍物接收的冲击 通过冲击吸收动作。 此外，由于挡风玻璃的周边部分的前表面与柱外壁的外壁部分齐平地设置，所以两个构件之间的连接部分与这些构件齐平，从而减少了其上的空气阻力。

公开(公告)号：US5421920A

公开(公告)日：1995-06-06

申请号：US124097

申请日：1993-09-20

申请人： Kohichi Yamamoto ,  Suguru Yoshida ,  Kazuo Watanabe

发明人： Kohichi Yamamoto ,  Suguru Yoshida ,  Kazuo Watanabe

IPC分类号： C21C7/04 ,  B22D11/00 ,  B22D11/10 ,  B22D11/108 ,  C21C7/00 ,  C21C7/06 ,  C21D8/00 ,  C21D9/00 ,  C22C33/00 ,  C22C33/04 ,  C22C38/00 ,  C22C38/04 ,  C22C38/12 ,  C22C38/14

CPC分类号： C22C38/12 ,  C21D8/00 ,  C21D9/0068 ,  C22C38/04 ,  C22C38/14

摘要： After a predeoxidation treatment of a molten steel comprising as basic ingredients, in terms of % by weight, 0.04 to 0.20% of C, 0.05 to 0.50% of Si, 0.4 to 2.0% of Mn, 0.3 to 0.7% of Mo, 0.003 to 0.015% of N, 0.04 to 0.20% of V and less than 0.005% of Al to regulate [O %] to 0.003 to 0.015% by weight, titanium is added thereto so as to satisfy a requirement represented by the formula: -0.006.ltoreq.[Ti %]-2[O %].ltoreq.0.008 to crystallize a titanium-based oxide in an amount of 20 particles/mm.sup.2 or more, and MnS, TiN and V(C, N) are deposited on the titanium-based oxide to disperse the titanium-based oxide as a composite precipitate in the steel to provide a cast slab, and a high-strength high-toughness shape steel having an excellent fire resistance is provided by a combination of water cooling between rolling passes at the time of rolling with accelerated cooling after the completion of the rolling.

摘要翻译： 对包含作为碱性成分的钢水进行预脱氧处理后，以重量％计，C：0.04〜0.20％，Si：0.05〜0.50％，Mn：0.4〜2.0％，Mo：0.3〜0.7％，0.003〜 0.015％的N，0.04〜0.20％的V和小于0.005％的Al以将[O％]调节至0.003〜0.015％（重量），从而满足下式所示的钛：-0.006 < / = [Ti％] -2 [O％] = 0.008以使20重量/ mm 2以上的钛系氧化物结晶，并且在钛上沉积MnS，TiN和V（C，N） 的氧化物以将钛基氧化物作为复合沉淀物分散在钢中以提供铸坯，并且通过在轧制道次之间的水冷的组合提供具有优异耐火性的高强度高韧性形状钢 轧制完成后加速冷却的轧制时间。

公开(公告)号：US5150944A

公开(公告)日：1992-09-29

申请号：US683536

申请日：1991-04-10

申请人： Suguru Yoshida ,  Isao Tsunoda ,  Shoichi Sano

发明人： Suguru Yoshida ,  Isao Tsunoda ,  Shoichi Sano

IPC分类号： B62D29/00 ,  B62D29/04 ,  F16B5/01 ,  F16B5/02

CPC分类号： B62D29/001 ,  B62D29/048 ,  F16B5/01 ,  F16B5/02

摘要： A joint structure includes a sandwiched structural body comprising a core layer having opposite surfaces and a pair of first and second outer skin layers covering the opposite surfaces, respectively, and a substantially concave joint region defined in the first outer skin layer and comprising a side wall and a bottom wall contiguous to the side wall, the bottom wall being joined to the second outer skin layer. The side wall of the joint region is of a tapered shape. The sandwiched structural body is formed primarily of synthetic resins, and may additionally include reinforcing fibers.

摘要翻译： 接头结构包括夹层结构体，其包括具有相对表面的芯层和分别覆盖相对表面的一对第一和第二外皮层以及限定在第一外皮层中的基本上凹形接合区域，并且包括侧壁 以及与所述侧壁相邻的底壁，所述底壁连接到所述第二外表皮层。 接合区域的侧壁呈锥形。 夹层结构体主要由合成树脂形成，并且还可以包括增强纤维。