公开(公告)号：US5601983A

公开(公告)日：1997-02-11

申请号：US395631

申请日：1995-02-28

申请人： Hidehito Takayama ,  Matsuomi Nishimura ,  Kazumi Tanaka ,  Toshikazu Ohnishi ,  Takeshi Miyazaki

发明人： Hidehito Takayama ,  Matsuomi Nishimura ,  Kazumi Tanaka ,  Toshikazu Ohnishi ,  Takeshi Miyazaki

IPC分类号： G01N33/543 ,  G01N33/58 ,  C12Q1/68

CPC分类号： G01N33/582 ,  G01N33/585 ,  Y10S435/961 ,  Y10S435/968 ,  Y10S436/80 ,  Y10S436/804 ,  Y10S436/805 ,  Y10S436/823

摘要： In a method for measuring a specified component in a specimen by reacting the specimen with a first reagent formed by binding a substance active to the specified component, with carrier particles and a second reagent formed by labelling a substance active to the specified component with a first label, and measuring the substances in the complexes obtained in the reaction, there is disclosed a method featured by labelling the carrier particles with a second label different from the first label, and detecting the second label and then the first label utilizing the detection of the second label as a trigger.This method enables a highly precise measurement without the influence of noise components in the detection of specified trace components in the specimen, utilizing an antigen-antibody reaction or a nucleic acid hybridization.

摘要翻译： 在通过使样本与通过结合对特定成分有活性的物质结合而形成的第一试剂与载体颗粒和通过将具有活性的物质标记在特定成分上而形成的第二试剂的方法中， 标记和测量在反应中获得的络合物中的物质，公开了一种特征在于用不同于第一标记的第二标记标记载体颗粒的方法，并且利用第二标记的检测来检测第二标记 第二个标签作为触发器。 该方法利用抗原抗体反应或核酸杂交，能够在不受噪声成分影响的情况下进行高精度测定。

公开(公告)号：US5427959A

公开(公告)日：1995-06-27

申请号：US769366

申请日：1991-10-01

申请人： Matsuomi Nishimura ,  Kazumi Tanaka ,  Takeshi Miyazaki ,  Hidehito Takayama ,  Toshikazu Ohnishi

发明人： Matsuomi Nishimura ,  Kazumi Tanaka ,  Takeshi Miyazaki ,  Hidehito Takayama ,  Toshikazu Ohnishi

IPC分类号： G01N15/00 ,  G01N15/02 ,  G01N15/04 ,  G01N21/03 ,  G01N33/53 ,  G01N33/543 ,  G01N33/546

CPC分类号： G01N33/54366 ,  B01L3/5027 ,  G01N21/03 ,  G01N33/5304 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2400/0406 ,  G01N15/0255 ,  G01N2015/0053 ,  G01N2015/0065 ,  G01N2015/0092 ,  G01N2015/045 ,  G01N2021/0346 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/809 ,  Y10S436/81 ,  Y10S436/824 ,  Y10S436/908

摘要： On a slab-like board formed of a transparent material is closely attached a wedge-shaped transparent cover member provided with a recess in a central inner portion, thereby to form a clearance. The height of the clearance between the recess and the board is configured to decrease continuously or in steps. When an immunological active substance such as a monoclonal antibody is caused to sensitize carrier particles F, and a reagent having the carrier particles F dispersed into a liquid medium mainly composed of the water is mixed with a specimen, the reaction will occur in which the flocculate is formed from plural carrier particles. When this reaction liquid is poured into the clearance through the opening, the reaction liquid penetrates in the direction having a narrower vertical spacing due to surface tension. A single carrier particle unflocculated can move deep within the recess because it is small in diameter, but the flocculate G is trapped on its way and can not move because of its size.

