摘要:
This invention features compounds of formula (I): pharmaceutical compositions of the compounds, and methods of using the compounds for the treatment of, inter alia, IL-12-related diseases and disorders.
摘要:
Disclosed is an anti-cancer compound represented by Structural Formula (I): The variables in Structural Formula (I) are described hereinbelow. Also disclosed is a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by Structural Formula (I) (preferably an effective amount). Also disclosed is a method of treating a subject with cancer by administering to the subject an effective amount of a compound represented by Structural Formula (I).
摘要:
The present invention provides polymer composites reinforced with high aspect ratio reinforcing fillers selected from calcium phosphate nanofibers, nanoplates, submicron fibers, submicron plates, and combinations thereof. The mechanical and biological properties of the inventive composites are enhanced significantly over current polymer composites and may be employed in various biomedical applications, such as dental restorations.
摘要:
The present invention provides an access point device and system for a wireless local area network, and related methods thereof. On the access point device, a same ESS is divided into a plurality of VLANs, wherein the access point device comprises a broadcast key management module which is used for managing broadcast keys encrypting broadcast information and a broadcast key storage device which is used for storing the broadcast keys. The broadcast keys are stored in the broadcast key storage device in a way of corresponding to VLAN IDs of the VLANs, and the broadcast key management module can obtain the corresponding broadcast keys through the VLAN IDs.
摘要:
A base station of a wireless system comprises a local clock source and timing circuitry coupled to the local clock source. The timing circuitry is configured to adjust at least one parameter of the local clock source based at least in part on timing information extracted from designated portions of each of one or more frames of a synchronous transport signal received in the base station. The base station may further comprise a physical layer device, such as a mapper, configured to extract the timing information from the designated portions of each of the one or more frames of the synchronous transport signal. The designated portions of the one or more frames of the synchronous transport signal from which the timing information is extracted may comprise designated overhead bytes of the one or more frames, such as, for example, transport overhead (TOH) bytes.
摘要:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
摘要:
An electronic module to be mounted on a mounting surface may include: a circuit board provided with a heat source, wherein a thermal via is formed through the circuit board and is in thermal contact with the heat source; and a potting material packaging the circuit board at least at the other side opposite to one side of heat source, wherein the potting material has a recess formed in at least part of an area corresponding to the thermal via at the other side of the circuit board and a thermal conductive material, which is thermal-conductively connected to the mounting surface, is filled in the recess.
摘要:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
摘要:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
摘要:
Described herein are composites that inhibit or reduce adhesion between two or more tissues. Also described herein are methods of using the composites.