摘要翻译： 在由透明材料形成的板状板上紧密地连接有在中心内部设置有凹部的楔形透明盖构件，从而形成间隙。 凹槽和板之间的间隙的高度被配置为连续或逐步减小。 当使诸如单克隆抗体的免疫活性物质使载体颗粒F致敏时，将分散在主要由水组成的液体介质中的载体颗粒F的试剂与样品混合时，将发生絮凝反应 由多个载体颗粒形成。 当该反应液通过开口倒入间隙中时，由于表面张力，反应液体沿着垂直间隔较窄的方向渗透。 未絮凝的单载体颗粒由于其直径小而在凹槽内深深移动，而是絮凝的G被捕获，因为其尺寸不能移动。

公开(公告)号：US5380490A

公开(公告)日：1995-01-10

申请号：US821049

申请日：1992-01-16

申请人： Hiroaki Hoshi ,  Matsuomi Nishimura ,  Kazumi Tanaka ,  Takeshi Miyazaki ,  Toshikazu Ohnishi ,  Hidehito Takayama

发明人： Hiroaki Hoshi ,  Matsuomi Nishimura ,  Kazumi Tanaka ,  Takeshi Miyazaki ,  Toshikazu Ohnishi ,  Hidehito Takayama

IPC分类号： G01N21/59 ,  G01N21/82 ,  G01N33/53 ,  G01N33/543

CPC分类号： G01N33/5438 ,  G01N21/82 ,  G01N33/5304 ,  G01N33/54313 ,  G01N2021/5953 ,  G01N2021/5957

摘要： An apparatus is so constructed as to measure a specific substance in a test specimen by the degree of the aggregation of carrier particles in a reaction solution in which the test specimen is mixed with the carrier particles which carry a substance specifically binding to the specific substance. The apparatus includes a substrate having comb-shaped electrodes mounting the reaction solution and amplifier and alternating oscillator for displaying a variable voltage to the comb-shaped electrodes. The test specimen measuring apparatus having the structure accelerates the aggregation of the reaction solution by applying an alternating voltate to the comb-shaped electrodes in a state that the reaction solution is being mounted on the substrate, and detects the spatial spectrum of the comb-shaped electrodes on which the reaction solution is mounted, thus performing the qualitative or quantitative detection of the presence of the substance in the test specimen.

摘要翻译： 一种装置被构造成通过载体颗粒在其中将试样与携带特异性结合物质的物质的载体颗粒混合的反应溶液中聚集的程度来测量试样中的特定物质。 该装置包括具有安装反应溶液的梳形电极的基板和用于向梳状电极显示可变电压的放大器和交替振荡器。 具有这种结构的试样测量装置在将反应溶液安装在基板上的状态下通过向梳状电极施加交流电压来加速反应溶液的聚集，并且检测梳形电极的空间光谱 在其上安装反应溶液的电极，从而进行定性或定量检测试样中物质的存在。

公开(公告)号：US5272552A

公开(公告)日：1993-12-21

申请号：US347920

申请日：1989-05-05

申请人： Kazuo Yoshinaga ,  Yutaka Kurabayashi ,  Kazuo Isaka ,  Shuzo Kaneko ,  Akihiro Mouri ,  Yomishi Toshida ,  Toshikazu Ohnishi ,  Takeo Eguchi

发明人： Kazuo Yoshinaga ,  Yutaka Kurabayashi ,  Kazuo Isaka ,  Shuzo Kaneko ,  Akihiro Mouri ,  Yomishi Toshida ,  Toshikazu Ohnishi ,  Takeo Eguchi

IPC分类号： G02F1/133 ,  G02F1/1333 ,  G11B7/0025 ,  G11B7/0055 ,  G02F1/13

CPC分类号： G02F1/132 ,  G02F1/133365 ,  G11B7/0025 ,  G11B7/00555

摘要： An optical modulation device is provided by forming an optical modulation layer comprising a polymer liquid crystal having a helical structure and a non-helical structure in chiral smectic C phase. The helical structure of the polymer liquid crystal is selectively formed or removed to provide a recorded state. The recorded state is held below the glass transition point of the polymer liquid crystal. The helical pitch of the helical structure can be selectively changed to form a recorded state. The helical structure can be formed to dispose its principal axis perpendicularly to the polymer liquid crystal layer. The recorded state may be read out by detecting a reflectance from the polymer liquid crystal layer.

公开(公告)号：US5038166A

公开(公告)日：1991-08-06

申请号：US291443

申请日：1988-12-28

申请人： Kazuo Isaka ,  Shuzo Kaneko ,  Akihiro Mouri ,  Kazuo Yoshinaga ,  Toshikazu Ohnishi ,  Yutaka Kurabayashi ,  Yomishi Toshida ,  Takeo Eguchi

发明人： Kazuo Isaka ,  Shuzo Kaneko ,  Akihiro Mouri ,  Kazuo Yoshinaga ,  Toshikazu Ohnishi ,  Yutaka Kurabayashi ,  Yomishi Toshida ,  Takeo Eguchi

IPC分类号： G02F1/1333 ,  G03F1/00 ,  G06K15/12 ,  G11B7/25

CPC分类号： G11B7/25 ,  G02F1/133365 ,  G03F7/202 ,  G06K15/1238

摘要： An optical image recording apparatus includes an image holding member comprising a polymer recording layer capable of recording and holding data through heat application, thermal recording means for applying heat to the polymer recording layer, a photosensitive member, and exposure means for recording the data recorded by the recording layer by the photosensitive member. The polymer recording layer is preferably composed from a polymer liquid crystal. The polymer recording layer and the photosensitivie member can be provided in a laminated form. The data recorded on the photosensitive member may be subjected to an electrophotographic image forming process.

摘要翻译： 光学图像记录装置包括图像保持部件，该图像保持部件包括能够通过热施加记录和保持数据的聚合物记录层，用于向聚合物记录层施加热量的热敏记录装置，感光部件和用于记录由 记录层由感光构件。 聚合物记录层优选由聚合物液晶组成。 聚合物记录层和光敏元件可以以层压形式提供。 记录在感光构件上的数据可以进行电子照相图像形成处理。

公开(公告)号：US4920361A

公开(公告)日：1990-04-24

申请号：US214374

申请日：1988-06-24

申请人： Kohzoh Arahara ,  Hiroshi Fukumoto ,  Toshiya Yuasa ,  Toshikazu Ohnishi ,  Fumitaka Kan, deceased ,  Hiroshi Tanioka ,  Norihiko Koizumi ,  Noboru Tohyama

发明人： Kohzoh Arahara ,  Hiroshi Fukumoto ,  Toshiya Yuasa ,  Toshikazu Ohnishi ,  Fumitaka Kan, deceased ,  Hiroshi Tanioka ,  Norihiko Koizumi ,  Noboru Tohyama

IPC分类号： B41C1/10 ,  B41M5/025 ,  B41M5/26 ,  B41M5/382 ,  C09D11/02

CPC分类号： B41M5/38207 ,  B41C1/105

摘要： An image recording method and an image recording apparatus using an ink which is substantially non-adhesive but can be imparted with an adhesiveness when subjected to a pH change. In the image recording method, the ink is subjected to a pattern of pH change to be provided with an adhesive pattern, which is then transferred to a recording medium, such as plain paper, directly or by the medium of an intermediate transfer medium to form an ink pattern corresponding to the pH change pattern.

公开(公告)号：US06780073B2

公开(公告)日：2004-08-24

申请号：US10112720

申请日：2002-04-02

申请人： Miki Tamura ,  Toshikazu Ohnishi ,  Kazuhiro Jindai

发明人： Miki Tamura ,  Toshikazu Ohnishi ,  Kazuhiro Jindai

IPC分类号： H01J900

CPC分类号： H01J9/027

摘要： A method of manufacturing an electron-emitting device includes a process for forming a pair of electric conductors spaced from each other on a substrate, and an activation process for forming a film of carbon or a carbon compound on at least one of the pair of electric conductors. The activation process is sequentially performed within plural containers having different atmospheres.

摘要翻译： 一种制造电子发射器件的方法包括在衬底上形成彼此间隔开的一对电导体的工艺，以及用于在所述一对电极中的至少一个上形成碳或碳化合物的膜的活化工艺 导体 激活过程在具有不同气氛的多个容器内依次进行。

公开(公告)号：US06419539B1

公开(公告)日：2002-07-16

申请号：US09512641

申请日：2000-02-24

申请人： Miki Tamura ,  Toshikazu Ohnishi ,  Kazuhiro Jindai

发明人： Miki Tamura ,  Toshikazu Ohnishi ,  Kazuhiro Jindai

IPC分类号： H01J902

CPC分类号： H01J9/027

摘要： A method of manufacturing an electron-emitting device includes a process for forming a pair of electric conductors spaced from each other on a substrate, and an activation process for forming a film of carbon or a carbon compound on at least one of the pair of electric conductors. The activation process is sequentially performed within plural containers having different atmospheres.

摘要翻译： 一种制造电子发射器件的方法包括在衬底上形成彼此间隔开的一对电导体的工艺，以及用于在所述一对电极中的至少一个上形成碳或碳化合物的膜的活化工艺 导体 激活过程在具有不同气氛的多个容器内依次进行。

公开(公告)号：US5812227A

公开(公告)日：1998-09-22

申请号：US41258

申请日：1993-04-01

申请人： Yomishi Toshida ,  Kazuo Yoshinaga ,  Toshikazu Ohnishi ,  Koichi Sato ,  Takeo Eguchi ,  Tsuyoshi Shibata

发明人： Yomishi Toshida ,  Kazuo Yoshinaga ,  Toshikazu Ohnishi ,  Koichi Sato ,  Takeo Eguchi ,  Tsuyoshi Shibata

IPC分类号： C09K19/54 ,  G02F1/1334 ,  G02F1/137

CPC分类号： C09K19/544 ,  G02F1/1334 ,  C09K2019/546 ,  G02F2001/13345

摘要： The liquid crystal device is constituted by disposing a display layer between a pair of electrode plates. The display layer comprises a porous polymer material having open pores partially filled and a low-molecular weight mesomorphic compound impregnating the porous polymer material. The display layer is free from an unfilled portion of the low-molecular weight mesomorphic compound to be effective for providing a liquid crystal device showing a high transmittance and a good contrast. The display layer also comprises a three dimensional network structure coated with a polymer layer, and a low-molecular weight mesomorphic compound impregnating the three-dimensional network structure. The display layer is free from a fibrous part which is unstable against an applied voltage to be effective for providing a liquid crystal device showing no hysteresis.

摘要翻译： 液晶装置通过在一对电极板之间设置显示层而构成。 显示层包括具有部分填充的开放孔的多孔聚合物材料和浸渍多孔聚合物材料的低分子量介晶化合物。 显示层不含低分子量介晶化合物的未填充部分，对于提供显示高透射率和良好对比度的液晶装置是有效的。 显示层还包括涂覆有聚合物层的三维网状结构和浸渍三维网状结构的低分子量介晶化合物。 显示层没有纤维部分，对于施加的电压是不稳定的，以有效地提供不显示滞后的液晶装置。

公开(公告)号：US5700647A

公开(公告)日：1997-12-23

申请号：US568680

申请日：1995-12-07

申请人： Takeshi Miyazaki ,  Kazumi Tanaka ,  Tsuyoshi Santo ,  Toshikazu Ohnishi ,  Tetsuro Fukui ,  Tadashi Okamoto

发明人： Takeshi Miyazaki ,  Kazumi Tanaka ,  Tsuyoshi Santo ,  Toshikazu Ohnishi ,  Tetsuro Fukui ,  Tadashi Okamoto

IPC分类号： C12Q1/68 ,  G01N33/533 ,  G01N33/58

CPC分类号： G01N33/582 ,  C12Q1/6816 ,  G01N33/533 ,  G01N33/583 ,  Y10T436/21

摘要： To provide a reagent with excellent stability under storage, which can detect a subject compound to be measured with higher specificity and sensitibity. Complexes of a compound represented by the general formula (IV): ##STR1##

摘要翻译： 提供在储存下具有优异稳定性的试剂，其可以以更高的特异性和敏感性检测待测化合物。 由通式（IV）表示的化合物的配合物：（IV）